Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3-and viral-induced expression of type i interferons

Nature Immunology

Volumn 13, Issue 11, 2012, Pages 1055-1062

  Siednienko, Jakub ^a   Jackson, Ruaidhri ^a   Mellett, Mark ^a   Delagic, Nezira ^a   Yang, Shuo ^a   Wang, Bingwei ^a   Tang, Lisa S ^a   Callanan, John J ^b   Mahon, Bernard P ^a   Moynagh, Paul N ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; INTERFERON REGULATORY FACTOR 7; PELLINO3 PROTEIN; REGULATOR PROTEIN; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; AUTOREGULATION; CONTROLLED STUDY; DOWN REGULATION; ENCEPHALOMYOCARDITIS VIRUS; GENE DELETION; IMMUNOREGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; VIRUS RESISTANCE;

ANIMALS; CARDIOVIRUS INFECTIONS; ENCEPHALOMYOCARDITIS VIRUS; GENE EXPRESSION REGULATION; HOMEOSTASIS; INTERFERON REGULATORY FACTOR-7; INTERFERON TYPE I; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SURVIVAL RATE; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 3; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84867744278     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2429     Document Type: Article

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