-
1
-
-
3142724031
-
Toll-like receptor signalling
-
Akira, S., and K. Takeda. 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4:499-511.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
2
-
-
0033776154
-
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor
-
Burns, K., J. Clatworthy, L. Martin, F. Martinon, C. Plumpton, B. Maschera, A. Lewis, K. Ray, J. Tschopp, and F. Volpe. 2000. Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor. Nat. Cell Biol. 2:346-351.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 346-351
-
-
Burns, K.1
Clatworthy, J.2
Martin, L.3
Martinon, F.4
Plumpton, C.5
Maschera, B.6
Lewis, A.7
Ray, K.8
Tschopp, J.9
Volpe, F.10
-
3
-
-
0037454946
-
Inhibition of interleukin 1 receptor/Toll-Iike receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
-
Burns, K., S. Janssens, B. Brissoni, N. Olivos, R. Beyaert, and J. Tschopp. 2003. Inhibition of interleukin 1 receptor/Toll-Iike receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J. Exp. Med. 197:263-268.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 263-268
-
-
Burns, K.1
Janssens, S.2
Brissoni, B.3
Olivos, N.4
Beyaert, R.5
Tschopp, J.6
-
4
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao, Z., J. Xiong, M. Takeuchi, T. Kurama, and D. V. Goeddel. 1996. TRAF6 is a signal transducer for interleukin-1. Nature 383:443-446.
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
5
-
-
3042686382
-
The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory
-
Hardy, M. P., and L. A. O'Neill. 2004. The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory. J. Biol. Chem. 279:27699-27708.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27699-27708
-
-
Hardy, M.P.1
O'Neill, L.A.2
-
6
-
-
0037292275
-
Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members
-
Janssens, S., and R. Beyaert. 2003. Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members. Mol. Cell 11:293-302.
-
(2003)
Mol. Cell
, vol.11
, pp. 293-302
-
-
Janssens, S.1
Beyaert, R.2
-
7
-
-
0036006290
-
Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88
-
Janssens, S., K. Burns, J. Tschopp, and R. Beyaert. 2002. Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88. Curr. Biol. 12:467-471.
-
(2002)
Curr. Biol.
, vol.12
, pp. 467-471
-
-
Janssens, S.1
Burns, K.2
Tschopp, J.3
Beyaert, R.4
-
8
-
-
0042236366
-
MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression
-
Janssens, S., K. Burns, E. Vercammen, J. Tschopp, and R. Beyaert. 2003. MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression. FEBS Lett. 548:103-107.
-
(2003)
FEBS Lett.
, vol.548
, pp. 103-107
-
-
Janssens, S.1
Burns, K.2
Vercammen, E.3
Tschopp, J.4
Beyaert, R.5
-
9
-
-
0035800878
-
IRAK1b, a novel alternative splice variant of interleukin-1 receptor-associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stability
-
Jensen, L. E., and A. S. Whitehead. 2001. IRAK1b, a novel alternative splice variant of interleukin-1 receptor-associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stability. J. Biol. Chem. 276:29037-29044.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29037-29044
-
-
Jensen, L.E.1
Whitehead, A.S.2
-
10
-
-
0036788753
-
Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol
-
Jiang, Z., J. Ninomiya-Tsuji, Y. Qian, K. Matsumoto, and X. Li. 2002. Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol. Mol. Cell. Biol. 22:7158-7167.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7158-7167
-
-
Jiang, Z.1
Ninomiya-Tsuji, J.2
Qian, Y.3
Matsumoto, K.4
Li, X.5
-
11
-
-
0033526110
-
Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficiem mice
-
Kanakaraj, P., K. Ngo, Y. Wu, A. Angulo, P. Ghazal, C. A. Harris, J. J. Siekierka, P. A. Peterson, and W. P. Fung-Leung. 1999. Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficiem mice. J. Exp. Med. 189:1129-1138.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1129-1138
-
-
Kanakaraj, P.1
Ngo, K.2
Wu, Y.3
Angulo, A.4
Ghazal, P.5
Harris, C.A.6
Siekierka, J.J.7
Peterson, P.A.8
Fung-Leung, W.P.9
-
12
-
-
0032526555
-
Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production
-
Kanakaraj, P., P. H. Schafer, D. E. Cavender, Y. Wu, K. Ngo, P. F. Grealish, S. A. Wadsworth, P. A. Peterson, J. J. Siekierka, C. A. Harris, and W. P. Fung-Leung. 1998. Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production. J. Exp. Med. 187:2073-2079.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 2073-2079
-
-
Kanakaraj, P.1
Schafer, P.H.2
Cavender, D.E.3
Wu, Y.4
Ngo, K.5
Grealish, P.F.6
Wadsworth, S.A.7
Peterson, P.A.8
Siekierka, J.J.9
Harris, C.A.10
Fung-Leung, W.P.11
-
13
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
Kobayashi, K., L. D. Hernandez, J. E. Galan, C. A. Janeway, Jr., R. Medzhitov, and R. A. Flavell. 2002. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 110:191-202.
