메뉴 건너뛰기




Volumn 2 JUN, Issue , 2012, Pages

Radiation, inflammation, and immune responses in cancer

Author keywords

Heat shock proteins; HIF 1; Inflammation; NF B; PGHS 2; Radiation; Radioresistance; STAT 3

Indexed keywords

CELECOXIB; CURCUMIN; DOCOSAHEXAENOIC ACID; FIBROBLAST GROWTH FACTOR 2; FLUOROURACIL; GELATINASE B; GEMCITABINE; GOLNERMINOGENE PRADENOVEC; HEAT SHOCK PROTEIN 70; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 6; MISMATCH REPAIR PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NIVOCASAN; PITAVASTATIN; PROSTAGLANDIN SYNTHASE; PROTEIN MSH2; PROTEIN MSH6; PROTEIN TYROSINE PHOSPHATASE; SEX HORMONE; STAT PROTEIN; TUMOR NECROSIS FACTOR; VASCULOTROPIN;

EID: 84875221247     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2012.00058     Document Type: Review
Times cited : (167)

References (214)
  • 1
    • 0030218796 scopus 로고    scopus 로고
    • Effect of irradiation on cytokine production, MHC antigen expression, and vaccine potential of interleukin-2 and interferon-gamma gene-modified melanoma cells
    • Abdel-Wahab, Z., Dar, M. M., Hester, D., Vervaert, C., Gangavalli, R., Barber, J., Darrow, T. L., and Seigler, H. F. (1996). Effect of irradiation on cytokine production, MHC antigen expression, and vaccine potential of interleukin-2 and interferon-gamma gene-modified melanoma cells. Cell. Immunol. 171, 246-254.
    • (1996) Cell. Immunol. , vol.171 , pp. 246-254
    • Abdel-Wahab, Z.1    Dar, M.M.2    Hester, D.3    Vervaert, C.4    Gangavalli, R.5    Barber, J.6    Darrow, T.L.7    Seigler, H.F.8
  • 2
    • 0027056675 scopus 로고
    • Irradiation increases levels of GM-CSF through RNA stabilization which requires an AU-rich region in cancer cells
    • Akashi, M., Hachiya, M., Koeffler, H. P., and Suzuki, G. (1992). Irradiation increases levels of GM-CSF through RNA stabilization which requires an AU-rich region in cancer cells. Biochem. Biophys. Res. Commun. 189, 986-993.
    • (1992) Biochem. Biophys. Res. Commun. , vol.189 , pp. 986-993
    • Akashi, M.1    Hachiya, M.2    Koeffler, H.P.3    Suzuki, G.4
  • 3
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira, S., and Takeda, K. (2004). Toll-like receptor signalling. Nat. Rev. Immunol. 4, 499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 4
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira, S., Uematsu, S., and Takeuchi, O. (2006). Pathogen recognition and innate immunity. Cell 124, 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 5
    • 33745095268 scopus 로고    scopus 로고
    • Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer
    • Albert, J. M., Kim, K. W., Cao, C., and Lu, B. (2006). Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer. Mol. Cancer Ther. 5, 1183-1189.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 1183-1189
    • Albert, J.M.1    Kim, K.W.2    Cao, C.3    Lu, B.4
  • 8
    • 80052464851 scopus 로고    scopus 로고
    • Low doses of the novel caspase-inhibitor GS-9450 leads to lower caspase-3 and-8 expression on peripheral CD4+ and CD8+ T-cells
    • Arends, J. E., Hoepelman, A. I., Nanlohy, N. M., Höppener, F. J., Hirsch, K. R., Park, J. G., and van Baarle, D. (2011). Low doses of the novel caspase-inhibitor GS-9450 leads to lower caspase-3 and-8 expression on peripheral CD4+ and CD8+ T-cells. Apoptosis 16, 959-966.
    • (2011) Apoptosis , vol.16 , pp. 959-966
    • Arends, J.E.1    Hoepelman, A.I.2    Nanlohy, N.M.3    Höppener, F.J.4    Hirsch, K.R.5    Park, J.G.6    van Baarle, D.7
  • 9
    • 0034613163 scopus 로고    scopus 로고
    • ATP and ADP modulate a cation channel formed by Hsc70 in acidic phospholipid membranes
    • Arispe, N., and De Maio, A. (2000). ATP and ADP modulate a cation channel formed by Hsc70 in acidic phospholipid membranes. J. Biol. Chem. 275, 30839-30843.
    • (2000) J. Biol. Chem. , vol.275 , pp. 30839-30843
    • Arispe, N.1    De Maio, A.2
  • 10
    • 0036819191 scopus 로고    scopus 로고
    • Lipid interaction differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70
    • Arispe, N., Doh, M., and De Maio, A. (2002). Lipid interaction differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70. Cell Stress Chaperones 7, 330-338.
    • (2002) Cell Stress Chaperones , vol.7 , pp. 330-338
    • Arispe, N.1    Doh, M.2    De Maio, A.3
  • 11
    • 0034113617 scopus 로고    scopus 로고
    • HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine
    • Asea, A., Kraeft, S. K., Kurt-Jones, E. A., Stevenson, M. A., Chen, L. B., Finberg, R. W., Koo, G. C., and Calderwood, S. K. (2000). HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat. Med. 6, 435-442.
    • (2000) Nat. Med. , vol.6 , pp. 435-442
    • Asea, A.1    Kraeft, S.K.2    Kurt-Jones, E.A.3    Stevenson, M.A.4    Chen, L.B.5    Finberg, R.W.6    Koo, G.C.7    Calderwood, S.K.8
  • 12
    • 0037177825 scopus 로고    scopus 로고
    • Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4
    • Asea, A., Rehli, M., Kabingu, E., Boch, J. A., Bare, O., Auron, P. E., Stevenson, M. A., and Calderwood, S. K. (2002). Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J. Biol. Chem. 277, 15028-15034.
    • (2002) J. Biol. Chem. , vol.277 , pp. 15028-15034
    • Asea, A.1    Rehli, M.2    Kabingu, E.3    Boch, J.A.4    Bare, O.5    Auron, P.E.6    Stevenson, M.A.7    Calderwood, S.K.8
  • 13
    • 79952300115 scopus 로고    scopus 로고
    • Sensitivity to low-dose/low-LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondria-derived reactive oxygen species
    • Aykin-Burns, N., Slane, B. G., Liu, A. T., Owens, K. M., O'Malley, M. S., Smith, B. J., Domann, F. E., and Spitz, D. R. (2011). Sensitivity to low-dose/low-LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondria-derived reactive oxygen species. Radiat. Res. 175, 150-158.
    • (2011) Radiat. Res. , vol.175 , pp. 150-158
    • Aykin-Burns, N.1    Slane, B.G.2    Liu, A.T.3    Owens, K.M.4    O'Malley, M.S.5    Smith, B.J.6    Domann, F.E.7    Spitz, D.R.8
  • 14
    • 10944243759 scopus 로고    scopus 로고
    • Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
    • Balasubramanyam, K., Varier, R. A., Altaf, M., Swaminathan, V., Siddappa, N. B., Ranga, U., and Kundu, T. K. (2004). Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J. Biol. Chem. 279, 51163-51171.
    • (2004) J. Biol. Chem. , vol.279 , pp. 51163-51171
    • Balasubramanyam, K.1    Varier, R.A.2    Altaf, M.3    Swaminathan, V.4    Siddappa, N.B.5    Ranga, U.6    Kundu, T.K.7
  • 15
    • 50549123220 scopus 로고
    • On the treatment of inoperable cases of carcinoma of the mamma: suggestions for a new method of treatment, with illustrative cases
    • Beatson, G. T. (1896a). On the treatment of inoperable cases of carcinoma of the mamma: suggestions for a new method of treatment, with illustrative cases. Lancet 2, 104-107.
    • (1896) Lancet , vol.2 , pp. 104-107
    • Beatson, G.T.1
  • 16
    • 42949121365 scopus 로고
    • On the treatment of inoperable cases of carcinoma of the mamma: suggestions for a new method of treatment, with illustrative cases
    • Beatson, G. T. (1896b). On the treatment of inoperable cases of carcinoma of the mamma: suggestions for a new method of treatment, with illustrative cases. Lancet 2, 162-165.
    • (1896) Lancet , vol.2 , pp. 162-165
    • Beatson, G.T.1
  • 17
    • 31344442461 scopus 로고    scopus 로고
    • Inflammation-associated immune suppression in cancer: the roles played by cytokines, chemokines and additional mediators
    • Ben Baruch, A. (2006). Inflammation-associated immune suppression in cancer: the roles played by cytokines, chemokines and additional mediators. Semin. Cancer Biol. 16, 38-52.
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 38-52
    • Ben Baruch, A.1
  • 18
    • 80052014052 scopus 로고    scopus 로고
    • Inflammation meets cancer, with NF-κB as the matchmaker
    • Ben-Neriah, Y., and Karin, M. (2011). Inflammation meets cancer, with NF-κB as the matchmaker. Nat. Immunol. 12, 715-723.
    • (2011) Nat. Immunol. , vol.12 , pp. 715-723
    • Ben-Neriah, Y.1    Karin, M.2
  • 19
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: all we need to know about danger
    • Bianchi, M. E. (2007). DAMPs, PAMPs and alarmins: all we need to know about danger. J. Leukoc. Biol. 81, 1-5.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 20
    • 9144261127 scopus 로고    scopus 로고
    • Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity
    • Bisht, K. S., Bradbury, C. M., Mattson, D., Kaushal, A., Sowers, A., Markovina, S., Ortiz, K. L., Sieck, L. K., Isaacs, J. S., Brechbiel, M. W., Mitchell, J. B., Neckers, L. M., and Gius, D. (2003). Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity. Cancer Res. 63, 8984-8995.
    • (2003) Cancer Res. , vol.63 , pp. 8984-8995
    • Bisht, K.S.1    Bradbury, C.M.2    Mattson, D.3    Kaushal, A.4    Sowers, A.5    Markovina, S.6    Ortiz, K.L.7    Sieck, L.K.8    Isaacs, J.S.9    Brechbiel, M.W.10    Mitchell, J.B.11    Neckers, L.M.12    Gius, D.13
  • 22
    • 78049438246 scopus 로고    scopus 로고
    • Targeting COX-2 expression by natural compounds: a promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy
    • Cerella, C., Sobolewski, C., Dicato, M., and Diederich, M. (2010). Targeting COX-2 expression by natural compounds: a promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy. Biochem. Pharmacol. 80, 1801-1815.
    • (2010) Biochem. Pharmacol. , vol.80 , pp. 1801-1815
    • Cerella, C.1    Sobolewski, C.2    Dicato, M.3    Diederich, M.4
  • 24
    • 79953782203 scopus 로고    scopus 로고
    • NF-κB addiction and its role in cancer: 'one size does not fit all'.
    • Chaturvedi, M. M., Sung, B., Yadav, V. R., Kannappan, R., and Aggarwal, B. B. (2011). NF-κB addiction and its role in cancer: "one size does not fit all." Oncogene 30, 1615-1630.
    • (2011) Oncogene , vol.30 , pp. 1615-1630
    • Chaturvedi, M.M.1    Sung, B.2    Yadav, V.R.3    Kannappan, R.4    Aggarwal, B.B.5
  • 25
    • 77954790516 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis
    • Che, S. M., Zhang, X. Z., Hou, L., and Song, T. B. (2010). Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis. Cancer Invest. 28, 679-688.
    • (2010) Cancer Invest. , vol.28 , pp. 679-688
    • Che, S.M.1    Zhang, X.Z.2    Hou, L.3    Song, T.B.4
  • 26
    • 79953696909 scopus 로고    scopus 로고
    • The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells
    • Che, S. M., Zhang, X. Z., Liu, X. L., Chen, X., and Hou, L. (2011). The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells. Dis. Esophagus 24, 265-273.
