-
1
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
DOI 10.1038/90609
-
Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001;2:675-680. (Pubitemid 32747155)
-
(2001)
Nature Immunology
, vol.2
, Issue.8
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
3
-
-
0030831210
-
A human homologue of the Drosophila toll protein signals activation of adaptive immunity
-
DOI 10.1038/41131
-
Medzhitov R, Preston-Hurlburt P, Janeway CA, Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997;388:394-397. (Pubitemid 27334820)
-
(1997)
Nature
, vol.388
, Issue.6640
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
4
-
-
0032170215
-
Genetic and physical mapping of the Lps locus: Identification of the toll-4 receptor as a candidate gene in the critical region
-
DOI 10.1006/bcmd.1998.0201
-
Poltorak A, Smirnova I, He X, et al. Genetic and physicalmapping of the Lps locus: identification of the toll-4 receptor as a candidate gene in the critical region. Blood CellsMol Dis 1998;24:340-355. (Pubitemid 28524834)
-
(1998)
Blood Cells, Molecules, and Diseases
, vol.24
, Issue.3
, pp. 340-355
-
-
Poltorak, A.1
Smirnova, I.2
He, X.3
Liu, M.-Y.4
Van Huffel, C.5
Birdwell, D.6
Alejos, E.7
Silva, M.8
Du, X.9
Thompson, P.10
Chan, E.K.L.11
Ledesma, J.12
Roe, B.13
Clifton, S.14
Vogel, S.N.15
Beutler, B.16
-
5
-
-
20044368019
-
Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88
-
Hasan U, Chaffois C, Gaillard C, et al. Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88. J Immunol 2005;174:2942-2950. (Pubitemid 40279713)
-
(2005)
Journal of Immunology
, vol.174
, Issue.5
, pp. 2942-2950
-
-
Hasan, U.1
Chaffois, C.2
Gaillard, C.3
Saulnier, V.4
Merck, E.5
Tancredi, S.6
Guiet, C.7
Briere, F.8
Vlach, J.9
Lebecque, S.10
Trinchieri, G.11
Bates, E.E.M.12
-
6
-
-
12144286763
-
Toll-like receptors 9 and 3 as essential complonents of innate immune defense against mouse cytomegalovirus infection
-
DOI 10.1073/pnas.0400525101
-
Tabeta K, Georgel P, Janssen E, et al. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci USA 2004;101:3516-3521. (Pubitemid 38338227)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.10
, pp. 3516-3521
-
-
Tabeta, K.1
Georgel, P.2
Janssen, E.3
Du, X.4
Hoebe, K.5
Crozat, K.6
Mudd, S.7
Shamel, L.8
Sovath, S.9
Goode, J.10
Alexopoulou, L.11
Flavell, R.A.12
Beutler, B.13
-
7
-
-
32944464648
-
Pathogen recognition and innate immunity
-
DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
-
Akira S,Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006;124:783-801. (Pubitemid 43261452)
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
8
-
-
48749128643
-
Structures of the toll-like receptor family and its ligand complexes
-
Jin MS, Lee J-O. Structures of the toll-like receptor family and its ligand complexes. Immunity 2008;29:182-191.
-
(2008)
Immunity
, vol.29
, pp. 182-191
-
-
Jin, M.S.1
Lee, J.-O.2
-
9
-
-
0033618630
-
Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2
-
Aliprantis AO, Yang RB, Mark MR, et al. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 1999;285:736-739.
-
(1999)
Science
, vol.285
, pp. 736-739
-
-
Aliprantis, A.O.1
Yang, R.B.2
Mark, M.R.3
-
10
-
-
0036954037
-
Recognition of lipopeptides by Toll-like receptors
-
DOI 10.1179/096805102125001073
-
Takeda K, Takeuchi O, Akira S. Recognition of lipopeptides by Toll-like receptors. J Endotoxin Res 2002;8:459-463. (Pubitemid 36104601)
-
(2002)
Journal of Endotoxin Research
, vol.8
, Issue.6
, pp. 459-463
-
-
Takeda, K.1
Takeuchi, O.2
Akira, S.3
-
11
-
-
34548608447
-
Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
-
DOI 10.1016/j.cell.2007.09.008, PII S009286740701152X
-
Jin MS, Kim SE, Heo JY, et al. Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell 2007;130:1071-1082. (Pubitemid 47410281)
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1071-1082
-
-
Jin, M.S.1
Kim, S.E.2
Heo, J.Y.3
Lee, M.E.4
Kim, H.M.5
Paik, S.-G.6
Lee, H.7
Lee, J.-O.8
-
12
-
-
71749118913
-
Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
-
Kang JY, Nan X, Jin MS, et al. Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer. Immunity 2009;31:873-884.
-
(2009)
Immunity
, vol.31
, pp. 873-884
-
-
Kang, J.Y.1
Nan, X.2
Jin, M.S.3
-
13
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
-
Ozinsky A, Underhill DM, Fontenot JD, et al.The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. ProcNatl Acad Sci USA 2000;97:13766-13771.
-
(2000)
ProcNatl Acad Sci USA
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
-
14
-
-
0042346123
-
Inhibition of a p38/stress-activated protein kinase-2-dependent phosphatase restores function of IL-1 receptor-associated kinase-1 and reverses Toll-like receptor 2- and 4-dependent tolerance of macrophages
-
Ropert C, Closel M, Chaves AC, et al. Inhibition of a p38/stress-activated protein kinase-2-dependent phosphatase restores function of IL-1 receptor-associate kinase-1 and reverses Toll-like receptor 2-and 4-dependent tolerance ofmacrophages. J Immunol 2003;171:1456-1465. (Pubitemid 36900080)
-
(2003)
Journal of Immunology
, vol.171
, Issue.3
, pp. 1456-1465
-
-
Ropert, C.1
Closel, M.2
Chaves, A.C.L.3
Gazzinelli, R.T.4
-
15
-
-
13444280215
-
CD36 is a sensor of diacylglycerides
-
DOI 10.1038/nature03253
-
Hoebe K, Georgel P, Rutschmann S, et al. CD36 is a sensor of diacylglycerides. Nature 2005;433:523-527. (Pubitemid 40204309)
-
(2005)
Nature
, vol.433
, Issue.7025
, pp. 523-527
-
-
Hoebe, K.1
Georgel, P.2
Rutschmann, S.3
Du, X.4
Mudd, S.5
Crozat, K.6
Sovath, S.7
Shamel, L.8
Hartung, T.9
Zahringer, U.10
Beutler, B.11
-
16
-
-
15544369370
-
Innate immunity to the pathogenic fungus Coccidioides posadasii is dependent on Toll-like receptor 2 and Dectin-1
-
DOI 10.1128/IAI.73.3.1553-1560.2005
-
Viriyakosol S, Fierer J, Brown GD, et al. Innate immunity to the pathogenic fungus Coccidioides posadasii is dependent on Toll-like receptor 2 and Dectin-1. Infect Immun 2005;73:1553-1560. (Pubitemid 40470741)
-
(2005)
Infection and Immunity
, vol.73
, Issue.3
, pp. 1553-1560
-
-
Viriyakosol, S.1
Fierer, J.2
Brown, G.D.3
Kirkland, T.N.4
-
17
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
DOI 10.1038/35074106
-
Hayashi F, Smith KD,Ozinsky A, et al.The innate immune response to bacterial flagellin ismediated by Toll-like receptor 5. Nature 2001;410:1099-1103. (Pubitemid 32391041)
-
(2001)
Nature
, vol.410
, Issue.6832
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
Eng, J.K.7
Akira, S.8
Underhill, D.M.9
Aderem, A.10
-
18
-
-
45549099429
-
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
-
DOI 10.1038/ni.1622, PII NI.1622
-
Uematsu S, Fujimoto K, JangMH, et al. Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5. Nat Immunol 2008;9:769-776. (Pubitemid 351859160)
-
(2008)
Nature Immunology
, vol.9
, Issue.7
, pp. 769-776
-
-
Uematsu, S.1
Fujimoto, K.2
Jang, M.H.3
Yang, B.-G.4
Jung, Y.-J.5
Nishiyama, M.6
Sato, S.7
Tsujimura, T.8
Yamamoto, M.9
Yokota, Y.10
Kiyono, H.11
Miyasaka, M.12
Ishii, K.J.13
Akira, S.14
-
19
-
-
1542377424
-
A Toll-like Receptor That Prevent Infection by Uropathogenic Bacteria
-
DOI 10.1126/science.1094351
-
Zhang D, Zhang G, Hayden MS, et al. A toll-like receptor that prevents infection by uropathogenic bacteria. Science 2004;303:1522-1526. (Pubitemid 38314423)
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1522-1526
-
-
Zhang, D.1
Zhang, G.2
Hayden, M.S.3
Greenblatt, M.B.4
Bussey, C.5
Flavell, R.A.6
Ghosh, S.7
-
20
-
-
20644433342
-
Immunology: TLR11 activation of dendritic cells by a protozoan profilin-like protein
-
DOI 10.1126/science.1109893
-
Yarovinsky F, Zhang D, Andersen JF, et al. TLR11 activation of dendritic cells by a protozoan profilinlike protein. Science 2005;308:1626-1629. (Pubitemid 40807512)
-
(2005)
Science
, vol.308
, Issue.5728
, pp. 1626-1629
-
-
Yarovinsky, F.1
Zhang, D.2
Andersen, J.F.3
Bannenberg, G.L.4
Serhan, C.N.5
Hayden, M.S.6
Hieny, S.7
Sutterwala, F.S.8
Flavell, R.A.9
Ghosh, S.10
Sher, A.11
-
21
-
-
84872761427
-
Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii
-
Koblansky AA, Jankovic D, Oh H, et al. Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii. Immunity 2012;38:119-130.
