-
1
-
-
70350780570
-
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-b pathways
-
Alarcon C., Zaromytidou AI, Xi Q, Gao S, Yu J, Fujisawa S, Barlas A, Miller AN, Manova-Todorova K, Macias MJ, et al. 2009. Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-b pathways. Cell 139: 757-769.
-
(2009)
Cell
, vol.139
, pp. 757-769
-
-
Alarcon, C.1
Zaromytidou, A.I.2
Xi, Q.3
Gao, S.4
Yu, J.5
Fujisawa, S.6
Barlas, A.7
Miller, A.N.8
Manova-Todorova, K.9
McIas, M.J.10
-
2
-
-
84886943235
-
Role of TAZ as mediator of Wnt signaling
-
Azzolin L., Zanconato F, Bresolin S, Forcato M, Basso G, Bicciato S, Cordenonsi M, Piccolo S. 2012. Role of TAZ as mediator of Wnt signaling. Cell 151: 1443-1456.
-
(2012)
Cell
, vol.151
, pp. 1443-1456
-
-
Azzolin, L.1
Zanconato, F.2
Bresolin, S.3
Forcato, M.4
Basso, G.5
Bicciato, S.6
Cordenonsi, M.7
Piccolo, S.8
-
3
-
-
0035007140
-
Topical application of the phospholipid growth factor lysophosphatidic acid promotes wound healing in vivo
-
Balazs L., Okolicany J, Ferrebee M, Tolley B, Tigyi G. 2001. Topical application of the phospholipid growth factor lysophosphatidic acid promotes wound healing in vivo. Am J Physiol Regul Integr Comp Physiol 280: R466-R472.
-
(2001)
Am J Physiol Regul Integr Comp Physiol
, vol.280
-
-
Balazs, L.1
Okolicany, J.2
Ferrebee, M.3
Tolley, B.4
Tigyi, G.5
-
4
-
-
79961063553
-
A cellbased assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription
-
Bao Y., Nakagawa K, Yang Z, Ikeda M, Withanage K, Ishigami-Yuasa M., Okuno Y, Hata S, Nishina H, Hata Y. 2011. A cellbased assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription. J Biochem 150: 199-208.
-
(2011)
J Biochem
, vol.150
, pp. 199-208
-
-
Bao, Y.1
Nakagawa, K.2
Yang, Z.3
Ikeda, M.4
Withanage, K.5
Ishigami-Yuasa, M.6
Okuno, Y.7
Hata, S.8
Nishina, H.9
Hata, Y.10
-
5
-
-
79955508089
-
Dynamics of adherens junctions in epithelial establishment, maintenance, and remodeling
-
Baum B., Georgiou M. 2011. Dynamics of adherens junctions in epithelial establishment, maintenance, and remodeling. J Cell Biol 192: 907-917.
-
(2011)
J Cell Biol
, vol.192
, pp. 907-917
-
-
Baum, B.1
Georgiou, M.2
-
6
-
-
76249125346
-
The WW domain protein Kibra acts upstream of Hippo in Drosophila
-
Baumgartner R., Poernbacher I, Buser N, Hafen E, Stocker H. 2010. The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev Cell 18: 309-316.
-
(2010)
Dev Cell
, vol.18
, pp. 309-316
-
-
Baumgartner, R.1
Poernbacher, I.2
Buser, N.3
Hafen, E.4
Stocker, H.5
-
7
-
-
77955868800
-
Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver
-
Benhamouche S., Curto M, Saotome I, Gladden AB, Liu CH, Giovannini M., McClatchey AI. 2010. Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver. Genes Dev 24: 1718-1730.
-
(2010)
Genes Dev
, vol.24
, pp. 1718-1730
-
-
Benhamouche, S.1
Curto, M.2
Saotome, I.3
Gladden, A.B.4
Liu, C.H.5
Giovannini, M.6
McClatchey, A.I.7
-
8
-
-
33750611115
-
Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway
-
Bennett FC., Harvey KF. 2006. Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway. Curr Biol 16: 2101-2110.
-
(2006)
Curr Biol
, vol.16
, pp. 2101-2110
-
-
Bennett, F.C.1
Harvey, K.F.2
-
9
-
-
0027291288
-
Expanded: A gene involved in the control of cell proliferation in imaginal discs
-
Boedigheimer M., Laughon A. 1993. Expanded: A gene involved in the control of cell proliferation in imaginal discs. Development 118: 1291-1301.
-
(1993)
Development
, vol.118
, pp. 1291-1301
-
-
Boedigheimer, M.1
Laughon, A.2
-
10
-
-
0030972542
-
Expanded functions in the apical cell domain to regulate the growth rate of imaginal discs
-
Boedigheimer MJ., Nguyen KP, Bryant PJ. 1997. Expanded functions in the apical cell domain to regulate the growth rate of imaginal discs. Dev Genet 20: 103-110.
-
(1997)
Dev Genet
, vol.20
, pp. 103-110
-
-
Boedigheimer, M.J.1
Nguyen, K.P.2
Bryant, P.J.3
-
11
-
-
80755136770
-
Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway
-
Boggiano JC., Vanderzalm PJ, Fehon RG. 2011. Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway. Dev Cell 21: 888-895.
-
(2011)
Dev Cell
, vol.21
, pp. 888-895
-
-
Boggiano, J.C.1
Vanderzalm, P.J.2
Fehon, R.G.3
-
13
-
-
78049451932
-
The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program
-
Cai J., Zhang N, Zheng Y, de Wilde RF, Maitra A, Pan D. 2010. The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. Genes Dev 24: 2383-2388.
-
(2010)
Genes Dev
, vol.24
, pp. 2383-2388
-
-
Cai, J.1
Zhang, N.2
Zheng, Y.3
de Wilde, R.F.4
Maitra, A.5
Pan, D.6
-
14
-
-
33748308721
-
Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation
-
Callus BA., Verhagen AM, Vaux DL. 2006. Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation. FEBS J 273: 4264-4276.
-
(2006)
FEBS J
, vol.273
, pp. 4264-4276
-
-
Callus, B.A.1
Verhagen, A.M.2
Vaux, D.L.3
-
15
-
-
36549074631
-
YAP1 increases organ size and expands undifferentiated progenitor cells
-
Camargo FD., Gokhale S, Johnnidis JB, Fu D, Bell GW, Jaenisch R, Brummelkamp TR. 2007. YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol 17: 2054-2060.
-
(2007)
Curr Biol
, vol.17
, pp. 2054-2060
-
-
Camargo, F.D.1
Gokhale, S.2
Johnnidis, J.B.3
Fu, D.4
Bell, G.W.5
Jaenisch, R.6
Brummelkamp, T.R.7
-
16
-
-
57749122174
-
YAP regulates neural progenitor cell number via the TEA domain transcription factor
-
Cao X., Pfaff SL, Gage FH. 2008. YAP regulates neural progenitor cell number via the TEA domain transcription factor. Genes Dev 22: 3320-3334.
-
(2008)
Genes Dev
, vol.22
, pp. 3320-3334
-
-
Cao, X.1
Pfaff, S.L.2
Gage, F.H.3
-
17
-
-
16444373346
-
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
-
Chan EH., Nousiainen M, Chalamalasetty RB, Schafer A, Nigg EA, Sillje HH. 2005. The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene 24: 2076-2086.
-
(2005)
Oncogene
, vol.24
, pp. 2076-2086
-
-
Chan, E.H.1
Nousiainen, M.2
Chalamalasetty, R.B.3
Schafer, A.4
Nigg, E.A.5
Sillje, H.H.6
-
18
-
-
42349088170
-
A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells
-
Chan SW., Lim CJ, Guo K, Ng CP, Lee I, Hunziker W, Zeng Q, Hong W. 2008. A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. Cancer Res 68: 2592-2598.
-
(2008)
Cancer Res
, vol.68
, pp. 2592-2598
-
-
Chan, S.W.1
Lim, C.J.2
Guo, K.3
Ng, C.P.4
Lee, I.5
Hunziker, W.6
Zeng, Q.7
Hong, W.8
-
19
-
-
79953223677
-
Hippo pathway-independent restriction of TAZ and YAP by angiomotin
-
Chan SW., Lim CJ, Chong YF, Pobbati AV, Huang C, Hong W. 2011. Hippo pathway-independent restriction of TAZ and YAP by angiomotin. J Biol Chem 286: 7018-7026.
-
(2011)
J Biol Chem
, vol.286
, pp. 7018-7026
-
-
Chan, S.W.1
Lim, C.J.2
Chong, Y.F.3
Pobbati, A.V.4
Huang, C.5
Hong, W.6
-
20
-
-
77957676987
-
The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila
-
Chen CL., Gajewski KM, Hamaratoglu F, Bossuyt W, Sansores-Garcia L., Tao C, Halder G. 2010. The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila. Proc Natl Acad Sci 107: 15810-15815.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 15810-15815
-
-
Chen, C.L.1
Gajewski, K.M.2
Hamaratoglu, F.3
Bossuyt, W.4
Sansores-Garcia, L.5
Tao, C.6
Halder, G.7
-
21
-
-
76149134716
-
Structural basis of YAP recognition by TEAD4 in the hippo pathway
-
Chen L., Chan SW, Zhang X, Walsh M, Lim CJ, Hong W, Song H. 2010. Structural basis of YAP recognition by TEAD4 in the hippo pathway. Genes Dev 24: 290-300.
-
(2010)
Genes Dev
, vol.24
, pp. 290-300
-
-
Chen, L.1
Chan, S.W.2
Zhang, X.3
Walsh, M.4
Lim, C.J.5
Hong, W.6
Song, H.7
-
22
-
-
84870261155
-
LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker
-
Chen D., Sun Y, Wei Y, Zhang P, Rezaeian AH, Teruya-Feldstein J, Gupta S, Liang H, Lin HK, Hung MC, et al. 2012. LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker. Nat Med 18: 1511-1517.
-
(2012)
Nat Med
, vol.18
, pp. 1511-1517
-
-
Chen, D.1
Sun, Y.2
Wei, Y.3
Zhang, P.4
Rezaeian, A.H.5
Teruya-Feldstein, J.6
Gupta, S.7
Liang, H.8
Lin, H.K.9
Hung, M.C.10
-
23
-
-
6944253410
-
Action of fat, four-jointed, dachsous and dachs in distal-to-proximal wing signaling
-
Cho E., Irvine KD. 2004. Action of fat, four-jointed, dachsous and dachs in distal-to-proximal wing signaling. Development 131: 4489-4500.
