메뉴 건너뛰기




Volumn 3, Issue 4, 2001, Pages 346-352

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CASPASE 3; GUANOSINE TRIPHOSPHATASE; MYOSIN LIGHT CHAIN; PROTEIN SERINE THREONINE KINASE; RHO FACTOR;

EID: 0035075597     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35070019     Document Type: Article
Times cited : (747)

References (43)
  • 2
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • (published erratum Nature 393, 396).
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1
  • 3
    • 0030916417 scopus 로고    scopus 로고
    • DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
    • (1997) Cell , vol.89 , pp. 175-184
    • Liu, X.1    Zou, H.2    Slaughter, C.3    Wang, X.4
  • 4
    • 0030918572 scopus 로고    scopus 로고
    • Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
    • (1997) Science , vol.276 , pp. 1571-1574
    • Rudel, T.1    Bokoch, G.M.2
  • 5
    • 0031443641 scopus 로고    scopus 로고
    • Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 13642-13647
    • Lee, N.1
  • 9
  • 13
    • 0032583203 scopus 로고    scopus 로고
    • SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis
    • (1998) J. Cell. Biol. , vol.143 , pp. 1361-1373
    • Huot, J.1
  • 17
    • 0029786313 scopus 로고    scopus 로고
    • Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
    • (1996) J. Biol. Chem. , vol.271 , pp. 20246-20249
    • Amano, M.1
  • 18
    • 9444242736 scopus 로고    scopus 로고
    • Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
    • (1996) Science , vol.273 , pp. 245-248
    • Kimura, K.1
  • 19
    • 0033615977 scopus 로고    scopus 로고
    • Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo
    • (1999) J. Cell. Biol. , vol.147 , pp. 1023-1038
    • Kawano, Y.1
  • 20
    • 9244220646 scopus 로고    scopus 로고
    • The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase
    • (1996) EMBO J. , vol.15 , pp. 1885-1893
    • Ishizaki, T.1
  • 25
    • 0030615004 scopus 로고    scopus 로고
    • p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions
    • (1997) FEBS Lett. , vol.404 , pp. 118-124
    • Ishizaki, T.1
  • 26
    • 0030656619 scopus 로고    scopus 로고
    • Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
    • (1997) Nature , vol.389 , pp. 990-994
    • Uehata, M.1
  • 27
    • 0032935495 scopus 로고    scopus 로고
    • An essential part for Rho-associated kinase in the transcellular invasion of tumor cells
    • (1999) Nature Med. , vol.5 , pp. 221-225
    • Itoh, K.1
  • 30
    • 0034017744 scopus 로고    scopus 로고
    • Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases
    • (2000) Mol. Pharmacol. , vol.57 , pp. 976-983
    • Ishizaki, T.1
  • 32
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 33
    • 0031759170 scopus 로고    scopus 로고
    • Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration
    • (1998) Nature Med. , vol.4 , pp. 1449-1452
    • Nagahara, H.1
  • 34
    • 14444288533 scopus 로고    scopus 로고
    • Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells
    • (1998) J. Cell. Biol. , vol.141 , pp. 1625-1636
    • Hirose, M.1
  • 35
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 37
    • 0032582343 scopus 로고    scopus 로고
    • Constitutively active α12, Gα13, and Gαq induce Rho-dependent neurite retraction through different signaling pathways
    • (1998) J. Biol. Chem. , vol.273 , pp. 28700-28707
    • Katoh, H.1
  • 38
    • 0008727013 scopus 로고    scopus 로고
    • Alterations of the actin polymerization status as an apoptotic morphological effector in HL-60 cells
    • (1999) J. Cell Biochem. , vol.75 , pp. 686-697
    • Rao, J.Y.1
  • 39
    • 0034602959 scopus 로고    scopus 로고
    • Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop
    • (2000) J. Biol. Chem. , vol.275 , pp. 3577-35782
    • Ohashi, K.1
  • 42
    • 0024449589 scopus 로고
    • The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells
    • (1989) EMBO J. , vol.8 , pp. 1087-1092
    • Chardin, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.