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Volumn 35, Issue 1, 2011, Pages 69-81

Unc93B1 restricts systemic lethal inflammation by orchestrating toll-like receptor 7 and 9 trafficking

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; GAMMA INTERFERON; INTERLEUKIN 17; PEPTIDES AND PROTEINS; PROTEIN UNC93B1; SMOOTH MUSCLE ANTIBODY; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

EID: 79960470158     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2011.05.010     Document Type: Article
Times cited : (182)

References (52)
  • 3
    • 33748447541 scopus 로고    scopus 로고
    • Type I interferon in systemic lupus erythematosus and other autoimmune diseases
    • Banchereau J., Pascual V. Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 2006, 25:383-392.
    • (2006) Immunity , vol.25 , pp. 383-392
    • Banchereau, J.1    Pascual, V.2
  • 4
    • 26844467349 scopus 로고    scopus 로고
    • Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
    • Barrat F.J., Meeker T., Gregorio J., Chan J.H., Uematsu S., Akira S., Chang B., Duramad O., Coffman R.L. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. J. Exp. Med. 2005, 202:1131-1139.
    • (2005) J. Exp. Med. , vol.202 , pp. 1131-1139
    • Barrat, F.J.1    Meeker, T.2    Gregorio, J.3    Chan, J.H.4    Uematsu, S.5    Akira, S.6    Chang, B.7    Duramad, O.8    Coffman, R.L.9
  • 5
    • 29244450802 scopus 로고    scopus 로고
    • Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
    • Barton G.M., Kagan J.C., Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat. Immunol. 2006, 7:49-56.
    • (2006) Nat. Immunol. , vol.7 , pp. 49-56
    • Barton, G.M.1    Kagan, J.C.2    Medzhitov, R.3
  • 6
    • 58449124804 scopus 로고    scopus 로고
    • The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
    • Bauquet A.T., Jin H., Paterson A.M., Mitsdoerffer M., Ho I.C., Sharpe A.H., Kuchroo V.K. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat. Immunol. 2009, 10:167-175.
    • (2009) Nat. Immunol. , vol.10 , pp. 167-175
    • Bauquet, A.T.1    Jin, H.2    Paterson, A.M.3    Mitsdoerffer, M.4    Ho, I.C.5    Sharpe, A.H.6    Kuchroo, V.K.7
  • 7
    • 77949940198 scopus 로고    scopus 로고
    • Intracellular toll-like receptors
    • Blasius A.L., Beutler B. Intracellular toll-like receptors. Immunity 2010, 32:305-315.
    • (2010) Immunity , vol.32 , pp. 305-315
    • Blasius, A.L.1    Beutler, B.2
  • 8
    • 34247484007 scopus 로고    scopus 로고
    • The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
    • Brinkmann M.M., Spooner E., Hoebe K., Beutler B., Ploegh H.L., Kim Y.M. The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling. J. Cell Biol. 2007, 177:265-275.
    • (2007) J. Cell Biol. , vol.177 , pp. 265-275
    • Brinkmann, M.M.1    Spooner, E.2    Hoebe, K.3    Beutler, B.4    Ploegh, H.L.5    Kim, Y.M.6
  • 11
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • Chan O.T., Hannum L.G., Haberman A.M., Madaio M.P., Shlomchik M.J. A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J. Exp. Med. 1999, 189:1639-1648.
    • (1999) J. Exp. Med. , vol.189 , pp. 1639-1648
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3    Madaio, M.P.4    Shlomchik, M.J.5
  • 12
    • 0033214474 scopus 로고    scopus 로고
    • B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity
    • Chan O.T., Madaio M.P., Shlomchik M.J. B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity. J. Immunol. 1999, 163:3592-3596.
    • (1999) J. Immunol. , vol.163 , pp. 3592-3596
    • Chan, O.T.1    Madaio, M.P.2    Shlomchik, M.J.3
  • 13
    • 33748472865 scopus 로고    scopus 로고
    • Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
    • Christensen S.R., Shupe J., Nickerson K., Kashgarian M., Flavell R.A., Shlomchik M.J. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 2006, 25:417-428.
    • (2006) Immunity , vol.25 , pp. 417-428
    • Christensen, S.R.1    Shupe, J.2    Nickerson, K.3    Kashgarian, M.4    Flavell, R.A.5    Shlomchik, M.J.6
  • 14
    • 36048962438 scopus 로고    scopus 로고
    • Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
    • Deane J.A., Pisitkun P., Barrett R.S., Feigenbaum L., Town T., Ward J.M., Flavell R.A., Bolland S. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 2007, 27:801-810.