-
(2004)
Development
, vol.131
, pp. 4489-4500
-
-
Cho, E.1
Irvine, K.D.2
-
24
-
-
33749125438
-
Delineation of a Fat tumor suppressor pathway
-
Cho E., Feng Y, Rauskolb C, Maitra S, Fehon R, Irvine KD. 2006. Delineation of a Fat tumor suppressor pathway. Nat Genet 38: 1142-1150.
-
(2006)
Nat Genet
, vol.38
, pp. 1142-1150
-
-
Cho, E.1
Feng, Y.2
Rauskolb, C.3
Maitra, S.4
Fehon, R.5
Irvine, K.D.6
-
26
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cellrelated traits on breast cancer cells
-
Cordenonsi M., Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C., Inui M, Montagner M, Parenti AR, Poletti A, et al. 2011. The Hippo transducer TAZ confers cancer stem cellrelated traits on breast cancer cells. Cell 147: 759-772.
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
Forcato, M.4
Rosato, A.5
Frasson, C.6
Inui, M.7
Montagner, M.8
Parenti, A.R.9
Poletti, A.10
-
27
-
-
77950474987
-
Ajuba LIM proteins are negative regulators of the Hippo signaling pathway
-
Das Thakur M, Feng Y, Jagannathan R, Seppa MJ, Skeath JB, Longmore GD. 2010. Ajuba LIM proteins are negative regulators of the Hippo signaling pathway. Curr Biol 20: 657-662.
-
(2010)
Curr Biol
, vol.20
, pp. 657-662
-
-
Das Thakur, M.1
Feng, Y.2
Jagannathan, R.3
Seppa, M.J.4
Skeath, J.B.5
Longmore, G.D.6
-
28
-
-
71949111129
-
MST kinases monitor actin cytoskeletal integrity and signal via c-Jun N-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability
-
Densham RM., O'Neill E, Munro J, Konig I, Anderson K, Kolch W., Olson MF. 2009. MST kinases monitor actin cytoskeletal integrity and signal via c-Jun N-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability. Mol Cell Biol 29: 6380-6390.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 6380-6390
-
-
Densham, R.M.1
O'Neill, E.2
Munro, J.3
Konig, I.4
Anderson, K.5
Kolch, W.6
Olson, M.F.7
-
29
-
-
0025965365
-
Vasopressin depolymerizes F-actin in toad bladder epithelial cells
-
Ding GH., Franki N, Condeelis J, Hays RM. 1991. Vasopressin depolymerizes F-actin in toad bladder epithelial cells. Am J Physiol 260: C9-C16.
-
(1991)
Am J Physiol
, vol.260
-
-
Ding, G.H.1
Franki, N.2
Condeelis, J.3
Hays, R.M.4
-
30
-
-
34548636132
-
Elucidation of a universal size-control mechanism in Drosophila and mammals
-
Dong J., Feldmann G, Huang J, Wu S, Zhang N, Comerford SA, Gayyed MF., Anders RA, Maitra A, Pan D. 2007. Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 130: 1120-1133.
-
(2007)
Cell
, vol.130
, pp. 1120-1133
-
-
Dong, J.1
Feldmann, G.2
Huang, J.3
Wu, S.4
Zhang, N.5
Comerford, S.A.6
Gayyed, M.F.7
Anders, R.A.8
Maitra, A.9
Pan, D.10
-
31
-
-
33846474121
-
G-protein-coupled receptors and cancer
-
Dorsam RT., Gutkind JS. 2007. G-protein-coupled receptors and cancer. Nat Rev Cancer 7: 79-94.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 79-94
-
-
Dorsam, R.T.1
Gutkind, J.S.2
-
32
-
-
28344439885
-
A-Catenin is a molecular switch that binds E-cadherin-b-catenin and regulates actin-filament assembly
-
Drees F., Pokutta S, Yamada S, Nelson WJ, Weis WI. 2005. a-Catenin is a molecular switch that binds E-cadherin-b-catenin and regulates actin-filament assembly. Cell 123: 903-915.
-
(2005)
Cell
, vol.123
, pp. 903-915
-
-
Drees, F.1
Pokutta, S.2
Yamada, S.3
Nelson, W.J.4
Weis, W.I.5
-
33
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
Dupont S., Morsut L, Aragona M, Enzo E, Giulitti S, Cordenonsi M, Zanconato F, Le Digabel J, Forcato M, Bicciato S, et al. 2011. Role of YAP/TAZ in mechanotransduction. Nature 474: 179-183.
-
(2011)
Nature
, vol.474
, pp. 179-183
-
-
Dupont, S.1
Morsut, L.2
Aragona, M.3
Enzo, E.4
Giulitti, S.5
Cordenonsi, M.6
Zanconato, F.7
Le Digabel, J.8
Forcato, M.9
Bicciato, S.10
-
34
-
-
0025978139
-
Cell density-dependent decrease in cytoskeletal actin and myosin in cultured osteoblastic cells: Correlation with cyclic AMP changes
-
Egan JJ., Gronowicz G, Rodan GA. 1991a. Cell density-dependent decrease in cytoskeletal actin and myosin in cultured osteoblastic cells: Correlation with cyclic AMP changes. J Cell Biochem 45: 93-100.
-
(1991)
J Cell Biochem
, vol.45
, pp. 93-100
-
-
Egan, J.J.1
Gronowicz, G.2
Rodan, G.A.3
-
35
-
-
0026069186
-
Parathyroid hormone promotes the disassembly of cytoskeletal actin and myosin in cultured osteoblastic cells: Mediation by cyclic AMP
-
Egan JJ., Gronowicz G, Rodan GA. 1991b. Parathyroid hormone promotes the disassembly of cytoskeletal actin and myosin in cultured osteoblastic cells: Mediation by cyclic AMP. J Cell Biochem 45: 101-111.
-
(1991)
J Cell Biochem
, vol.45
, pp. 101-111
-
-
Egan, J.J.1
Gronowicz, G.2
Rodan, G.A.3
-
36
-
-
38049103263
-
Fat and expanded act in parallel to regulate growth through warts
-
Feng Y., Irvine KD. 2007. Fat and expanded act in parallel to regulate growth through warts. Proc Natl Acad Sci 104: 20362-20367.
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 20362-20367
-
-
Feng, Y.1
Irvine, K.D.2
-
37
-
-
72549090299
-
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
-
Fernandez LA., Northcott PA, Dalton J, Fraga C, Ellison D, Angers S., Taylor MD, Kenney AM. 2009. YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes Dev 23: 2729-2741.
-
(2009)
Genes Dev
, vol.23
, pp. 2729-2741
-
-
Fernandez, L.A.1
Northcott, P.A.2
Dalton, J.3
Fraga, C.4
Ellison, D.5
Angers, S.6
Taylor, M.D.7
Kenney, A.M.8
-
38
-
-
79956327002
-
Actin-capping protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
-
Fernandez BG., Gaspar P, Bras-Pereira C, Jezowska B, Rebelo SR, Janody F. 2011. Actin-capping protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila. Development 138: 2337-2346.
-
(2011)
Development
, vol.138
, pp. 2337-2346
-
-
Fernandez, B.G.1
Gaspar, P.2
Bras-Pereira, C.3
Jezowska, B.4
Rebelo, S.R.5
Janody, F.6
-
39
-
-
0037173716
-
Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-b/Smad signaling
-
Ferrigno O., Lallemand F, Verrecchia F, L'Hoste S, Camonis J, Atfi A., Mauviel A. 2002. Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-b/Smad signaling. Oncogene 21: 4879-4884.
-
(2002)
Oncogene
, vol.21
, pp. 4879-4884
-
-
Ferrigno, O.1
Lallemand, F.2
Verrecchia, F.3
L'Hoste, S.4
Camonis, J.5
Atfi, A.6
Mauviel, A.7
-
40
-
-
78649586402
-
Cell plasticity in homeostasis and regeneration
-
Galliot B., Ghila L. 2010. Cell plasticity in homeostasis and regeneration. Mol Reprod Dev 77: 837-855.
-
(2010)
Mol Reprod Dev
, vol.77
, pp. 837-855
-
-
Galliot, B.1
Ghila, L.2
-
41
-
-
76249093838
-
Kibra is a regulator of the Salvador/Warts/Hippo signaling network
-
Genevet A., Wehr MC, Brain R, Thompson BJ, Tapon N. 2010. Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev Cell 18: 300-308.
-
(2010)
Dev Cell
, vol.18
, pp. 300-308
-
-
Genevet, A.1
Wehr, M.C.2
Brain, R.3
Thompson, B.J.4
Tapon, N.5
-
42
-
-
84860610890
-
Regulation of epithelial-mesenchymal transition by transmission of mechanical stress through epithelial tissues
-
Gjorevski N., Boghaert E, Nelson CM. 2012. Regulation of epithelial-mesenchymal transition by transmission of mechanical stress through epithelial tissues. Cancer Microenviron 5: 29-38.
-
(2012)
Cancer Microenviron
, vol.5
, pp. 29-38
-
-
Gjorevski, N.1
Boghaert, E.2
Nelson, C.M.3
-
43
-
-
40849086201
-
SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila
-
Goulev Y., Fauny JD, Gonzalez-Marti B, Flagiello D, Silber J, Zider A. 2008. SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila. Curr Biol 18: 435-441.
-
(2008)
Curr Biol
, vol.18
, pp. 435-441
-
-
Goulev, Y.1
Fauny, J.D.2
Gonzalez-Marti, B.3
Flagiello, D.4
Silber, J.5
Zider, A.6
-
44
-
-
79151476076
-
The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster
-
Grusche FA., Degoutin JL, Richardson HE, Harvey KF. 2011. The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster. Dev Biol 350: 255-266.
-
(2011)
Dev Biol
, vol.350
, pp. 255-266
-
-
Grusche, F.A.1
Degoutin, J.L.2
Richardson, H.E.3
Harvey, K.F.4
-
45
-
-
77950485564
-
Lgl, aPKC, and Crumbs regulate the Salvador/ Warts/Hippo pathway through two distinct mechanisms
-
Grzeschik NA., Parsons LM, Allott ML, Harvey KF, Richardson HE. 2010. Lgl, aPKC, and Crumbs regulate the Salvador/ Warts/Hippo pathway through two distinct mechanisms. Curr Biol 20: 573-581.
-
(2010)
Curr Biol
, vol.20
, pp. 573-581
-
-
Grzeschik, N.A.1
Parsons, L.M.2
Allott, M.L.3
Harvey, K.F.4
Richardson, H.E.5
-
46
-
-
0035966322
-
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1
-
Habas R., Kato Y, He X. 2001. Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell 107: 843-854.