-
(2012)
Immunity
, vol.38
, pp. 119-130
-
-
Koblansky, A.A.1
Jankovic, D.2
Oh, H.3
-
22
-
-
84868028801
-
Amouse model of salmonella typhi infection
-
Mathur R,OhH,ZhangD, et al.Amouse model of salmonella typhi infection.Cell 2012;151:590-602.
-
(2012)
Cell
, vol.151
, pp. 590-602
-
-
Mathur, R.1
Oh, H.2
Zhang, D.3
-
23
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
-
Wright SD, Ramos RA, Tobias PS, et al. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 1990;249:1431-1433.
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
-
24
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
DOI 10.1126/science.282.5396.2085
-
Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998;282:2085-2088. (Pubitemid 29001265)
-
(1998)
Science
, vol.282
, Issue.5396
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.-Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
Ricciardi-Castagnoli, P.12
Layton, B.13
Beutler, B.14
-
25
-
-
0034070414
-
Kupffer cell activation by lipopolysaccharide in rats: Role for lipopolysaccharide binding protein and toll-like receptor 4
-
Su GL, Klein RD, Aminlari A, et al. Kupffer cell activation by lipopolysaccharide in rats: role for lipopolysaccharide binding protein and toll-like receptor 4. Hepatology 2000;31:446-455.
-
(2000)
Hepatology
, vol.31
, pp. 446-455
-
-
Su, G.L.1
Klein, R.D.2
Aminlari, A.3
-
26
-
-
34548222514
-
Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
-
DOI 10.1016/j.cell.2007.08.002, PII S0092867407010215
-
KimHM, Park BS, Kim J-I, et al. Crystal structure of the TLR4-MD-2 complexwith bound endotoxin antagonist Eritoran. Cell 2007;130:906-917. (Pubitemid 47332573)
-
(2007)
Cell
, vol.130
, Issue.5
, pp. 906-917
-
-
Kim, H.M.1
Park, B.S.2
Kim, J.-I.3
Kim, S.E.4
Lee, J.5
Oh, S.C.6
Enkhbayar, P.7
Matsushima, N.8
Lee, H.9
Yoo, O.J.10
Lee, J.-O.11
-
27
-
-
67349182481
-
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
-
Park BS, Song DH, Kim HM, et al. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 2009;458:1191-1195.
-
(2009)
Nature
, vol.458
, pp. 1191-1195
-
-
Park, B.S.1
Song, D.H.2
Kim, H.M.3
-
28
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones EA, Popova L, Kwinn L, et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 2000;1:398-401.
-
(2000)
Nat Immunol
, vol.1
, pp. 398-401
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
-
29
-
-
0037133308
-
Murine retroviruses activate B cells via interaction with toll-like receptor 4
-
DOI 10.1073/pnas.042355399
-
Rassa JC,Meyers JL, Zhang Y, et al.Murine retroviruses activate B cells via interaction with toll-like receptor 4. Proc Natl Acad Sci USA 2002;99:2281-2286. (Pubitemid 34169052)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.4
, pp. 2281-2286
-
-
Rassa, J.C.1
Meyers, J.L.2
Zhang, Y.3
Kudaravalli, R.4
Ross, S.R.5
-
30
-
-
56549116047
-
Toll-like receptor and RIG-I-like receptor signaling
-
Kawai T, Akira S. Toll-like receptor and RIG-I-like receptor signaling. Ann NY Acad Sci 2008;1143:1-20.
-
(2008)
Ann NY Acad Sci
, vol.1143
, pp. 1-20
-
-
Kawai, T.1
Akira, S.2
-
31
-
-
34548699323
-
TLR3 deficiency in patients with herpes simplex encephalitis
-
DOI 10.1126/science.1139522
-
Zhang S-Y, JouanguyE,Ugolini S, et al.TLR3deficiency in patientswith herpes simplex encephalitis. Science 2007;317:1522-1527. (Pubitemid 47417427)
-
(2007)
Science
, vol.317
, Issue.5844
, pp. 1522-1527
-
-
Zhang, S.-Y.1
Jouanguy, E.2
Ugolini, S.3
Smahi, A.4
Elain, G.5
Romero, P.6
Segal, D.7
Sancho-Shimizu, V.8
Lorenzo, L.9
Puel, A.10
Picard, C.11
Chapgier, A.12
Plancoulaine, S.13
Titeux, M.14
Cognet, C.15
Von Bernuth, H.16
Ku, C.-L.17
Casrouge, A.18
Zhang, X.-X.19
Barreiro, L.20
Leonard, J.21
Hamilton, C.22
Lebon, P.23
Heron, B.24
Vallee, L.25
Quintana-Murci, L.26
Hovnanian, A.27
Rozenberg, F.28
Vivier, E.29
Geissmann, F.30
Tardieu, M.31
Abel, L.32
Casanova, J.-L.33
more..
-
32
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
DOI 10.1038/35099560
-
Alexopoulou L, Holt AC,Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001;413:732-738. (Pubitemid 33009951)
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
33
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
DOI 10.1038/ni1087
-
Yoneyama M, Kikuchi M, Natsukawa T, et al.The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004;5:730-737. (Pubitemid 39023305)
-
(2004)
Nature Immunology
, vol.5
, Issue.7
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
Taira, K.7
Akira, S.8
Fujita, T.9
-
34
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama M, Kikuchi M, Matsumoto K, et al. Shared and unique functions of the DExD/Hbox helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 2005;175:2851-2858. (Pubitemid 41170502)
-
(2005)
Journal of Immunology
, vol.175
, Issue.5
, pp. 2851-2858
-
-
Yoneyama, M.1
Kikuchi, M.2
Matsumoto, K.3
Imaizumi, T.4
Miyagishi, M.5
Taira, K.6
Foy, E.7
Loo, Y.-M.8
Gale Jr., M.9
Akira, S.10
Yonehara, S.11
Kato, A.12
Fujita, T.13
-
35
-
-
84855918194
-
Regulation ofRLR-mediated innate immune signaling-it is all about keeping the balance
-
EisenacherK,KrugA.Regulation ofRLR-mediated innate immune signaling-it is all about keeping the balance. Eur J Cell Biol 2012;91:36-47.