    • (2011) Dis. Esophagus , vol.24 , pp. 265-273
    • Che, S.M.1    Zhang, X.Z.2    Liu, X.L.3    Chen, X.4    Hou, L.5
  • 27
    • 84863151419 scopus 로고    scopus 로고
    • Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer
    • Chen, J., Wang, J., Lin, L., He, L., Wu, Y., Zhang, L., Yi, Z., Chen, Y., Pang, X., and Liu, M. (2012a). Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer. Mol. Cancer Ther. 11, 277-287.
    • (2012) Mol. Cancer Ther. , vol.11 , pp. 277-287
    • Chen, J.1    Wang, J.2    Lin, L.3    He, L.4    Wu, Y.5    Zhang, L.6    Yi, Z.7    Chen, Y.8    Pang, X.9    Liu, M.10
  • 28
    • 84855418556 scopus 로고    scopus 로고
    • Inhibition of the STAT3 signaling pathway is involved in the antitumor activity of cepharanthine in SaOS2 cells
    • Chen, Z., Huang, C., Yang, Y. L., Ding, Y., Ou-Yang, H. Q., Zhang, Y. Y., and Xu, M. (2012b). Inhibition of the STAT3 signaling pathway is involved in the antitumor activity of cepharanthine in SaOS2 cells. Acta Pharmacol. Sin. 33, 101-108.
    • (2012) Acta Pharmacol. Sin. , vol.33 , pp. 101-108
    • Chen, Z.1    Huang, C.2    Yang, Y.L.3    Ding, Y.4    Ou-Yang, H.Q.5    Zhang, Y.Y.6    Xu, M.7
  • 30
    • 1542426626 scopus 로고    scopus 로고
    • Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3
    • Chendil, D., Ranga, R. S., Meigooni, D., Sathishkumar, S., and Ahmed, M. M. (2004). Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3. Oncogene 23, 1599-1607.
    • (2004) Oncogene , vol.23 , pp. 1599-1607
    • Chendil, D.1    Ranga, R.S.2    Meigooni, D.3    Sathishkumar, S.4    Ahmed, M.M.5
  • 31
    • 33750890673 scopus 로고    scopus 로고
    • Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-κB signal transduction pathway
    • Cheng, J. C., Chou, C. H., Kuo, M. L., and Hsieh, C. Y. (2006). Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-κB signal transduction pathway. Oncogene 25, 7009-7018.
    • (2006) Oncogene , vol.25 , pp. 7009-7018
    • Cheng, J.C.1    Chou, C.H.2    Kuo, M.L.3    Hsieh, C.Y.4
  • 32
    • 85047683640 scopus 로고    scopus 로고
    • Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor
    • Cheng, S., Brzostek, S., Lee, S. R., Hollenberg, A. N., and Balk, S. P. (2002). Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor. Mol. Endocrinol. 16, 1492-1501.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 1492-1501
    • Cheng, S.1    Brzostek, S.2    Lee, S.R.3    Hollenberg, A.N.4    Balk, S.P.5
  • 34
    • 0032825507 scopus 로고    scopus 로고
    • Ionizing radiation enhances immunogenicity of cells expressing a tumor-specific T-cell epitope
    • Ciernik, I. F., Romero, P., Berzofsky, J. A., and Carbone, D. P. (1999). Ionizing radiation enhances immunogenicity of cells expressing a tumor-specific T-cell epitope. Int. J. Radiat. Oncol. Biol. Phys. 45, 735-741.
    • (1999) Int. J. Radiat. Oncol. Biol. Phys. , vol.45 , pp. 735-741
    • Ciernik, I.F.1    Romero, P.2    Berzofsky, J.A.3    Carbone, D.P.4
  • 35
    • 0035072953 scopus 로고    scopus 로고
    • Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
    • Coleman, M. L., Sahai, E. A., Yeo, M., Bosch, M., Dewar, A., and Olson, M. F. (2001). Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat. Cell Biol. 3, 339-345.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 339-345
    • Coleman, M.L.1    Sahai, E.A.2    Yeo, M.3    Bosch, M.4    Dewar, A.5    Olson, M.F.6
  • 36
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
    • Colotta, F., Allavena, P., Sica, A., Garlanda, C., and Mantovani, A. (2009). Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 30, 1073-1081.
    • (2009) Carcinogenesis , vol.30 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 37
    • 79958748545 scopus 로고    scopus 로고
    • Extracellular heat shock proteins, cellular export vesicles, and the stress observation system: a form of communication during injury, infection, and cell damage. It is never known how far a controversial finding will go! Dedicated to Ferruccio Ritossa
    • De Maio, A. (2011). Extracellular heat shock proteins, cellular export vesicles, and the stress observation system: a form of communication during injury, infection, and cell damage. It is never known how far a controversial finding will go! Dedicated to Ferruccio Ritossa. Cell Stress Chaperones 16, 235-249.
    • (2011) Cell Stress Chaperones , vol.16 , pp. 235-249
    • De Maio, A.1
  • 38
    • 78049441629 scopus 로고    scopus 로고
    • Targeting inflammatory pathways for tumor radiosensitization
    • Deorukhkar, A., and Krishnan, S. (2010). Targeting inflammatory pathways for tumor radiosensitization. Biochem. Pharmacol. 80, 1904-1914.
    • (2010) Biochem. Pharmacol. , vol.80 , pp. 1904-1914
    • Deorukhkar, A.1    Krishnan, S.2
  • 39
    • 36049051459 scopus 로고    scopus 로고
    • Back to basics: how natural products can provide the basis for new therapeutics
    • Deorukhkar, A., Krishnan, S., Sethi, G., and Aggarwal, B. B. (2007). Back to basics: how natural products can provide the basis for new therapeutics. Expert. Opin. Investig. Drugs 16, 1753-1773.
    • (2007) Expert. Opin. Investig. Drugs , vol.16 , pp. 1753-1773
    • Deorukhkar, A.1    Krishnan, S.2    Sethi, G.3    Aggarwal, B.B.4
  • 41
    • 37049038610 scopus 로고    scopus 로고
    • Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism
    • Dittmann, K. H., Mayer, C., Ohneseit, P. A., Raju, U., Andratschke, N. H., Milas, L., and Rodemann, H. P. (2008). Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism. Int. J. Radiat. Oncol. Biol. Phys. 70, 203-212.
    • (2008) Int. J. Radiat. Oncol. Biol. Phys. , vol.70 , pp. 203-212
    • Dittmann, K.H.1    Mayer, C.2    Ohneseit, P.A.3    Raju, U.4    Andratschke, N.H.5    Milas, L.6    Rodemann, H.P.7
  • 43
    • 68649102975 scopus 로고    scopus 로고
    • Mechanisms of interleukin-1β release
    • Eder, C. (2009). Mechanisms of interleukin-1β release. Immunobiology 214, 543-553.
    • (2009) Immunobiology , vol.214 , pp. 543-553
    • Eder, C.1
  • 44
    • 51249087746 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers
    • Endo, Y., Marusawa, H., Kou, T., Nakase, H., Fujii, S., Fujimori, T., Kinoshita, K., Honjo, T., and Chiba, T. (2008). Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers. Gastroenterology 135, 889-898.
    • (2008) Gastroenterology , vol.135 , pp. 889-898
    • Endo, Y.1    Marusawa, H.2    Kou, T.3    Nakase, H.4    Fujii, S.5    Fujimori, T.6    Kinoshita, K.7    Honjo, T.8    Chiba, T.9
  • 46
    • 1842609941 scopus 로고    scopus 로고
    • Inhibition of AKT abrogates chemotherapy-induced NF-κB survival mechanisms: implications for therapy in pancreatic cancer
    • Fahy, B. N., Schlieman, M. G., Virudachalam, S., and Bold, R. J. (2004). Inhibition of AKT abrogates chemotherapy-induced NF-κB survival mechanisms: implications for therapy in pancreatic cancer. J. Am. Coll. Surg. 198, 591-599.
    • (2004) J. Am. Coll. Surg. , vol.198 , pp. 591-599
    • Fahy, B.N.1    Schlieman, M.G.2    Virudachalam, S.3    Bold, R.J.4
  • 47
    • 79958119374 scopus 로고    scopus 로고
    • Correlation between tumor-associated proteins and response to neoadjuvant treatment in patients with advanced squamous-cell esophageal cancer
    • Farkas, R., Pozsgai, E., Bellyei, S., Cseke, L., Szigeti, A., Vereczkei, A., Marton, S., Mangel, L., Horvath, O. P., and Papp, A. (2011). Correlation between tumor-associated proteins and response to neoadjuvant treatment in patients with advanced squamous-cell esophageal cancer. Anticancer Res. 31, 1769-1775.
    • (2011) Anticancer Res. , vol.31 , pp. 1769-1775
    • Farkas, R.1    Pozsgai, E.2    Bellyei, S.3    Cseke, L.4    Szigeti, A.5    Vereczkei, A.6    Marton, S.7    Mangel, L.8    Horvath, O.P.9    Papp, A.10
  • 49
    • 0026749295 scopus 로고
    • Unusual expression and localization of heat-shock proteins in human tumor cells
    • Ferrarini, M., Heltai, S., Zocchi, M. R., and Rugarli, C. (1992). Unusual expression and localization of heat-shock proteins in human tumor cells. Int. J. Cancer 51, 613-619.
    • (1992) Int. J. Cancer , vol.51 , pp. 613-619
    • Ferrarini, M.1    Heltai, S.2    Zocchi, M.R.3    Rugarli, C.4
  • 52
    • 0036494443 scopus 로고    scopus 로고
    • Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication
    • Ganss, R., Ryschich, E., Klar, E., Arnold, B., and Hammerling, G. J. (2002). Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. Cancer Res. 62, 1462-1470.
    • (2002) Cancer Res. , vol.62 , pp. 1462-1470
    • Ganss, R.1    Ryschich, E.2    Klar, E.3    Arnold, B.4    Hammerling, G.J.5
  • 53
    • 0035955729 scopus 로고    scopus 로고
    • Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones
    • Garcia-Pineres, A. J., Castro, V., Mora, G., Schmidt, T. J., Strunck, E., Pahl, H. L., and Merfort, I. (2001). Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones. J. Biol. Chem. 276, 39713-39720.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39713-39720
    • Garcia-Pineres, A.J.1    Castro, V.2    Mora, G.3    Schmidt, T.J.4    Strunck, E.5    Pahl, H.L.6    Merfort, I.7
  • 54
    • 28844492580 scopus 로고    scopus 로고
    • Chemosensitization and radiosensitization of tumors by plant polyphenols
    • Garg, A. K., Buchholz, T. A., and Aggarwal, B. B. (2005). Chemosensitization and radiosensitization of tumors by plant polyphenols. Antioxid. Redox Signal. 7, 1630-1647.
    • (2005) Antioxid. Redox Signal. , vol.7 , pp. 1630-1647
    • Garg, A.K.1    Buchholz, T.A.2    Aggarwal, B.B.3
  • 55
    • 44849133308 scopus 로고    scopus 로고
    • Tumor-specific Hsp70 plasma membrane localization is enabled by the glycosphingolipid Gb3
    • doi:10.1371/journal.pone.0001925
    • Gehrmann, M., Liebisch, G., Schmitz, G., Anderson, R., Steinem, C., De Maio, A., Pockley, G., and Multhoff, G. (2008). Tumor-specific Hsp70 plasma membrane localization is enabled by the glycosphingolipid Gb3. PLoS ONE 3, e1925. doi:10.1371/journal.pone.0001925
    • (2008) PLoS ONE , vol.3
    • Gehrmann, M.1    Liebisch, G.2    Schmitz, G.3    Anderson, R.4    Steinem, C.5    De Maio, A.6    Pockley, G.7    Multhoff, G.8
  • 56
  • 59
    • 34548162786 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitor, nimesulide, improves radiation treatment against non-small cell lung cancer both in vitro and in vivo
    • Grimes, K. R., Warren, G. W., Fang, F., Xu, Y., and St. Clair, W. H. (2006). Cyclooxygenase-2 inhibitor, nimesulide, improves radiation treatment against non-small cell lung cancer both in vitro and in vivo. Oncol. Rep. 16, 771-776.