-
(2001)
Cell
, vol.107
, pp. 843-854
-
-
Habas, R.1
Kato, Y.2
He, X.3
-
47
-
-
79958182034
-
NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway
-
Habbig S., Bartram MP, Muller RU, Schwarz R, Andriopoulos N, Chen S., Sagmuller JG, Hoehne M, Burst V, Liebau MC, et al. 2011. NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway. J Cell Biol 193: 633-642.
-
(2011)
J Cell Biol
, vol.193
, pp. 633-642
-
-
Habbig, S.1
Bartram, M.P.2
Muller, R.U.3
Schwarz, R.4
Andriopoulos, N.5
Chen, S.6
Sagmuller, J.G.7
Hoehne, M.8
Burst, V.9
Liebau, M.C.10
-
48
-
-
30344445706
-
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
-
Hamaratoglu F., Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C., Jafar-Nejad H, Halder G. 2006. The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat Cell Biol 8: 27-36.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 27-36
-
-
Hamaratoglu, F.1
Willecke, M.2
Kango-Singh, M.3
Nolo, R.4
Hyun, E.5
Tao, C.6
Jafar-Nejad, H.7
Halder, G.8
-
49
-
-
41949138130
-
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
-
Hao Y., Chun A, Cheung K, Rashidi B, Yang X. 2008. Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J Biol Chem 283: 5496-5509.
-
(2008)
J Biol Chem
, vol.283
, pp. 5496-5509
-
-
Hao, Y.1
Chun, A.2
Cheung, K.3
Rashidi, B.4
Yang, X.5
-
50
-
-
0042733354
-
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
-
Harvey KF., Pfleger CM, Hariharan IK. 2003. The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell 114: 457-467.
-
(2003)
Cell
, vol.114
, pp. 457-467
-
-
Harvey, K.F.1
Pfleger, C.M.2
Hariharan, I.K.3
-
51
-
-
79955405757
-
Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size
-
Heallen T., Zhang M, Wang J, Bonilla-Claudio M, Klysik E, Johnson RL., Martin JF. 2011. Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size. Science 332: 458-461.
-
(2011)
Science
, vol.332
, pp. 458-461
-
-
Heallen, T.1
Zhang, M.2
Wang, J.3
Bonilla-Claudio, M.4
Klysik, E.5
Johnson, R.L.6
Martin, J.F.7
-
52
-
-
67650234471
-
PAR1 is selectively over expressed in high grade breast cancer patients: A cohort study
-
Hernandez NA., Correa E, Avila EP, Vela TA, Perez VM. 2009. PAR1 is selectively over expressed in high grade breast cancer patients: A cohort study. J Transl Med 7: 47.
-
(2009)
J Transl Med
, vol.7
, pp. 47
-
-
Hernandez, N.A.1
Correa, E.2
Avila, E.P.3
Vela, T.A.4
Perez, V.M.5
-
53
-
-
72649099866
-
Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila
-
Ho LL., Wei X, Shimizu T, Lai ZC. 2010. Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila. Dev Biol 337: 274-283.
-
(2010)
Dev Biol
, vol.337
, pp. 274-283
-
-
Ho, L.L.1
Wei, X.2
Shimizu, T.3
Lai, Z.C.4
-
54
-
-
79953204984
-
Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability
-
Ho KC., Zhou Z, She YM, Chun A, Cyr TD, Yang X. 2011. Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability. Proc Natl Acad Sci 108: 4870-4875.
-
(2011)
Proc Natl Acad Sci
, vol.108
, pp. 4870-4875
-
-
Ho, K.C.1
Zhou, Z.2
She, Y.M.3
Chun, A.4
Cyr, T.D.5
Yang, X.6
-
55
-
-
23644431709
-
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation
-
Hong JH., Hwang ES, McManus MT, Amsterdam A, Tian Y, Kalmukova R., Mueller E, Benjamin T, Spiegelman BM, Sharp PA, et al. 2005. TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science 309: 1074-1078.
-
(2005)
Science
, vol.309
, pp. 1074-1078
-
-
Hong, J.H.1
Hwang, E.S.2
McManus, M.T.3
Amsterdam, A.4
Tian, Y.5
Kalmukova, R.6
Mueller, E.7
Benjamin, T.8
Spiegelman, B.M.9
Sharp, P.A.10
-
56
-
-
24944436269
-
Cell tension, matrix mechanics, and cancer development
-
Huang S., Ingber DE. 2005. Cell tension, matrix mechanics, and cancer development. Cancer Cell 8: 175-176.
-
(2005)
Cancer Cell
, vol.8
, pp. 175-176
-
-
Huang, S.1
Ingber, D.E.2
-
57
-
-
23744458034
-
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP
-
Huang J., Wu S, Barrera J, Matthews K, Pan D. 2005. The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP. Cell 122: 421-434.
-
(2005)
Cell
, vol.122
, pp. 421-434
-
-
Huang, J.1
Wu, S.2
Barrera, J.3
Matthews, K.4
Pan, D.5
-
58
-
-
84876943442
-
YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14
-
doi: 10.1038/ onc.2012.231
-
Huang JM., Nagatomo I, Suzuki E, Mizuno T, Kumagai T, Berezov A., Zhang H, Karlan B, Greene MI, Wang Q. 2012. YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14. Oncogene doi: 10.1038/ onc.2012.231.
-
(2012)
Oncogene
-
-
Huang, J.M.1
Nagatomo, I.2
Suzuki, E.3
Mizuno, T.4
Kumagai, T.5
Berezov, A.6
Zhang, H.7
Karlan, B.8
Greene, M.I.9
Wang, Q.10
-
59
-
-
84864387121
-
The N-terminal phosphodegron targets TAZ/WWTR1 for SCFb-TrCP dependent degradation in response to PI3K inhibition
-
Huang W., Lv X, Liu C, Zha Z, Zhang H, Jiang Y, Xiong Y, Lei QY, Guan KL. 2012. The N-terminal phosphodegron targets TAZ/WWTR1 for SCFb-TrCP dependent degradation in response to PI3K inhibition. J Biol Chem 287: 26245-26253.
-
(2012)
J Biol Chem
, vol.287
, pp. 26245-26253
-
-
Huang, W.1
Lv, X.2
Liu, C.3
Zha, Z.4
Zhang, H.5
Jiang, Y.6
Xiong, Y.7
Lei, Q.Y.8
Guan, K.L.9
-
60
-
-
0037688016
-
Aberrant actin cytoskeleton leads to accelerated proliferation of corneal epithelial cells in mice deficient for destrin (actin depolymerizing factor)
-
Ikeda S., Cunningham LA, Boggess D, Hawes N, Hobson CD, Sundberg JP., Naggert JK, Smith RS, Nishina PM. 2003. Aberrant actin cytoskeleton leads to accelerated proliferation of corneal epithelial cells in mice deficient for destrin (actin depolymerizing factor). Hum Mol Genet 12: 1029-1037.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1029-1037
-
-
Ikeda, S.1
Cunningham, L.A.2
Boggess, D.3
Hawes, N.4
Hobson, C.D.5
Sundberg, J.P.6
Naggert, J.K.7
Smith, R.S.8
Nishina, P.M.9
-
61
-
-
73349136609
-
Hippo pathway-dependent and-independent roles of RASSF6
-
Ikeda M., Kawata A, Nishikawa M, Tateishi Y, Yamaguchi M, Nakagawa K., Hirabayashi S, Bao Y, Hidaka S, Hirata Y, et al. 2009. Hippo pathway-dependent and-independent roles of RASSF6. Sci Signal 2: ra59.
-
(2009)
Sci Signal
, vol.2
, pp. 59
-
-
Ikeda, M.1
Kawata, A.2
Nishikawa, M.3
Tateishi, Y.4
Yamaguchi, M.5
Nakagawa, K.6
Hirabayashi, S.7
Bao, Y.8
Hidaka, S.9
Hirata, Y.10
-
62
-
-
47749093500
-
Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains
-
Ishikawa HO., Takeuchi H, Haltiwanger RS, Irvine KD. 2008. Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains. Science 321: 401-404.
-
(2008)
Science
, vol.321
, pp. 401-404
-
-
Ishikawa, H.O.1
Takeuchi, H.2
Haltiwanger, R.S.3
Irvine, K.D.4
-
63
-
-
27944479854
-
Rho GTPases: Biochemistry and biology
-
Jaffe AB., Hall A. 2005. Rho GTPases: Biochemistry and biology. Annu Rev Cell Dev Biol 21: 247-269.
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 247-269
-
-
Jaffe, A.B.1
Hall, A.2
-
64
-
-
77956640978
-
TAZ as a novel enhancer of MyoD-mediated myogenic differentiation
-
Jeong H., Bae S, An SY, Byun MR, Hwang JH, Yaffe MB, Hong JH, Hwang ES. 2010. TAZ as a novel enhancer of MyoD-mediated myogenic differentiation. FASEB J 24: 3310-3320.
-
(2010)
FASEB J
, vol.24
, pp. 3310-3320
-
-
Jeong, H.1
Bae, S.2
An, S.Y.3
Byun, M.R.4
Hwang, J.H.5
Yaffe, M.B.6
Hong, J.H.7
Hwang, E.S.8
-
65
-
-
0142123293
-
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
-
Jia J., Zhang W, Wang B, Trinko R, Jiang J. 2003. The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis. Genes Dev 17: 2514-2519.
-
(2003)
Genes Dev
, vol.17
, pp. 2514-2519
-
-
Jia, J.1
Zhang, W.2
Wang, B.3
Trinko, R.4
Jiang, J.5
-
66
-
-
34547230151
-
Sveinsson chorioretinal atrophy/helicoid peripapillary chorioretinal degeneration: First histopathology report
-
Jonasson F., Hardarson S, Olafsson BM, Klintworth GK. 2007. Sveinsson chorioretinal atrophy/helicoid peripapillary chorioretinal degeneration: First histopathology report. Ophthalmology 114: 1541-1546.
-
(2007)
Ophthalmology
, vol.114
, pp. 1541-1546
-
-
Jonasson, F.1
Hardarson, S.2
Olafsson, B.M.3
Klintworth, G.K.4
-
67
-
-
0032006059
-
Microtubules and actin filaments: Dynamic targets for cancer chemotherapy
-
Jordan MA., Wilson L. 1998. Microtubules and actin filaments: Dynamic targets for cancer chemotherapy. Curr Opin Cell Biol 10: 123-130.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 123-130
-
-
Jordan, M.A.1
Wilson, L.2
-
68
-
-
84871907591
-
The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells
-
doi: 10.1242/ jcs.109546
-
Judson RN., Tremblay AM, Knopp P, White RB, Urcia R, Bari CD, Zammit PS, Camargo FD, Wackerhage H. 2012. The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells. J Cell Sci doi: 10.1242/ jcs.109546.
