The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation

Journal of Biological Chemistry

Volumn 272, Issue 38, 1997, Pages 23843-23850

  Grenert, James P ^a   Sullivan, William P ^a   Fadden, Patrick ^c   Haystead, Timothy A J ^c   Clark, Jenny ^b   Mimnaugh, Edward ^b   Krutzsch, Henry ^b   Ochel, Hans Joachim ^b   Schulte, Theodor W ^b   Sausville, Edward ^b   Neckers, Leonard M ^b   Toft, David O ^a,d  

^a MAYO CLINIC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90;

AMINO TERMINAL SEQUENCE; ARTICLE; HUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; STRUCTURE ANALYSIS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; BENZOQUINONES; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN BINDING; PROTEIN CONFORMATION; QUINONES; SEQUENCE DELETION;

EID: 0030863995     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.38.23843     Document Type: Article

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