Mechanisms of interleukin-1β release

Immunobiology

Volumn 214, Issue 7, 2009, Pages 543-553

  Eder, Claudia ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Cytokine; Inflammasome; Interleukin 1; Leukocytes; Non classical release

Indexed keywords

CATHEPSIN D; CRYOPYRIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; TUBULIN; TUMOR NECROSIS FACTOR ALPHA; SIGNAL PEPTIDE;

AUTOIMMUNE DISEASE; BACTERIAL IMMUNITY; CELL MEMBRANE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOLYSIS; DENDRITIC CELL; EXOCYTOSIS; EXOSOME; HUMAN; INFLAMMATORY DISEASE; INNATE IMMUNITY; LYSOSOME; MACROPHAGE; MICROBIAL IMMUNITY; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; REVIEW; RNA TRANSCRIPTION; RNA TRANSLATION; ANIMAL; BIOSYNTHESIS; IMMUNOLOGY; SECRETION; SECRETORY PATHWAY;

ANIMALS; DENDRITIC CELLS; EXOSOMES; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-1BETA; LYSOSOMES; MACROPHAGES; PROTEIN SORTING SIGNALS; SECRETORY PATHWAY;

EID: 68649102975     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2008.11.007     Document Type: Review

References (83)

1. Allan S.M., Tyrrell P.J., and Rothwell N.J. Interleukin-1 and neuronal injury. Nat. Rev. Immunol. 5 (2005) 629-640
2. Amer A., Franchi L., Kanneganti T.D., Body-Malapel M., Ozören N., Brady G., Meshinchi S., Jagirdar R., Gewirtz A., Akira S., and Núñez G. Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf. J. Biol. Chem. 281 (2006) 35217-35223
3. Andrei C., Dazzi C., Lotti L., Torrisi M.R., Chimini G., and Rubartelli A. The secretory route of the leaderless protein interleukin 1β involves exocytosis of endolysosome-related vesicles. Mol. Biol. Cell 10 (1999) 1463-1475
4. 2 control lysosome-mediated IL-1β secretion: implications for inflammatory processes. Proc. Natl. Acad. Sci. USA 101 (2004) 9745-9750
5. Apte R.N., Dotan S., Elkabets M., White M.R., Reich E., Carmi Y., Song X., Dvozkin T., Krelin Y., and Voronov E. The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions. Cancer Metastasis Rev. 25 (2006) 387-408
6. Becq F., Hamon Y., Bajetto A., Gola M., Verrier B., and Chimini G. ABC1, an ATP-binding cassette transporter required for phagocytosis of apoptotic cells, generates a regulated anion flux after expression in Xenopus laevis oocytes. J. Biol. Chem. 272 (1997) 2695-2699
7. Bianco F., Pravettoni E., Colombo A., Schenk U., Möller T., Matteoli M., and Verderio C. Astrocyte-derived ATP induces vesicle shedding and IL-1β release from microglia. J. Immunol. 174 (2005) 7268-7277
8. Boyden E.D., and Dietrich W.F. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat. Genet. 38 (2006) 240-244
9. Brough D., and Rothwell N.J. Caspase-1-dependent processing of pro-interleukin-1β is cytosolic and precedes cell death. J. Cell Sci. 120 (2007) 772-781
10. Burger D., Dayer J.M., Palmer G., and Gabay C. Is IL-1 a good therapeutic target in the treatment of arthritis?. Best Pract. Res. Clin. Rheumatol. 20 (2006) 879-896
11. Carta S., Tassi S., Semino C., Fossati G., Mascagni P., Dinarello C.A., and Rubartelli A. Histone deacetylase inhibitors prevent exocytosis of interleukin-1β-containing secretory lysosomes: role of microtubules. Blood 108 (2006) 1618-1626
12. Chow A., Toomre D., Garrett W., and Mellman I. Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature 418 (2002) 988-994
13. Church L.D., Cook G.P., and McDermott M.F. Primer: inflammasomes and interleukin 1β in inflammatory disorders. Nat. Clin. Pract. Rheumatol. 4 (2008) 34-42
14. Cleves A.E., and Kelly R.B. Protein translocation: rehearsing the ABCs. Curr. Biol. 6 (1996) 276-278
15. Dinarello C.A. Biologic basis for interleukin-1 in disease. Blood 87 (1996) 2095-2147
16. Dinarello C.A. Blocking IL-1 in systemic inflammation. J. Exp. Med. 201 (2005) 1355-1359
17. Di Virgilio F. Liaisons dangereuses: P2X7 and the inflammasome. Trends Pharmacol. Sci. 28 (2007) 465-472