-
(2012)
J Cell Sci
-
-
Judson, R.N.1
Tremblay, A.M.2
Knopp, P.3
White, R.B.4
Urcia, R.5
Bari, C.D.6
Zammit, P.S.7
Camargo, F.D.8
Wackerhage, H.9
-
69
-
-
0028902594
-
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
-
Justice RW., Zilian O, Woods DF, Noll M, Bryant PJ. 1995. The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev 9: 534-546.
-
(1995)
Genes Dev
, vol.9
, pp. 534-546
-
-
Justice, R.W.1
Zilian, O.2
Woods, D.F.3
Noll, M.4
Bryant, P.J.5
-
70
-
-
17744380191
-
TAZ: A novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins
-
Kanai F., Marignani PA, Sarbassova D, Yagi R, Hall RA, Donowitz M, Hisaminato A, Fujiwara T, Ito Y, Cantley LC, et al. 2000. TAZ: A novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins. EMBO J 19: 6778-6791.
-
(2000)
EMBO J
, vol.19
, pp. 6778-6791
-
-
Kanai, F.1
Marignani, P.A.2
Sarbassova, D.3
Yagi, R.4
Hall, R.A.5
Donowitz, M.6
Hisaminato, A.7
Fujiwara, T.8
Ito, Y.9
Cantley, L.C.10
-
71
-
-
0036926950
-
Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila
-
Kango-Singh M, Nolo R, Tao C, Verstreken P, Hiesinger PR, Bellen HJ., Halder G. 2002. Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila. Development 129: 5719-5730.
-
(2002)
Development
, vol.129
, pp. 5719-5730
-
-
Kango-Singh, M.1
Nolo, R.2
Tao, C.3
Verstreken, P.4
Hiesinger, P.R.5
Bellen, H.J.6
Halder, G.7
-
72
-
-
78650202455
-
The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration
-
Karpowicz P., Perez J, Perrimon N. 2010. The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration. Development 137: 4135-4145.
-
(2010)
Development
, vol.137
, pp. 4135-4145
-
-
Karpowicz, P.1
Perez, J.2
Perrimon, N.3
-
73
-
-
0037133034
-
Identification of a novel Ras-regulated proapoptotic pathway
-
Khokhlatchev A., Rabizadeh S, Xavier R, Nedwidek M, Chen T, Zhang XF., Seed B, Avruch J. 2002. Identification of a novel Ras-regulated proapoptotic pathway. Curr Biol 12: 253-265.
-
(2002)
Curr Biol
, vol.12
, pp. 253-265
-
-
Khokhlatchev, A.1
Rabizadeh, S.2
Xavier, R.3
Nedwidek, M.4
Chen, T.5
Zhang, X.F.6
Seed, B.7
Avruch, J.8
-
74
-
-
79961087833
-
E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components
-
Kim NG., Koh E, Chen X, Gumbiner BM. 2011. E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components. Proc Natl Acad Sci 108: 11930-11935.
-
(2011)
Proc Natl Acad Sci
, vol.108
, pp. 11930-11935
-
-
Kim, N.G.1
Koh, E.2
Chen, X.3
Gumbiner, B.M.4
-
75
-
-
0242298576
-
Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1
-
Kissil JL., Wilker EW, Johnson KC, Eckman MS, Yaffe MB, Jacks T. 2003. Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1. Mol Cell 12: 841-849.
-
(2003)
Mol Cell
, vol.12
, pp. 841-849
-
-
Kissil, J.L.1
Wilker, E.W.2
Johnson, K.C.3
Eckman, M.S.4
Yaffe, M.B.5
Jacks, T.6
-
76
-
-
77957330752
-
Parasympathetic innervation maintains epithelial progenitor cells during salivary organogenesis
-
Knox SM., Lombaert IM, Reed X, Vitale-Cross L, Gutkind JS, Hoffman MP. 2010. Parasympathetic innervation maintains epithelial progenitor cells during salivary organogenesis. Science 329: 1645-1647.
-
(2010)
Science
, vol.329
, pp. 1645-1647
-
-
Knox, S.M.1
Lombaert, I.M.2
Reed, X.3
Vitale-Cross, L.4
Gutkind, J.S.5
Hoffman, M.P.6
-
77
-
-
0042858208
-
WW domaincontaining protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
-
Komuro A., Nagai M, Navin NE, Sudol M. 2003. WW domaincontaining protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. J Biol Chem 278: 33334-33341.
-
(2003)
J Biol Chem
, vol.278
, pp. 33334-33341
-
-
Komuro, A.1
Nagai, M.2
Navin, N.E.3
Sudol, M.4
-
78
-
-
0037462927
-
Characterization of KIBRA, a novel WW domain-containing protein
-
Kremerskothen J., Plaas C, Buther K, Finger I, Veltel S, Matanis T, Liedtke T, Barnekow A. 2003. Characterization of KIBRA, a novel WW domain-containing protein. Biochem Biophys Res Commun 300: 862-867.
-
(2003)
Biochem Biophys Res Commun
, vol.300
, pp. 862-867
-
-
Kremerskothen, J.1
Plaas, C.2
Buther, K.3
Finger, I.4
Veltel, S.5
Matanis, T.6
Liedtke, T.7
Barnekow, A.8
-
79
-
-
14844297327
-
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats
-
Lai ZC, Wei X, Shimizu T, Ramos E, Rohrbaugh M, Nikolaidis N, Ho LL., Li Y. 2005. Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 120: 675-685.
-
(2005)
Cell
, vol.120
, pp. 675-685
-
-
Lai, Z.C.1
Wei, X.2
Shimizu, T.3
Ramos, E.4
Rohrbaugh, M.5
Nikolaidis, N.6
Ho, L.L.7
Li, Y.8
-
80
-
-
84866274900
-
The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
-
Lamar JM., Stern P, Liu H, Schindler JW, Jiang ZG, Hynes RO. 2012. The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain. Proc Natl Acad Sci 109: E2441-E2450.
-
(2012)
Proc Natl Acad Sci
, vol.109
-
-
Lamar, J.M.1
Stern, P.2
Liu, H.3
Schindler, J.W.4
Jiang, Z.G.5
Hynes, R.O.6
-
82
-
-
78650845707
-
G protein-coupled receptors: Novel targets for drug discovery in cancer
-
Lappano R., Maggiolini M. 2011. G protein-coupled receptors: Novel targets for drug discovery in cancer. Nat Rev Drug Discov 10: 47-60.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 47-60
-
-
Lappano, R.1
Maggiolini, M.2
-
83
-
-
42449101282
-
A crucial role of WW45 in developing epithelial tissues in the mouse
-
Lee JH., Kim TS, Yang TH, Koo BK, Oh SP, Lee KP, Oh HJ, Lee SH, Kong YY, Kim JM, et al. 2008. A crucial role of WW45 in developing epithelial tissues in the mouse. EMBO J 27: 1231-1242.
-
(2008)
EMBO J
, vol.27
, pp. 1231-1242
-
-
Lee, J.H.1
Kim, T.S.2
Yang, T.H.3
Koo, B.K.4
Oh, S.P.5
Lee, K.P.6
Oh, H.J.7
Lee, S.H.8
Kong, Y.Y.9
Kim, J.M.10
-
84
-
-
77952336576
-
The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
-
Lee KP., Lee JH, Kim TS, Kim TH, Park HD, Byun JS, Kim MC, Jeong WI., Calvisi DF, Kim JM, et al. 2010. The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis. Proc Natl Acad Sci 107: 8248-8253.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 8248-8253
-
-
Lee, K.P.1
Lee, J.H.2
Kim, T.S.3
Kim, T.H.4
Park, H.D.5
Byun, J.S.6
Kim, M.C.7
Jeong, W.I.8
Calvisi, D.F.9
Kim, J.M.10
-
85
-
-
41149098966
-
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
-
Lei QY., Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL. 2008. TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol 28: 2426-2436.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 2426-2436
-
-
Lei, Q.Y.1
Zhang, H.2
Zhao, B.3
Zha, Z.Y.4
Bai, F.5
Pei, X.H.6
Zhao, S.7
Xiong, Y.8
Guan, K.L.9
-
86
-
-
54549102288
-
Beyond polymer polarity: How the cytoskeleton builds a polarized cell
-
Li R., Gundersen GG. 2008. Beyond polymer polarity: How the cytoskeleton builds a polarized cell. Nat Rev Mol Cell Biol 9: 860-873.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 860-873
-
-
Li, R.1
Gundersen, G.G.2
-
87
-
-
76149138881
-
Structural insights into the YAP and TEAD complex
-
Li Z., Zhao B, Wang P, Chen F, Dong Z, Yang H, Guan KL, Xu Y. 2010. Structural insights into the YAP and TEAD complex. Genes Dev 24: 235-240.
-
(2010)
Genes Dev
, vol.24
, pp. 235-240
-
-
Li, Z.1
Zhao, B.2
Wang, P.3
Chen, F.4
Dong, Z.5
Yang, H.6
Guan, K.L.7
Xu, Y.8
-
88
-
-
77953040994
-
The role of YAP transcription coactivator in regulating stem cell selfrenewal and differentiation
-
Lian I., Kim J, Okazawa H, Zhao J, Zhao B, Yu J, Chinnaiyan A, Israel MA., Goldstein LS, Abujarour R, et al. 2010. The role of YAP transcription coactivator in regulating stem cell selfrenewal and differentiation. Genes Dev 24: 1106-1118.
-
(2010)
Genes Dev
, vol.24
, pp. 1106-1118
-
-
Lian, I.1
Kim, J.2
Okazawa, H.3
Zhao, J.4
Zhao, B.5
Yu, J.6
Chinnaiyan, A.7
Israel, M.A.8
Goldstein, L.S.9
Abujarour, R.10
-
89
-
-
77953738883
-
The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
-
Ling C., Zheng Y, Yin F, Yu J, Huang J, Hong Y, Wu S, Pan D. 2010. The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci 107: 10532-10537.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 10532-10537
-
-
Ling, C.1
Zheng, Y.2
Yin, F.3
Yu, J.4
Huang, J.5
Hong, Y.6
Wu, S.7
Pan, D.8
-
90
-
-
65649132676
-
Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases
-
Liu S., Umezu-Goto M, Murph M, Lu Y, Liu W, Zhang F, Yu S, Stephens LC., Cui X, Murrow G, et al. 2009. Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases. Cancer Cell 15: 539-550.