-
(2012)
Eur J Cell Biol
, vol.91
, pp. 36-47
-
-
Eisenacher, K.1
Krug, A.2
-
36
-
-
79956314622
-
Immune signaling by RIG-I-like receptors
-
Loo YM, Gale M, Jr. Immune signaling by RIG-I-like receptors. Immunity 2011;34:680-692.
-
(2011)
Immunity
, vol.34
, pp. 680-692
-
-
Loo, Y.M.1
Gale Jr., M.2
-
37
-
-
23044445303
-
Structural biology: Crystal structure of human toll-like receptor 3 (TLR3) ectodomain
-
DOI 10.1126/science.1115253
-
Choe J, Kelker MS, Wilson IA. Crystal structure of human toll-like receptor 3 (TLR3) ectodomain. Science 2005;309:581-585. (Pubitemid 41033635)
-
(2005)
Science
, vol.309
, Issue.5734
, pp. 581-585
-
-
Choe, J.1
Kelker, M.S.2
Wilson, I.A.3
-
38
-
-
33745048928
-
The dsRNA binding site of human Toll-like receptor 3
-
DOI 10.1073/pnas.0603245103
-
Bell JK, Askins J,Hall PR, et al.The dsRNA binding site of human Toll-like receptor 3. ProcNatl Acad Sci USA 2006;103:8792-8797. (Pubitemid 43878098)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.23
, pp. 8792-8797
-
-
Bell, J.K.1
Askins, J.2
Hall, P.R.3
Davies, D.R.4
Segal, D.M.5
-
39
-
-
1542317550
-
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
-
DOI 10.1126/science.1093616
-
Diebold SS,Kaisho T,HemmiH, et al. Innate antiviral responses bymeans of TLR7-mediated recognition of single-stranded RNA. Science 2004;303:1529-1531. (Pubitemid 38314425)
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis E Sousa, C.5
-
40
-
-
1542317578
-
Species-Specific Recognition of Single-Stranded RNA via Till-like Receptor 7 and 8
-
DOI 10.1126/science.1093620
-
Heil F,HemmiH,Hochrein H, et al. Species-specific recognition of single-strandedRNAvia toll-like receptor 7 and 8. Science 2004;303:1526-1529. (Pubitemid 38314424)
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
41
-
-
20144389695
-
Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
-
DOI 10.1038/nm1191
-
Hornung V, Guenthner-Biller M, Bourquin C, et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med 2005;11:263-270. (Pubitemid 40460553)
-
(2005)
Nature Medicine
, vol.11
, Issue.3
, pp. 263-270
-
-
Hornung, V.1
Guenthner-Biller, M.2
Bourquin, C.3
Ablasser, A.4
Schlee, M.5
Uematsu, S.6
Noronha, A.7
Manoharan, M.8
Akira, S.9
De Fougerolles, A.10
Endres, S.11
Hartmann, G.12
-
42
-
-
31344461659
-
Innate immune recognition of viral infection
-
DOI 10.1038/ni1303, PII N1303
-
Kawai T, Akira S. Innate immune recognition of viral infection. Nat Immunol 2006;7:131-137. (Pubitemid 43135878)
-
(2006)
Nature Immunology
, vol.7
, Issue.2
, pp. 131-137
-
-
Kawai, T.1
Akira, S.2
-
43
-
-
0037013830
-
Interferon-α and interleukin-12 are induced differentially by toll-like receptor 7 ligands in human blood dendritic cell subsets
-
DOI 10.1084/jem.20020207
-
Ito T, Amakawa R, Kaisho T, et al. Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets. J ExpMed 2002;195:1507-1512. (Pubitemid 34602828)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.11
, pp. 1507-1512
-
-
Ito, T.1
Amakawa, R.2
Kaisho, T.3
Hemmi, H.4
Tajima, K.5
Uehira, K.6
Ozaki, Y.7
Tomizawa, H.8
Akira, S.9
Fukuhara, S.10
-
44
-
-
0036008014
-
Small-antiviral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
DOI 10.1038/ni758
-
Hemmi H, Kaisho T, Takeuchi O, et al. Small anti-viral compounds activate immune cells via the TLR7MyD88-dependent signaling pathway. Nat Immunol 2002;3:196-200. (Pubitemid 34141451)
-
(2002)
Nature Immunology
, vol.3
, Issue.2
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
Sato, S.4
Sanjo, H.5
Hoshino, K.6
Horiuchi, T.7
Tomizawa, H.8
Takeda, K.9
Akira, S.10
-
45
-
-
37048998555
-
Matrix protein mediated shutdown of host cell metabolism limits vesicular stomatitis virus-induced interferon-alpha responses to plasmacytoid dendritic cells
-
DOI 10.1016/j.imbio.2007.09.003, PII S0171298507001040, Macrophage and Dendritic Cells
-
Waibler Z, Detje CN, Bell JC, Kalinke U.Matrix protein mediated shutdown of host cell metabolism limits vesicular stomatitis virus-induced interferon-alpha responses to plasmacytoid dendritic cells. Immunobiology 2007;212:887-894. (Pubitemid 350246253)
-
(2008)
Immunobiology
, vol.212
, Issue.9-10
, pp. 887-894
-
-
Waibler, Z.1
Detje, C.N.2
Bell, J.C.3
Kalinke, U.4
-
46
-
-
58149116611
-
Functional characterization of ex vivo blood myeloid and plasmacytoid dendritic cells after infection with dengue virus
-
Sun P, Fernandez S, Marovich MA, et al. Functional characterization of ex vivo blood myeloid and plasmacytoid dendritic cells after infection with dengue virus. Virology 2009;383:207-215.
-
(2009)
Virology
, vol.383
, pp. 207-215
-
-
Sun, P.1
Fernandez, S.2
Marovich, M.A.3
-
47
-
-
84861325064
-
The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via aMYD88-dependent TLR7/8-independent signaling pathway
-
Ruscanu S, Pascale F, Bourge M, et al.The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via aMYD88-dependent TLR7/8-independent signaling pathway. J Virology 2012;86:5817-5828.
-
(2012)
J Virology
, vol.86
, pp. 5817-5828
-
-
Ruscanu, S.1
Pascale, F.2
Bourge, M.3
-
48
-
-
33947134377
-
Autophagy-dependent viral recognition by plasmacytoid dendritic cells
-
DOI 10.1126/science.1136880
-
Lee HK, Lund JM, Ramanathan B, et al. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 2007;315:1398-1401. (Pubitemid 46399546)
-
(2007)
Science
, vol.315
, Issue.5817
, pp. 1398-1401
-
-
Lee, H.K.1
Lund, J.M.2
Ramanathan, B.3
Mizushima, N.4
Iwasaki, A.5
-
49
-
-
84865571191
-
TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification
-
OldenburgM, Kr ̈uger A, Ferstl R, et al. TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. Science 2012;337:1111-1115.
-
(2012)
Science
, vol.337
, pp. 1111-1115
-
-
Oldenburg, M.1
Kr ̈uger, A.2
Ferstl, R.3
-
50
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
DOI 10.1038/35047123
-
Hemmi H, Takeuchi O, Kawai T, et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000;408:740-745. (Pubitemid 32015992)
-
(2000)
Nature
, vol.408
, Issue.6813
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
51
-
-
74049121298
-
Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involvesmalarial hemozoin and host TLR9
-
Coban C, Igari Y, Yagi M, et al. Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involvesmalarial hemozoin and host TLR9. Cell HostMicrobe 2010;7:50-61.
