메뉴 건너뛰기




Volumn 25, Issue 15, 2005, Pages 6521-6532

A novel splice variant of interleukin-1 receptor (IL-1R)-Associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1C; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHOTRANSFERASE; PROTEIN; RECEPTOR; RNA; TOLL INTERLEUKIN 1 RECEPTOR; TOLLIP PROTEIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

EID: 22544451204     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.15.6521-6532.2005     Document Type: Article
Times cited : (93)

References (29)
  • 1
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira, S., and K. Takeda. 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4:499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 3
    • 0037454946 scopus 로고    scopus 로고
    • Inhibition of interleukin 1 receptor/Toll-Iike receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
    • Burns, K., S. Janssens, B. Brissoni, N. Olivos, R. Beyaert, and J. Tschopp. 2003. Inhibition of interleukin 1 receptor/Toll-Iike receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J. Exp. Med. 197:263-268.
    • (2003) J. Exp. Med. , vol.197 , pp. 263-268
    • Burns, K.1    Janssens, S.2    Brissoni, B.3    Olivos, N.4    Beyaert, R.5    Tschopp, J.6
  • 4
    • 0029761275 scopus 로고    scopus 로고
    • TRAF6 is a signal transducer for interleukin-1
    • Cao, Z., J. Xiong, M. Takeuchi, T. Kurama, and D. V. Goeddel. 1996. TRAF6 is a signal transducer for interleukin-1. Nature 383:443-446.
    • (1996) Nature , vol.383 , pp. 443-446
    • Cao, Z.1    Xiong, J.2    Takeuchi, M.3    Kurama, T.4    Goeddel, D.V.5
  • 5
    • 3042686382 scopus 로고    scopus 로고
    • The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory
    • Hardy, M. P., and L. A. O'Neill. 2004. The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory. J. Biol. Chem. 279:27699-27708.
    • (2004) J. Biol. Chem. , vol.279 , pp. 27699-27708
    • Hardy, M.P.1    O'Neill, L.A.2
  • 6
    • 0037292275 scopus 로고    scopus 로고
    • Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members
    • Janssens, S., and R. Beyaert. 2003. Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members. Mol. Cell 11:293-302.
    • (2003) Mol. Cell , vol.11 , pp. 293-302
    • Janssens, S.1    Beyaert, R.2
  • 7
    • 0036006290 scopus 로고    scopus 로고
    • Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88
    • Janssens, S., K. Burns, J. Tschopp, and R. Beyaert. 2002. Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88. Curr. Biol. 12:467-471.
    • (2002) Curr. Biol. , vol.12 , pp. 467-471
    • Janssens, S.1    Burns, K.2    Tschopp, J.3    Beyaert, R.4
  • 8
    • 0042236366 scopus 로고    scopus 로고
    • MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression
    • Janssens, S., K. Burns, E. Vercammen, J. Tschopp, and R. Beyaert. 2003. MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression. FEBS Lett. 548:103-107.
    • (2003) FEBS Lett. , vol.548 , pp. 103-107
    • Janssens, S.1    Burns, K.2    Vercammen, E.3    Tschopp, J.4    Beyaert, R.5
  • 9
    • 0035800878 scopus 로고    scopus 로고
    • IRAK1b, a novel alternative splice variant of interleukin-1 receptor-associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stability
    • Jensen, L. E., and A. S. Whitehead. 2001. IRAK1b, a novel alternative splice variant of interleukin-1 receptor-associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stability. J. Biol. Chem. 276:29037-29044.