-
(2009)
Cancer Cell
, vol.15
, pp. 539-550
-
-
Liu, S.1
Umezu-Goto, M.2
Murph, M.3
Lu, Y.4
Liu, W.5
Zhang, F.6
Yu, S.7
Stephens, L.C.8
Cui, X.9
Murrow, G.10
-
91
-
-
78549275131
-
The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCFb-TrCP E3 ligase
-
Liu CY., Zha ZY, Zhou X, Zhang H, Huang W, Zhao D, Li T, Chan SW., Lim CJ, Hong W, et al. 2010. The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCFb-TrCP E3 ligase. J Biol Chem 285: 37159-37169.
-
(2010)
J Biol Chem
, vol.285
, pp. 37159-37169
-
-
Liu, C.Y.1
Zha, Z.Y.2
Zhou, X.3
Zhang, H.4
Huang, W.5
Zhao, D.6
Li, T.7
Chan, S.W.8
Lim, C.J.9
Hong, W.10
-
92
-
-
77749309902
-
LPA induces osteoblast differentiation through interplay of two receptors: LPA1 and LPA4
-
Liu YB., Kharode Y, Bodine PV, Yaworsky PJ, Robinson JA, Billiard J. 2010. LPA induces osteoblast differentiation through interplay of two receptors: LPA1 and LPA4. J Cell Biochem 109: 794-800.
-
(2010)
J Cell Biochem
, vol.109
, pp. 794-800
-
-
Liu, Y.B.1
Kharode, Y.2
Bodine, P.V.3
Yaworsky, P.J.4
Robinson, J.A.5
Billiard, J.6
-
93
-
-
84874767303
-
PTPN14 interacts with and negatively regulates the oncogenic function of YAP
-
doi: 10.1038/ onc.2012.147
-
Liu X., Yang N, Figel SA, Wilson KE, Morrison CD, Gelman IH, Zhang J. 2012. PTPN14 interacts with and negatively regulates the oncogenic function of YAP. Oncogene doi: 10.1038/ onc.2012.147.
-
(2012)
Oncogene
-
-
Liu, X.1
Yang, N.2
Figel, S.A.3
Wilson, K.E.4
Morrison, C.D.5
Gelman, I.H.6
Zhang, J.7
-
94
-
-
76549124517
-
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver
-
Lu L., Li Y, Kim SM, Bossuyt W, Liu P, Qiu Q, Wang Y, Halder G, Finegold MJ., Lee JS, et al. 2010. Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc Natl Acad Sci 107: 1437-1442.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 1437-1442
-
-
Lu, L.1
Li, Y.2
Kim, S.M.3
Bossuyt, W.4
Liu, P.5
Qiu, Q.6
Wang, Y.7
Halder, G.8
Finegold, M.J.9
Lee, J.S.10
-
95
-
-
0025748166
-
The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily
-
Mahoney PA., Weber U, Onofrechuk P, Biessmann H, Bryant PJ, Goodman CS. 1991. The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily. Cell 67: 853-868.
-
(1991)
Cell
, vol.67
, pp. 853-868
-
-
Mahoney, P.A.1
Weber, U.2
Onofrechuk, P.3
Biessmann, H.4
Bryant, P.J.5
Goodman, C.S.6
-
96
-
-
70349912183
-
Drosophila lowfat, a novel modulator of Fat signaling
-
Mao Y., Kucuk B, Irvine KD. 2009. Drosophila lowfat, a novel modulator of Fat signaling. Development 136: 3223-3233.
-
(2009)
Development
, vol.136
, pp. 3223-3233
-
-
Mao, Y.1
Kucuk, B.2
Irvine, K.D.3
-
97
-
-
79951532109
-
Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development
-
Mao Y., Mulvaney J, Zakaria S, Yu T, Morgan KM, Allen S, Basson MA., Francis-West P, Irvine KD. 2011. Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development. Development 138: 947-957.
-
(2011)
Development
, vol.138
, pp. 947-957
-
-
Mao, Y.1
Mulvaney, J.2
Zakaria, S.3
Yu, T.4
Morgan, K.M.5
Allen, S.6
Basson, M.A.7
Francis-West, P.8
Irvine, K.D.9
-
98
-
-
84655169623
-
Epithelial cell polarity, stem cells and cancer
-
Martin-Belmonte F, Perez-Moreno M. 2012. Epithelial cell polarity, stem cells and cancer. Nat Rev Cancer 12: 23-38.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 23-38
-
-
Martin-Belmonte, F.1
Perez-Moreno, M.2
-
99
-
-
4444240972
-
Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing
-
Matakatsu H., Blair SS. 2004. Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing. Development 131: 3785-3794.
-
(2004)
Development
, vol.131
, pp. 3785-3794
-
-
Matakatsu, H.1
Blair, S.S.2
-
100
-
-
52049093202
-
The DHHC palmitoyltransferase approximated regulates Fat signaling and Dachs localization and activity
-
Matakatsu H., Blair SS. 2008. The DHHC palmitoyltransferase approximated regulates Fat signaling and Dachs localization and activity. Curr Biol 18: 1390-1395.
-
(2008)
Curr Biol
, vol.18
, pp. 1390-1395
-
-
Matakatsu, H.1
Blair, S.S.2
-
101
-
-
1842426730
-
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
-
McBeath R., Pirone DM, Nelson CM, Bhadriraju K, Chen CS. 2004. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell 6: 483-495.
-
(2004)
Dev Cell
, vol.6
, pp. 483-495
-
-
McBeath, R.1
Pirone, D.M.2
Nelson, C.M.3
Bhadriraju, K.4
Chen, C.S.5
-
102
-
-
0034033896
-
The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation
-
McCartney BM., Kulikauskas RM, LaJeunesse DR, Fehon RG. 2000. The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation. Development 127: 1315-1324.
-
(2000)
Development
, vol.127
, pp. 1315-1324
-
-
McCartney, B.M.1
Kulikauskas, R.M.2
LaJeunesse, D.R.3
Fehon, R.G.4
-
103
-
-
77955971943
-
A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway
-
Menendez J., Perez-Garijo A, Calleja M, Morata G. 2010. A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway. Proc Natl Acad Sci 107: 14651-14656.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 14651-14656
-
-
Menendez, J.1
Perez-Garijo, A.2
Calleja, M.3
Morata, G.4
-
104
-
-
19344363250
-
Pathophysiological roles of G-protein-coupled receptor kinases
-
Metaye T., Gibelin H, Perdrisot R, Kraimps JL. 2005. Pathophysiological roles of G-protein-coupled receptor kinases. Cell Signal 17: 917-928.
-
(2005)
Cell Signal
, vol.17
, pp. 917-928
-
-
Metaye, T.1
Gibelin, H.2
Perdrisot, R.3
Kraimps, J.L.4
-
105
-
-
84865455267
-
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP
-
Miller E., Yang J, Deran M, Wu C, Su AI, Bonamy GM, Liu J, Peters EC., Wu X. 2012. Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chem Biol 19: 955-962.
-
(2012)
Chem Biol
, vol.19
, pp. 955-962
-
-
Miller, E.1
Yang, J.2
Deran, M.3
Wu, C.4
Su, A.I.5
Bonamy, G.M.6
Liu, J.7
Peters, E.C.8
Wu, X.9
-
106
-
-
84867182034
-
Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)
-
Mo JS., Yu FX, Gong R, Brown JH, Guan KL. 2012. Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs). Genes Dev 26: 2138-2143.
-
(2012)
Genes Dev
, vol.26
, pp. 2138-2143
-
-
Mo, J.S.1
Yu, F.X.2
Gong, R.3
Brown, J.H.4
Guan, K.L.5
-
107
-
-
33645224114
-
Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65
-
Morin-Kensicki EM, Boone BN, Howell M, Stonebraker JR, Teed J, Alb JG, Magnuson TR, O'Neal W, Milgram SL. 2006. Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65. Mol Cell Biol 26: 77-87.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 77-87
-
-
Morin-Kensicki, E.M.1
Boone, B.N.2
Howell, M.3
Stonebraker, J.R.4
Teed, J.5
Alb, J.G.6
Magnuson, T.R.7
O'Neal, W.8
Milgram, S.L.9
-
108
-
-
0033305063
-
Intracellular mechanisms involved in dopamine-induced actin cytoskeleton organization and maintenance of a round phenotype in cultured rat lactotrope cells
-
Nguyen B., Carbajal ME, Vitale ML. 1999. Intracellular mechanisms involved in dopamine-induced actin cytoskeleton organization and maintenance of a round phenotype in cultured rat lactotrope cells. Endocrinology 140: 3467-3477.
-
(1999)
Endocrinology
, vol.140
, pp. 3467-3477
-
-
Nguyen, B.1
Carbajal, M.E.2
Vitale, M.L.3
-
109
-
-
84883488932
-
LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap
-
doi: 10.1038/onc.2012.431
-
Nguyen HB., Babcock JT, Wells CD, Quilliam LA. 2012. LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap. Oncogene doi: 10.1038/onc.2012.431.
-
(2012)
Oncogene
-
-
Nguyen, H.B.1
Babcock, J.T.2
Wells, C.D.3
Quilliam, L.A.4
-
110
-
-
84870572443
-
Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice
-
Nishio M., Hamada K, Kawahara K, Sasaki M, Noguchi F, Chiba S, Mizuno K, Suzuki SO, Dong Y, Tokuda M, et al. 2012. Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. J Clin Invest 122: 4505-4518.
-
(2012)
J Clin Invest
, vol.122
, pp. 4505-4518
-
-
Nishio, M.1
Hamada, K.2
Kawahara, K.3
Sasaki, M.4
Noguchi, F.5
Chiba, S.6
Mizuno, K.7
Suzuki, S.O.8
Dong, Y.9
Tokuda, M.10
-
111
-
-
61749092595
-
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass
-
Nishioka N., Inoue K, Adachi K, Kiyonari H, Ota M, Ralston A, Yabuta N., Hirahara S, Stephenson RO, Ogonuki N, et al. 2009. The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell 16: 398-410.
-
(2009)
Dev Cell
, vol.16
, pp. 398-410
-
-
Nishioka, N.1
Inoue, K.2
Adachi, K.3
Kiyonari, H.4
Ota, M.5
Ralston, A.6
Yabuta, N.7
Hirahara, S.8
Stephenson, R.O.9
Ogonuki, N.10
-
112
-
-
42549092233
-
In vivo regulation of Yorkie phosphorylation and localization
-
Oh H., Irvine KD. 2008. In vivo regulation of Yorkie phosphorylation and localization. Development 135: 1081-1088.
-
(2008)
Development
, vol.135
, pp. 1081-1088
-
-
Oh, H.1
Irvine, K.D.2
-
113
-
-
55549098921
-
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
-
Oka T., Mazack V, Sudol M. 2008. Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). J Biol Chem 283: 27534-27546.