-
(2010)
Cell HostMicrobe
, vol.7
, pp. 50-61
-
-
Coban, C.1
Igari, Y.2
Yagi, M.3
-
52
-
-
77952757782
-
Protein-DNA complex is the exclusive malaria parasite component that activates dendritic cells and triggers innate immune responses
-
Wu X, Gowda NM, Kumar S, Gowda DC. Protein-DNA complex is the exclusive malaria parasite component that activates dendritic cells and triggers innate immune responses. J Immunol 2010;184:4338-4348.
-
(2010)
J Immunol
, vol.184
, pp. 4338-4348
-
-
Wu, X.1
Gowda, N.M.2
Kumar, S.3
Gowda, D.C.4
-
53
-
-
79954570242
-
Granulin is a soluble cofactor for Toll-like receptor 9 signaling
-
Park B, Buti L, Lee S, et al. Granulin is a soluble cofactor for Toll-like receptor 9 signaling. Immunity 2011;34:1-15.
-
(2011)
Immunity
, vol.34
, pp. 1-15
-
-
Park, B.1
Buti, L.2
Lee, S.3
-
54
-
-
68849085894
-
A cell biological view of Toll-like receptor function: Regulation through compartmentalization
-
Barton GM, Kagan JC. A cell biological view of Toll-like receptor function: regulation through compartmentalization. Nat Rev Immunol 2009;9:535-542.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 535-542
-
-
Barton, G.M.1
Kagan, J.C.2
-
55
-
-
29244450802
-
Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
-
DOI 10.1038/ni1280, PII N1280
-
Barton GM, Kagan JC,Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol 2006;7:49-56. (Pubitemid 41823868)
-
(2006)
Nature Immunology
, vol.7
, Issue.1
, pp. 49-56
-
-
Barton, G.M.1
Kagan, J.C.2
Medzhitov, R.3
-
56
-
-
31344466165
-
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
-
DOI 10.1038/ni1297, PII N1297
-
Tabeta K, Hoebe K, Janssen EM, et al. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol 2006;7:156-164. (Pubitemid 43135881)
-
(2006)
Nature Immunology
, vol.7
, Issue.2
, pp. 156-164
-
-
Tabeta, K.1
Hoebe, K.2
Janssen, E.M.3
Du, X.4
Georgel, P.5
Crozat, K.6
Mudd, S.7
Mann, N.8
Sovath, S.9
Goode, J.10
Shamel, L.11
Herskovits, A.A.12
Portnoy, D.A.13
Cooke, M.14
Tarantino, L.M.15
Wiltshire, T.16
Steinberg, B.E.17
Grinstein, S.18
Beutler, B.19
-
57
-
-
40749098665
-
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
-
DOI 10.1038/nature06726, PII NATURE06726
-
Kim Y-M, Brinkmann MM, PaquetM-E, Ploegh HL. UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes. Nature 2008;452:234-238. (Pubitemid 351380247)
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 234-238
-
-
Kim, Y.-M.1
Brinkmann, M.M.2
Paquet, M.-E.3
Ploegh, H.L.4
-
58
-
-
33750016788
-
Herpes simplex virus encephalitis in human UNC-93B deficiency
-
DOI 10.1126/science.1128346
-
Casrouge A, Zhang S-Y, Eidenschenk C, et al.Herpes simplex virus encephalitis in humanUNC-93B deficiency. Science 2006;314:308-312. (Pubitemid 44571977)
-
(2006)
Science
, vol.314
, Issue.5797
, pp. 308-312
-
-
Casrouge, A.1
Zhang, S.-Y.2
Eidenschenk, C.3
Jouanguy, E.4
Puel, A.5
Yang, K.6
Alcais, A.7
Picard, C.8
Mahfoufi, N.9
Nicolas, N.10
Lorenzo, L.11
Plancoulaine, S.12
Senechal, B.13
Geissmann, F.14
Tabeta, K.15
Hoebe, K.16
Du, X.17
Miller, R.L.18
Heron, B.19
Mignot, C.20
Billette De Villemeur, T.21
Lebon, P.22
Dulac, O.23
Rozenberg, F.24
Beutler, B.25
Tardieu, M.26
Abel, L.27
Casanova, J.-L.28
more..
-
59
-
-
34247484007
-
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
-
DOI 10.1083/jcb.200612056
-
Brinkmann MM, Spooner E, Hoebe K, et al. The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling. J Cell Biol 2007;177:265-275. (Pubitemid 46658638)
-
(2007)
Journal of Cell Biology
, vol.177
, Issue.2
, pp. 265-275
-
-
Brinkmann, M.M.1
Spooner, E.2
Hoebe, K.3
Beutler, B.4
Ploegh, H.L.5
Kim, Y.-M.6
-
60
-
-
79960470158
-
Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking
-
Fukui R, Saitoh S-I, Kanno A, et al. Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking. Immunity 2011;35:69-81.
-
(2011)
Immunity
, vol.35
, pp. 69-81
-
-
Fukui, R.1
Saitoh, S.-I.2
Kanno, A.3
-
61
-
-
79960440600
-
Love triangle between Unc93B1, TLR7, and TLR9 prevents fatal attraction
-
Sasai M, Iwasaki A. Love triangle between Unc93B1, TLR7, and TLR9 prevents fatal attraction. Immunity 2011;35:3-5.
-
(2011)
Immunity
, vol.35
, pp. 3-5
-
-
Sasai, M.1
Iwasaki, A.2
-
62
-
-
84862804952
-
Accessorymolecules for Toll-like receptors and their function
-
Lee CC, Avalos AM, Ploegh HL. Accessorymolecules for Toll-like receptors and their function. Nat Rev Immunol 2012;12:168-179.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 168-179
-
-
Lee, C.C.1
Avalos, A.M.2
Ploegh, H.L.3
-
63
-
-
54949103603
-
A single basemutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors
-
Kiyokawa T, Akashi-Takamura S, Shibata T, et al. A single basemutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors. Int Immunol 2008;20:1407-1415.
-
(2008)
Int Immunol
, vol.20
, pp. 1407-1415
-
-
Kiyokawa, T.1
Akashi-Takamura, S.2
Shibata, T.3
-
64
-
-
77949940198
-
Intracellular Toll-like receptors
-
Blasius AL, Beutler B. Intracellular Toll-like receptors. Immunity 2010;32:305-315.
-
(2010)
Immunity
, vol.32
, pp. 305-315
-
-
Blasius, A.L.1
Beutler, B.2
-
65
-
-
57349191215
-
The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
-
Ewald SE, Lee BL, Lau L, et al. The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. Nature 2008;456:658-662.
-
(2008)
Nature
, vol.456
, pp. 658-662
-
-
Ewald, S.E.1
Lee, B.L.2
Lau, L.3
-
66
-
-
56349114913
-
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
-
Park B, Brinkmann MM, Spooner E, et al. Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9. Nat Immunol 2008;9:1407-1414.
-
(2008)
Nat Immunol
, vol.9
, pp. 1407-1414
-
-
Park, B.1
Brinkmann, M.M.2
Spooner, E.3
-
67
-
-
38849127573
-
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis
-
DOI 10.1126/science.1150110
-
AsagiriM, Hirai T, Kunigami T, et al. Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science 2008;319:624-627. (Pubitemid 351197065)
-
(2008)
Science
, vol.319
, Issue.5863
, pp. 624-627
-
-
Asagiri, M.1
Hirai, T.2
Kunigami, T.3
Kamano, S.4
Gober, H.-J.5
Okamoto, K.6
Nishikawa, K.7
Latz, E.8
Golenbock, D.T.9
Aoki, K.10
Ohya, K.11
Imai, Y.12
Morishita, Y.13
Miyazono, K.14
Kato, S.15
Saftig, P.16
Takayanagi, H.17
-
69
-
-
70449477746
-
Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells
-
Sepulveda FE, Maschalidi S, Colisson R, et al. Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells. Immunity 2009;31:737-748.