    • (2006) Oncol. Rep. , vol.16 , pp. 771-776
    • Grimes, K.R.1    Warren, G.W.2    Fang, F.3    Xu, Y.4    Clair, S.W.H.5
  • 60
    • 75849117800 scopus 로고    scopus 로고
    • Inflammation and oncogenesis: a vicious connection
    • Grivennikov, S. I., and Karin, M. (2010). Inflammation and oncogenesis: a vicious connection. Curr. Opin. Genet. Dev. 20, 65-71.
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 65-71
    • Grivennikov, S.I.1    Karin, M.2
  • 61
    • 84055190763 scopus 로고    scopus 로고
    • The heat shock proteins as targets for radiosensitization and chemosensitization in cancer
    • Guttmann, D. M., and Koumenis, C. (2011). The heat shock proteins as targets for radiosensitization and chemosensitization in cancer. Cancer Biol. Ther. 12, 1023-1031.
    • (2011) Cancer Biol. Ther. , vol.12 , pp. 1023-1031
    • Guttmann, D.M.1    Koumenis, C.2
  • 62
    • 0038307784 scopus 로고    scopus 로고
    • Immunodeficiency and cancer: prospects for correction
    • Hadden, J. W. (2003). Immunodeficiency and cancer: prospects for correction. Int. Immunopharmacol. 3, 1061-1071.
    • (2003) Int. Immunopharmacol. , vol.3 , pp. 1061-1071
    • Hadden, J.W.1
  • 63
    • 39449085063 scopus 로고    scopus 로고
    • DNA-damage repair; the good, the bad, and the ugly
    • Hakem, R. (2008). DNA-damage repair; the good, the bad, and the ugly. EMBO J. 27, 589-605.
    • (2008) EMBO J. , vol.27 , pp. 589-605
    • Hakem, R.1
  • 64
  • 65
    • 80053355093 scopus 로고    scopus 로고
    • How can we overcome tumor hypoxia in radiation therapy?
    • Harada, H. (2011). How can we overcome tumor hypoxia in radiation therapy? J. Radiat. Res. 52, 545-556.
    • (2011) J. Radiat. Res. , vol.52 , pp. 545-556
    • Harada, H.1
  • 66
    • 64149112403 scopus 로고    scopus 로고
    • The Akt/mTOR pathway assures the synthesis of HIF-1a protein in a glucose-and reoxygenation-dependent manner in irradiated tumors
    • Harada, H., Itasaka, S., Kizaka-Kondoh, S., Shibuya, K., Morinibu, A., Shinomiya, K., and Hiraoka, M. (2009a). The Akt/mTOR pathway assures the synthesis of HIF-1a protein in a glucose-and reoxygenation-dependent manner in irradiated tumors. J. Biol. Chem. 284, 5332-5342.
    • (2009) J. Biol. Chem. , vol.284 , pp. 5332-5342
    • Harada, H.1    Itasaka, S.2    Kizaka-Kondoh, S.3    Shibuya, K.4    Morinibu, A.5    Shinomiya, K.6    Hiraoka, M.7
  • 67
    • 61749090849 scopus 로고    scopus 로고
    • Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation therapy
    • Harada, H., Itasaka, S., Zhu, Y., Zeng, L., Xie, X., Morinibu, A., Shinomiya, K., and Hiraoka, M. (2009b). Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation therapy. Br. J. Cancer 100, 747-757.
    • (2009) Br. J. Cancer , vol.100 , pp. 747-757
    • Harada, H.1    Itasaka, S.2    Zhu, Y.3    Zeng, L.4    Xie, X.5    Morinibu, A.6    Shinomiya, K.7    Hiraoka, M.8
  • 68
    • 84860835752 scopus 로고    scopus 로고
    • (-)-Epigallocatechin-3-gallate, a green tea-derived catechin, synergizes with celecoxib to inhibit IL-1-induced tumorigenic mediators by human pancreatic adenocarcinoma cells Colo357
    • Härdtner, C., Multhoff, G., Falk, W., and Radons, J. (2012). (-)-Epigallocatechin-3-gallate, a green tea-derived catechin, synergizes with celecoxib to inhibit IL-1-induced tumorigenic mediators by human pancreatic adenocarcinoma cells Colo357. Eur. J. Pharmacol. 684, 36-43.
    • (2012) Eur. J. Pharmacol. , vol.684 , pp. 36-43
    • Härdtner, C.1    Multhoff, G.2    Falk, W.3    Radons, J.4
  • 69
    • 61949193344 scopus 로고    scopus 로고
    • Modification of the cysteine residues in IκBα kinase and NF-κB (p65) by xanthohumol leads to suppression of NF-κB-regulated gene products and potentiation of apoptosis in leukemia cells
    • Harikumar, K. B., Kunnumakkara, A. B., Ahn, K. S., Anand, P., Krishnan, S., Guha, S., and Aggarwal, B. B. (2009). Modification of the cysteine residues in IκBα kinase and NF-κB (p65) by xanthohumol leads to suppression of NF-κB-regulated gene products and potentiation of apoptosis in leukemia cells. Blood 113, 2003-2013.
    • (2009) Blood , vol.113 , pp. 2003-2013
    • Harikumar, K.B.1    Kunnumakkara, A.B.2    Ahn, K.S.3    Anand, P.4    Krishnan, S.5    Guha, S.6    Aggarwal, B.B.7
  • 70
    • 0018915706 scopus 로고
    • Cancer of the breast: the past decade (first of two parts)
    • Henderson, I. C., and Canellos, G. P. (1980a). Cancer of the breast: the past decade (first of two parts). N. Engl. J. Med. 302, 17-30.
    • (1980) N. Engl. J. Med. , vol.302 , pp. 17-30
    • Henderson, I.C.1    Canellos, G.P.2
  • 71
    • 0018913135 scopus 로고
    • Cancer of the breast: the past decade (second of two parts)
    • Henderson, I. C., and Canellos, G. P. (1980b). Cancer of the breast: the past decade (second of two parts). N. Engl. J. Med. 302, 78-90.
    • (1980) N. Engl. J. Med. , vol.302 , pp. 78-90
    • Henderson, I.C.1    Canellos, G.P.2
  • 72
    • 0014518510 scopus 로고
    • Changes of cell proliferation characteristics in a rat rhabdomyosarcoma before and after x-irradiation
    • Hermens, A. F., and Barendsen, G. W. (1969). Changes of cell proliferation characteristics in a rat rhabdomyosarcoma before and after x-irradiation. Eur. J. Cancer 5, 173-189.
    • (1969) Eur. J. Cancer , vol.5 , pp. 173-189
    • Hermens, A.F.1    Barendsen, G.W.2
  • 73
    • 0024541931 scopus 로고
    • Selective release from cultured mammalian cells of heat-shock (stress) proteins that resemble glia-axon transfer proteins
    • Hightower, L. E., and Guidon, P. T. Jr. (1989). Selective release from cultured mammalian cells of heat-shock (stress) proteins that resemble glia-axon transfer proteins. J. Cell. Physiol. 138, 257-266.
    • (1989) J. Cell. Physiol. , vol.138 , pp. 257-266
    • Hightower, L.E.1    Guidon Jr., P.T.2
  • 74
    • 14844288915 scopus 로고    scopus 로고
    • The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists
    • Hodgson, M. C., Astapova, I., Cheng, S., Lee, L. J., Verhoeven, M. C., Choi, E., Balk, S. P., and Hollenberg, A. N. (2005). The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists. J. Biol. Chem. 280, 6511-6519.
    • (2005) J. Biol. Chem. , vol.280 , pp. 6511-6519
    • Hodgson, M.C.1    Astapova, I.2    Cheng, S.3    Lee, L.J.4    Verhoeven, M.C.5    Choi, E.6    Balk, S.P.7    Hollenberg, A.N.8
  • 76
    • 46149125267 scopus 로고    scopus 로고
    • Membrane-associated stress proteins: more than simply chaperones
    • Horvath, I., Multhoff, G., Sonnleitner, A., and Vigh, L. (2008). Membrane-associated stress proteins: more than simply chaperones. Biochim. Biophys. Acta 1778, 1653-1664.
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 1653-1664
    • Horvath, I.1    Multhoff, G.2    Sonnleitner, A.3    Vigh, L.4
  • 77
    • 75749139400 scopus 로고    scopus 로고
    • Cell biology: stability in times of stress
    • Horvath, I., and Vigh, L. (2010). Cell biology: stability in times of stress. Nature 463, 436-438.
    • (2010) Nature , vol.463 , pp. 436-438
    • Horvath, I.1    Vigh, L.2
  • 79
    • 45349099696 scopus 로고    scopus 로고
    • Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: the mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1
    • Huang, X. Z., Wang, J., Huang, C., Chen, Y. Y., Shi, G. Y., Hu, Q. S., and Yi, J. (2008). Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: the mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1. Cancer Biol. Ther. 7, 468-475.
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 468-475
    • Huang, X.Z.1    Wang, J.2    Huang, C.3    Chen, Y.Y.4    Shi, G.Y.5    Hu, Q.S.6    Yi, J.7
  • 80
    • 0040298568 scopus 로고    scopus 로고
    • Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
    • Jänicke, R. U., Sprengart, M. L., Wati, M. R., and Porter, A. G. (1998). Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 273, 9357-9360.
    • (1998) J. Biol. Chem. , vol.273 , pp. 9357-9360
    • Jänicke, R.U.1    Sprengart, M.L.2    Wati, M.R.3    Porter, A.G.4
  • 81
    • 44149095198 scopus 로고    scopus 로고
    • Radiosensitization of melanoma cells through combined inhibition of protein regulators of cell survival
    • Johnson, G. E., Ivanov, V. N., and Hei, T. K. (2008). Radiosensitization of melanoma cells through combined inhibition of protein regulators of cell survival. Apoptosis 13, 790-802.
    • (2008) Apoptosis , vol.13 , pp. 790-802
    • Johnson, G.E.1    Ivanov, V.N.2    Hei, T.K.3
  • 82
    • 0347334750 scopus 로고    scopus 로고
    • IL-1β-mediated up-regulation of HIF-1α via an NFκB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis
    • Jung, Y. J., Isaacs, J. S., Lee, S., Trepel, J., and Neckers, L. (2003). IL-1β-mediated up-regulation of HIF-1α via an NFκB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J. 17, 2115-2117.
    • (2003) FASEB J. , vol.17 , pp. 2115-2117
    • Jung, Y.J.1    Isaacs, J.S.2    Lee, S.3    Trepel, J.4    Neckers, L.5
  • 83
    • 43649093915 scopus 로고    scopus 로고
    • Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway
    • Kaelin, W. G. Jr., and Ratcliffe, P. J. (2008). Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol. Cell 30, 393-402.
    • (2008) Mol. Cell , vol.30 , pp. 393-402
    • Kaelin Jr., W.G.1    Ratcliffe, P.J.2
  • 84
    • 34547114987 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol-3-OH kinase/Akt signaling impairs DNA repair in glioblastoma cells following ionizing radiation
    • Kao, G. D., Jiang, Z., Fernandes, A. M., Gupta, A. K., and Maity, A. (2007). Inhibition of phosphatidylinositol-3-OH kinase/Akt signaling impairs DNA repair in glioblastoma cells following ionizing radiation. J. Biol. Chem. 282, 21206-21212.