-
(2008)
J Biol Chem
, vol.283
, pp. 27534-27546
-
-
Oka, T.1
Mazack, V.2
Sudol, M.3
-
114
-
-
78649892579
-
Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling
-
Oka T., Remue E, Meerschaert K, Vanloo B, Boucherie C, Gfeller D, Bader GD, Sidhu SS, Vandekerckhove J, Gettemans J, et al. 2010. Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling. Biochem J 432: 461-472.
-
(2010)
Biochem J
, vol.432
, pp. 461-472
-
-
Oka, T.1
Remue, E.2
Meerschaert, K.3
Vanloo, B.4
Boucherie, C.5
Gfeller, D.6
Bader, G.D.7
Sidhu, S.S.8
Vandekerckhove, J.9
Gettemans, J.10
-
115
-
-
1542358888
-
Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level
-
Omerovic J., Puggioni EM, Napoletano S, Visco V, Fraioli R, Frati L, Gulino A, Alimandi M. 2004. Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level. Exp Cell Res 294: 469-479.
-
(2004)
Exp Cell Res
, vol.294
, pp. 469-479
-
-
Omerovic, J.1
Puggioni, E.M.2
Napoletano, S.3
Visco, V.4
Fraioli, R.5
Frati, L.6
Gulino, A.7
Alimandi, M.8
-
116
-
-
33747591465
-
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
-
Overholtzer M., Zhang J, Smolen GA, Muir B, Li W, Sgroi DC, Deng CX., Brugge JS, Haber DA. 2006. Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon. Proc Natl Acad Sci 103: 12405-12410.
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 12405-12410
-
-
Overholtzer, M.1
Zhang, J.2
Smolen, G.A.3
Muir, B.4
Li, W.5
Sgroi, D.C.6
Deng, C.X.7
Brugge, J.S.8
Haber, D.A.9
-
117
-
-
77957883342
-
The hippo signaling pathway in development and cancer
-
Pan D. 2010. The hippo signaling pathway in development and cancer. Dev Cell 19: 491-505.
-
(2010)
Dev Cell
, vol.19
, pp. 491-505
-
-
Pan, D.1
-
118
-
-
0141505119
-
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
-
Pantalacci S., Tapon N, Leopold P. 2003. The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila. Nat Cell Biol 5: 921-927.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 921-927
-
-
Pantalacci, S.1
Tapon, N.2
Leopold, P.3
-
119
-
-
80053363788
-
Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor
-
Paramasivam M., Sarkeshik A, Yates JR 3rd, Fernandes MJ, McCollum D. 2011. Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor. Mol Biol Cell 22: 3725-3733.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3725-3733
-
-
Paramasivam, M.1
Sarkeshik, A.2
Yates III, J.R.3
Fernandes, M.J.4
McCollum, D.5
-
120
-
-
0030725173
-
The thyrotropin receptor in thyroid diseases
-
Paschke R., Ludgate M. 1997. The thyrotropin receptor in thyroid diseases. N Engl J Med 337: 1675-1681.
-
(1997)
N Engl J Med
, vol.337
, pp. 1675-1681
-
-
Paschke, R.1
Ludgate, M.2
-
121
-
-
44449113934
-
Cell turnover and adult tissue homeostasis: From humans to planarians
-
Pellettieri J., Sanchez Alvarado A. 2007. Cell turnover and adult tissue homeostasis: From humans to planarians. Annu Rev Genet 41: 83-105.
-
(2007)
Annu Rev Genet
, vol.41
, pp. 83-105
-
-
Pellettieri, J.1
Sanchez Alvarado, A.2
-
122
-
-
33750459738
-
Catenins: Keeping cells from getting their signals crossed
-
Perez-Moreno M, Fuchs E. 2006. Catenins: Keeping cells from getting their signals crossed. Dev Cell 11: 601-612.
-
(2006)
Dev Cell
, vol.11
, pp. 601-612
-
-
Perez-Moreno, M.1
Fuchs, E.2
-
123
-
-
84857993243
-
Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation
-
Poernbacher I., Baumgartner R, Marada SK, Edwards K, Stocker H. 2012. Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation. Curr Biol 22: 389-396.
-
(2012)
Curr Biol
, vol.22
, pp. 389-396
-
-
Poernbacher, I.1
Baumgartner, R.2
Marada, S.K.3
Edwards, K.4
Stocker, H.5
-
124
-
-
33845426464
-
The Drosophila RASSF homolog antagonizes the hippo pathway
-
Polesello C., Huelsmann S, Brown NH, Tapon N. 2006. The Drosophila RASSF homolog antagonizes the hippo pathway. Curr Biol 16: 2459-2465.
-
(2006)
Curr Biol
, vol.16
, pp. 2459-2465
-
-
Polesello, C.1
Huelsmann, S.2
Brown, N.H.3
Tapon, N.4
-
125
-
-
80755129129
-
The sterile 20-like kinase Tao-1 controls tissue growth by regulating the Salvador-Warts-Hippo pathway
-
Poon CL., Lin JI, Zhang X, Harvey KF. 2011. The sterile 20-like kinase Tao-1 controls tissue growth by regulating the Salvador-Warts-Hippo pathway. Dev Cell 21: 896-906.
-
(2011)
Dev Cell
, vol.21
, pp. 896-906
-
-
Poon, C.L.1
Lin, J.I.2
Zhang, X.3
Harvey, K.F.4
-
126
-
-
3242794878
-
Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
-
Praskova M., Khoklatchev A, Ortiz-Vega S, Avruch J. 2004. Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras. Biochem J 381: 453-462.
-
(2004)
Biochem J
, vol.381
, pp. 453-462
-
-
Praskova, M.1
Khoklatchev, A.2
Ortiz-Vega, S.3
Avruch, J.4
-
127
-
-
40149111984
-
MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation
-
Praskova M., Xia F, Avruch J. 2008. MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation. Curr Biol 18: 311-321.
-
(2008)
Curr Biol
, vol.18
, pp. 311-321
-
-
Praskova, M.1
Xia, F.2
Avruch, J.3
-
128
-
-
80054997116
-
Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma
-
Prickett TD., Wei X, Cardenas-Navia I, Teer JK, Lin JC, Walia V, Gartner J., Jiang J, Cherukuri PF, Molinolo A, et al. 2011. Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma. Nat Genet 43: 1119-1126.
-
(2011)
Nat Genet
, vol.43
, pp. 1119-1126
-
-
Prickett, T.D.1
Wei, X.2
Cardenas-Navia, I.3
Teer, J.K.4
Lin, J.C.5
Walia, V.6
Gartner, J.7
Jiang, J.8
Cherukuri, P.F.9
Molinolo, A.10
-
129
-
-
79953148385
-
Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling
-
Provenzano PP., Keely PJ. 2011. Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling. J Cell Sci 124: 1195-1205.
-
(2011)
J Cell Sci
, vol.124
, pp. 1195-1205
-
-
Provenzano, P.P.1
Keely, P.J.2
-
130
-
-
84859235472
-
Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming
-
Qin H., Blaschke K, Wei G, Ohi Y, Blouin L, Qi Z, Yu J, Yeh RF, Hebrok M., Ramalho-Santos M. 2012. Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming. Hum Mol Genet 21: 2054-2067.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 2054-2067
-
-
Qin, H.1
Blaschke, K.2
Wei, G.3
Ohi, Y.4
Blouin, L.5
Qi, Z.6
Yu, J.7
Yeh, R.F.8
Hebrok, M.9
Ramalho-Santos, M.10
-
131
-
-
77951230425
-
Formation and disassembly of adherens and tight junctions in the corneal endothelium: Regulation by actomyosin contraction
-
Ramachandran C., Srinivas SP. 2010. Formation and disassembly of adherens and tight junctions in the corneal endothelium: Regulation by actomyosin contraction. Invest Ophthalmol Vis Sci 51: 2139-2148.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 2139-2148
-
-
Ramachandran, C.1
Srinivas, S.P.2
-
132
-
-
79959808360
-
Zyxin links fat signaling to the hippo pathway
-
Rauskolb C., Pan G, Reddy BV, Oh H, Irvine KD. 2011. Zyxin links fat signaling to the hippo pathway. PLoS Biol 9: e1000624.
-
(2011)
PLoS Biol
, vol.9
-
-
Rauskolb, C.1
Pan, G.2
Reddy, B.V.3
Oh, H.4
Irvine, K.D.5
-
133
-
-
77957131890
-
TAZ interacts with zonula occludens-1 and-2 proteins in a PDZ-1 dependent manner
-
Remue E., Meerschaert K, Oka T, Boucherie C, Vandekerckhove J, Sudol M, Gettemans J. 2010. TAZ interacts with zonula occludens-1 and-2 proteins in a PDZ-1 dependent manner. FEBS Lett 584: 4175-4180.
-
(2010)
FEBS Lett
, vol.584
, pp. 4175-4180
-
-
Remue, E.1
Meerschaert, K.2
Oka, T.3
Boucherie, C.4
Vandekerckhove, J.5
Sudol, M.6
Gettemans, J.7
-
134
-
-
78650471357
-
Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways
-
Ren F., Wang B, Yue T, Yun EY, Ip YT, Jiang J. 2010a. Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways. Proc Natl Acad Sci 107: 21064-21069.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 21064-21069
-
-
Ren, F.1
Wang, B.2
Yue, T.3
Yun, E.Y.4
Ip, Y.T.5
Jiang, J.6
-
135
-
-
72649088969
-
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms
-
Ren F., Zhang L, Jiang J. 2010b. Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms. Dev Biol 337: 303-312.
-
(2010)
Dev Biol
, vol.337
, pp. 303-312
-
-
Ren, F.1
Zhang, L.2
Jiang, J.3
-
136
-
-
77955988806
-
Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling
-
Ribeiro PS., Josue F, Wepf A, Wehr MC, Rinner O, Kelly G, Tapon N, Gstaiger M. 2010. Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling. Mol Cell 39: 521-534.
-
(2010)
Mol Cell
, vol.39
, pp. 521-534
-
-
Ribeiro, P.S.1
Josue, F.2
Wepf, A.3
Wehr, M.C.4
Rinner, O.5
Kelly, G.6
Tapon, N.7
Gstaiger, M.8
-
137
-
-
77950478873
-
Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded
-
Robinson BS., Huang J, Hong Y, Moberg KH. 2010. Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr Biol 20: 582-590.
-
(2010)
Curr Biol
, vol.20
, pp. 582-590
-
-
Robinson, B.S.1
Huang, J.2
Hong, Y.3
Moberg, K.H.4
-
138
-
-
48749101754
-
Morphogen control of wing growth through the Fat signaling pathway
-
Rogulja D., Rauskolb C, Irvine KD. 2008. Morphogen control of wing growth through the Fat signaling pathway. Dev Cell 15: 309-321.