-
(2009)
Immunity
, vol.31
, pp. 737-748
-
-
Sepulveda, F.E.1
Maschalidi, S.2
Colisson, R.3
-
70
-
-
33644508366
-
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
-
DOI 10.1038/sj.emboj.7600991, PII 7600991
-
Husebye H, Halaas Ø, Stenmark H, et al. Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO J 2006;25:683-692. (Pubitemid 43292431)
-
(2006)
EMBO Journal
, vol.25
, Issue.4
, pp. 683-692
-
-
Husebye, H.1
Halaas, O.2
Stenmark, H.3
Tunheim, G.4
Sandanger, O.5
Bogen, B.6
Brech, A.7
Latz, E.8
Espevik, T.9
-
71
-
-
33646908228
-
Phosphoinositide-Mediated Adaptor Recruitment Controls Toll-like Receptor Signaling
-
DOI 10.1016/j.cell.2006.03.047, PII S0092867406005617
-
Kagan JC, Medzhitov R. Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 2006;125:943-955. (Pubitemid 43795199)
-
(2006)
Cell
, vol.125
, Issue.5
, pp. 943-955
-
-
Kagan, J.C.1
Medzhitov, R.2
-
72
-
-
33646567507
-
The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction
-
Rowe DC, McGettrick AF, Latz E, et al. The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction. Proc Natl Acad Sci USA 2006;103: 6299-6304.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6299-6304
-
-
Rowe, D.C.1
McGettrick, A.F.2
Latz, E.3
-
73
-
-
75449093273
-
TIR-containing adaptors in Toll-like receptor signalling
-
Jenkins KA, Mansell A. TIR-containing adaptors in Toll-like receptor signalling. Cytokine 2010;49:237-244.
-
(2010)
Cytokine
, vol.49
, pp. 237-244
-
-
Jenkins, K.A.1
Mansell, A.2
-
74
-
-
0032524335
-
MyD88, an adapter protein involved in interleukin-1 signaling
-
DOI 10.1074/jbc.273.20.12203
-
Burns K,Martinon F, Esslinger C, et al.MyD88, an adapter protein involved in interleukin-1 signaling. J Biol Chem 1998;273:12203-12209. (Pubitemid 28240584)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.20
, pp. 12203-12209
-
-
Burns, K.1
Martinon, F.2
Esslinger, C.3
Pahl, H.4
Schneider, P.5
Bodmer, J.-L.6
Di Marco, F.7
French, L.8
Tschopp, J.9
-
75
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
DOI 10.1126/science.1087262
-
Yamamoto M, Sato S, Hemmi H, et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 2003;301:640-643. (Pubitemid 36927946)
-
(2003)
Science
, vol.301
, Issue.5633
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
Akira, S.11
-
76
-
-
0037320451
-
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction
-
DOI 10.1038/ni886
-
OshiumiH,Matsumoto M, Funami K, et al. TICAM-1, an adaptor molecule that participates in Tolllike receptor 3-mediated interferon-beta induction. Nat Immunol 2003;4:161-167. (Pubitemid 36193018)
-
(2003)
Nature Immunology
, vol.4
, Issue.2
, pp. 161-167
-
-
Oshiumi, H.1
Matsumoto, M.2
Funami, K.3
Akazawa, T.4
Seya, T.5
-
77
-
-
0345991221
-
TIR-containing Adapter Molecule (TICAM)-2, a Bridging Adapter Recruiting to Toll-like Receptor 4 TICAM-1 That Induces Interferon-β
-
DOI 10.1074/jbc.M305820200
-
Oshiumi H, Sasai M, Shida K, et al. TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta. J Biol Chem 2003;278:49751-49762. (Pubitemid 37548808)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.50
, pp. 49751-49762
-
-
Oshiumi, H.1
Sasai, M.2
Shida, K.3
Fujita, T.4
Matsumoto, M.5
Seya, T.6
-
78
-
-
39149137198
-
Roles for LPS-dependent interaction and relocation of TLR4 and TRAMin TRIF-signaling
-
Tanimura N, Saitoh S, Matsumoto F, et al. Roles for LPS-dependent interaction and relocation of TLR4 and TRAMin TRIF-signaling. Biochem Biophys Res Commun 2008;368:693-699.
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 693-699
-
-
Tanimura, N.1
Saitoh, S.2
Matsumoto, F.3
-
79
-
-
0242624622
-
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
-
DOI 10.1038/ni986
-
Yamamoto M, Sato S, Hemmi H, et al. TRAM is specifically involved in the Toll-like receptor 4-mediatedMyD88-independent signaling pathway. Nat Immunol 2003;4:1144-1150. (Pubitemid 37428043)
-
(2003)
Nature Immunology
, vol.4
, Issue.11
, pp. 1144-1150
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Uematsu, S.4
Hoshino, K.5
Kaisho, T.6
Takeuchi, O.7
Takeda, K.8
Akira, S.9
-
80
-
-
33748871187
-
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
-
DOI 10.1038/ni1382, PII NI1382
-
Carty M, Goodbody R, Schroder M, et al. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat Immunol 2006;7:1074-1081. (Pubitemid 44420652)
-
(2006)
Nature Immunology
, vol.7
, Issue.10
, pp. 1074-1081
-
-
Carty, M.1
Goodbody, R.2
Schroder, M.3
Stack, J.4
Moynagh, P.N.5
Bowie, A.G.6
-
81
-
-
69449098052
-
The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis
-
Szretter KJ, Samuel MA, Gilfillan S, et al. The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis. J Virology 2009;83:9329-9338.
-
(2009)
J Virology
, vol.83
, pp. 9329-9338
-
-
Szretter, K.J.1
Samuel, M.A.2
Gilfillan, S.3
-
82
-
-
77953714711
-
Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
-
Lin S-C, Lo Y-C, Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature 2010;465:885-890.
-
(2010)
Nature
, vol.465
, pp. 885-890
-
-
Lin, S.-C.1
Lo, Y.-C.2
Wu, H.3
-
83
-
-
33747615237
-
Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
-
DOI 10.1038/ni1367, PII NI1367
-
Yamamoto M, Okamoto T, Takeda K, et al. Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling. Nat Immunol 2006;7:962-970. (Pubitemid 44263910)
-
(2006)
Nature Immunology
, vol.7
, Issue.9
, pp. 962-970
-
-
Yamamoto, M.1
Okamoto, T.2
Takeda, K.3
Sato, S.4
Sanjo, H.5
Uematsu, S.6
Saitoh, T.7
Yamamoto, N.8
Sakurai, H.9
Ishii, K.J.10
Yamaoka, S.11
Kawai, T.12
Matsuura, Y.13
Takeuchi, O.14
Akira, S.15
-
84
-
-
63649116570
-
Ubiquitylation in innate and adaptive immunity
-
Bhoj VG, Chen ZJ. Ubiquitylation in innate and adaptive immunity. Nature 2009;458:430-437.