    • (2007) J. Biol. Chem. , vol.282 , pp. 21206-21212
    • Kao, G.D.1    Jiang, Z.2    Fernandes, A.M.3    Gupta, A.K.4    Maity, A.5
  • 85
    • 0037022534 scopus 로고    scopus 로고
    • Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants
    • Karanjawala, Z. E., Murphy, N., Hinton, D. R., Hsieh, C. L., and Lieber, M. R. (2002). Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Curr. Biol. 12, 397-402.
    • (2002) Curr. Biol. , vol.12 , pp. 397-402
    • Karanjawala, Z.E.1    Murphy, N.2    Hinton, D.R.3    Hsieh, C.L.4    Lieber, M.R.5
  • 86
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-κB in cancer development and progression
    • Karin, M. (2006). Nuclear factor-κB in cancer development and progression. Nature 441, 431-436.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 87
    • 32944474237 scopus 로고    scopus 로고
    • Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer
    • Karin, M., Lawrence, T., and Nizet, V. (2006). Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 124, 823-835.
    • (2006) Cell , vol.124 , pp. 823-835
    • Karin, M.1    Lawrence, T.2    Nizet, V.3
  • 88
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai, T., and Akira, S. (2011). Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34, 637-650.
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 89
    • 33845228341 scopus 로고    scopus 로고
    • Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of survivin following irradiation
    • Kim, K. W., Mutter, R. W., Cao, C., Albert, J. M., Shinohara, E. T., Sekhar, K. R., and Lu, B. (2006a). Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of survivin following irradiation. Mol. Cancer Ther. 5, 2659-2665.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 2659-2665
    • Kim, K.W.1    Mutter, R.W.2    Cao, C.3    Albert, J.M.4    Shinohara, E.T.5    Sekhar, K.R.6    Lu, B.7
  • 90
    • 33745258657 scopus 로고    scopus 로고
    • Tumor-driven evolution of immunosuppressive networks during malignant progression
    • Kim, R., Emi, M., Tanabe, K., and Arihiro, K. (2006b). Tumor-driven evolution of immunosuppressive networks during malignant progression. Cancer Res. 66, 5527-5536.
    • (2006) Cancer Res. , vol.66 , pp. 5527-5536
    • Kim, R.1    Emi, M.2    Tanabe, K.3    Arihiro, K.4
  • 91
    • 60549083336 scopus 로고    scopus 로고
    • Targeting heat shock protein 90 overrides the resistance of lung cancer cells by blocking radiation-induced stabilization of hypoxia-inducible factor-1a
    • Kim, W. Y., Oh, S. H., Woo, J. K., Hong, W. K., and Lee, H. Y. (2009). Targeting heat shock protein 90 overrides the resistance of lung cancer cells by blocking radiation-induced stabilization of hypoxia-inducible factor-1a. Cancer Res. 69, 1624-1632.
    • (2009) Cancer Res. , vol.69 , pp. 1624-1632
    • Kim, W.Y.1    Oh, S.H.2    Woo, J.K.3    Hong, W.K.4    Lee, H.Y.5
  • 92
    • 15244344206 scopus 로고    scopus 로고
    • HIF-1a induces genetic instability by transcriptionally downregulating MutSalpha expression
    • Koshiji, M., To, K. K., Hammer, S., Kumamoto, K., Harris, A. L., Modrich, P., and Huang, L. E. (2005). HIF-1a induces genetic instability by transcriptionally downregulating MutSalpha expression. Mol. Cell 17, 793-803.
    • (2005) Mol. Cell , vol.17 , pp. 793-803
    • Koshiji, M.1    To, K.K.2    Hammer, S.3    Kumamoto, K.4    Harris, A.L.5    Modrich, P.6    Huang, L.E.7
  • 93
    • 34548301757 scopus 로고    scopus 로고
    • Radiosensitization of human glioma cells by cyclooxygenase-2 (COX-2) inhibition: independent on COX-2 expression and dependent on the COX-2 inhibitor and sequence of administration
    • Kuipers, G. K., Slotman, B. J., Wedekind, L. E., Stoter, T. R., Berg, J., Sminia, P., and Lafleur, M. V. (2007). Radiosensitization of human glioma cells by cyclooxygenase-2 (COX-2) inhibition: independent on COX-2 expression and dependent on the COX-2 inhibitor and sequence of administration. Int. J. Radiat. Biol. 83, 677-685.
    • (2007) Int. J. Radiat. Biol. , vol.83 , pp. 677-685
    • Kuipers, G.K.1    Slotman, B.J.2    Wedekind, L.E.3    Stoter, T.R.4    Berg, J.5    Sminia, P.6    Lafleur, M.V.7
  • 94
    • 47849098044 scopus 로고    scopus 로고
    • Inflammation: gearing the journey to cancer
    • Kundu, J. K., and Surh, Y. J. (2008). Inflammation: gearing the journey to cancer. Mutat. Res. 659, 15-30.
    • (2008) Mutat. Res. , vol.659 , pp. 15-30
    • Kundu, J.K.1    Surh, Y.J.2
  • 95
    • 42249102138 scopus 로고    scopus 로고
    • Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-κB-regulated gene products
    • Kunnumakkara, A. B., Diagaradjane, P., Guha, S., Deorukhkar, A., Shentu, S., Aggarwal, B. B., and Krishnan, S. (2008). Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-κB-regulated gene products. Clin. Cancer Res. 14, 2128-2136.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 2128-2136
    • Kunnumakkara, A.B.1    Diagaradjane, P.2    Guha, S.3    Deorukhkar, A.4    Shentu, S.5    Aggarwal, B.B.6    Krishnan, S.7
  • 97
    • 0037273848 scopus 로고    scopus 로고
    • Apo2L/TRAIL and its death and decoy receptors
    • LeBlanc, H. N., and Ashkenazi, A. (2003). Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ. 10, 66-75.
    • (2003) Cell Death Differ. , vol.10 , pp. 66-75
    • LeBlanc, H.N.1    Ashkenazi, A.2
  • 99
    • 77649341172 scopus 로고    scopus 로고
    • Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy
    • Li, F., and Sethi, G. (2010). Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy. Biochim. Biophys. Acta 1805, 167-180.
    • (2010) Biochim. Biophys. Acta , vol.1805 , pp. 167-180
    • Li, F.1    Sethi, G.2
  • 100
    • 34248141100 scopus 로고    scopus 로고
    • A cytokine-mediated link between innate immunity, inflammation, and cancer
    • Lin, W. W., and Karin, M. (2007). A cytokine-mediated link between innate immunity, inflammation, and cancer. J. Clin. Invest. 117, 1175-1183.
    • (2007) J. Clin. Invest. , vol.117 , pp. 1175-1183
    • Lin, W.W.1    Karin, M.2
  • 101
    • 77953360484 scopus 로고    scopus 로고
    • HIF-1 and NDRG2 contribute to hypoxia-induced radioresistance of cervical cancer Hela cells
    • Liu, J., Zhang, J., Wang, X., Li, Y., Chen, Y., Li, K., Zhang, J., Yao, L., and Guo, G. (2010). HIF-1 and NDRG2 contribute to hypoxia-induced radioresistance of cervical cancer Hela cells. Exp. Cell Res. 316, 1985-1993.
    • (2010) Exp. Cell Res. , vol.316 , pp. 1985-1993
    • Liu, J.1    Zhang, J.2    Wang, X.3    Li, Y.4    Chen, Y.5    Li, K.6    Zhang, J.7    Yao, L.8    Guo, G.9
  • 102
    • 84857922731 scopus 로고    scopus 로고
    • Three-dimensional conformal radiotherapy in prostate cancer patients: rise in interleukin 6 (IL-6) but not IL-2, IL-4, IL-5, tumor necrosis factor-a, MIP-1-a, and LIF levels
    • Lopes, C. O., and Callera, F. (2011). Three-dimensional conformal radiotherapy in prostate cancer patients: rise in interleukin 6 (IL-6) but not IL-2, IL-4, IL-5, tumor necrosis factor-a, MIP-1-a, and LIF levels. Int. J. Radiat. Oncol. Biol. Phys. 82, 1385-1388.
    • (2011) Int. J. Radiat. Oncol. Biol. Phys. , vol.82 , pp. 1385-1388
    • Lopes, C.O.1    Callera, F.2
  • 103
    • 30044447736 scopus 로고    scopus 로고
    • Immune cell migration in inflammation: present and future therapeutic targets
    • Luster, A. D., Alon, R., and von Andrian, U. H. (2005). Immune cell migration in inflammation: present and future therapeutic targets. Nat. Immunol. 6, 1182-1190.
    • (2005) Nat. Immunol. , vol.6 , pp. 1182-1190
    • Luster, A.D.1    Alon, R.2    von Andrian, U.H.3
  • 104
    • 29844445035 scopus 로고    scopus 로고
    • NF-κB modulation and ionizing radiation: mechanisms and future directions for cancer treatment
    • Magne, N., Toillon, R. A., Bottero, V., Didelot, C., Houtte, P. V., Gerard, J. P., and Peyron, J. F. (2006). NF-κB modulation and ionizing radiation: mechanisms and future directions for cancer treatment. Cancer Lett. 231, 158-168.
    • (2006) Cancer Lett. , vol.231 , pp. 158-168
    • Magne, N.1    Toillon, R.A.2    Bottero, V.3    Didelot, C.4    Houtte, P.V.5    Gerard, J.P.6    Peyron, J.F.7
  • 106
    • 0035989680 scopus 로고    scopus 로고
    • HSP90 as a new therapeutic target for cancer therapy: the story unfolds
    • Maloney, A., and Workman, P. (2002). HSP90 as a new therapeutic target for cancer therapy: the story unfolds. Expert. Opin. Biol. Ther. 2, 3-24.
    • (2002) Expert. Opin. Biol. Ther. , vol.2 , pp. 3-24
    • Maloney, A.1    Workman, P.2
  • 109
    • 0037135630 scopus 로고    scopus 로고
    • Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor
    • Masiello, D., Cheng, S., Bubley, G. J., Lu, M. L., and Balk, S. P. (2002). Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor. J. Biol. Chem. 277, 26321-26326.
    • (2002) J. Biol. Chem. , vol.277 , pp. 26321-26326
    • Masiello, D.1    Cheng, S.2    Bubley, G.J.3    Lu, M.L.4    Balk, S.P.5
  • 110
    • 0032191916 scopus 로고    scopus 로고
    • An innate sense of danger
    • Matzinger, P. (1998). An innate sense of danger. Semin. Immunol. 10, 399-415.
    • (1998) Semin. Immunol. , vol.10 , pp. 399-415
    • Matzinger, P.1
  • 111
    • 0034808951 scopus 로고    scopus 로고
    • UVA radiation stimulates ceramide production: relationship to oxidative stress and potential role in ERK, JNK, and p38 activation
    • Maziere, C., Conte, M. A., Leborgne, L., Levade, T., Hornebeck, W., Santus, R., and Maziere, J. C. (2001). UVA radiation stimulates ceramide production: relationship to oxidative stress and potential role in ERK, JNK, and p38 activation. Biochem. Biophys. Res. Commun. 281, 289-294.
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , pp. 289-294
    • Maziere, C.1    Conte, M.A.2    Leborgne, L.3    Levade, T.4    Hornebeck, W.5    Santus, R.6    Maziere, J.C.7
  • 112
    • 77949881048 scopus 로고    scopus 로고
    • Cytokines levels, severity of acute mucositis and the need of PEG tube installation during chemo-radiation for head and neck cancer-a prospective pilot study
    • Meirovitz, A., Kuten, M., Billan, S., Abdah-Bortnyak, R., Sharon, A., Peretz, T., Sela, M., Schaffer, M., and Barak, V. (2010). Cytokines levels, severity of acute mucositis and the need of PEG tube installation during chemo-radiation for head and neck cancer-a prospective pilot study. Radiat. Oncol. 5, 16.