-
(2008)
Dev Cell
, vol.15
, pp. 309-321
-
-
Rogulja, D.1
Rauskolb, C.2
Irvine, K.D.3
-
139
-
-
0031657201
-
Vasopressininduced disruption of actin cytoskeletal organization and canalicular function in isolated rat hepatocyte couplets: Possible involvement of protein kinase C
-
Roma MG., Stone V, Shaw R, Coleman R. 1998. Vasopressininduced disruption of actin cytoskeletal organization and canalicular function in isolated rat hepatocyte couplets: Possible involvement of protein kinase C. Hepatology 28: 1031-1041.
-
(1998)
Hepatology
, vol.28
, pp. 1031-1041
-
-
Roma, M.G.1
Stone, V.2
Shaw, R.3
Coleman, R.4
-
140
-
-
0027245423
-
Alteration in a new gene encoding a putative membrane-organizing protein causes neurofibromatosis type 2
-
Rouleau GA., Merel P, Lutchman M, Sanson M, Zucman J, Marineau C., Hoang-Xuan K, Demczuk S, Desmaze C, Plougastel B., et al. 1993. Alteration in a new gene encoding a putative membrane-organizing protein causes neurofibromatosis type 2. Nature 363: 515-521.
-
(1993)
Nature
, vol.363
, pp. 515-521
-
-
Rouleau, G.A.1
Merel, P.2
Lutchman, M.3
Sanson, M.4
Zucman, J.5
Marineau, C.6
Hoang-Xuan, K.7
Demczuk, S.8
Desmaze, C.9
Plougastel, B.10
-
141
-
-
0028264119
-
Evidence for the complete inactivation of the NF2 gene in themajority of sporadic meningiomas
-
Ruttledge MH., Sarrazin J, Rangaratnam S, Phelan CM, Twist E, Merel P., Delattre O, Thomas G, Nordenskjold M, Collins VP, et al. 1994. Evidence for the complete inactivation of the NF2 gene in themajority of sporadic meningiomas. Nat Genet 6: 180-184.
-
(1994)
Nat Genet
, vol.6
, pp. 180-184
-
-
Ruttledge, M.H.1
Sarrazin, J.2
Rangaratnam, S.3
Phelan, C.M.4
Twist, E.5
Merel, P.6
Delattre, O.7
Thomas, G.8
Nordenskjold, M.9
Collins, V.P.10
-
144
-
-
79958851169
-
Modulating F-actin organization induces organ growth by affecting the Hippo pathway
-
Sansores-Garcia L, Bossuyt W, Wada K, Yonemura S, Tao C, Sasaki H., Halder G. 2011. Modulating F-actin organization induces organ growth by affecting the Hippo pathway. EMBO J 30: 2325-2335.
-
(2011)
EMBO J
, vol.30
, pp. 2325-2335
-
-
Sansores-Garcia, L.1
Bossuyt, W.2
Wada, K.3
Yonemura, S.4
Tao, C.5
Sasaki, H.6
Halder, G.7
-
145
-
-
79952298459
-
Yap1 acts downstream of a-catenin to control epidermal proliferation
-
Schlegelmilch K., Mohseni M, Kirak O, Pruszak J, Rodriguez JR, Zhou D., Kreger BT, Vasioukhin V, Avruch J, Brummelkamp TR, et al. 2011. Yap1 acts downstream of a-catenin to control epidermal proliferation. Cell 144: 782-795.
-
(2011)
Cell
, vol.144
, pp. 782-795
-
-
Schlegelmilch, K.1
Mohseni, M.2
Kirak, O.3
Pruszak, J.4
Rodriguez, J.R.5
Zhou, D.6
Kreger, B.T.7
Vasioukhin, V.8
Avruch, J.9
Brummelkamp, T.R.10
-
146
-
-
78650187792
-
The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration
-
Shaw RL., Kohlmaier A, Polesello C, Veelken C, Edgar BA, Tapon N. 2010. The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration. Development 137: 4147-4158.
-
(2010)
Development
, vol.137
, pp. 4147-4158
-
-
Shaw, R.L.1
Kohlmaier, A.2
Polesello, C.3
Veelken, C.4
Edgar, B.A.5
Tapon, N.6
-
147
-
-
33750624298
-
The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway
-
Silva E., Tsatskis Y, Gardano L, Tapon N, McNeill H. 2006. The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway. Curr Biol 16: 2081-2089.
-
(2006)
Curr Biol
, vol.16
, pp. 2081-2089
-
-
Silva, E.1
Tsatskis, Y.2
Gardano, L.3
Tapon, N.4
McNeill, H.5
-
148
-
-
79957462240
-
A-Catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1
-
Silvis MR., Kreger BT, Lien WH, Klezovitch O, Rudakova GM, Camargo FD., Lantz DM, Seykora JT, Vasioukhin V. 2011. a-Catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1. Sci Signal 4: ra33.
-
(2011)
Sci Signal
, vol.4
, pp. 33
-
-
Silvis, M.R.1
Kreger, B.T.2
Lien, W.H.3
Klezovitch, O.4
Rudakova, G.M.5
Camargo, F.D.6
Lantz, D.M.7
Seykora, J.T.8
Vasioukhin, V.9
-
149
-
-
58149185543
-
Planar cell polarity signaling: From fly development to human disease
-
Simons M., Mlodzik M. 2008. Planar cell polarity signaling: From fly development to human disease. Annu Rev Genet 42: 517-540.
-
(2008)
Annu Rev Genet
, vol.42
, pp. 517-540
-
-
Simons, M.1
Mlodzik, M.2
-
150
-
-
66649130741
-
Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development
-
Skouloudaki K., Puetz M, Simons M, Courbard JR, Boehlke C, Hartleben B., Engel C, Moeller MJ, Englert C, Bollig F, et al. 2009. Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. Proc Natl Acad Sci 106: 8579-8584.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 8579-8584
-
-
Skouloudaki, K.1
Puetz, M.2
Simons, M.3
Courbard, J.R.4
Boehlke, C.5
Hartleben, B.6
Engel, C.7
Moeller, M.J.8
Englert, C.9
Bollig, F.10
-
151
-
-
0026637810
-
Organization of non-muscle myosin during early murine embryonic differentiation
-
Slager HG., Good MJ, Schaart G, Groenewoud JS, Mummery CL. 1992. Organization of non-muscle myosin during early murine embryonic differentiation. Differentiation 50: 47-56.
-
(1992)
Differentiation
, vol.50
, pp. 47-56
-
-
Slager, H.G.1
Good, M.J.2
Schaart, G.3
Groenewoud, J.S.4
Mummery, C.L.5
-
152
-
-
76549127712
-
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression
-
Song H., Mak KK, Topol L, Yun K, Hu J, Garrett L, Chen Y, Park O, Chang J, Simpson RM, et al. 2010. Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. Proc Natl Acad Sci 107: 1431-1436.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 1431-1436
-
-
Song, H.1
Mak, K.K.2
Topol, L.3
Yun, K.4
Hu, J.5
Garrett, L.6
Chen, Y.7
Park, O.8
Chang, J.9
Simpson, R.M.10
-
153
-
-
67649842389
-
Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown
-
Sopko R., Silva E, Clayton L, Gardano L, Barrios-Rodiles M, Wrana J., Varelas X, Arbouzova NI, Shaw S, Saburi S, et al. 2009. Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown. Curr Biol 19: 1112-1117.
-
(2009)
Curr Biol
, vol.19
, pp. 1112-1117
-
-
Sopko, R.1
Silva, E.2
Clayton, L.3
Gardano, L.4
Barrios-Rodiles, M.5
Wrana, J.6
Varelas, X.7
Arbouzova, N.I.8
Shaw, S.9
Saburi, S.10
-
155
-
-
77956507262
-
Warts and Yorkie mediate intestinal regeneration by influencing stem cell proliferation
-
Staley BK., Irvine KD. 2010. Warts and Yorkie mediate intestinal regeneration by influencing stem cell proliferation. Curr Biol 20: 1580-1587.
-
(2010)
Curr Biol
, vol.20
, pp. 1580-1587
-
-
Staley, B.K.1
Irvine, K.D.2
-
156
-
-
80755162531
-
Hippo signaling in Drosophila: Recent advances and insights
-
Staley BK., Irvine KD. 2012. Hippo signaling in Drosophila: Recent advances and insights. Dev Dyn 241: 3-15.
-
(2012)
Dev Dyn
, vol.241
, pp. 3-15
-
-
Staley, B.K.1
Irvine, K.D.2
-
157
-
-
53849087493
-
Expression of Yes-associated protein in common solid tumors
-
Steinhardt AA., Gayyed MF, Klein AP, Dong J, Maitra A, Pan D, Montgomery EA., Anders RA. 2008. Expression of Yes-associated protein in common solid tumors. Hum Pathol 39: 1582-1589.
-
(2008)
Hum Pathol
, vol.39
, pp. 1582-1589
-
-
Steinhardt, A.A.1
Gayyed, M.F.2
Klein, A.P.3
Dong, J.4
Maitra, A.5
Pan, D.6
Montgomery, E.A.7
Anders, R.A.8
-
158
-
-
0032907439
-
Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
-
St. John MA, Tao W, Fei X, Fukumoto R, Carcangiu ML, Brownstein DG., Parlow AF, McGrath J, Xu T. 1999. Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction. Nat Genet 21: 182-186.
-
(1999)
Nat Genet
, vol.21
, pp. 182-186
-
-
StJohn, M.A.1
Tao, W.2
Fei, X.3
Fukumoto, R.4
Carcangiu, M.L.5
Brownstein, D.G.6
Parlow, A.F.7
McGrath, J.8
Xu, T.9
-
159
-
-
0035805487
-
Physical interaction with Yes-associated protein enhances p73 transcriptional activity
-
Strano S., Munarriz E, Rossi M, Castagnoli L, Shaul Y, Sacchi A, Oren M., Sudol M, Cesareni G, Blandino G. 2001. Physical interaction with Yes-associated protein enhances p73 transcriptional activity. J Biol Chem 276: 15164-15173.
-
(2001)
J Biol Chem
, vol.276
, pp. 15164-15173
-
-
Strano, S.1
Munarriz, E.2
Rossi, M.3
Castagnoli, L.4
Shaul, Y.5
Sacchi, A.6
Oren, M.7
Sudol, M.8
Cesareni, G.9
Blandino, G.10
-
160
-
-
84862146104
-
Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP
-
Strassburger K., Tiebe M, Pinna F, Breuhahn K, Teleman AA. 2012. Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP. Dev Biol 367: 187-196.