    • (2007) Immunity , vol.27 , pp. 801-810
    • Deane, J.A.1    Pisitkun, P.2    Barrett, R.S.3    Feigenbaum, L.4    Town, T.5    Ward, J.M.6    Flavell, R.A.7    Bolland, S.8
  • 16
    • 0033038486 scopus 로고    scopus 로고
    • Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis
    • Deng G.M., Nilsson I.M., Verdrengh M., Collins L.V., Tarkowski A. Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis. Nat. Med. 1999, 5:702-705.
    • (1999) Nat. Med. , vol.5 , pp. 702-705
    • Deng, G.M.1    Nilsson, I.M.2    Verdrengh, M.3    Collins, L.V.4    Tarkowski, A.5
  • 17
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • Diebold S.S., Kaisho T., Hemmi H., Akira S., Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004, 303:1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis e Sousa, C.5
  • 19
    • 33646362290 scopus 로고    scopus 로고
    • B-cell targeting in rheumatoid arthritis and other autoimmune diseases
    • Edwards J.C., Cambridge G. B-cell targeting in rheumatoid arthritis and other autoimmune diseases. Nat. Rev. Immunol. 2006, 6:394-403.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 394-403
    • Edwards, J.C.1    Cambridge, G.2
  • 20
    • 33645076274 scopus 로고    scopus 로고
    • TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE
    • Ehlers M., Fukuyama H., McGaha T.L., Aderem A., Ravetch J.V. TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE. J. Exp. Med. 2006, 203:553-561.
    • (2006) J. Exp. Med. , vol.203 , pp. 553-561
    • Ehlers, M.1    Fukuyama, H.2    McGaha, T.L.3    Aderem, A.4    Ravetch, J.V.5
  • 21
    • 67449136127 scopus 로고    scopus 로고
    • Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
    • Fukui R., Saitoh S., Matsumoto F., Kozuka-Hata H., Oyama M., Tabeta K., Beutler B., Miyake K. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing. J. Exp. Med. 2009, 206:1339-1350.
    • (2009) J. Exp. Med. , vol.206 , pp. 1339-1350
    • Fukui, R.1    Saitoh, S.2    Matsumoto, F.3    Kozuka-Hata, H.4    Oyama, M.5    Tabeta, K.6    Beutler, B.7    Miyake, K.8
  • 25
    • 34547691044 scopus 로고    scopus 로고
    • Hemophagocytic syndromes
    • Janka G.E. Hemophagocytic syndromes. Blood Rev. 2007, 21:245-253.
    • (2007) Blood Rev. , vol.21 , pp. 245-253
    • Janka, G.E.1
  • 26
    • 3242752040 scopus 로고    scopus 로고
    • An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder
    • Jordan M.B., Hildeman D., Kappler J., Marrack P. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood 2004, 104:735-743.
    • (2004) Blood , vol.104 , pp. 735-743
    • Jordan, M.B.1    Hildeman, D.2    Kappler, J.3    Marrack, P.4
  • 27
    • 33646147362 scopus 로고    scopus 로고
    • Toll-like receptor function and signaling
    • quiz 988
    • Kaisho T., Akira S. Toll-like receptor function and signaling. J. Allergy Clin. Immunol. 2006, 117:979-987. quiz 988.
    • (2006) J. Allergy Clin. Immunol. , vol.117 , pp. 979-987
    • Kaisho, T.1    Akira, S.2
  • 29
    • 40749098665 scopus 로고    scopus 로고
    • UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
    • Kim Y.M., Brinkmann M.M., Paquet M.E., Ploegh H.L. UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes. Nature 2008, 452:234-238.
    • (2008) Nature , vol.452 , pp. 234-238
    • Kim, Y.M.1    Brinkmann, M.M.2    Paquet, M.E.3    Ploegh, H.L.4
  • 30
    • 0025852445 scopus 로고
    • A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
    • Kitamura D., Roes J., Kühn R., Rajewsky K. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature 1991, 350:423-426.