    • (2010) Radiat. Oncol. , vol.5 , pp. 16
    • Meirovitz, A.1    Kuten, M.2    Billan, S.3    Abdah-Bortnyak, R.4    Sharon, A.5    Peretz, T.6    Sela, M.7    Schaffer, M.8    Barak, V.9
  • 113
    • 66349110620 scopus 로고    scopus 로고
    • Toll-like receptors as targets in chronic liver diseases
    • Mencin, A., Kluwe, J., and Schwabe, R. F. (2009). Toll-like receptors as targets in chronic liver diseases. Gut 58, 704-720.
    • (2009) Gut , vol.58 , pp. 704-720
    • Mencin, A.1    Kluwe, J.2    Schwabe, R.F.3
  • 115
    • 77952010566 scopus 로고    scopus 로고
    • Ad.Egr-TNF and local ionizing radiation suppress metastases by interferon-β-dependent activation of antigen-specific CD8+ T cells
    • Meng, Y., Mauceri, H. J., Khodarev, N. N., Darga, T. E., Pitroda, S. P., Beckett, M. A., Kufe, D. W., and Weichselbaum, R. R. (2010). Ad.Egr-TNF and local ionizing radiation suppress metastases by interferon-β-dependent activation of antigen-specific CD8+ T cells. Mol. Ther. 18, 912-920.
    • (2010) Mol. Ther. , vol.18 , pp. 912-920
    • Meng, Y.1    Mauceri, H.J.2    Khodarev, N.N.3    Darga, T.E.4    Pitroda, S.P.5    Beckett, M.A.6    Kufe, D.W.7    Weichselbaum, R.R.8
  • 116
    • 33847013757 scopus 로고    scopus 로고
    • c-MYC delays prometaphase by direct transactivation of MAD2 and BubR1: identification of mechanisms underlying c-MYC-induced DNA damage and chromosomal instability
    • Menssen, A., Epanchintsev, A., Lodygin, D., Rezaei, N., Jung, P., Verdoodt, B., Diebold, J., and Hermeking, H. (2007). c-MYC delays prometaphase by direct transactivation of MAD2 and BubR1: identification of mechanisms underlying c-MYC-induced DNA damage and chromosomal instability. Cell Cycle 6, 339-352.
    • (2007) Cell Cycle , vol.6 , pp. 339-352
    • Menssen, A.1    Epanchintsev, A.2    Lodygin, D.3    Rezaei, N.4    Jung, P.5    Verdoodt, B.6    Diebold, J.7    Hermeking, H.8
  • 117
    • 0037660900 scopus 로고    scopus 로고
    • The role of DNA breaks in genomic instability and tumorigenesis
    • Mills, K. D., Ferguson, D. O., and Alt, F. W. (2003). The role of DNA breaks in genomic instability and tumorigenesis. Immunol. Rev. 194, 77-95.
    • (2003) Immunol. Rev. , vol.194 , pp. 77-95
    • Mills, K.D.1    Ferguson, D.O.2    Alt, F.W.3
  • 118
    • 0028071612 scopus 로고
    • Murine B cell proliferation and protection from apoptosis with an antibody against a 105-kD molecule: unresponsiveness of X-linked immunodeficient B cells
    • Miyake, K., Yamashita, Y., Hitoshi, Y., Takatsu, K., and Kimoto, M. (1994). Murine B cell proliferation and protection from apoptosis with an antibody against a 105-kD molecule: unresponsiveness of X-linked immunodeficient B cells. J. Exp. Med. 180, 1217-1224.
    • (1994) J. Exp. Med. , vol.180 , pp. 1217-1224
    • Miyake, K.1    Yamashita, Y.2    Hitoshi, Y.3    Takatsu, K.4    Kimoto, M.5
  • 119
    • 0028949390 scopus 로고
    • RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family
    • Miyake, K., Yamashita, Y., Ogata, M., Sudo, T., and Kimoto, M. (1995). RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. J. Immunol. 154, 3333-3340.
    • (1995) J. Immunol. , vol.154 , pp. 3333-3340
    • Miyake, K.1    Yamashita, Y.2    Ogata, M.3    Sudo, T.4    Kimoto, M.5
  • 120
    • 2342611976 scopus 로고    scopus 로고
    • Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules
    • Moeller, B. J., Cao, Y., Li, C. Y., and Dewhirst, M. W. (2004). Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules. Cancer Cell 5, 429-441.
    • (2004) Cancer Cell , vol.5 , pp. 429-441
    • Moeller, B.J.1    Cao, Y.2    Li, C.Y.3    Dewhirst, M.W.4
  • 121
    • 33745517944 scopus 로고    scopus 로고
    • HIF-1 and tumour radiosensitivity
    • Moeller, B. J., and Dewhirst, M. W. (2006). HIF-1 and tumour radiosensitivity. Br. J. Cancer 95, 1-5.
    • (2006) Br. J. Cancer , vol.95 , pp. 1-5
    • Moeller, B.J.1    Dewhirst, M.W.2
  • 125
    • 34848859541 scopus 로고    scopus 로고
    • Heat shock protein 70 (Hsp70): membrane location, export and immunological relevance
    • Multhoff, G. (2007). Heat shock protein 70 (Hsp70): membrane location, export and immunological relevance. Methods 43, 229-237.
    • (2007) Methods , vol.43 , pp. 229-237
    • Multhoff, G.1
  • 126
    • 0028953056 scopus 로고
    • A stress-inducible 72-kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells
    • Multhoff, G., Botzler, C., Wiesnet, M., Müller, E., Meier, T., Wilmanns, W., and Issels, R. D. (1995). A stress-inducible 72-kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells. Int. J. Cancer 61, 272-279.
    • (1995) Int. J. Cancer , vol.61 , pp. 272-279
    • Multhoff, G.1    Botzler, C.2    Wiesnet, M.3    Müller, E.4    Meier, T.5    Wilmanns, W.6    Issels, R.D.7
  • 127
    • 0030224714 scopus 로고    scopus 로고
    • Cell surface expression of heat shock proteins and the immune response
    • Multhoff, G., and Hightower, L. E. (1996). Cell surface expression of heat shock proteins and the immune response. Cell Stress Chaperones 1, 167-176.
    • (1996) Cell Stress Chaperones , vol.1 , pp. 167-176
    • Multhoff, G.1    Hightower, L.E.2
  • 128
    • 84863601838 scopus 로고    scopus 로고
    • Chronic inflammation in cancer development
    • doi:10.3389/fimmu.2011.00098
    • Multhoff, G., Molls, M., and Radons, J. (2012). Chronic inflammation in cancer development. Front. Immunol. 2:98. doi:10.3389/fimmu.2011.00098
    • (2012) Front. Immunol. , vol.2 , pp. 98
    • Multhoff, G.1    Molls, M.2    Radons, J.3
  • 131
    • 80053587355 scopus 로고    scopus 로고
    • Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy
    • Nambiar, D., Rajamani, P., and Singh, R. P. (2011). Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy. Mutat. Res. 728, 139-157.
    • (2011) Mutat. Res. , vol.728 , pp. 139-157
    • Nambiar, D.1    Rajamani, P.2    Singh, R.P.3
  • 132
    • 34447327216 scopus 로고    scopus 로고
    • Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
    • Naugler, W. E., Sakurai, T., Kim, S., Maeda, S., Kim, K., Elsharkawy, A. M., and Karin, M. (2007). Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317, 121-124.
    • (2007) Science , vol.317 , pp. 121-124
    • Naugler, W.E.1    Sakurai, T.2    Kim, S.3    Maeda, S.4    Kim, K.5    Elsharkawy, A.M.6    Karin, M.7
  • 133
    • 55849145075 scopus 로고    scopus 로고
    • Unconventional mechanisms of protein transport to the cell surface of eukaryotic cells
    • Nickel, W., and Seedorf, M. (2008). Unconventional mechanisms of protein transport to the cell surface of eukaryotic cells. Annu. Rev. Cell Dev. Biol. 24, 287-308.
    • (2008) Annu. Rev. Cell Dev. Biol. , vol.24 , pp. 287-308
    • Nickel, W.1    Seedorf, M.2
  • 134
    • 0021247642 scopus 로고
    • Gamma-irradiation facilitates the expression of adoptive immunity against established tumors by eliminating suppressor T cells
    • North, R. J. (1984). Gamma-irradiation facilitates the expression of adoptive immunity against established tumors by eliminating suppressor T cells. Cancer Immunol. Immunother. 16, 175-181.
    • (1984) Cancer Immunol. Immunother. , vol.16 , pp. 175-181
    • North, R.J.1
  • 136
  • 137
    • 84855172987 scopus 로고    scopus 로고
    • Toll-like receptor 4 activation in cancer progression and therapy
    • Oblak, A., and Jerala, R. (2011). Toll-like receptor 4 activation in cancer progression and therapy. Clin. Dev. Immunol. 2011, 609579.
    • (2011) Clin. Dev. Immunol. , vol.2011 , pp. 609579
    • Oblak, A.1    Jerala, R.2
  • 138
    • 80054851136 scopus 로고    scopus 로고
    • Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family
    • Ohto, U., Miyake, K., and Shimizu, T. (2011). Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family. J. Mol. Biol. 413, 815-825.
    • (2011) J. Mol. Biol. , vol.413 , pp. 815-825
    • Ohto, U.1    Miyake, K.2    Shimizu, T.3
  • 139
    • 34547125342 scopus 로고    scopus 로고
    • Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-κB and NF-κB-regulated gene expression through direct inhibition of IκBa kinase β on cysteine 179 residue
    • Pandey, M. K., Sandur, S. K., Sung, B., Sethi, G., Kunnumakkara, A. B., and Aggarwal, B. B. (2007). Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-κB and NF-κB-regulated gene expression through direct inhibition of IκBa kinase β on cysteine 179 residue. J. Biol. Chem. 282, 17340-17350.
    • (2007) J. Biol. Chem. , vol.282 , pp. 17340-17350
    • Pandey, M.K.1    Sandur, S.K.2    Sung, B.3    Sethi, G.4    Kunnumakkara, A.B.5    Aggarwal, B.B.6
  • 140
    • 48549105216 scopus 로고    scopus 로고
    • Berberine modifies cysteine 179 of IκBa kinase, suppresses nuclear factor-κB-regulated antiapoptotic gene products, and potentiates apoptosis
    • Pandey, M. K., Sung, B., Kunnumakkara, A. B., Sethi, G., Chaturvedi, M. M., and Aggarwal, B. B. (2008). Berberine modifies cysteine 179 of IκBa kinase, suppresses nuclear factor-κB-regulated antiapoptotic gene products, and potentiates apoptosis. Cancer Res. 68, 5370-5379.
    • (2008) Cancer Res. , vol.68 , pp. 5370-5379
    • Pandey, M.K.1    Sung, B.2    Kunnumakkara, A.B.3    Sethi, G.4    Chaturvedi, M.M.5    Aggarwal, B.B.6
  • 142
    • 77955792960 scopus 로고    scopus 로고
    • IL-8 and IL-6 bystander signalling in human glioblastoma cells exposed to gamma radiation
    • Pasi, F., Facoetti, A., and Nano, R. (2010). IL-8 and IL-6 bystander signalling in human glioblastoma cells exposed to gamma radiation. Anticancer Res. 30, 2769-2772.
    • (2010) Anticancer Res. , vol.30 , pp. 2769-2772
    • Pasi, F.1    Facoetti, A.2    Nano, R.3
  • 144
    • 32244439530 scopus 로고    scopus 로고
    • Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation
    • Pickering, M. T., and Kowalik, T. F. (2006). Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation. Oncogene 25, 746-755.