-
(2009)
Nature
, vol.458
, pp. 430-437
-
-
Bhoj, V.G.1
Chen, Z.J.2
-
85
-
-
3142581432
-
Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IκBζ
-
DOI 10.1038/nature02738
-
Yamamoto M, Yamazaki S, Uematsu S, et al. Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta. Nature 2004;430:218-222. (Pubitemid 38902431)
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 218-222
-
-
Yamamoto, M.1
Yamazaki, S.2
Uematsu, S.3
Sato, S.4
Hemmmi, H.5
Hoshino, K.6
Kaisho, T.7
Kuwata, H.8
Takeuchi, O.9
Takeshige, K.10
Saitoh, T.11
Yamaoka, S.12
Yamamoto, N.13
Yamamoto, S.14
Muta, T.15
Takeda, K.16
Akira, S.17
-
86
-
-
45549090987
-
Class-specific regulation of pro-inflammatory genes byMyD88 pathways and IkappaBzeta
-
Kayama H, Ramirez-Carrozzi VR, YamamotoM, et al. Class-specific regulation of pro-inflammatory genes byMyD88 pathways and IkappaBzeta. J Biol Chem 2008;283:12468-12477.
-
(2008)
J Biol Chem
, vol.283
, pp. 12468-12477
-
-
Kayama, H.1
Ramirez-Carrozzi, V.R.2
Yamamoto, M.3
-
87
-
-
62849092708
-
Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals
-
Litvak V, Ramsey SA, RustAG, et al. Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals. Nat Immunol 2009;10:437-443.
-
(2009)
Nat Immunol
, vol.10
, pp. 437-443
-
-
Litvak, V.1
Ramsey, S.A.2
Rust, A.G.3
-
88
-
-
33846064294
-
Innate immune functions of plasmacytoid dendritic cells
-
DOI 10.1016/j.coi.2006.11.004, PII S0952791506002366, Innate immunity/Antigen processing and recognition
-
Cao W, Liu Y-J. Innate immune functions of plasmacytoid dendritic cells. Curr Opin Immunol 2007;19:24-30. (Pubitemid 46073695)
-
(2007)
Current Opinion in Immunology
, vol.19
, Issue.1
, pp. 24-30
-
-
Cao, W.1
Liu, Y.-J.2
-
89
-
-
5444274514
-
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
-
DOI 10.1038/ni1118
-
Kawai T, Sato S, Ishii KJ, et al. Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 withMyD88 and TRAF6. Nat Immunol 2004;5:1061-1068. (Pubitemid 41057726)
-
(2004)
Nature Immunology
, vol.5
, Issue.10
, pp. 1061-1068
-
-
Kawai, T.1
Sato, S.2
Ishii, K.J.3
Coban, C.4
Hemmi, H.5
Yamamoto, M.6
Terai, K.7
Matsuda, M.8
Inoue, J.-I.9
Uematsu, S.10
Takeuchi, O.11
Akira, S.12
-
90
-
-
33645963170
-
Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells
-
ShinoharaML, Lu L, Bu J, et al. Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol 2006;7:498-506.
-
(2006)
Nat Immunol
, vol.7
, pp. 498-506
-
-
Shinohara, M.L.1
Lu, L.2
Bu, J.3
-
91
-
-
52549127241
-
Toll-like receptor-mediated induction of type i interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
-
Cao W, Manicassamy S, Tang H, et al. Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. Nat Immunol 2008;9:1157-1164.
-
(2008)
Nat Immunol
, vol.9
, pp. 1157-1164
-
-
Cao, W.1
Manicassamy, S.2
Tang, H.3
-
92
-
-
42649114059
-
The IRF family transcription factors in immunity and oncogenesis
-
DOI 10.1146/annurev.immunol.26.021607.090400
-
Tamura T, Yanai H, Savitsky D, Taniguchi T. The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol 2008;26:535-584. (Pubitemid 351600385)
-
(2008)
Annual Review of Immunology
, vol.26
, pp. 535-584
-
-
Tamura, T.1
Yanai, H.2
Savitsky, D.3
Taniguchi, T.4
-
93
-
-
15044345461
-
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
-
DOI 10.1038/nature03308
-
Takaoka A, Yanai H, Kondo S, et al. Integral role of IRF-5 in the gene induction programmeactivated by Toll-like receptors. Nature 2005;434:243-249. (Pubitemid 40388058)
-
(2005)
Nature
, vol.434
, Issue.7030
, pp. 243-249
-
-
Takaoka, A.1
Yanai, H.2
Kondo, S.3
Duncan, G.4
Negishi, H.5
Mizutani, T.6
Kano, S.-I.7
Honda, K.8
Ohba, Y.9
Mak, T.W.10
Taniguchi, T.11
-
94
-
-
27644548945
-
Negative regulation of Toll-like-receptor signaling by IRF-4
-
DOI 10.1073/pnas.0508327102
-
Negishi H, Ohba Y, Yanai H, et al. Negative regulation of Toll-like-receptor signaling by IRF-4. Proc Natl Acad Sci USA 2005;102:15989-15994. (Pubitemid 41552855)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.44
, pp. 15989-15994
-
-
Negishi, H.1
Ohba, Y.2
Yanai, H.3
Takaoka, A.4
Honma, K.5
Yui, K.6
Matsuyama, T.7
Taniguchi, T.8
Honda, K.9
-
95
-
-
50149089360
-
Thefunction of TRADDin signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors
-
Pobezinskaya YL, Kim Y-S,Choksi S, et al.Thefunction of TRADDin signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors. Nat Immunol 2008;9:1047-1054.
-
(2008)
Nat Immunol
, vol.9
, pp. 1047-1054
-
-
Pobezinskaya, Y.L.1
Kim, Y.-S.2
Choksi, S.3
-
96
-
-
2442689141
-
Toll-like receptor 9 signaling activates NF-κB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells
-
Tsujimura H, Tamura T, Kong HJ, et al. Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells. J Immunol 2004;172:6820-6827. (Pubitemid 38669120)
-
(2004)
Journal of Immunology
, vol.172
, Issue.11
, pp. 6820-6827
-
-
Tsujimura, H.1
Tamura, T.2
Kong, H.J.3
Nishiyama, A.4
Ishii, K.J.5
Klinman, D.M.6
Ozato, K.7
-
97
-
-
39049183044
-
Regulation and function of IKKand IKK-related kinases
-
ḦackerH,KarinM.Regulation and function of IKKand IKK-related kinases. Sci STKE2006;357:re13.
-
(2006)
Sci STKE
, vol.357
-
-
Ḧacker, H.1
Karin, M.2
-
98
-
-
50049125047
-
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
-
Ermolaeva MA, Michallet M-C, Papadopoulou N, et al. Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nat Immunol 2008;9:1037-1046.
-
(2008)
Nat Immunol
, vol.9
, pp. 1037-1046
-
-
Ermolaeva, M.A.1
Michallet, M.-C.2
Papadopoulou, N.3
-
99
-
-
58149240784
-
ThePellino family: IRAK E3 ligases with emerging roles in innate immune signalling
-
Moynagh PN.ThePellino family: IRAK E3 ligases with emerging roles in innate immune signalling. Trends Immunol 2009;1:33-142.
-
(2009)
Trends Immunol
, vol.1
, pp. 33-142
-
-
Moynagh, P.N.1
-
100
-
-
84864083448
-
Pellino 2 is critical for Toll-like receptor/interleukin-1 receptor (TLR/IL-1R)-mediated post-transcriptional control
-
Kim TW, Yu M, Zhou H, et al. Pellino 2 is critical for Toll-like receptor/interleukin-1 receptor (TLR/IL-1R)-mediated post-transcriptional control. J Biol Chem 2012;30:25686-25695.
-
(2012)
J Biol Chem
, vol.30
, pp. 25686-25695
-
-
Kim, T.W.1
Yu, M.2
Zhou, H.3
-
101
-
-
84867744278
-
Pellino3 targets the IRF7 pathway and facilitates auto-regulation of TLR3-and viral-induced expression of type i interferons
-
Siednienko J, Jackson R, Mellett M, et al. Pellino3 targets the IRF7 pathway and facilitates auto-regulation of TLR3-and viral-induced expression of type I interferons. Nat Immunol 2012;11:1055-1062.