    • (2001) J. Biol. Chem. , vol.276 , pp. 29037-29044
    • Jensen, L.E.1    Whitehead, A.S.2
  • 10
    • 0036788753 scopus 로고    scopus 로고
    • Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol
    • Jiang, Z., J. Ninomiya-Tsuji, Y. Qian, K. Matsumoto, and X. Li. 2002. Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol. Mol. Cell. Biol. 22:7158-7167.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7158-7167
    • Jiang, Z.1    Ninomiya-Tsuji, J.2    Qian, Y.3    Matsumoto, K.4    Li, X.5
  • 11
    • 0033526110 scopus 로고    scopus 로고
    • Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficiem mice
    • Kanakaraj, P., K. Ngo, Y. Wu, A. Angulo, P. Ghazal, C. A. Harris, J. J. Siekierka, P. A. Peterson, and W. P. Fung-Leung. 1999. Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficiem mice. J. Exp. Med. 189:1129-1138.
    • (1999) J. Exp. Med. , vol.189 , pp. 1129-1138
    • Kanakaraj, P.1    Ngo, K.2    Wu, Y.3    Angulo, A.4    Ghazal, P.5    Harris, C.A.6    Siekierka, J.J.7    Peterson, P.A.8    Fung-Leung, W.P.9
  • 14
    • 1242272100 scopus 로고    scopus 로고
    • Sequential auto-phosphorylation steps in the interleukin-1 receptor-associated kinase-1 (IRAK-1) regulate its availability as an adapter in IL-1 signaling
    • Kollewe, C., A. C. Mackensen, D. Neumann, J. Knop, P. Cao, S. Li, H. Wesche, and M. U. Martin. 2004. Sequential auto-phosphorylation steps in the interleukin-1 receptor-associated kinase-1 (IRAK-1) regulate its availability as an adapter in IL-1 signaling. J. Biol. Chem. 279:5227-5236.
    • (2004) J. Biol. Chem. , vol.279 , pp. 5227-5236
    • Kollewe, C.1    Mackensen, A.C.2    Neumann, D.3    Knop, J.4    Cao, P.5    Li, S.6    Wesche, H.7    Martin, M.U.8
  • 15
    • 0037117543 scopus 로고    scopus 로고
    • IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase
    • Li, S., A. Strelow, E. J. Fontana, and H. Wesche. 2002. IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase. Proc. Natl. Acad. Sci. USA 99:5567-5572.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5567-5572
    • Li, S.1    Strelow, A.2    Fontana, E.J.3    Wesche, H.4
  • 16
    • 0035836638 scopus 로고    scopus 로고
    • IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK)
    • Li, X., M. Commane, Z. Jiang, and G. R. Stark. 2001. IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK). Proc. Natl. Acad. Sci. USA 98:4461-4465.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4461-4465
    • Li, X.1    Commane, M.2    Jiang, Z.3    Stark, G.R.4
  • 17
    • 4644333526 scopus 로고    scopus 로고
    • The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling
    • Lye, E., C. Mirtsos, N. Suzuki, S. Suzuki, and W. C. Yeh. 2004. The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling. J. Biol. Chem. 279:40653-40658.
    • (2004) J. Biol. Chem. , vol.279 , pp. 40653-40658
    • Lye, E.1    Mirtsos, C.2    Suzuki, N.3    Suzuki, S.4    Yeh, W.C.5
  • 18
    • 1342303482 scopus 로고    scopus 로고
    • Of mice and not men: Differences between mouse and human immunology
    • Mestas, J., and C. C. Hughes. 2004. Of mice and not men: differences between mouse and human immunology. J. Immunol. 172:2731-2738.
    • (2004) J. Immunol. , vol.172 , pp. 2731-2738
    • Mestas, J.1    Hughes, C.C.2
  • 20
    • 0036915314 scopus 로고    scopus 로고
    • An essential role of ubiquitination in Cb1-mediated negative regulation of the Src-family kinase Fyn
    • Rao, N., A. K. Ghosh, P. Zhou, P. Douillard, C. E. Audoniou, and H. Band. 2002. An essential role of ubiquitination in Cb1-mediated negative regulation of the Src-family kinase Fyn. Signal Transduct. 2:29-39.
