Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

Nature

Volumn 458, Issue 7242, 2009, Pages 1185-1190

  Matsushita, Kazufumi ^a,c   Takeuchi, Osamu ^a,c   Standley, Daron M ^b   Kumagai, Yutaro ^a,c   Kawagoe, Tatsukata ^a,c   Miyake, Tohru ^a,c   Satoh, Takashi ^a,c   Kato, Hiroki ^a,c   Tsujimura, Tohru ^d   Nakamura, Haruki ^a   Akira, Shizuo ^a,c  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 12P40; INTERLEUKIN 6; MESSENGER RNA; RIBONUCLEASE; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR;

ANTIBODY; CELL ORGANELLE; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNE RESPONSE; INFILTRATION; RNA;

3' UNTRANSLATED REGION; ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; GENE; GENE FUNCTION; GENE ZC3H12A; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION;

3' UNTRANSLATED REGIONS; ANEMIA; ANIMALS; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CELL LINE; CYTOKINES; FETAL DISEASES; HUMANS; IMMUNITY; INFLAMMATION MEDIATORS; INTERLEUKIN-6; MACROPHAGES, PERITONEAL; MICE; PLASMA CELLS; RIBONUCLEASES; RNA STABILITY; T-LYMPHOCYTES;

MUS;

EID: 67349167059     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature07924     Document Type: Article

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