The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis

Arthritis Research and Therapy

Volumn 6, Issue 6, 2004, Pages 248-264

  Carrick, Danielle M ^a   Lai, Wi S ^a   Blackshear, Perry J ^a,b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

AU rich elements; Deadenylation; Granulocyte macrophage colony stimulating factor; mRNA turnover; Rheumatoid arthritis; Tumor necrosis factor

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIRHEUMATIC AGENT; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MESSENGER RNA; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AUTOIMMUNITY; BINDING SITE; BONE TURNOVER; CYTOKINE RELEASE; DISEASE SEVERITY; GENE EXPRESSION; GENE FREQUENCY; GENETIC CONSERVATION; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GENETIC VARIABILITY; GENOTYPE; HISTOPATHOLOGY; HUMAN; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN RNA BINDING; PROTEIN SYNTHESIS; PROTEIN TARGETING; REGULATORY MECHANISM; REVIEW; RHEUMATOID ARTHRITIS; RNA DEGRADATION; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ANIMALS; BASE SEQUENCE; BINDING SITES; BONE DISEASES, DEVELOPMENTAL; CROSSES, GENETIC; EPISTASIS, GENETIC; GENE EXPRESSION REGULATION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; MICE; MICE, KNOCKOUT; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHENOTYPE; POLYMORPHISM, GENETIC; PROTEIN BINDING; PROTEIN CONFORMATION; RNA, MESSENGER; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA; ZINC FINGERS;

EID: 8544255551     PISSN: 14786354     EISSN: None     Source Type: Journal    
DOI: 10.1186/ar1441     Document Type: Review

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