    • (2002) Signal Transduct. , vol.2 , pp. 29-39
    • Rao, N.1    Ghosh, A.K.2    Zhou, P.3    Douillard, P.4    Audoniou, C.E.5    Band, H.6
  • 21
    • 0036383057 scopus 로고    scopus 로고
    • Identification and characterization of murine IRAK-2
    • Rosati, O., and M. U. Martin. 2002. Identification and characterization of murine IRAK-2. Biochem. Biophys. Res. Commun. 297:52-58.
    • (2002) Biochem. Biophys. Res. Commun. , vol.297 , pp. 52-58
    • Rosati, O.1    Martin, M.U.2
  • 24
    • 2142762520 scopus 로고    scopus 로고
    • TLRs: Differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression
    • Vogel, S. N., K. A. Fitzgerald, and M. J. Fenton. 2003. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 3:466-477.
    • (2003) Mol. Interv. , vol.3 , pp. 466-477
    • Vogel, S.N.1    Fitzgerald, K.A.2    Fenton, M.J.3
  • 25
    • 0033516561 scopus 로고    scopus 로고
    • IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family
    • Wesche, H., X. Gao, X. Li, C. J. Kirschning, G. R. Stark, and Z. Cao. 1999. IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family. J. Biol. Chem. 274:19403-19410.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19403-19410
    • Wesche, H.1    Gao, X.2    Li, X.3    Kirschning, C.J.4    Stark, G.R.5    Cao, Z.6
  • 26
    • 4544324500 scopus 로고    scopus 로고
    • Exip, a splicing variant of p38alpha, participates in interleukin-1 receptor proximal complex and down-regulates NF-kappaB pathway
    • Yagasaki, Y., T. Sudo, and H. Osada. 2004. Exip, a splicing variant of p38alpha, participates in interleukin-1 receptor proximal complex and down-regulates NF-kappaB pathway. FEBS Lett. 575:136-140.
    • (2004) FEBS Lett. , vol.575 , pp. 136-140
    • Yagasaki, Y.1    Sudo, T.2    Osada, H.3
  • 27
    • 0030868909 scopus 로고    scopus 로고
    • The interleukin-1 receptor-associated kinase is degraded by proteasomes following its phosphorylation
    • Yamin, T. T., and D. K. Miller. 1997. The interleukin-1 receptor-associated kinase is degraded by proteasomes following its phosphorylation. J. Biol. Chem. 272:21540-21547.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21540-21547
    • Yamin, T.T.1    Miller, D.K.2
  • 28
    • 0037442535 scopus 로고    scopus 로고
    • A novel splice variant of mouse interleukin-1-receptor-associated kinase-1 (IRAK-1) activates nuclear factor-kappaB (NF-kappaB) and c-Jun N-terminal kinase (JNK)
    • Yanagisawa, K., K. Tago, M. Hayakawa, M. Ohki, H. Iwahana, and S. Tominaga. 2003. A novel splice variant of mouse interleukin-1-receptor- associated kinase-1 (IRAK-1) activates nuclear factor-kappaB (NF-kappaB) and c-Jun N-terminal kinase (JNK). Biochem. J. 370:159-166.
    • (2003) Biochem. J. , vol.370 , pp. 159-166
    • Yanagisawa, K.1    Tago, K.2    Hayakawa, M.3    Ohki, M.4    Iwahana, H.5    Tominaga, S.6
  • 29
    • 0037438350 scopus 로고    scopus 로고
    • CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: Alterations in IL-1 receptor-associated kinase expression
    • Yeo, S. J., J. G. Yoon, S. C. Hong, and A. K. Yi. 2003. CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: alterations in IL-1 receptor-associated kinase expression. J. Immunol. 170:1052-1061.
    • (2003) J. Immunol. , vol.170 , pp. 1052-1061
    • Yeo, S.J.1    Yoon, J.G.2    Hong, S.C.3    Yi, A.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.