메뉴 건너뛰기




Volumn 255, Issue 1, 2007, Pages 107-116

Preclinical evaluation of YC-1, a HIF inhibitor, for the prevention of tumor spreading

Author keywords

HIF 1; Metastasis; Tumor invasion; YC 1

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; ANTINEOPLASTIC AGENT; BETA TUBULIN; GUANYLATE CYCLASE ACTIVATOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; SMALL INTERFERING RNA;

EID: 34547660100     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2007.03.026     Document Type: Article
Times cited : (78)

References (39)
  • 1
    • 0035925098 scopus 로고    scopus 로고
    • Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects
    • Hockel M., and Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J. Natl. Cancer Inst. 93 (2001) 266-276
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 266-276
    • Hockel, M.1    Vaupel, P.2
  • 2
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia-a key regulatory factor in tumour growth
    • Harris A.L. Hypoxia-a key regulatory factor in tumour growth. Nature Rev. Cancer 2 (2002) 38-47
    • (2002) Nature Rev. Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 3
    • 0142154635 scopus 로고    scopus 로고
    • Oxygen-dependent and -independent regulation of HIF-1alpha
    • Chun Y.S., Kim M.S., and Park J.W. Oxygen-dependent and -independent regulation of HIF-1alpha. J. Korean Med. Sci. 17 (2002) 581-588
    • (2002) J. Korean Med. Sci. , vol.17 , pp. 581-588
    • Chun, Y.S.1    Kim, M.S.2    Park, J.W.3
  • 4
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang G.L., and Semenza G.L. Purification and characterization of hypoxia-inducible factor 1. J. Biol. Chem. 270 (1995) 1230-1237
    • (1995) J. Biol. Chem. , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 9
    • 0034282518 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer
    • Birner P., Schindl M., Obermair A., Plank C., Breitenecker G., and Oberhuber G. Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res. 60 (2000) 4693-4696
    • (2000) Cancer Res. , vol.60 , pp. 4693-4696
    • Birner, P.1    Schindl, M.2    Obermair, A.3    Plank, C.4    Breitenecker, G.5    Oberhuber, G.6
  • 10
    • 0034213146 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression
    • Zagzag D., Zhong H., Scalzitti J.M., Laughner E., Simons J.W., and Semenza G.L. Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer 88 (2000) 2606-2618
    • (2000) Cancer , vol.88 , pp. 2606-2618
    • Zagzag, D.1    Zhong, H.2    Scalzitti, J.M.3    Laughner, E.4    Simons, J.W.5    Semenza, G.L.6
  • 11
    • 4143050461 scopus 로고    scopus 로고
    • New anticancer strategies targeting HIF-1
    • Yeo E.J., Chun Y.S., and Park J.W. New anticancer strategies targeting HIF-1. Biochem. Pharmacol. 68 (2004) 1061-1069
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 1061-1069
    • Yeo, E.J.1    Chun, Y.S.2    Park, J.W.3
  • 12
    • 0031890057 scopus 로고    scopus 로고
    • Mechanism of YC-1-induced activation of soluble guanylyl cyclase
    • Friebe A., and Koesling D. Mechanism of YC-1-induced activation of soluble guanylyl cyclase. Mol. Pharmacol. 53 (1998) 123-127
    • (1998) Mol. Pharmacol. , vol.53 , pp. 123-127
    • Friebe, A.1    Koesling, D.2
  • 13
    • 1842525176 scopus 로고    scopus 로고
    • Versatile pharmacological actions of YC-1: anti-platelet to anticancer
    • Chun Y.S., Yeo E.J., and Park J.W. Versatile pharmacological actions of YC-1: anti-platelet to anticancer. Cancer Lett. 207 (2004) 1-7
    • (2004) Cancer Lett. , vol.207 , pp. 1-7
    • Chun, Y.S.1    Yeo, E.J.2    Park, J.W.3
  • 14
    • 0035871942 scopus 로고    scopus 로고
    • Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells
    • Chun Y.S., Yeo E.J., Choi E., Teng C.M., Bae J.M., Kim M.S., and Park J.W. Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells. Biochem. Pharmacol. 61 (2001) 947-954
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 947-954
    • Chun, Y.S.1    Yeo, E.J.2    Choi, E.3    Teng, C.M.4    Bae, J.M.5    Kim, M.S.6    Park, J.W.7
  • 15
    • 33846990665 scopus 로고    scopus 로고
    • A domain responsible for HIF-1alpha degradation by YC-1, a novel anticancer agent