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway Jr., C.A.4
Medzhitov, R.5
Flavell, R.A.6
-
14
-
-
1242272100
-
Sequential auto-phosphorylation steps in the interleukin-1 receptor-associated kinase-1 (IRAK-1) regulate its availability as an adapter in IL-1 signaling
-
Kollewe, C., A. C. Mackensen, D. Neumann, J. Knop, P. Cao, S. Li, H. Wesche, and M. U. Martin. 2004. Sequential auto-phosphorylation steps in the interleukin-1 receptor-associated kinase-1 (IRAK-1) regulate its availability as an adapter in IL-1 signaling. J. Biol. Chem. 279:5227-5236.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5227-5236
-
-
Kollewe, C.1
Mackensen, A.C.2
Neumann, D.3
Knop, J.4
Cao, P.5
Li, S.6
Wesche, H.7
Martin, M.U.8
-
15
-
-
0037117543
-
IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase
-
Li, S., A. Strelow, E. J. Fontana, and H. Wesche. 2002. IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase. Proc. Natl. Acad. Sci. USA 99:5567-5572.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5567-5572
-
-
Li, S.1
Strelow, A.2
Fontana, E.J.3
Wesche, H.4
-
16
-
-
0035836638
-
IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK)
-
Li, X., M. Commane, Z. Jiang, and G. R. Stark. 2001. IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK). Proc. Natl. Acad. Sci. USA 98:4461-4465.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4461-4465
-
-
Li, X.1
Commane, M.2
Jiang, Z.3
Stark, G.R.4
-
17
-
-
4644333526
-
The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling
-
Lye, E., C. Mirtsos, N. Suzuki, S. Suzuki, and W. C. Yeh. 2004. The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling. J. Biol. Chem. 279:40653-40658.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40653-40658
-
-
Lye, E.1
Mirtsos, C.2
Suzuki, N.3
Suzuki, S.4
Yeh, W.C.5
-
18
-
-
1342303482
-
Of mice and not men: Differences between mouse and human immunology
-
Mestas, J., and C. C. Hughes. 2004. Of mice and not men: differences between mouse and human immunology. J. Immunol. 172:2731-2738.
-
(2004)
J. Immunol.
, vol.172
, pp. 2731-2738
-
-
Mestas, J.1
Hughes, C.C.2
-
19
-
-
0037471003
-
Pyogenic bacterial infections in humans with IRAK-4 deficiency
-
Picard, C., A. Fuel, M. Bonnet, C. L. Ku, J. Bustamante, K. Yang, C. Soudais, S. Dupuis, J. Feinberg, C. Fieschi, C. Elbim, R. Hitchcock, D. Lammas, G. Davies, A. Al-Ghonaium, H. Al-Rayes, S. Al-Jumaah, S. Al-Hajjar, I. Z. Al-Mohsen, H. H. Frayha, R. Rucker, T. R. Hawn, A. Aderem, H. Tufenkeji, S. Haraguchi, N. K. Day, R. A. Good, M. A. Gougerot-Pocidalo, A. Ozinsky, and J. L. Casanova. 2003. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 299:2076-2079.
-
(2003)
Science
, vol.299
, pp. 2076-2079
-
-
Picard, C.1
Fuel, A.2
Bonnet, M.3
Ku, C.L.4
Bustamante, J.5
Yang, K.6
Soudais, C.7
Dupuis, S.8
Feinberg, J.9
Fieschi, C.10
Elbim, C.11
Hitchcock, R.12
Lammas, D.13
Davies, G.14
Al-Ghonaium, A.15
Al-Rayes, H.16
Al-Jumaah, S.17
Al-Hajjar, S.18
Al-Mohsen, I.Z.19
Frayha, H.H.20
Rucker, R.21
Hawn, T.R.22
Aderem, A.23
Tufenkeji, H.24
Haraguchi, S.25
Day, N.K.26
Good, R.A.27
Gougerot-Pocidalo, M.A.28
Ozinsky, A.29
Casanova, J.L.30
more..
-
20
-
-
0036915314
-
An essential role of ubiquitination in Cb1-mediated negative regulation of the Src-family kinase Fyn
-
Rao, N., A. K. Ghosh, P. Zhou, P. Douillard, C. E. Audoniou, and H. Band. 2002. An essential role of ubiquitination in Cb1-mediated negative regulation of the Src-family kinase Fyn. Signal Transduct. 2:29-39.
-
(2002)
Signal Transduct.