18. Di Virgilio F., Chiozzi P., Falzoni S., Ferrari D., Sanz J.M., Venketaraman V., and Baricordi O.R. Cytolytic P2X purinoceptors. Cell Death Differ. 5 (1998) 191-199
19. Dostert C., Pétrilli V., Van Bruggen R., Steele C., Mossman B.T., and Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320 (2008) 674-677
20. Edgeworth J.D., Spencer J., Phalipon A., Griffin G.E., and Sansonetti P.J. Cytotoxicity and interleukin-1β processing following Shigella flexneri infection of human monocyte-derived dendritic cells. Eur. J. Immunol. 32 (2002) 1464-1471
21. Eisenbarth S.C., Colegio O.R., O'Connor W., Sutterwala F.S., and Flavell R.A. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453 (2008) 1122-1126
22. Fink S.L., and Cookson B.T. Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell. Microbiol. 8 (2006) 1812-1825
23. Franchi L., Amer A., Body-Malapel M., Kanneganti T.D., Ozören N., Jagirdar R., Inohara N., Vandenabeele P., Bertin J., Coyle A., Grant E.P., and Núñez G. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin-1β in salmonella-infected macrophages. Nat. Immunol. 7 (2006) 576-582
24. Franchi L., Stoolman J., Kanneganti T.D., Verma A., Ramphal R., and Núñez G. Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation. Eur. J. Immunol. 37 (2007) 3030-3039
25. + for caspase-1 activation induced by intracellular and extracellular bacteria. J. Biol. Chem. 282 (2007) 18810-18818
26. Franchi L., Park J.H., Shaw M.H., Marina-Garcia N., Chen G., Kim Y.G., and Núñez G. Intracellular NOD-like receptors in innate immunity, infection and disease. Cell. Microbiol. 10 (2008) 1-8
27. Freche B., Reig N., and van der Goot F.G. The role of the inflammasome in cellular responses to toxins and bacterial effectors. Semin. Immunopathol. 29 (2007) 249-260
28. + T lymphocytes induce polarized exocytosis of secretory lysosomes by dendritic cells with release of interleukin-1β and cathepsin D. Blood 98 (2001) 2152-2159
29. Halban P.A., and Irminger J.C. Sorting and processing of secretory proteins. Biochem. J. 299 (1994) 1-18
30. Halle A., Hornung V., Petzold G.C., Stewart C.R., Monks B.G., Reinheckel T., Fitzgerald K.A., Latz E., Moore K.J., and Golenbock D.T. The NALP3 inflammasome is involved in the innate immune response to amyloid-β. Nat. Immunol. 9 (2008) 857-865
31. Hamon Y., Luciani M.F., Becq F., Verrier B., Rubartelli A., and Chimini G. Interleukin-1β secretion is impaired by inhibitors of the ATP binding cassette transporter, ABC1. Blood 90 (1997) 2911-2915
32. Hogquist K.A., Unanue E.R., and Chaplin D.D. Release of IL-1 from mononuclear phagocytes. J. Immunol. 147 (1991) 2181-2186
33. Holt O.J., Gallo F., and Griffiths G.M. Regulating secretory lysosomes. J. Biochem. 140 (2006) 7-12
34. Ikeda Y., Murakami A., Fujimura Y., Tachibana H., Yamada K., Masuda D., Hirano K., Yamashita S., and Ohigashi H. Aggregated ursolic acid, a natural triterpenoid, induces IL-1β release from murine peritoneal macrophages: role of CD36. J. Immunol. 178 (2007) 4854-4864
35. + release. Am. J. Physiol. 286 (2004) C1100-C1108
36. Kanneganti T.D., Body-Malapel M., Amer A., Park J.H., Whitfield J., Franchi L., Taraporewala Z.F., Miller D., Patton J.T., Inohara N., and Núñez G. Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J. Biol. Chem. 281 (2006) 36560-36568
37. Kanneganti T.D., Ozören N., Body-Malapel M., Amer A., Park J.H., Franchi L., Whitfield J., Barchet W., Colonna M., Vandenabeele P., Bertin J., Coyle A., Grant E.P., Akira S., and Núñez G. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 440 (2006) 233-236
38. Kanneganti T.D., Lamkanfi M., Kim Y.G., Chen G., Park J.H., Franchi L., Vandenabeele P., and Núñez G. Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity 26 (2007) 433-443
39. Laliberte R.E., Eggler J., and Gabel C.A. ATP treatment of human monocytes promotes caspase-1 maturation and externalization. J. Biol. Chem. 274 (1999) 36944-36951