-
(2012)
Nat Immunol
, vol.11
, pp. 1055-1062
-
-
Siednienko, J.1
Jackson, R.2
Mellett, M.3
-
102
-
-
30544451546
-
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
-
DOI 10.1038/nature04369, PII NATURE04369
-
Ḧacker H, Redecke V, Blagoev B, et al. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 2006;439:204-207. (Pubitemid 43083141)
-
(2006)
Nature
, vol.439
, Issue.7073
, pp. 204-207
-
-
Hacker, H.1
Redecke, V.2
Blagoev, B.3
Kratchmarova, I.4
Hsu, L.-C.5
Wang, G.G.6
Kamps, M.P.7
Raz, E.8
Wagner, H.9
Hacker, G.10
Mann, M.11
Karin, M.12
-
103
-
-
30544447047
-
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
-
DOI 10.1038/nature04374, PII NATURE04374
-
Oganesyan G, Saha SK, Guo B, et al. Critical role of TRAF3 in the Toll-like receptor-dependent and-independent antiviral response. Nature 2006;439:208-211. (Pubitemid 43083142)
-
(2006)
Nature
, vol.439
, Issue.7073
, pp. 208-211
-
-
Oganesyan, G.1
Saha, S.K.2
Guo, B.3
He, J.Q.4
Shahangian, A.5
Zarnegar, B.6
Perry, A.7
Cheng, G.8
-
104
-
-
74049136127
-
Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type i interferons and proinflammatory cytokines
-
Tseng P-H,MatsuzawaA, ZhangW, et al. Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines. Nat Immunol 2010;11:70-75.
-
(2010)
Nat Immunol
, vol.11
, pp. 70-75
-
-
Tseng, P.-H.1
Matsuzawa, A.2
Zhang, W.3
-
105
-
-
79960657903
-
Negative regulation of signaling by a soluble formof toll-like receptor 9
-
Chockalingam A, Cameron JL, Brooks JC, Leifer CA. Negative regulation of signaling by a soluble formof toll-like receptor 9. Eur J Immunol 2011;41:2176-2184.
-
(2011)
Eur J Immunol
, vol.41
, pp. 2176-2184
-
-
Chockalingam, A.1
Cameron, J.L.2
Brooks, J.C.3
Leifer, C.A.4
-
106
-
-
34247175428
-
The Toll-Interleukin-1 Receptor Member SIGIRR Regulates Colonic Epithelial Homeostasis, Inflammation, and Tumorigenesis
-
DOI 10.1016/j.immuni.2007.02.012, PII S1074761307002063
-
Xiao H, Gulen MF, Qin J, et al. The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis. Immunity 2007;26:461-475. (Pubitemid 46602997)
-
(2007)
Immunity
, vol.26
, Issue.4
, pp. 461-475
-
-
Xiao, H.1
Gulen, M.F.2
Qin, J.3
Yao, J.4
Bulek, K.5
Kish, D.6
Altuntas, C.Z.7
Wald, D.8
Ma, C.9
Zhou, H.10
Tuohy, V.K.11
Fairchild, R.L.12
De La Motte, C.13
Cua, D.14
Vallance, B.A.15
Li, X.16
-
107
-
-
21644477461
-
SIGIRR inhibits interleukin-1 receptor- and Toll-like receptor 4-mediated signaling through different mechanisms
-
DOI 10.1074/jbc.M501363200
-
Qin J, Qian Y, Yao J, et al. SIGIRR inhibits interleukin-1 receptor-and toll-like receptor 4-mediated signaling through different mechanisms. J Biol Chem 2005;280:25233-25241. (Pubitemid 40934617)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.26
, pp. 25233-25241
-
-
Qin, J.1
Qian, Y.2
Yao, J.3
Grace, C.4
Li, X.5
-
108
-
-
77954750715
-
ST2 negatively regulates TLR2 signaling, but is not required for bacterial lipoprotein-induced tolerance
-
Liu J, Buckley JM, Redmond HP, Wang JH. ST2 negatively regulates TLR2 signaling, but is not required for bacterial lipoprotein-induced tolerance. J Immunol 2010;184:5802-5808.
-
(2010)
J Immunol
, vol.184
, pp. 5802-5808
-
-
Liu, J.1
Buckley, J.M.2
Redmond, H.P.3
Wang, J.H.4
-
109
-
-
2442643942
-
Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors
-
DOI 10.1038/ni1066
-
Chuang T-H, Ulevitch RJ. Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors.Nat Immunol 2004;5:495-502. (Pubitemid 38660461)
-
(2004)
Nature Immunology
, vol.5
, Issue.5
, pp. 495-502
-
-
Chuang, T.-H.1
Ulevitch, R.J.2
-
110
-
-
0037454946
-
Inhibition of interleukin 1 receptor/toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
-
DOI 10.1084/jem.20021790
-
BurnsK, Janssens S,BrissoniB, et al. Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J Exp Med 2003;197:263-268. (Pubitemid 36152320)
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.2
, pp. 263-268
-
-
Burns, K.1
Janssens, S.2
Brissoni, B.3
Olivos, N.4
Beyaert, R.5
Tschopp, J.6
-
111
-
-
67349092199
-
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway
-
Palsson-McDermott EM, Doyle SL, McGettrick AF, et al. TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nat Immunol 2009;10:579-586.
-
(2009)
Nat Immunol
, vol.10
, pp. 579-586
-
-
Palsson-Mcdermott, E.M.1
Doyle, S.L.2
McGettrick, A.F.3
-
112
-
-
84857726793
-
The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation
-
Doyle SL, Husebye H, Connolly DJ, et al. The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nat Commun 2012;3:707.
-
(2012)
Nat Commun
, vol.3
, pp. 707
-
-
Doyle, S.L.1
Husebye, H.2
Connolly, D.J.3
-
113
-
-
70349324347
-
MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3
-
Kenny EF, Talbot S, Gong M, et al. MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3. J Immunol 2009;183:3642-3651.
-
(2009)
J Immunol
, vol.183
, pp. 3642-3651
-
-
Kenny, E.F.1
Talbot, S.2
Gong, M.3
-
114
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
DOI 10.1016/S0092-8674(02)00827-9
-
Kobayashi K, Hernandez LD, Gaĺan JE, et al. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 2002;110:191-202. (Pubitemid 34876547)
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway Jr., C.A.4
Medzhitov, R.5
Flavell, R.A.6
-
115
-
-
77954695244
-
SMAD4 is required for development of maximal endotoxin tolerance
-
Pan H, Ding E, HuM, et al. SMAD4 is required for development of maximal endotoxin tolerance. J Immunol 2010;184:5502-5509.
-
(2010)
J Immunol
, vol.184
, pp. 5502-5509
-
-
Pan, H.1
Ding, E.2
Hu, M.3
-
116
-
-
77951931275
-
Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production
-
Gabhann JN, Higgs R, Brennan K, et al. Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production. J Immunol 2010;184:2314-2320.