    • (2006) Oncogene , vol.25 , pp. 746-755
    • Pickering, M.T.1    Kowalik, T.F.2
  • 145
    • 51649087754 scopus 로고    scopus 로고
    • JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders
    • Plo, I., Nakatake, M., Malivert, L., de Villartay, J. P., Giraudier, S., Villeval, J. L., Wiesmuller, L., and Vainchenker, W. (2008). JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders. Blood 112, 1402-1412.
    • (2008) Blood , vol.112 , pp. 1402-1412
    • Plo, I.1    Nakatake, M.2    Malivert, L.3    de Villartay, J.P.4    Giraudier, S.5    Villeval, J.L.6    Wiesmuller, L.7    Vainchenker, W.8
  • 146
    • 52449125973 scopus 로고    scopus 로고
    • Cell stress proteins in extracellular fluids: friend or foe?
    • Pockley, A. G., and Multhoff, G. (2008). Cell stress proteins in extracellular fluids: friend or foe? Novartis Found. Symp. 291, 86-95.
    • (2008) Novartis Found. Symp. , vol.291 , pp. 86-95
    • Pockley, A.G.1    Multhoff, G.2
  • 148
    • 77956246885 scopus 로고    scopus 로고
    • Crotepoxide chemosensitizes tumor cells through inhibition of expression of proliferation, invasion, and angiogenic proteins linked to proinflammatory pathway
    • Prasad, S., Yadav, V. R., Sundaram, C., Reuter, S., Hema, P. S., Nair, M. S., Chaturvedi, M. M., and Aggarwal, B. B. (2010). Crotepoxide chemosensitizes tumor cells through inhibition of expression of proliferation, invasion, and angiogenic proteins linked to proinflammatory pathway. J. Biol. Chem. 285, 26987-26997.
    • (2010) J. Biol. Chem. , vol.285 , pp. 26987-26997
    • Prasad, S.1    Yadav, V.R.2    Sundaram, C.3    Reuter, S.4    Hema, P.S.5    Nair, M.S.6    Chaturvedi, M.M.7    Aggarwal, B.B.8
  • 149
    • 0031444238 scopus 로고    scopus 로고
    • Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
    • Prodromou, C., Roe, S. M., O'Brien, R., Ladbury, J. E., Piper, P. W., and Pearl, L. H. (1997). Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone. Cell 90, 65-75.
    • (1997) Cell , vol.90 , pp. 65-75
    • Prodromou, C.1    Roe, S.M.2    O'Brien, R.3    Ladbury, J.E.4    Piper, P.W.5    Pearl, L.H.6
  • 150
    • 84861804643 scopus 로고    scopus 로고
    • Curcumin improves the antitumor effect of X-ray irradiation by blocking the NF-κB pathway: an in-vitro study of lymphoma
    • doi:10.1097/CAD.0b013e3283503fbc. [Epub ahead of print].
    • Qiao, Q., Jiang, Y., and Li, G. (2012). Curcumin improves the antitumor effect of X-ray irradiation by blocking the NF-κB pathway: an in-vitro study of lymphoma. Anticancer Drugs. doi:10.1097/CAD.0b013e3283503fbc. [Epub ahead of print].
    • (2012) Anticancer Drugs
    • Qiao, Q.1    Jiang, Y.2    Li, G.3
  • 151
    • 33646727546 scopus 로고    scopus 로고
    • Genistein inhibits radiation-induced activation of NF-κB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest
    • doi:10.1186/1471-2407-6-107
    • Raffoul, J. J., Wang, Y., Kucuk, O., Forman, J. D., Sarkar, F. H., and Hillman, G. G. (2006). Genistein inhibits radiation-induced activation of NF-κB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest. BMC Cancer 6, 107. doi:10.1186/1471-2407-6-107
    • (2006) BMC Cancer , vol.6 , pp. 107
    • Raffoul, J.J.1    Wang, Y.2    Kucuk, O.3    Forman, J.D.4    Sarkar, F.H.5    Hillman, G.G.6
  • 153
    • 24944579985 scopus 로고    scopus 로고
    • Inhibition of DNA repair as a mechanism of enhanced radioresponse of head and neck carcinoma cells by a selective cyclooxygenase-2 inhibitor, celecoxib
    • Raju, U., Ariga, H., Dittmann, K., Nakata, E., Ang, K. K., and Milas, L. (2005). Inhibition of DNA repair as a mechanism of enhanced radioresponse of head and neck carcinoma cells by a selective cyclooxygenase-2 inhibitor, celecoxib. Int. J. Radiat. Oncol. Biol. Phys. 63, 520-528.
    • (2005) Int. J. Radiat. Oncol. Biol. Phys. , vol.63 , pp. 520-528
    • Raju, U.1    Ariga, H.2    Dittmann, K.3    Nakata, E.4    Ang, K.K.5    Milas, L.6
  • 155
    • 78149493021 scopus 로고    scopus 로고
    • The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation
    • Rudner, J., Ruiner, C. E., Handrick, R., Eibl, H. J., Belka, C., and Jendrossek, V. (2010). The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation. Radiat. Oncol. 5, 108.
    • (2010) Radiat. Oncol. , vol.5 , pp. 108
    • Rudner, J.1    Ruiner, C.E.2    Handrick, R.3    Eibl, H.J.4    Belka, C.5    Jendrossek, V.6
  • 156
    • 79251474762 scopus 로고    scopus 로고
    • KNK437, a benzylidene lactam compound, sensitises prostate cancer cells to the apoptotic effect of hyperthermia
    • Sahin, E., Sahin, M., Sanlioglu, A. D., and Gumuslu, S. (2011). KNK437, a benzylidene lactam compound, sensitises prostate cancer cells to the apoptotic effect of hyperthermia. Int. J. Hyperthermia 27, 63-73.
    • (2011) Int. J. Hyperthermia , vol.27 , pp. 63-73
    • Sahin, E.1    Sahin, M.2    Sanlioglu, A.D.3    Gumuslu, S.4
  • 157
    • 0035873741 scopus 로고    scopus 로고
    • A novel role for the Bcl-2 protein family: specific suppression of the RAD51 recombination pathway
    • Saintigny, Y., Dumay, A., Lambert, S., and Lopez, B. S. (2001). A novel role for the Bcl-2 protein family: specific suppression of the RAD51 recombination pathway. EMBO J. 20, 2596-2607.
    • (2001) EMBO J. , vol.20 , pp. 2596-2607
    • Saintigny, Y.1    Dumay, A.2    Lambert, S.3    Lopez, B.S.4
  • 158
    • 0034638623 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway
    • Sandau, K. B., Faus, H. G., and Brune, B. (2000). Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway. Biochem. Biophys. Res. Commun. 278, 263-267.
    • (2000) Biochem. Biophys. Res. Commun. , vol.278 , pp. 263-267
    • Sandau, K.B.1    Faus, H.G.2    Brune, B.3
  • 160
    • 77950254153 scopus 로고    scopus 로고
    • Links between innate immunity and normal tissue radiobiology
    • Schaue, D., and McBride, W. H. (2010). Links between innate immunity and normal tissue radiobiology. Radiat. Res. 173, 406-417.
    • (2010) Radiat. Res. , vol.173 , pp. 406-417
    • Schaue, D.1    McBride, W.H.2
  • 161
    • 80655127833 scopus 로고    scopus 로고
    • Radiation combined with hyperthermia induces HSP70-dependent maturation of dendritic cells and release of pro-inflammatory cytokines by dendritic cells and macrophages
    • Schildkopf, P., Frey, B., Ott, O. J., Rubner, Y., Multhoff, G., Sauer, R., Fietkau, R., and Gaipl, U. S. (2011). Radiation combined with hyperthermia induces HSP70-dependent maturation of dendritic cells and release of pro-inflammatory cytokines by dendritic cells and macrophages. Radiother. Oncol. 101, 109-115.
    • (2011) Radiother. Oncol. , vol.101 , pp. 109-115
    • Schildkopf, P.1    Frey, B.2    Ott, O.J.3    Rubner, Y.4    Multhoff, G.5    Sauer, R.6    Fietkau, R.7    Gaipl, U.S.8
  • 162
    • 84862667418 scopus 로고    scopus 로고
    • Basal HIF-1a expression levels are not predictive for radiosensitivity of human cancer cell lines
    • Schilling, D., Bayer, C., Emmerich, K., Molls, M., Vaupel, P., Huber, R. M., and Multhoff, G. (2012a). Basal HIF-1a expression levels are not predictive for radiosensitivity of human cancer cell lines. Strahlenther. Onkol. 188, 353-358.
    • (2012) Strahlenther. Onkol. , vol.188 , pp. 353-358
    • Schilling, D.1    Bayer, C.2    Emmerich, K.3    Molls, M.4    Vaupel, P.5    Huber, R.M.6    Multhoff, G.7
  • 163
    • 84863062001 scopus 로고    scopus 로고
    • Radiosensitization of normoxic and hypoxic H1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1a
    • doi:10.1371/journal.pone.0031110
    • Schilling, D., Bayer, C., Emmerich, K., Molls, M., Vaupel, P., Huber, R. M., and Multhoff, G. (2012b). Radiosensitization of normoxic and hypoxic H1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1a. PLoS ONE 7, e31110. doi:10.1371/journal.pone.0031110
    • (2012) PLoS ONE , vol.7
    • Schilling, D.1    Bayer, C.2    Emmerich, K.3    Molls, M.4    Vaupel, P.5    Huber, R.M.6    Multhoff, G.7
  • 164
    • 68849112162 scopus 로고    scopus 로고
    • Binding of heat shock protein 70 to extracellular phosphatidylserine promotes killing of normoxic and hypoxic tumor cells
    • Schilling, D., Gehrmann, M., Steinem, C., De Maio, A., Pockley, A. G., Abend, M., Molls, M., and Multhoff, G. (2009). Binding of heat shock protein 70 to extracellular phosphatidylserine promotes killing of normoxic and hypoxic tumor cells. FASEB J. 23, 2467-2477.
    • (2009) FASEB J. , vol.23 , pp. 2467-2477
    • Schilling, D.1    Gehrmann, M.2    Steinem, C.3    De Maio, A.4    Pockley, A.G.5    Abend, M.6    Molls, M.7    Multhoff, G.8
  • 165
    • 0035075597 scopus 로고    scopus 로고
    • Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing
    • Sebbagh, M., Renvoize, C., Hamelin, J., Riche, N., Bertoglio, J., and Breard, J. (2001). Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing. Nat. Cell Biol. 3, 346-352.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 346-352
    • Sebbagh, M.1    Renvoize, C.2    Hamelin, J.3    Riche, N.4    Bertoglio, J.5    Breard, J.6
  • 166
    • 35148828429 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 (HIF-1) pathway
    • cm8
    • Semenza, G. L. (2007). Hypoxia-inducible factor 1 (HIF-1) pathway. Sci. STKE 2007, cm8.
    • (2007) Sci. STKE , vol.2007
    • Semenza, G.L.1
  • 167
    • 33847646709 scopus 로고    scopus 로고
    • Ionizing radiation stimulates secretion of pro-inflammatory cytokines: dose-response relationship, mechanisms and implications
    • Shan, Y. X., Jin, S. Z., Liu, X. D., Liu, Y., and Liu, S. Z. (2007). Ionizing radiation stimulates secretion of pro-inflammatory cytokines: dose-response relationship, mechanisms and implications. Radiat. Environ. Biophys. 46, 21-29.
    • (2007) Radiat. Environ. Biophys. , vol.46 , pp. 21-29
    • Shan, Y.X.1    Jin, S.Z.2    Liu, X.D.3    Liu, Y.4    Liu, S.Z.5
  • 168
    • 0036208492 scopus 로고    scopus 로고
    • Formation of the androgen receptor transcription complex
    • Shang, Y., Myers, M., and Brown, M. (2002). Formation of the androgen receptor transcription complex. Mol. Cell 9, 601-610.