    • Kim H.L., Yeo E.J., Chun Y.S., and Park J.W. A domain responsible for HIF-1alpha degradation by YC-1, a novel anticancer agent. Int. J. Oncol. 29 (2006) 255-260
    • (2006) Int. J. Oncol. , vol.29 , pp. 255-260
    • Kim, H.L.1    Yeo, E.J.2    Chun, Y.S.3    Park, J.W.4
  • 17
    • 23244454418 scopus 로고    scopus 로고
    • New drugs target hypoxia response in tumors
    • Garber K. New drugs target hypoxia response in tumors. J. Natl. Cancer Inst. 97 (2005) 1112-1114
    • (2005) J. Natl. Cancer Inst. , vol.97 , pp. 1112-1114
    • Garber, K.1
  • 18
    • 0037279517 scopus 로고    scopus 로고
    • The hypoxic tumour microenvironment and metastatic progression
    • Subarsky P., and Hill R.P. The hypoxic tumour microenvironment and metastatic progression. Clin. Exp. Metastasis 20 (2003) 237-250
    • (2003) Clin. Exp. Metastasis , vol.20 , pp. 237-250
    • Subarsky, P.1    Hill, R.P.2
  • 20
    • 0035205085 scopus 로고    scopus 로고
    • A new HIF-1 alpha variant induced by zinc ion suppresses HIF-1-mediated hypoxic responses
    • Chun Y.S., Choi E., Yeo E.J., Lee J.H., Kim M.S., and Park J.W. A new HIF-1 alpha variant induced by zinc ion suppresses HIF-1-mediated hypoxic responses. J. Cell Sci. 114 (2001) 4051-4061
    • (2001) J. Cell Sci. , vol.114 , pp. 4051-4061
    • Chun, Y.S.1    Choi, E.2    Yeo, E.J.3    Lee, J.H.4    Kim, M.S.5    Park, J.W.6
  • 22
  • 23
    • 2342611976 scopus 로고    scopus 로고
    • Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules
    • Moeller B.J., Cao Y., Li C.Y., and Dewhirst M.W. Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules. Cancer Cell 5 (2004) 429-441
    • (2004) Cancer Cell , vol.5 , pp. 429-441
    • Moeller, B.J.1    Cao, Y.2    Li, C.Y.3    Dewhirst, M.W.4
  • 26
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza G.L. Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3 (2003) 721-732
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 29
    • 20644462985 scopus 로고    scopus 로고
    • Hypoxia-induced tumor angiogenic pathway in head and neck cancer: an in vivo study
    • Kyzas P.A., Stefanou D., Batistatou A., and Agnantis N.J. Hypoxia-induced tumor angiogenic pathway in head and neck cancer: an in vivo study. Cancer Lett. 225 (2005) 297-304
    • (2005) Cancer Lett. , vol.225 , pp. 297-304
    • Kyzas, P.A.1    Stefanou, D.2    Batistatou, A.3    Agnantis, N.J.4
  • 30
    • 0036569941 scopus 로고    scopus 로고
    • Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients
    • Beasley N.J., Leek R., Alam M., Turley H., Cox G.J., Gatter K., Millard P., Fuggle S., and Harris A.L. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res. 62 (2002) 2493-2497
    • (2002) Cancer Res. , vol.62 , pp. 2493-2497
    • Beasley, N.J.1    Leek, R.2    Alam, M.3    Turley, H.4    Cox, G.J.5    Gatter, K.6    Millard, P.7    Fuggle, S.8    Harris, A.L.9
  • 32
    • 34547691671 scopus 로고    scopus 로고
    • H.H. Chen, W.C. Su, P.W. Lin, H.R. Guo, W.Y. Lee, Hypoxia-inducible factor-1alpha correlates with MET and metastasis in node-negative breast cancer, Breast Cancer Res. Treat. (in press).
  • 35
    • 33846229266 scopus 로고    scopus 로고
    • Endothelins induce CCR7 expression by breast tumor cells via endothelin receptor A and hypoxia-inducible factor-1
    • Wilson J.L., Burchell J., and Grimshaw M.J. Endothelins induce CCR7 expression by breast tumor cells via endothelin receptor A and hypoxia-inducible factor-1. Cancer Res. 66 (2006) 11802-11807
    • (2006) Cancer Res. , vol.66 , pp. 11802-11807
    • Wilson, J.L.1    Burchell, J.2    Grimshaw, M.J.3
  • 36
    • 24644488689 scopus 로고    scopus 로고
    • Regulation of phosphoglucose isomerase/autocrine motility factor expression by hypoxia
    • Funasaka T., Yanagawa T., Hogan V., and Raz A. Regulation of phosphoglucose isomerase/autocrine motility factor expression by hypoxia. FASEB J. 19 (2005) 1422-1430
    • (2005) FASEB J. , vol.19 , pp. 1422-1430
    • Funasaka, T.1    Yanagawa, T.2    Hogan, V.3    Raz, A.4
  • 37
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: pathophysiology and therapeutics
    • Semenza G.L. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol. Med. 8 (2002) S62-S67
    • (2002) Trends Mol. Med. , vol.8
    • Semenza, G.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.