-
(2010)
J Immunol
, vol.184
, pp. 2314-2320
-
-
Gabhann, J.N.1
Higgs, R.2
Brennan, K.3
-
117
-
-
22544451204
-
A novel splice variant of interleukin-1 receptor (IL-1R)-Associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling
-
DOI 10.1128/MCB.25.15.6521-6532.2005
-
Rao N, Nguyen S, Ngo K, Fung-LeungW-P. A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling. Mol Cell Biol 2005;25:6521-6532. (Pubitemid 41023227)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.15
, pp. 6521-6532
-
-
Rao, N.1
Nguyen, S.2
Ngo, K.3
Fung-Leung, W.-P.4
-
118
-
-
5444223519
-
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
-
DOI 10.1038/ni1110
-
BooneDL, Turer EE, Lee EG, et al.The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat Immunol 2004;5:1052-1060. (Pubitemid 41057725)
-
(2004)
Nature Immunology
, vol.5
, Issue.10
, pp. 1052-1060
-
-
Boone, D.L.1
Turer, E.E.2
Lee, E.G.3
Ahmad, R.-C.4
Wheeler, M.T.5
Tsui, C.6
Hurley, P.7
Chien, M.8
Chai, S.9
Hitotsumatsu, O.10
McNally, E.11
Pickart, C.12
Ma, A.13
-
119
-
-
33846984613
-
LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-κB activation
-
DOI 10.1074/jbc.M607481200
-
Wullaert A, Verstrepen L, Van Huffel S, et al. LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activation. J Biol Chem 2007;282:81-90. (Pubitemid 47076640)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.1
, pp. 81-90
-
-
Wullaert, A.1
Verstrepen, L.2
Van Huffel, S.3
Adib-Conquy, M.4
Cornelis, S.5
Kreike, M.6
Haegman, M.7
El Bakkouri, K.8
Sanders, M.9
Verhelst, K.10
Carpentier, I.11
Cavaillon, J.-M.12
Heyninck, K.13
Beyaert, R.14
-
120
-
-
34249058290
-
Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK
-
DOI 10.1074/jbc.M700017200
-
Guo B, Cheng G.Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK. J Biol Chem 2007;282:11817-11826. (Pubitemid 47100710)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.16
, pp. 11817-11826
-
-
Guo, B.1
Cheng, G.2
-
121
-
-
69049086481
-
TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
-
Kawagoe T, Takeuchi O, Takabatake Y, et al. TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis. Nat Immunol 2009;10:965-972.
-
(2009)
Nat Immunol
, vol.10
, pp. 965-972
-
-
Kawagoe, T.1
Takeuchi, O.2
Takabatake, Y.3
-
122
-
-
79959329537
-
NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK
-
Xia X, Cui J,Wang HY, et al. NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK. Immunity 2011;34:843-853.
-
(2011)
Immunity
, vol.34
, pp. 843-853
-
-
Xia, X.1
Cui, J.2
Wang, H.Y.3
-
123
-
-
28844460239
-
The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 and TRAF7
-
DOI 10.1074/jbc.M509526200
-
Yoshida H, Jono H, Kai H, Li J-D. The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling vianegative cross-talkwithTRAF6 andTRAF7. JBiolChem 2005;280:41111-41121. (Pubitemid 41780606)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.49
, pp. 41111-41121
-
-
Yoshida, H.1
Jono, H.2
Kai, H.3
Li, J.-D.4
-
124
-
-
84863229333
-
E3 ubiquitin ligase tripartite motif 38 negatively regulates TLRmediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages
-
Zhao W, Wang L, Zhang M, et al. E3 ubiquitin ligase tripartite motif 38 negatively regulates TLRmediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages. J Immunol 2012;188:2567-2574.
-
(2012)
J Immunol
, vol.188
, pp. 2567-2574
-
-
Zhao, W.1
Wang, L.2
Zhang, M.3
-
125
-
-
10844219793
-
Cutting edge: NF-κB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation
-
Sasai M, Oshiumi H, Matsumoto M, et al. Cutting edge: NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation. J Immunol 2005;174:27-30. (Pubitemid 40007387)
-
(2005)
Journal of Immunology
, vol.174
, Issue.1
, pp. 27-30
-
-
Sasai, M.1
Oshiumi, H.2
Matsumoto, M.3
Inoue, N.4
Fujita, F.5
Nakanishi, M.6
Seya, T.7
-
126
-
-
84862102052
-
Tripartite motif-containing protein 38 negatively regulates TLR3/4-and RIG-I-mediated IFN-β production and antiviral response by targeting NAP1
-
Zhao W, Wang L, Zhang M, et al. Tripartite motif-containing protein 38 negatively regulates TLR3/4-and RIG-I-mediated IFN-β production and antiviral response by targeting NAP1. J Immunol 2012;188:5311-5318.
-
(2012)
J Immunol
, vol.188
, pp. 5311-5318
-
-
Zhao, W.1
Wang, L.2
Zhang, M.3
-
127
-
-
79951818786
-
NF-κB1 inhibits TLR-induced IFN-β production in macrophages through TPL-2-dependent ERK activation
-
Yang H-T, Wang Y, Zhao X, et al. NF-κB1 inhibits TLR-induced IFN-β production in macrophages through TPL-2-dependent ERK activation. J Immunol 2011;186:1989-1996.
-
(2011)
J Immunol
, vol.186
, pp. 1989-1996
-
-
Yang, H.-T.1
Wang, Y.2
Zhao, X.3
-
128
-
-
69549129472
-
TPL-2 negatively regulates interferon-beta production inmacrophages andmyeloid dendritic cells
-
Kaiser F, Cook D, Papoutsopoulou S, et al. TPL-2 negatively regulates interferon-beta production inmacrophages andmyeloid dendritic cells. J ExpMed 2009;206:1863-1871.
-
(2009)
J ExpMed
, vol.206
, pp. 1863-1871
-
-
Kaiser, F.1
Cook, D.2
Papoutsopoulou, S.3
-
129
-
-
14844344042
-
The nuclear IκB protein IκBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria
-
Hirotani T, Lee PY, Kuwata H, et al. The nuclear IkappaB protein IkappaBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria. J Immunol 2005;174:3650-3657. (Pubitemid 40354075)
-
(2005)
Journal of Immunology
, vol.174
, Issue.6
, pp. 3650-3657
-
-
Hirotani, T.1
Lee, P.Y.2
Kuwata, H.3
Yamamoto, M.4
Matsumoto, M.5
Kawase, I.6
Akira, S.7
Takeda, K.8
-
130
-
-
30444456370
-
IκBNS inhibits induction of a subset of toll-like receptor-dependent genes and limits inflammation
-
DOI 10.1016/j.immuni.2005.11.004, PII S1074761305003778
-
Kuwata H, Matsumoto M, Atarashi K, et al. IkappaBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation. Immunity 2006;24:41-51. (Pubitemid 43077199)
-
(2006)
Immunity
, vol.24
, Issue.1
, pp. 41-51
-
-
Kuwata, H.1
Matsumoto, M.2
Atarashi, K.3
Morishita, H.4
Hirotani, T.5
Koga, R.6
Takeda, K.7
-
131
-
-
33646547951
-
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4
-
GilchristM,Thorsson V, Li B, et al. Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4. Nature 2006;441:173-178.
-
(2006)
Nature
, vol.441
, pp. 173-178
-
-
Gilchrist, M.1
Thorsson, V.2
Li, B.3
-
132
-
-
67349167059
-
Zc3h12a is anRNase essential for controllingimmune responses by regulatingmRNA decay
-
Matsushita K, Takeuchi O, StandleyDM,et al. Zc3h12a is anRNase essential for controllingimmune responses by regulatingmRNA decay. Nature 2009;458:1185-1190.
-
(2009)
Nature
, vol.458
, pp. 1185-1190
-
-
Matsushita, K.1
Takeuchi, O.2
Standley, D.M.3
-
133
-
-
8544255551
-
The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis
-
DOI 10.1186/ar1441
-
Carrick DM, Lai WS, Blackshear PJ. The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokinemRNA turnover and arthritis. Arthritis ResTher 2004;4:248-264. (Pubitemid 39490013)
-
(2004)
Arthritis Research and Therapy
, vol.6
, Issue.6
, pp. 248-264
-
-
Carrick, D.M.1
Lai, W.S.2
Blackshear, P.J.3
|