40. Lamkanfi M., Kanneganti T.D., Franchi L., and Núñez G. Caspase-1 inflammasomes in infection and inflammation. J. Leukocyte Biol. 82 (2007) 220-225
41. Le Feuvre R.A., Brough D., Iwakura Y., Takeda K., and Rothwell N.J. Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production. J. Biol. Chem. 277 (2002) 3210-3218
42. Locovei S., Scemes E., Qiu F., Spray D.C., and Dahl G. Pannexin1 is part of the pore forming unit of the P2X7 receptor death complex. FEBS Lett. 581 (2007) 483-488
43. Lotze M.T., Zeh H.J., Rubartelli A., Sparvero L.J., Amoscato A.A., Washburn N.R., Devera M.E., Liang X., Tör M., and Billiar T. The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity. Immunol. Rev. 220 (2007) 60-81
44. Luzio J.P., Pryor P.R., and Bright N.A. Lysosomes: fusion and function. Nat. Rev. Mol. Cell Biol. 8 (2007) 622-632
45. MacKenzie A., Wilson H.L., Kiss-Toth E., Dower S.K., North R.A., and Surprenant A. Rapid secretion of interleukin-1β by microvesicle shedding. Immunity 15 (2001) 825-835
46. Mariathasan S., and Monack D.M. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat. Rev. Immunol. 7 (2007) 31-40
47. Mariathasan S., Newton K., Monack D.M., Vucic D., French D.M., Lee W.P., Roose-Girma M., Erickson S., and Dixit V.M. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430 (2004) 213-218
48. Mariathasan S., Weiss D.S., Newton K., McBride J., O'Rourke K., Roose-Girma M., Lee W.P., Weinrauch Y., Monack D.M., and Dixit V.M. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440 (2006) 228-232
49. Martinon F., and Tschopp J. Inflammatory caspases and inflammasomes: master switches of inflammation. Cell. Death Differ. 14 (2007) 10-22
50. Martinon F., Agostini L., Meylan E., and Tschopp J. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr. Biol. 14 (2004) 1929-1934
51. Martinon F., Pétrilli V., Mayor A., Tardivel A., and Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440 (2006) 237-241
52. Marty V., Médina C., Combe C., Parnet P., and Amédée T. ATP-binding cassette transporter ABC1 is required for the release of interleukin-1β by P2X7-stimulated and lipopolysaccharide-primed mouse Schwann cells. Glia 49 (2005) 511-519
53. Miao E.A., Alpuche-Aranda C.M., Dors M., Clark A.E., Bader M.W., Miller S.I., and Aderem A. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat. Immunol. 7 (2006) 569-575
54. Misumi Y., Misumi Y., Miki K., Takatsuki A., Tamura G., and Ikehara Y. Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes. J. Biol. Chem. 261 (1986) 11398-11403
55. Ozören N., Masumoto J., Franchi L., Kanneganti T.D., Body-Malapel M., Ertürk I., Jagirdar R., Zhu L., Inohara N., Bertin J., Coyle A., Grant E.P., and Núñez G. Distinct roles of TLR2 and the adaptor ASC in IL-1β/IL-18 secretion in response to Listeria monocytogenes. J. Immunol. 176 (2006) 4337-4342
56. Pelegrin P., and Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X7 receptor. EMBO J. 25 (2006) 5071-5082
57. Pelegrin P., and Surprenant A. Pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1β release through a dye uptake-independent pathway. J. Biol. Chem. 282 (2007) 2386-2394
58. Perregaux D., and Gabel C.A. Interleukin-1β maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J. Biol. Chem. 269 (1994) 15195-15203
59. Perregaux D.G., and Gabel C.A. Human monocyte stimulus-coupled IL-1β post-translational processing: modulation via monovalent cations. Am. J. Physiol. 275 (1998) C1538-C1547
60. Perregaux D.G., Bhavsar K., Contillo L., Shi J., and Gabel C.A. Antimicrobial peptides initiate IL-1β post-translational processing: a novel role beyond innate immunity. J. Immunol. 168 (2002) 3024-3032
61. Pétrilli V., Dostert C., Muruve D.A., and Tschopp J. The inflammasome: a danger sensing complex triggering innate immunity. Curr. Opinion Immunol. 19 (2007) 615-622
62. Pétrilli V., Papin S., Dostert C., Mayor A., Martinon F., and Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell. Death Differ. 14 (2007) 1583-1589
