The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

Nature Immunology

Volumn 7, Issue 2, 2006, Pages 156-164

  Tabeta, Koichi ^a   Hoebe, Kasper ^a   Janssen, Edith M ^b   Du, Xin ^a   Georgel, Philippe ^a   Crozat, Karine ^a   Mudd, Suzanne ^a   Mann, Navjiwan ^a   Sovath, Sosathya ^a   Goode, Jason ^a   Shamel, Louis ^a   Herskovits, Anat A ^c   Portnoy, Daniel A ^c   Cooke, Michael ^d   Tarantino, Lisa M ^d   Wiltshire, Tim ^d   Steinberg, Benjamin E ^e   Grinstein, Sergio ^e   Beutler, Bruce ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; DNA; DOUBLE STRANDED RNA; ETHYLNITROSOUREA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE PROTEIN; NUCLEIC ACID; PROTEIN UNC93B1; SINGLE STRANDED RNA; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CELL COMMUNICATION; CONTROLLED STUDY; CROSS PRESENTATION; CYTOMEGALOVIRUS; EMBRYO; ENDOPLASMIC RETICULUM; ENDOSOME; GENE MUTATION; GENETIC CODE; INFECTION SENSITIVITY; INNATE IMMUNITY; INTRACELLULAR SPACE; MAMMAL; MISSENSE MUTATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VIRUS INFECTION;

ANIMALS; ANTIGEN PRESENTATION; CLONING, MOLECULAR; ENDOPLASMIC RETICULUM; ENDOSOMES; HISTOCOMPATIBILITY ANTIGENS CLASS II; INFECTION; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MUTATION, MISSENSE; PHENOTYPE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 9;

EID: 31344466165     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1297     Document Type: Article

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