The androgen receptor recruits nuclear receptor corepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists

Journal of Biological Chemistry

Volumn 280, Issue 8, 2005, Pages 6511-6519

  Hodgson, Myles C ^a   Astapova, Inna ^a   Cheng, Shinta ^a   Lee, Larissa J ^a   Verhoeven, Manon C ^a   Choi, Eunis ^a   Balk, Steven P ^a   Hollenberg, Anthony N ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CONCENTRATION (PROCESS); IMMUNOLOGY; PRECIPITATION (CHEMICAL); TUMORS;

ANDROGEN RECEPTORS (AR); CHROMATINS; DIHYDROTESTOSTERONE (DHT); IMMUNOPRECIPITATION;

MOLECULAR BIOLOGY;

ANDROGEN RECEPTOR; ANDROSTANOLONE; BICALUTAMIDE; MIFEPRISTONE; NUCLEAR RECEPTOR COREPRESSOR; SMALL INTERFERING RNA; TAU PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIGAND BINDING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RECEPTOR BLOCKING; RECEPTOR UPREGULATION;

BINDING SITES; BINDING, COMPETITIVE; CELL LINE; CELL LINE, TUMOR; DIHYDROTESTOSTERONE; HORMONE ANTAGONISTS; HUMANS; MIFEPRISTONE; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECEPTORS, ANDROGEN; REPRESSOR PROTEINS; TRANSFECTION;

EID: 14844288915     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M408972200     Document Type: Article

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