63. Pizzirani C., Ferrari D., Chiozzi P., Adinolfi E., Sandonà D., Savaglio E., and Di Virgilio F. Stimulation of P2 receptors causes release of IL-1β-loaded microvesicles from human dendritic cells. Blood 109 (2007) 3856-3864
64. Qu Y., Franchi L., Núñez G., and Dubyak G.R. Nonclassical IL-1β secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J. Immunol. 179 (2007) 1913-1925
65. Raposo G., Nijman H.W., Stoorvogel W., Liejendekker R., Harding C.V., Melief C.J., and Geuze H.J. B lymphocytes secrete antigen-presenting vesicles. J. Exp. Med. 183 (1996) 1161-1172
66. Ratajczak J., Wysoczynski M., Hayek F., Janowska-Wieczorek A., and Ratajczak M.Z. Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication. Leukemia 20 (2006) 1487-1495
67. Rubartelli A., Cozzolino F., Talio M., and Sitia R. A novel secretory pathway for interleukin-1β, a protein lacking a signal sequence. EMBO J. 9 (1990) 1503-1510
68. Simi A., Tsakiri N., Wang P., and Rothwell N.J. Interleukin-1 and inflammatory neurodegeneration. Biochem. Soc. Trans. 35 (2007) 1122-1126
69. Stock C., Schilling T., Schwab A., and Eder C. Lysophosphatidylcholine stimulates IL-1β release from microglia via a P2X7 receptor-independent mechanism. J. Immunol. 177 (2006) 8560-8568
70. Sutterwala F.S., Ogura Y., Szczepanik M., Lara-Tejero M., Lichtenberger G.S., Grant E.P., Bertin J., Coyle A.J., Galán J.E., Askenase P.W., and Flavell R.A. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 24 (2006) 317-327
71. Sutterwala F.S., Ogura Y., and Flavell R.A. The inflammasome in pathogen recognition and inflammation. J. Leukocyte Biol. 82 (2007) 259-264
72. Sutterwala F.S., Mijares L.A., Li L., Ogura Y., Kazmierczak B.I., and Flavell R.A. Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J. Exp. Med. 204 (2007) 3235-3245
73. Tartakoff A.M. Perturbation of vesicular traffic with the carboxylic ionophore monensin. Cell 32 (1983) 1026-1028
74. Théry C., Zitvogel L., and Amigorena S. Exosomes: composition, biogenesis and function. Nat. Rev. Immunol. 2 (2002) 569-579
75. Ting J.P., Lovering R.C., Alnemri E.S., Bertin J., Boss J.M., Davis B.K., Flavell R.A., Girardin S.E., Godzik A., Harton J.A., Hoffman H.M., Hugot J.P., Inohara N., Mackenzie A., Maltais L.J., Nunez G., Ogura Y., Otten L.A., Philpott D., Reed J.C., Reith W., Schreiber S., Steimle V., and Ward P.A. The NLR gene family: a standard nomenclature. Immunity 28 (2008) 285-287
76. van Niel G., Porto-Carreiro I., Simoes S., and Raposo G. Exosomes: a common pathway for a specialized function. J. Biochem. 140 (2006) 13-21
77. Verhoef P.A., Estacion M., Schilling W., and Dubyak G.R. P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1β release. J. Immunol. 170 (2003) 5728-5738
78. Verhoef P.A., Kertesy S.B., Estacion M., Schilling W.P., and Dubyak G.R. Maitotoxin induces biphasic interleukin-1β secretion and membrane blebbing in murine macrophages. Mol. Pharmacol. 66 (2004) 909-920
79. Verhoef P.A., Kertesy S.B., Lundberg K., Kahlenberg J.M., and Dubyak G.R. Inhibitory effects of chloride on the activation of caspase-1, IL-1β secretion, and cytolysis by the P2X7 receptor. J. Immunol. 175 (2005) 7623-7634
80. 2. J. Immunol. 164 (2000) 5120-5124
81. Watkins L.R., Hansen M.K., Nguyen K.T., Lee J.E., and Maier S.F. Dynamic regulation of the proinflammatory cytokine, interleukin-1β: molecular biology for non-molecular biologists. Life Sci. 65 (1999) 449-481
82. Wickliffe K.E., Leppla S.H., and Moayeri M. Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome. Cell. Microbiol. 10 (2008) 332-343
83. Zhou X., Engel T., Goepfert C., Erren M., Assmann G., and von Eckardstein A. The ATP-binding cassette transporter A1 contributes to the secretion of interleukin 1β from macrophages, but not from monocytes. Biochem. Biophys. Res. Commun. 291 (2002) 598-604