Crotepoxide chemosensitizes tumor cells through inhibition of expression of proliferation, invasion, and angiogenic proteins linked to proinflammatory pathway

Journal of Biological Chemistry

Volumn 285, Issue 35, 2010, Pages 26987-26997

  Prasad, Sahdeo ^a   Yadav, Vivek R ^a   Sundaram, Chitra ^a   Reuter, Simone ^a   Hema, Padmanabhan S ^b   Nair, Mangalam S ^b   Chaturvedi, Madan M ^a   Aggarwal, Bharat B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b REGIONAL RESEARCH LABORATORY CSIR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ANTI-APOPTOSIS; ANTI-INFLAMMATORY ACTIVITY; ANTI-TUMORS; APOPTOSIS; CELL TYPES; CELLULAR RESPONSE; CHEMOTHERAPEUTIC AGENTS; CIGARETTE SMOKES; CYCLIND1; CYTOKINES; DIEPOXIDE; EPITHELIAL CELLS; HUMAN CANCER CELLS; INDUCED APOPTOSIS; LIPOPOLYSACCHARIDES; MOLECULAR BASIS; NUCLEAR FACTORS; NUCLEAR TRANSLOCATIONS; PHORBOL 12 MYRISTATE 13 ACETATES; PROINFLAMMATORY; REGULATED GENES; REPORTER-GENE EXPRESSION; SIGNALING PATHWAYS; SURVIVIN; TUMOR CELLS; TUMOR NECROSIS FACTORS;

CELL DEATH; DRUG PRODUCTS; PATHOLOGY; PHOSPHORYLATION; TUMORS;

GENE EXPRESSION;

ANTINEOPLASTIC AGENT; BORTEZOMIB; CIGARETTE SMOKE; CISPLATIN; CROTEPOXIDE; CYCLIN D1; CYCLOOXYGENASE 2; FLUOROURACIL; GELATINASE B; GENE PRODUCT; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE; MYC PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN MCL 1; SURVIVIN; SYNAPTOTAGMIN I; THALIDOMIDE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BONE MARROW CELL; CHEMOSENSITIZATION; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; TUMOR CELL;

ANGIOGENESIS INDUCING AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; EPOXY COMPOUNDS; HUMANS; INFLAMMATION MEDIATORS; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEOPLASMS; ZINGIBERACEAE;

KAEMPFERIA PULCHRA; ZINGIBER OFFICINALE;

EID: 77956246885     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.121061     Document Type: Article

References (55)