    • (2002) Mol. Cell , vol.9 , pp. 601-610
    • Shang, Y.1    Myers, M.2    Brown, M.3
  • 169
    • 34247573392 scopus 로고    scopus 로고
    • Cell-permeable hypoxia-inducible factor-1 (HIF-1) antagonists function as tumor radiosensitizers
    • Shi, M., Guo, X. T., Shu, M. G., Chen, F. L., and Li, L. W. (2007). Cell-permeable hypoxia-inducible factor-1 (HIF-1) antagonists function as tumor radiosensitizers. Med. Hypotheses 69, 33-35.
    • (2007) Med. Hypotheses , vol.69 , pp. 33-35
    • Shi, M.1    Guo, X.T.2    Shu, M.G.3    Chen, F.L.4    Li, L.W.5
  • 170
    • 34547660100 scopus 로고    scopus 로고
    • Preclinical evaluation of YC-1, a HIF inhibitor, for the prevention of tumor spreading
    • Shin, D. H., Kim, J. H., Jung, Y. J., Kim, K. E., Jeong, J. M., Chun, Y. S., and Park, J. W. (2007). Preclinical evaluation of YC-1, a HIF inhibitor, for the prevention of tumor spreading. Cancer Lett. 255, 107-116.
    • (2007) Cancer Lett. , vol.255 , pp. 107-116
    • Shin, D.H.1    Kim, J.H.2    Jung, Y.J.3    Kim, K.E.4    Jeong, J.M.5    Chun, Y.S.6    Park, J.W.7
  • 171
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-κB is suppressed by curcumin (diferuloylmethane) [corrected]
    • Singh, S., and Aggarwal, B. B. (1995). Activation of transcription factor NF-κB is suppressed by curcumin (diferuloylmethane) [corrected]. J. Biol. Chem. 270, 24995-25000.
    • (1995) J. Biol. Chem. , vol.270 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 172
    • 33744490370 scopus 로고    scopus 로고
    • Biological effects of curcumin and its role in cancer chemoprevention and therapy
    • Singh, S., and Khar, A. (2006). Biological effects of curcumin and its role in cancer chemoprevention and therapy. Anticancer Agents Med. Chem. 6, 259-270.
    • (2006) Anticancer Agents Med. Chem. , vol.6 , pp. 259-270
    • Singh, S.1    Khar, A.2
  • 173
    • 61449206288 scopus 로고    scopus 로고
    • Radiation-induced HIF-1a cell survival pathway is inhibited by soy isoflavones in prostate cancer cells
    • Singh-Gupta, V., Zhang, H., Banerjee, S., Kong, D., Raffoul, J. J., Sarkar, F. H., and Hillman, G. G. (2009). Radiation-induced HIF-1a cell survival pathway is inhibited by soy isoflavones in prostate cancer cells. Int. J. Cancer 124, 1675-1684.
    • (2009) Int. J. Cancer , vol.124 , pp. 1675-1684
    • Singh-Gupta, V.1    Zhang, H.2    Banerjee, S.3    Kong, D.4    Raffoul, J.J.5    Sarkar, F.H.6    Hillman, G.G.7
  • 175
    • 33750411459 scopus 로고    scopus 로고
    • Gamma-irradiation-induced intercellular adhesion molecule-1 (ICAM-1) expression is associated with catalase: activation of Ap-1 and JNK
    • Son, E. W., Rhee, D. K., and Pyo, S. (2006). Gamma-irradiation-induced intercellular adhesion molecule-1 (ICAM-1) expression is associated with catalase: activation of Ap-1 and JNK. J. Toxicol. Environ. Health Part A 69, 2137-2155.
    • (2006) J. Toxicol. Environ. Health Part A , vol.69 , pp. 2137-2155
    • Son, E.W.1    Rhee, D.K.2    Pyo, S.3
  • 176
    • 77955373319 scopus 로고    scopus 로고
    • Piceatannol, a catechol-type polyphenol, inhibits phorbol ester-induced NF-κB activation and cyclooxygenase-2 expression in human breast epithelial cells: cysteine 179 of IKKβ as a potential target
    • Son, P. S., Park, S. A., Na, H. K., Jue, D. M., Kim, S., and Surh, Y. J. (2010). Piceatannol, a catechol-type polyphenol, inhibits phorbol ester-induced NF-κB activation and cyclooxygenase-2 expression in human breast epithelial cells: cysteine 179 of IKKβ as a potential target. Carcinogenesis 31, 1442-1449.
    • (2010) Carcinogenesis , vol.31 , pp. 1442-1449
    • Son, P.S.1    Park, S.A.2    Na, H.K.3    Jue, D.M.4    Kim, S.5    Surh, Y.J.6
  • 177
    • 84855334252 scopus 로고    scopus 로고
    • Effect of HMGB1 silencing on cell proliferation, invasion and apoptosis of MGC-803 gastric cancer cells
    • Song, B., Song, W. G., Li, Z. J., Xu, Z. F., Wang, X. W., Wang, C. X., and Liu, J. (2012). Effect of HMGB1 silencing on cell proliferation, invasion and apoptosis of MGC-803 gastric cancer cells. Cell Biochem. Funct. 30, 11-17.
    • (2012) Cell Biochem. Funct. , vol.30 , pp. 11-17
    • Song, B.1    Song, W.G.2    Li, Z.J.3    Xu, Z.F.4    Wang, X.W.5    Wang, C.X.6    Liu, J.7
  • 178
    • 0031158934 scopus 로고    scopus 로고
    • Cancer immunology
    • Srivastava, P. K. (1997). Cancer immunology. Methods 12, 115-116.
    • (1997) Methods , vol.12 , pp. 115-116
    • Srivastava, P.K.1
  • 180
    • 0031005361 scopus 로고    scopus 로고
    • Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent
    • Stebbins, C. E., Russo, A. A., Schneider, C., Rosen, N., Hartl, F. U., and Pavletich, N. P. (1997). Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Cell 89, 239-250.
    • (1997) Cell , vol.89 , pp. 239-250
    • Stebbins, C.E.1    Russo, A.A.2    Schneider, C.3    Rosen, N.4    Hartl, F.U.5    Pavletich, N.P.6
  • 182
    • 0018080307 scopus 로고
    • Repopulation of gamma-irradiated Lewis lung carcinoma by malignant cells and host macrophage progenitors
    • Stephens, T. C., Currie, G. A., and Peacock, J. H. (1978). Repopulation of gamma-irradiated Lewis lung carcinoma by malignant cells and host macrophage progenitors. Br. J. Cancer 38, 573-582.
    • (1978) Br. J. Cancer , vol.38 , pp. 573-582
    • Stephens, T.C.1    Currie, G.A.2    Peacock, J.H.3
  • 183
    • 34748904141 scopus 로고    scopus 로고
    • The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN
    • Sun, Y., St. Clair, D. K., Fang, F., Warren, G. W., Rangnekar, V. M., Crooks, P. A., and St. Clair, W. H. (2007). The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN. Mol. Cancer Ther. 6, 2477-2486.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 2477-2486
    • Sun, Y.1    Clair, S.D.K.2    Fang, F.3    Warren, G.W.4    Rangnekar, V.M.5    Crooks, P.A.6    Clair, S.W.H.7
  • 184
    • 46749127067 scopus 로고    scopus 로고
    • Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-κB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-κBα kinase, leading to potentiation of apoptosis
    • Sung, B., Pandey, M. K., Ahn, K. S., Yi, T., Chaturvedi, M. M., Liu, M., and Aggarwal, B. B. (2008). Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-κB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-κBα kinase, leading to potentiation of apoptosis. Blood 111, 4880-4891.
    • (2008) Blood , vol.111 , pp. 4880-4891
    • Sung, B.1    Pandey, M.K.2    Ahn, K.S.3    Yi, T.4    Chaturvedi, M.M.5    Liu, M.6    Aggarwal, B.B.7
  • 185
    • 41649087170 scopus 로고    scopus 로고
    • Intrinsic radiation sensitivity: cellular signaling is the key
    • Szumiel, I. (2008). Intrinsic radiation sensitivity: cellular signaling is the key. Radiat. Res. 169, 249-258.
    • (2008) Radiat. Res. , vol.169 , pp. 249-258
    • Szumiel, I.1
  • 187
    • 0033634977 scopus 로고    scopus 로고
    • TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
    • Takaesu, G., Kishida, S., Hiyama, A., Yamaguchi, K., Shibuya, H., Irie, K., Ninomiya-Tsuji, J., and Matsumoto, K. (2000). TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol. Cell 5, 649-658.
    • (2000) Mol. Cell , vol.5 , pp. 649-658
    • Takaesu, G.1    Kishida, S.2    Hiyama, A.3    Yamaguchi, K.4    Shibuya, H.5    Irie, K.6    Ninomiya-Tsuji, J.7    Matsumoto, K.8
  • 188
    • 1642539107 scopus 로고    scopus 로고
    • Enhanced radiosensitization and chemosensitization in NF-κB-suppressed human oral cancer cells via the inhibition of γ-irradiation-and 5-FU-induced production of IL-6 and IL-8
    • Tamatani, T., Azuma, M., Ashida, Y., Motegi, K., Takashima, R., Harada, K., Kawaguchi, S., and Sato, M. (2004). Enhanced radiosensitization and chemosensitization in NF-κB-suppressed human oral cancer cells via the inhibition of γ-irradiation-and 5-FU-induced production of IL-6 and IL-8. Int. J. Cancer 108, 912-921.
    • (2004) Int. J. Cancer , vol.108 , pp. 912-921
    • Tamatani, T.1    Azuma, M.2    Ashida, Y.3    Motegi, K.4    Takashima, R.5    Harada, K.6    Kawaguchi, S.7    Sato, M.8
  • 189
    • 35848957914 scopus 로고    scopus 로고
    • Cepharanthin-enhanced radiosensitivity through the inhibition of radiation-induced nuclear factor-κB activity in human oral squamous cell carcinoma cells
    • Tamatani, T., Azuma, M., Motegi, K., Takamaru, N., Kawashima, Y., and Bando, T. (2007). Cepharanthin-enhanced radiosensitivity through the inhibition of radiation-induced nuclear factor-κB activity in human oral squamous cell carcinoma cells. Int. J. Oncol. 31, 761-768.
    • (2007) Int. J. Oncol. , vol.31 , pp. 761-768
    • Tamatani, T.1    Azuma, M.2    Motegi, K.3    Takamaru, N.4    Kawashima, Y.5    Bando, T.6
  • 190
    • 41849084513 scopus 로고    scopus 로고
    • A phase II study of mifepristone (RU-486) in castration-resistant prostate cancer, with a correlative assessment of androgen-related hormones
    • Taplin, M. E., Manola, J., Oh, W. K., Kantoff, P. W., Bubley, G. J., Smith, M., Barb, D., Mantzoros, C., Gelmann, E. P., and Balk, S. P. (2008). A phase II study of mifepristone (RU-486) in castration-resistant prostate cancer, with a correlative assessment of androgen-related hormones. BJU Int. 101, 1084-1089.
    • (2008) BJU Int. , vol.101 , pp. 1084-1089
    • Taplin, M.E.1    Manola, J.2    Oh, W.K.3    Kantoff, P.W.4    Bubley, G.J.5    Smith, M.6    Barb, D.7    Mantzoros, C.8    Gelmann, E.P.9    Balk, S.P.10
  • 192
    • 42749084082 scopus 로고    scopus 로고
    • The impact of p53 and p73 on aneuploidy and cancer
    • Tomasini, R., Mak, T. W., and Melino, G. (2008). The impact of p53 and p73 on aneuploidy and cancer. Trends Cell Biol. 18, 244-252.
