Crystal structure of an Hsp90-geldanamycin complex: Targeting of a protein chaperone by an antitumor agent

Cell

Volumn 89, Issue 2, 1997, Pages 239-250

  Stebbins, Charles E ^a   Russo, Alicia A ^b   Schneider, Christine ^c   Rosen, Neal ^b   Hartl, F Ulrich ^c   Pavletich, Nikola P ^b  

^a Weill Cornell Medical Center   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHAPERONE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

EUKARYOTA;

EID: 0031005361     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80203-2     Document Type: Article

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