    • (1991) Nature , vol.350 , pp. 423-426
    • Kitamura, D.1    Roes, J.2    Kühn, R.3    Rajewsky, K.4
  • 31
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg A.M. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 2002, 20:709-760.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 32
    • 33646776086 scopus 로고    scopus 로고
    • Peripheral hemophagocytosis: An early indicator of advanced systemic inflammatory response syndrome/hemophagocytic syndrome
    • Kuwata K., Yamada S., Kinuwaki E., Naito M., Mitsuya H. Peripheral hemophagocytosis: An early indicator of advanced systemic inflammatory response syndrome/hemophagocytic syndrome. Shock 2006, 25:344-350.
    • (2006) Shock , vol.25 , pp. 344-350
    • Kuwata, K.1    Yamada, S.2    Kinuwaki, E.3    Naito, M.4    Mitsuya, H.5
  • 35
    • 34247891509 scopus 로고    scopus 로고
    • Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease
    • Marshak-Rothstein A., Rifkin I.R. Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease. Annu. Rev. Immunol. 2007, 25:419-441.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 419-441
    • Marshak-Rothstein, A.1    Rifkin, I.R.2
  • 36
    • 33947629255 scopus 로고    scopus 로고
    • Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
    • Miyake K. Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin. Immunol. 2007, 19:3-10.
    • (2007) Semin. Immunol. , vol.19 , pp. 3-10
    • Miyake, K.1
  • 37
    • 0032924316 scopus 로고    scopus 로고
    • Deranged blood coagulation equilibrium as a factor of massive liver necrosis following endotoxin administration in partially hepatectomized rats
    • Mochida S., Arai M., Ohno A., Yamanobe F., Ishikawa K., Matsui A., Maruyama I., Kato H., Fujiwara K. Deranged blood coagulation equilibrium as a factor of massive liver necrosis following endotoxin administration in partially hepatectomized rats. Hepatology 1999, 29:1532-1540.
    • (1999) Hepatology , vol.29 , pp. 1532-1540
    • Mochida, S.1    Arai, M.2    Ohno, A.3    Yamanobe, F.4    Ishikawa, K.5    Matsui, A.6    Maruyama, I.7    Kato, H.8    Fujiwara, K.9
  • 38
  • 39
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H., Miyazaki J., Smith A.G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat. Genet. 2000, 24:372-376.
    • (2000) Nat. Genet. , vol.24 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 40
    • 70350515662 scopus 로고    scopus 로고
    • The follicular versus marginal zone B lymphocyte cell fate decision
    • Pillai S., Cariappa A. The follicular versus marginal zone B lymphocyte cell fate decision. Nat. Rev. Immunol. 2009, 9:767-777.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 767-777
    • Pillai, S.1    Cariappa, A.2
  • 42
    • 77950490375 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists
    • Rajagopal D., Paturel C., Morel Y., Uematsu S., Akira S., Diebold S.S. Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists. Blood 2010, 115:1949-1957.
    • (2010) Blood , vol.115 , pp. 1949-1957
    • Rajagopal, D.1    Paturel, C.2    Morel, Y.3    Uematsu, S.4    Akira, S.5    Diebold, S.S.6
  • 44
    • 0031577470 scopus 로고    scopus 로고
    • A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission
    • Sakai K., Miyazaki J. A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission. Biochem. Biophys. Res. Commun. 1997, 237:318-324.
    • (1997) Biochem. Biophys. Res. Commun. , vol.237 , pp. 318-324
    • Sakai, K.1    Miyazaki, J.2
  • 47
    • 78650108453 scopus 로고    scopus 로고
    • Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage
    • Teichmann L.L., Ols M.L., Kashgarian M., Reizis B., Kaplan D.H., Shlomchik M.J. Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage. Immunity 2010, 33:967-978.
    • (2010) Immunity , vol.33 , pp. 967-978
    • Teichmann, L.L.1    Ols, M.L.2    Kashgarian, M.3    Reizis, B.4    Kaplan, D.H.5    Shlomchik, M.J.6
  • 48
    • 60449095987 scopus 로고    scopus 로고
    • Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production
    • Tsukamoto Y., Nagai Y., Kariyone A., Shibata T., Kaisho T., Akira S., Miyake K., Takatsu K. Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production. Mol. Immunol. 2009, 46:1278-1288.
    • (2009) Mol. Immunol. , vol.46 , pp. 1278-1288
    • Tsukamoto, Y.1    Nagai, Y.2    Kariyone, A.3    Shibata, T.4    Kaisho, T.5    Akira, S.6    Miyake, K.7    Takatsu, K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.