Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

Nature Immunology

Volumn 5, Issue 10, 2004, Pages 1061-1068

  Kawai, Taro ^a   Sato, Shintaro ^a   Ishii, Ken J ^a   Coban, Cevayir ^a   Hemmi, Hiroaki ^a   Yamamoto, Masahiro ^a   Terai, Kenta ^b   Matsuda, Michiyuki ^b   Inoue, Jun Ichiro ^c   Uematsu, Satoshi ^a   Takeuchi, Osamu ^a   Akira, Shizuo ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN PROTEIN LIGASE; CELL SURFACE RECEPTOR; DIFFERENTIATION ANTIGEN; DNA BINDING PROTEIN; IMMUNOGLOBULIN RECEPTOR; IRF7 PROTEIN, HUMAN; IRF7 PROTEIN, MOUSE; MEMBRANE PROTEIN; MYD88 PROTEIN, HUMAN; MYD88 PROTEIN, MOUSE; PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TLR7 PROTEIN, HUMAN; TLR8 PROTEIN, HUMAN; TLR9 PROTEIN, HUMAN; UBIQUITIN;

ARTICLE; CYTOKINE PRODUCTION; ENZYME ACTIVITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; UBIQUITINATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; HUMAN; METABOLISM; MOUSE; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; DNA-BINDING PROTEINS; HUMANS; INTERFERON REGULATORY FACTOR-7; INTERFERON-ALPHA; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS; UBIQUITIN;

EID: 5444274514     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1118     Document Type: Article

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