Autophagy-dependent viral recognition by plasmacytoid dendritic cells

Science

Volumn 315, Issue 5817, 2007, Pages 1398-1401

  Lee, Heung Kyu ^a   Lund, Jennifer M ^a   Ramanathan, Balaji ^a   Mizushima, Noboru ^a   Iwasaki, Akiko ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; ALPHA INTERFERON; SINGLE STRANDED RNA; TOLL LIKE RECEPTOR; VIRUS RNA; WORTMANNIN;

IMMUNE RESPONSE; PATHOGEN; RNA; VIRUS;

ACIDIFICATION; ANIMAL CELL; ARTICLE; AUTOPHAGY; CHICK EMBRYO; CONTROLLED STUDY; CYTOSOL; DENDRITIC CELL; ENDOSOME; INTERFERON PRODUCTION; LYSOSOME; MOLECULAR RECOGNITION; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; VIRUS CELL INTERACTION; VIRUS DETECTION; VIRUS PATHOGENESIS; VIRUS REPLICATION;

ANIMALS; AUTOPHAGY; DENDRITIC CELLS; ENDOSOMES; FEMALE; IMMUNITY, NATURAL; INTERFERON-ALPHA; INTERLEUKIN-12; LYSOSOMES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; PHAGOSOMES; RHABDOVIRIDAE INFECTIONS; RNA, VIRAL; TOLL-LIKE RECEPTOR 7; VESICULAR STOMATITIS-INDIANA VIRUS; VIRUS REPLICATION;

RNA VIRUSES;

EID: 33947134377     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1136880     Document Type: Article

References (31)

1. H. Kato et al., Nature 441, 101 (2006).
2. A. Pichlmair et al., Science 314, 997 (2006).
3. V. Hornung et al., Science 314, 994 (2006).
4. H. Kato et al., Immunity 23, 19 (2005).
5. A. Krug et al., Immunity 21, 107 (2004).
6. J. Lund, A. Sato, S. Akira, R. Medzhitov, A. Iwasaki, J. Exp. Med. 198, 513 (2003).
7. S. S. Diebold, T. Kaisho, H. Hemmi, S. Akira, C. Reis e Sousa, Science 303, 1529 (2004).
8. J. M. Lund et at., Proc. Natl. Acad. Sci. U.S.A. 101, 5598 (2004).
9. F. Heil et al., Science 303, 1526 (2004).
10. K. Yasuda et al., J. Immunol. 174, 6129 (2005).
11. A. Krug et al., Blood 103, 1433 (2004).
12. M. L. Eloranta, G. V. Alm, Scand. J. Immunol. 49, 391 (1999).
13. C. Asselin-Paturel et al., Nat. Immunol. 2, 1144 (2001).
14. A. S. Beignon et al., J. Clin. Invest. 115, 3265 (2005).
15. K. Crozat, B. Beutler, Proc. Natl. Acad. Sci. U.S.A. 101, 6835 (2004).
16. V. Hornung et at., J. Immunol. 173, 5935 (2004).
17. W. Barchet et al., J. Exp. Med. 195, 507 (2002).
18. Materials and methods are available as supporting material on Science Online.
19. D. F. Stojdl et al., Cancer Cell 4, 263 (2003).
20. C. von Kobbe et al., Mol. Cell 6, 1243 (2000).
21. N. Mizushima, Y. Ohsumi, T. Yoshimori, Cell Struct. Funct. 27, 421 (2002).
22. N. Mizushima, A. Yamamoto, M. Matsui, T. Yoshimori, Y. Ohsumi, Mol. Biol. Cell 15, 1101 (2004).
23. Y. Kabeya et al., EMBO J. 19, 5720 (2000).
24. P. O. Seglen, P. B. Gordon, Proc. Natl. Acad. Sci. U.S.A. 79, 1889 (1982).
25. E. F. Blommaart, U. Krause, J. P. Schellens, H. Vreeling-Sindelarova, A. J. Meijer, Eur. J. Biochem. 243, 240 (1997).
26. N. Araki, M. T. Johnson, J. A. Swanson, J. Cell Biol. 135, 1249 (1996).
27. A. Kuma et al., Nature 432, 1032 (2004).
28. Z. Talloczy et al., Proc. Natl. Acad. Sci. U.S.A. 99, 190 (2002).
29. Z. Talloczy, H. W. Virgin IV, B. Levine, Autophagy 2, 24 (2006).
30. W. T. Jackson et al., PLoS Biol. 3, e156 (2005).
31. We are grateful to J. Publicover and J. Rose for reagents and expertise, R. Medzhitov for critical review of the manuscript, W. Mothes for helpful discussions, and M. Zamora and G. Lyon for technical assistance. We thank P. J. Morrissey, B. Hall, and T. C. George of Amnis Corporation for analysis of samples using ImageStream technology. This work was supported by Public Health Service grants AI054359 and AI064705 (to A.I.) from NIH. J.M.L. was supported by the training grant AI07019 from NIH. H.K.L. was supported by the Ministry of Science and Technology of Korea. A.I. holds an Investigators in Pathogenesis of Infectious Disease Award from the Burroughs Wellcome Fund.