, vol.2
, pp. 29-39
-
-
Rao, N.1
Ghosh, A.K.2
Zhou, P.3
Douillard, P.4
Audoniou, C.E.5
Band, H.6
-
21
-
-
0036383057
-
Identification and characterization of murine IRAK-2
-
Rosati, O., and M. U. Martin. 2002. Identification and characterization of murine IRAK-2. Biochem. Biophys. Res. Commun. 297:52-58.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.297
, pp. 52-58
-
-
Rosati, O.1
Martin, M.U.2
-
22
-
-
0037129212
-
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
-
Suzuki, N., S. Suzuki, G. S. Duncan, D. G. Millar, T. Wada, C. Mirtsos, H. Takada, A. Wakeham, A. Itie, S. Li, J. M. Penninger, H. Wesche, P. S. Ohashi, T. W. Mak, and W. C. Yeh. 2002. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4. Nature 416:750-756.
-
(2002)
Nature
, vol.416
, pp. 750-756
-
-
Suzuki, N.1
Suzuki, S.2
Duncan, G.S.3
Millar, D.G.4
Wada, T.5
Mirtsos, C.6
Takada, H.7
Wakeham, A.8
Itie, A.9
Li, S.10
Penninger, J.M.11
Wesche, H.12
Ohashi, P.S.13
Mak, T.W.14
Yeh, W.C.15
-
23
-
-
0036882074
-
CD1-dependent dendritic cell instruction
-
Vincent, M. S., D. S. Leslie, J. E. Gumperz, X. Xiong, E. P. Grant, and M. B. Brenner. 2002. CD1-dependent dendritic cell instruction. Nat. Immunol. 3:1163-1168.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1163-1168
-
-
Vincent, M.S.1
Leslie, D.S.2
Gumperz, J.E.3
Xiong, X.4
Grant, E.P.5
Brenner, M.B.6
-
24
-
-
2142762520
-
TLRs: Differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression
-
Vogel, S. N., K. A. Fitzgerald, and M. J. Fenton. 2003. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 3:466-477.
-
(2003)
Mol. Interv.
, vol.3
, pp. 466-477
-
-
Vogel, S.N.1
Fitzgerald, K.A.2
Fenton, M.J.3
-
25
-
-
0033516561
-
IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family
-
Wesche, H., X. Gao, X. Li, C. J. Kirschning, G. R. Stark, and Z. Cao. 1999. IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family. J. Biol. Chem. 274:19403-19410.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19403-19410
-
-
Wesche, H.1
Gao, X.2
Li, X.3
Kirschning, C.J.4
Stark, G.R.5
Cao, Z.6
-
26
-
-
4544324500
-
Exip, a splicing variant of p38alpha, participates in interleukin-1 receptor proximal complex and down-regulates NF-kappaB pathway
-
Yagasaki, Y., T. Sudo, and H. Osada. 2004. Exip, a splicing variant of p38alpha, participates in interleukin-1 receptor proximal complex and down-regulates NF-kappaB pathway. FEBS Lett. 575:136-140.
-
(2004)
FEBS Lett.
, vol.575
, pp. 136-140
-
-
Yagasaki, Y.1
Sudo, T.2
Osada, H.3
-
27
-
-
0030868909
-
The interleukin-1 receptor-associated kinase is degraded by proteasomes following its phosphorylation
-
Yamin, T. T., and D. K. Miller. 1997. The interleukin-1 receptor-associated kinase is degraded by proteasomes following its phosphorylation. J. Biol. Chem. 272:21540-21547.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21540-21547
-
-
Yamin, T.T.1
Miller, D.K.2
-
28
-
-
0037442535
-
A novel splice variant of mouse interleukin-1-receptor-associated kinase-1 (IRAK-1) activates nuclear factor-kappaB (NF-kappaB) and c-Jun N-terminal kinase (JNK)
-
Yanagisawa, K., K. Tago, M. Hayakawa, M. Ohki, H. Iwahana, and S. Tominaga. 2003. A novel splice variant of mouse interleukin-1-receptor- associated kinase-1 (IRAK-1) activates nuclear factor-kappaB (NF-kappaB) and c-Jun N-terminal kinase (JNK). Biochem. J. 370:159-166.
-
(2003)
Biochem. J.
, vol.370
, pp. 159-166
-
-
Yanagisawa, K.1
Tago, K.2
Hayakawa, M.3
Ohki, M.4
Iwahana, H.5
Tominaga, S.6
-
29
-
-
0037438350
-
CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: Alterations in IL-1 receptor-associated kinase expression
-
Yeo, S. J., J. G. Yoon, S. C. Hong, and A. K. Yi. 2003. CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: alterations in IL-1 receptor-associated kinase expression. J. Immunol. 170:1052-1061.
-
(2003)
J. Immunol.
, vol.170
, pp. 1052-1061
-
-
Yeo, S.J.1
Yoon, J.G.2
Hong, S.C.3
Yi, A.K.4
|