    • (2008) Trends Cell Biol. , vol.18 , pp. 244-252
    • Tomasini, R.1    Mak, T.W.2    Melino, G.3
  • 193
    • 4344697308 scopus 로고    scopus 로고
    • Heat-shock protein 70 and heat-shock protein 90 associate with Toll-like receptor 4 in response to bacterial lipopolysaccharide
    • Triantafilou, M., and Triantafilou, K. (2004). Heat-shock protein 70 and heat-shock protein 90 associate with Toll-like receptor 4 in response to bacterial lipopolysaccharide. Biochem. Soc. Trans. 32, 636-639.
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 636-639
    • Triantafilou, M.1    Triantafilou, K.2
  • 194
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri, G. (2003). Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3, 133-146.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 195
    • 63849257538 scopus 로고    scopus 로고
    • Induction of autophagic cell death and radiosensitization by the pharmacological inhibition of nuclear factor-kappa B activation in human glioma cell lines
    • Tsuboi, Y., Kurimoto, M., Nagai, S., Hayakawa, Y., Kamiyama, H., Hayashi, N., Kitajima, I., and Endo, S. (2009). Induction of autophagic cell death and radiosensitization by the pharmacological inhibition of nuclear factor-kappa B activation in human glioma cell lines. J. Neurosurg. 110, 594-604.
    • (2009) J. Neurosurg. , vol.110 , pp. 594-604
    • Tsuboi, Y.1    Kurimoto, M.2    Nagai, S.3    Hayakawa, Y.4    Kamiyama, H.5    Hayashi, N.6    Kitajima, I.7    Endo, S.8
  • 196
    • 0036285034 scopus 로고    scopus 로고
    • c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability
    • Vafa, O., Wade, M., Kern, S., Beeche, M., Pandita, T. K., Hampton, G. M., and Wahl, G. M. (2002). c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol. Cell 9, 1031-1044.
    • (2002) Mol. Cell , vol.9 , pp. 1031-1044
    • Vafa, O.1    Wade, M.2    Kern, S.3    Beeche, M.4    Pandita, T.K.5    Hampton, G.M.6    Wahl, G.M.7
  • 198
    • 79958696614 scopus 로고    scopus 로고
    • Radiation-triggered tumor necrosis factor (TNF) a-NFκB cross-signaling favors survival advantage in human neuroblastoma cells
    • Veeraraghavan, J., Natarajan, M., Aravindan, S., Herman, T. S., and Aravindan, N. (2011a). Radiation-triggered tumor necrosis factor (TNF) a-NFκB cross-signaling favors survival advantage in human neuroblastoma cells. J. Biol. Chem. 286, 21588-21600.
    • (2011) J. Biol. Chem. , vol.286 , pp. 21588-21600
    • Veeraraghavan, J.1    Natarajan, M.2    Aravindan, S.3    Herman, T.S.4    Aravindan, N.5
  • 199
    • 80052965034 scopus 로고    scopus 로고
    • Impact of curcumin, raspberry extract, and neem leaf extract on rel protein-regulated cell death/radiosensitization in pancreatic cancer cells
    • Veeraraghavan, J., Natarajan, M., Lagisetty, P., Awasthi, V., Herman, T. S., and Aravindan, N. (2011b). Impact of curcumin, raspberry extract, and neem leaf extract on rel protein-regulated cell death/radiosensitization in pancreatic cancer cells. Pancreas 40, 1107-1119.
    • (2011) Pancreas , vol.40 , pp. 1107-1119
    • Veeraraghavan, J.1    Natarajan, M.2    Lagisetty, P.3    Awasthi, V.4    Herman, T.S.5    Aravindan, N.6
  • 200
    • 44849084963 scopus 로고    scopus 로고
    • Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages
    • Vega, V. L., Rodriguez-Silva, M., Frey, T., Gehrmann, M., Diaz, J. C., Steinem, C., Multhoff, G., Arispe, N., and De Maio, A. (2008). Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages. J. Immunol. 180, 4299-4307.
    • (2008) J. Immunol. , vol.180 , pp. 4299-4307
    • Vega, V.L.1    Rodriguez-Silva, M.2    Frey, T.3    Gehrmann, M.4    Diaz, J.C.5    Steinem, C.6    Multhoff, G.7    Arispe, N.8    De Maio, A.9
  • 201
    • 0029858387 scopus 로고    scopus 로고
    • TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB
    • Wang, C. Y., Mayo, M. W., and Baldwin, A. S. Jr. (1996). TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 274, 784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin Jr., A.S.3
  • 203
    • 77954219789 scopus 로고    scopus 로고
    • Inflammatory cytokines are associated with the development of symptom burden in patients with NSCLC undergoing concurrent chemoradiation therapy
    • Wang, X. S., Shi, Q., Williams, L. A., Mao, L., Cleeland, C. S., Komaki, R. R., Mobley, G. M., and Liao, Z. (2010). Inflammatory cytokines are associated with the development of symptom burden in patients with NSCLC undergoing concurrent chemoradiation therapy. Brain Behav. Immun. 24, 968-974.
    • (2010) Brain Behav. Immun. , vol.24 , pp. 968-974
    • Wang, X.S.1    Shi, Q.2    Williams, L.A.3    Mao, L.4    Cleeland, C.S.5    Komaki, R.R.6    Mobley, G.M.7    Liao, Z.8
  • 204
    • 66649102550 scopus 로고    scopus 로고
    • Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4
    • Wheeler, D. S., Chase, M. A., Senft, A. P., Poynter, S. E., Wong, H. R., and Page, K. (2009). Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4. Respir. Res. 10, 31.
    • (2009) Respir. Res. , vol.10 , pp. 31
    • Wheeler, D.S.1    Chase, M.A.2    Senft, A.P.3    Poynter, S.E.4    Wong, H.R.5    Page, K.6
  • 205
    • 84865149277 scopus 로고    scopus 로고
    • Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
    • doi:10.1007/s00109-011-0855-y. [Epub ahead of print].
    • Wong, C. C., Zhang, H., Gilkes, D. M., Chen, J., Wei, H., Chaturvedi, P., Hubbi, M. E., and Semenza, G. L. (2012). Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis. J. Mol. Med. doi:10.1007/s00109-011-0855-y. [Epub ahead of print].
    • (2012) J. Mol. Med.
    • Wong, C.C.1    Zhang, H.2    Gilkes, D.M.3    Chen, J.4    Wei, H.5    Chaturvedi, P.6    Hubbi, M.E.7    Semenza, G.L.8
  • 206
    • 31644432589 scopus 로고    scopus 로고
    • Regulatory T cells in immune surveillance and treatment of cancer
    • Yamaguchi, T., and Sakaguchi, S. (2006). Regulatory T cells in immune surveillance and treatment of cancer. Semin. Cancer Biol. 16, 115-123.
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 115-123
    • Yamaguchi, T.1    Sakaguchi, S.2
  • 207
    • 72449143164 scopus 로고    scopus 로고
    • Cigarette smoke extract induces COX-2 expression via a PKCa/c-Src/EGFR, PDGFR/PI3K/Akt/NF-κB pathway and p300 in tracheal smooth muscle cells
    • Yang, C. M., Lee, I. T., Lin, C. C., Yang, Y. L., Luo, S. F., Kou, Y. R., and Hsiao, L. D. (2009). Cigarette smoke extract induces COX-2 expression via a PKCa/c-Src/EGFR, PDGFR/PI3K/Akt/NF-κB pathway and p300 in tracheal smooth muscle cells. Am. J. Physiol. Lung Cell Mol. Physiol. 297, L892-L902.
    • (2009) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.297
    • Yang, C.M.1    Lee, I.T.2    Lin, C.C.3    Yang, Y.L.4    Luo, S.F.5    Kou, Y.R.6    Hsiao, L.D.7
  • 208
    • 33746507785 scopus 로고    scopus 로고
    • The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist-and antagonist-regulated transcription by androgen receptor
    • Yoon, H. G., and Wong, J. (2006). The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist-and antagonist-regulated transcription by androgen receptor. Mol. Endocrinol. 20, 1048-1060.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 1048-1060
    • Yoon, H.G.1    Wong, J.2
  • 209
    • 53149108942 scopus 로고    scopus 로고
    • Docosahexaenoic acid sensitizes Ramos cells to Gamma-irradiation-induced apoptosis through involvement of PPAR-γ activation and NF-κB suppression
    • Zand, H., Rahimipour, A., Salimi, S., and Shafiee, S. M. (2008). Docosahexaenoic acid sensitizes Ramos cells to Gamma-irradiation-induced apoptosis through involvement of PPAR-γ activation and NF-κB suppression. Mol. Cell. Biochem. 317, 113-120.
    • (2008) Mol. Cell. Biochem. , vol.317 , pp. 113-120
    • Zand, H.1    Rahimipour, A.2    Salimi, S.3    Shafiee, S.M.4
  • 210
    • 55449136468 scopus 로고    scopus 로고
    • TS-1 enhances the effect of radiotherapy by suppressing radiation-induced hypoxia-inducible factor-1 activation and inducing endothelial cell apoptosis
    • Zeng, L., Ou, G., Itasaka, S., Harada, H., Xie, X., Shibuya, K., Kizaka-Kondoh, S., Morinibu, A., Shinomiya, K., and Hiraoka, M. (2008). TS-1 enhances the effect of radiotherapy by suppressing radiation-induced hypoxia-inducible factor-1 activation and inducing endothelial cell apoptosis. Cancer Sci. 99, 2327-2335.
    • (2008) Cancer Sci. , vol.99 , pp. 2327-2335
    • Zeng, L.1    Ou, G.2    Itasaka, S.3    Harada, H.4    Xie, X.5    Shibuya, K.6    Kizaka-Kondoh, S.7    Morinibu, A.8    Shinomiya, K.9    Hiraoka, M.10
  • 211
    • 0028509456 scopus 로고
    • Ionizing radiation-induced IL-1 alpha, IL-6 and GM-CSF production by human lung cancer cells
    • Zhang, J. S., Nakatsugawa, S., Niwa, O., Ju, G. Z., and Liu, S. Z. (1994). Ionizing radiation-induced IL-1 alpha, IL-6 and GM-CSF production by human lung cancer cells. Chin. Med. J. 107, 653-657.
    • (1994) Chin. Med. J. , vol.107 , pp. 653-657
    • Zhang, J.S.1    Nakatsugawa, S.2    Niwa, O.3    Ju, G.Z.4    Liu, S.Z.5
  • 212
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics
    • Zhong, H., Chiles, K., Feldser, D., Laughner, E., Hanrahan, C., Georgescu, M. M., Simons, J. W., and Semenza, G. L. (2000). Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res. 60, 1541-1545.
    • (2000) Cancer Res. , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3    Laughner, E.4    Hanrahan, C.5    Georgescu, M.M.6    Simons, J.W.7    Semenza, G.L.8
  • 213
    • 0034743275 scopus 로고    scopus 로고
    • Effects of NF-κB1 (p50) targeted gene disruption on ionizing radiation-induced NF-κB activation and TNFα, IL-1α, IL-1β and IL-6 mRNA expression in vivo
    • Zhou, D., Yu, T., Chen, G., Brown, S. A., Yu, Z., Mattson, M. P., and Thompson, J. S. (2001). Effects of NF-κB1 (p50) targeted gene disruption on ionizing radiation-induced NF-κB activation and TNFα, IL-1α, IL-1β and IL-6 mRNA expression in vivo. Int. J. Radiat. Biol. 77, 763-772.
    • (2001) Int. J. Radiat. Biol. , vol.77 , pp. 763-772
    • Zhou, D.1    Yu, T.2    Chen, G.3    Brown, S.A.4    Yu, Z.5    Mattson, M.P.6    Thompson, J.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.