IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis.

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Volumn 17, Issue 14, 2003, Pages 2115-2117

  Jung, Yun Jin ^a   Isaacs, Jennifer S ^a   Lee, Sunmin ^a   Trepel, Jane ^a   Neckers, Len ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; ISOENZYME; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN SYNTHASE; PTGS2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE; VASCULOTROPIN A; VHL PROTEIN, HUMAN; VON HIPPEL LINDAU PROTEIN;

ARTICLE; BIOSYNTHESIS; HUMAN; INFLAMMATION; METABOLISM; NEOPLASM; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL LINE, TUMOR; CYCLOOXYGENASE 2; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFLAMMATION; INTERLEUKIN-1; ISOENZYMES; MEMBRANE PROTEINS; NEOPLASMS; NF-KAPPA B; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 0347334750     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: None     Document Type: Article

References (0)