1. Kupchan, S. M., Hemingway, R. J., Coggon, P., McPhail, A. T., and Sim, G. A. (1968) J. Am. Chem. Soc. 90, 2982-2983
2. Kupchan, S. M., Hemingway, R. J., and Smith, R. M. (1969) J. Org. Chem. 34, 3898-3902
3. Stevenson, P. C., Veitch, N. C., and Simmonds, M. S. (2007) Phytochemistry 68, 1579-1586
4. Partha, P., and Hussain, A. B. M. E. (2007) Bangladesh Journal Plant Taxonomy 14, 129-145
5. Lotulung, P. D., Minarti, Kardono, L. B., and Kawanishi, K. (2008) Pak. J Biol. Sci. 11, 2447-2450
6. Lin, L. C., Shen, C. C., Shen, Y. C., and Tsai, T. H. (2006) J. Nat. Prod. 69, 842-844
7. Han, G. Q., Wei, L. H., Li, C. L., Qiao, L., Jia, Y. Z., and Zheng, Q. T. (1989) Acta Pharmacol. Sin. 24, 438-443
8. Taneja, S. C., Koul, S. K., Pushpangadan, P., Dhar, K. L., Daniewski, W. M., and Schilf, W. (1991) Phytochemistry 30, 871-874
9. Mulholland, D., Naidoo, N., Hutchings, A., Lavaud, C., and Massiot, G. (2000) Biochem. Syst. Ecol. 28, 595-597
10. Joseph, C. C., Magadula, J. J., and Nkunya, M. H. (2007) Nat. Prod. Res. 21, 1009-1015
11. Pancharoen, O., Tuntiwachwuttikul, P., and Taylor, W. C. (1989) Phytochemistry 28, 1143-1148
12. Pai, B. R., Rao, N. N., and Wariyar, N. S. (1970) Indian J. Chem. 8, 468
13. Demuth, M. R., Garrett, P. E., and White, J. D. (1976) J. Am. Chem. Soc. 98, 634-635
14. Bharti, A. C., and Aggarwal, B. B. (2002) Biochem. Pharmacol. 64, 883-888
15. Shishodia, S., and Aggarwal, B. B. (2004) J. Biol. Chem. 279, 47148-47158
16. Bharti, A. C., Shishodia, S., Reuben, J. M., Weber, D., Alexanian, R., Raj-Vadhan, S., Estrov, Z., Talpaz, M., and Aggarwal, B. B. (2004) Blood 103, 3175-3184
17. Sovak, M. A., Bellas, R. E., Kim, D. W., Zanieski, G. J., Rogers, A. E., Traish, A. M., and Sonenshein, G. E. (1997) J. Clin. Invest. 100, 2952-2960
18. Zerbini, L. F., Wang, Y., Cho, J. Y., and Libermann, T. A. (2003) Cancer Res. 63, 2206-2215
19. Prasad, S., Ravindran, J., and Aggarwal, B. B. (2010) Mol. Cell. Biochem. 336, 25-37
20. Pancharoen, O., Tuntiwachwuttikul, P., and Taylor, W. C. (1996) Phytochemistry 43, 305-308
21. Chaturvedi, M. M., LaPushin, R., and Aggarwal, B. B. (1994) J. Biol. Chem. 269, 14575-14583
22. Takada, Y., and Aggarwal, B. B. (2003) J. Biol. Chem. 278, 23390-23397
23. Takada, Y., Mukhopadhyay, A., Kundu, G. C., Mahabeleshwar, G. H., Singh, S., and Aggarwal, B. B. (2003) J. Biol. Chem. 278, 24233-24241
24. Pandey, M. K., Sandur, S. K., Sung, B., Sethi, G., Kunnumakkara, A. B., and Aggarwal, B. B. (2007) J. Biol. Chem. 282, 17340-17350
25. Sung, B., Pandey, M. K., and Aggarwal, B. B. (2007) Mol. Pharmacol. 71, 1703-1714
26. Darnay, B. G., Ni, J., Moore, P. A., and Aggarwal, B. B. (1999) J. Biol. Chem. 274, 7724-7731
27. Duyao, M. P., Kessler, D. J., Spicer, D. B., Bartholomew, C., Cleveland, J. L., Siekevitz, M., and Sonenshein, G. E. (1992) J. Biol. Chem. 267, 16288-16291
28. Guttridge, D. C., Albanese, C., Reuther, J. Y., Pestell, R. G., and Baldwin, A. S., Jr. (1999) Mol. Cell. Biol. 19, 5785-5799
29. You, M., Ku, P. T., Hrdlicková, R., and Bose, H. R., Jr. (1997) Mol. Cell. Biol. 17, 7328-7341
30. Catz, S. D., and Johnson, J. L. (2001) Oncogene 20, 7342-7351
31. Tamatani, M., Che, Y. H., Matsuzaki, H., Ogawa, S., Okado, H., Miyake, S., Mizuno, T., and Tohyama, M. (1999) J. Biol. Chem. 274, 8531-8538
32. Schwenzer, R., Siemienski, K., Liptay, S., Schubert, G., Peters, N., Scheurich, P., Schmid, R. M., and Wajant, H. (1999) J. Biol. Chem. 274, 19368-19374
33. van de Stolpe, A., Caldenhoven, E., Stade, B. G., Koenderman, L., Raaijmakers, J. A., Johnson, J. P., and van der Saag, P. T. (1994) J. Biol. Chem. 269, 6185-6192
34. Chilov, D., Kukk, E., Taira, S., Jeltsch, M., Kaukonen, J., Palotie, A., Joukov, V., and Alitalo, K. (1997) J. Biol. Chem. 272, 25176-25183
35. Estève, P. O., Chicoine, E., Robledo, O., Aoudjit, F., Descoteaux, A., Potworowski, E. F., and St-Pierre, Y. (2002) J. Biol. Chem. 277, 35150-35155
36. Mahon, T. M., and O'Neill, L. A. (1995) J. Biol. Chem. 270, 28557-28564
37. Natarajan, K., Singh, S., Burke, T. R., Jr., Grunberger, D., and Aggarwal, B. B. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 9090-9095
38. Finco, T. S., Beg, A. A., and Baldwin, A. S., Jr. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 11884-11888
39. Sandur, S. K., Ichikawa, H., Sethi, G., Ahn, K. S., and Aggarwal, B. B. (2006) J. Biol. Chem. 281, 17023-17033
40. Anto, R. J., Mukhopadhyay, A., Shishodia, S., Gairola, C. G., and Aggarwal, B. B. (2002) Carcinogenesis 23, 1511-1518
41. Nelsen, B., Hellman, L., and Sen, R. (1988) Mol. Cell. Biol. 8, 3526-3531
42. Sen, R., and Baltimore, D. (1986) Cell 47, 921-928
43. Thévenin, C., Kim, S. J., Rieckmann, P., Fujiki, H., Norcross, M. A., Sporn, M. B., Fauci, A. S., and Kehrl, J. H. (1990) New Biol 2, 793-800
44. Schreck, R., Rieber, P., and Baeuerle, P. A. (1991) EMBO J. 10, 2247-2258
45. Sizemore, N., Lerner, N., Dombrowski, N., Sakurai, H., and Stark, G. R. (2002) J. Biol. Chem. 277, 3863-3869
46. Yore, M. M., Liby, K. T., Honda, T., Gribble, G. W., and Sporn, M. B. (2006) Mol. Cancer Ther. 5, 3232-3239
47. Blonska, M., Shambharkar, P. B., Kobayashi, M., Zhang, D., Sakurai, H., Su, B., and Lin, X. (2005) J. Biol. Chem. 280, 43056-43063
48. Simeonidis, S., Stauber, D., Chen, G., Hendrickson, W. A., and Thanos, D. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 49-54
49. Hsu, H., Shu, H. B., Pan, M. G., and Goeddel, D. V. (1996) Cell 84, 299-308
50. Karin, M., and Ben-Neriah, Y. (2000) Annu. Rev. Immunol. 18, 621-663
51. Politi, C., Del Turco, D., Sie, J. M., Golinski, P. A., Tegeder, I., Deller, T., and Schultz, C. (2008) Neuropathol. Appl. Neurobiol. 34, 357-365
52. Sakurai, H., Miyoshi, H., Toriumi, W., and Sugita, T. (1999) J. Biol. Chem. 274, 10641-10648
53. Bhoj, V. G., and Chen, Z. J. (2009) Nature 458, 430-437
54. Shishodia, S., and Aggarwal, B. B. (2004) Cancer Treat. Res. 119, 139-173
55. Aggarwal, B. B., Kunnumakkara, A. B., Harikumar, K. B., Gupta, S. R., Tharakan, S. T., Koca, C., Dey, S., and Sung, B. (2009) Ann. N. Y. Acad. Sci. 1171, 59-76