Inhibition of interleukin 1 receptor/toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

Journal of Experimental Medicine

Volumn 197, Issue 2, 2003, Pages 263-268

  Burns, Kimberly ^a   Janssens, Sophie ^b   Brissoni, Brian ^a   Olivos, Natalia ^a   Beyaert, Rudi ^b   Tschopp, Jürg ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

IL 1R; IRAK; MyD88; NF B; TLR

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN SERINE THREONINE KINASE; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; IMMUNE RESPONSE; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALTERNATIVE SPLICING; ANIMALS; ANTIGENS, DIFFERENTIATION; CELLS, CULTURED; DROSOPHILA PROTEINS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MEMBRANE GLYCOPROTEINS; MICE; MODELS, BIOLOGICAL; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; RECEPTORS, INTERLEUKIN-1; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 0037454946     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021790     Document Type: Article

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