-
(2012)
Dev Biol
, vol.367
, pp. 187-196
-
-
Strassburger, K.1
Tiebe, M.2
Pinna, F.3
Breuhahn, K.4
Teleman, A.A.5
-
161
-
-
78651261751
-
Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors
-
Sun G., Irvine KD. 2011. Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors. Dev Biol 350: 139-151.
-
(2011)
Dev Biol
, vol.350
, pp. 139-151
-
-
Sun, G.1
Irvine, K.D.2
-
162
-
-
84861658918
-
Secreted kinase phosphorylates extracellular proteins that regulate biomineralization
-
Tagliabracci VS., Engel JL, Wen J, Wiley SE, Worby CA, Kinch LN, Xiao J, Grishin NV, Dixon JE. 2012. Secreted kinase phosphorylates extracellular proteins that regulate biomineralization. Science 336: 1150-1153.
-
(2012)
Science
, vol.336
, pp. 1150-1153
-
-
Tagliabracci, V.S.1
Engel, J.L.2
Wen, J.3
Wiley, S.E.4
Worby, C.A.5
Kinch, L.N.6
Xiao, J.7
Grishin, N.V.8
Dixon, J.E.9
-
163
-
-
0037162714
-
Salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
-
Tapon N., Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber DA, Hariharan IK. 2002. salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110: 467-478.
-
(2002)
Cell
, vol.110
, pp. 467-478
-
-
Tapon, N.1
Harvey, K.F.2
Bell, D.W.3
Wahrer, D.C.4
Schiripo, T.A.5
Haber, D.A.6
Hariharan, I.K.7
-
164
-
-
0025285657
-
Crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia
-
Tepass U., Theres C, Knust E. 1990. crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia. Cell 61: 787-799.
-
(1990)
Cell
, vol.61
, pp. 787-799
-
-
Tepass, U.1
Theres, C.2
Knust, E.3
-
165
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP., Acloque H, Huang RY, Nieto MA. 2009. Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
166
-
-
84860742593
-
Organ size control by Hippo and TOR pathways
-
Tumaneng K., Russell RC, Guan KL. 2012a. Organ size control by Hippo and TOR pathways. Curr Biol 22: R368-R379.
-
(2012)
Curr Biol
, vol.22
-
-
Tumaneng, K.1
Russell, R.C.2
Guan, K.L.3
-
167
-
-
84870610975
-
YAP mediates crosstalk between the Hippo and PI(3)K-TOR pathways by suppressing PTEN via miR-29
-
Tumaneng K., Schlegelmilch K, Russell RC, Yimlamai D, Basnet H, Mahadevan N, Fitamant J, Bardeesy N, Camargo FD, Guan KL. 2012b. YAP mediates crosstalk between the Hippo and PI(3)K-TOR pathways by suppressing PTEN via miR-29. Nat Cell Biol 14: 1322-1329.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 1322-1329
-
-
Tumaneng, K.1
Schlegelmilch, K.2
Russell, R.C.3
Yimlamai, D.4
Basnet, H.5
Mahadevan, N.6
Fitamant, J.7
Bardeesy, N.8
Camargo, F.D.9
Guan, K.L.10
-
168
-
-
34247134640
-
Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways
-
Tyler DM., Baker NE. 2007. Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways. Dev Biol 305: 187-201.
-
(2007)
Dev Biol
, vol.305
, pp. 187-201
-
-
Tyler, D.M.1
Baker, N.E.2
-
169
-
-
0141616617
-
Hippo promotes proliferation arrest and apoptosis in the Salvador/ Warts pathway
-
Udan RS., Kango-Singh M, Nolo R, Tao C, Halder G. 2003. Hippo promotes proliferation arrest and apoptosis in the Salvador/ Warts pathway. Nat Cell Biol 5: 914-920.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 914-920
-
-
Udan, R.S.1
Kango-Singh, M.2
Nolo, R.3
Tao, C.4
Halder, G.5
-
170
-
-
59049107421
-
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
-
Van Raamsdonk CD, Bezrookove V, Green G, Bauer J, Gaugler L, O'Brien JM, Simpson EM, Barsh GS, Bastian BC. 2009. Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature 457: 599-602.
-
(2009)
Nature
, vol.457
, pp. 599-602
-
-
van Raamsdonk, C.D.1
Bezrookove, V.2
Green, G.3
Bauer, J.4
Gaugler, L.5
O'Brien, J.M.6
Simpson, E.M.7
Barsh, G.S.8
Bastian, B.C.9
-
171
-
-
78651446131
-
Mutations in GNA11 in uveal melanoma
-
Van Raamsdonk CD, Griewank KG, Crosby MB, Garrido MC, Vemula S., Wiesner T, Obenauf AC, Wackernagel W, Green G, Bouvier N, et al. 2010. Mutations in GNA11 in uveal melanoma. N Engl J Med 363: 2191-2199.
-
(2010)
N Engl J Med
, vol.363
, pp. 2191-2199
-
-
van Raamsdonk, C.D.1
Griewank, K.G.2
Crosby, M.B.3
Garrido, M.C.4
Vemula, S.5
Wiesner, T.6
Obenauf, A.C.7
Wackernagel, W.8
Green, G.9
Bouvier, N.10
-
172
-
-
46049087598
-
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
-
Varelas X., Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J., Yaffe MB, Zandstra PW, Wrana JL. 2008. TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nat Cell Biol 10: 837-848.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 837-848
-
-
Varelas, X.1
Sakuma, R.2
Samavarchi-Tehrani, P.3
Peerani, R.4
Rao, B.M.5
Dembowy, J.6
Yaffe, M.B.7
Zandstra, P.W.8
Wrana, J.L.9
-
173
-
-
78649969033
-
The Crumbs complex couples cell density sensing to Hippodependent control of the TGF-b-SMAD pathway
-
Varelas X., Samavarchi-Tehrani P, Narimatsu M, Weiss A, Cockburn K., Larsen BG, Rossant J, Wrana JL. 2010. The Crumbs complex couples cell density sensing to Hippodependent control of the TGF-b-SMAD pathway. Dev Cell 19: 831-844.
-
(2010)
Dev Cell
, vol.19
, pp. 831-844
-
-
Varelas, X.1
Samavarchi-Tehrani, P.2
Narimatsu, M.3
Weiss, A.4
Cockburn, K.5
Larsen, B.G.6
Rossant, J.7
Wrana, J.L.8
-
174
-
-
0035873391
-
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
-
Vassilev A., Kaneko KJ, Shu H, Zhao Y, DePamphilis ML. 2001. TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm. Genes Dev 15: 1229-1241.
-
(2001)
Genes Dev
, vol.15
, pp. 1229-1241
-
-
Vassilev, A.1
Kaneko, K.J.2
Shu, H.3
Zhao, Y.4
DePamphilis, M.L.5
-
175
-
-
80053626472
-
LATS1 tumor suppressor is a novel actin-binding protein and negative regulator of actin polymerization
-
Visser-Grieve S, Zhou Z, She YM, Huang H, Cyr TD, Xu T, Yang X. 2011. LATS1 tumor suppressor is a novel actin-binding protein and negative regulator of actin polymerization. Cell Res 21: 1513-1516.
-
(2011)
Cell Res
, vol.21
, pp. 1513-1516
-
-
Visser-Grieve, S.1
Zhou, Z.2
She, Y.M.3
Huang, H.4
Cyr, T.D.5
Xu, T.6
Yang, X.7
-
176
-
-
33645773666
-
Local force and geometry sensing regulate cell functions
-
Vogel V., Sheetz M. 2006. Local force and geometry sensing regulate cell functions. Nat Rev Mol Cell Biol 7: 265-275.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 265-275
-
-
Vogel, V.1
Sheetz, M.2
-
177
-
-
84857136357
-
YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy
-
von Gise A, Lin Z, Schlegelmilch K, Honor LB, Pan GM, Buck JN, Ma Q, Ishiwata T, Zhou B, Camargo FD, et al. 2012. YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy. Proc Natl Acad Sci 109: 2394-2399.
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 2394-2399
-
-
von Gise, A.1
Lin, Z.2
Schlegelmilch, K.3
Honor, L.B.4
Pan, G.M.5
Buck, J.N.6
Ma, Q.7
Ishiwata, T.8
Zhou, B.9
Camargo, F.D.10
-
178
-
-
80051923057
-
Hippo pathway regulation by cell morphology and stress fibers
-
Wada K., Itoga K, Okano T, Yonemura S, Sasaki H. 2011. Hippo pathway regulation by cell morphology and stress fibers. Development 138: 3907-3914.
-
(2011)
Development
, vol.138
, pp. 3907-3914
-
-
Wada, K.1
Itoga, K.2
Okano, T.3
Yonemura, S.4
Sasaki, H.5
-
179
-
-
79953010044
-
Angiomotin-like proteins associate with and negatively regulate YAP1
-
Wang W., Huang J, Chen J. 2011. Angiomotin-like proteins associate with and negatively regulate YAP1. J Biol Chem 286: 4364-4370.
-
(2011)
J Biol Chem
, vol.286
, pp. 4364-4370
-
-
Wang, W.1
Huang, J.2
Chen, J.3
-
180
-
-
84865840957
-
PTPN14 is required for the density-dependent control of YAP1
-
Wang W., Huang J, Wang X, Yuan J, Li X, Feng L, Park JI, Chen J. 2012. PTPN14 is required for the density-dependent control of YAP1. Genes Dev 26: 1959-1971.
-
(2012)
Genes Dev
, vol.26
, pp. 1959-1971
-
-
Wang, W.1
Huang, J.2
Wang, X.3
Yuan, J.4
Li, X.5
Feng, L.6
Park, J.I.7
Chen, J.8
-
181
-
-
77949487623
-
Yap is a novel regulator of C2C12 myogenesis
-
Watt KI., Judson R, Medlow P, Reid K, Kurth TB, Burniston JG, Ratkevicius A., De Bari C, Wackerhage H. 2010. Yap is a novel regulator of C2C12 myogenesis. Biochem Biophys Res Commun 393: 619-624.
-
(2010)
Biochem Biophys Res Commun
, vol.393
, pp. 619-624
-
-
Watt, K.I.1
Judson, R.2
Medlow, P.3
Reid, K.4
Kurth, T.B.5
Burniston, J.G.6
Ratkevicius, A.7
de Bari, C.8
Wackerhage, H.9
-
182
-
-
84871721147
-
Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila
-
(in press). doi: 10.1038/ncb2658
-
Wehr MC., Holder MV, Gailite I, Saunders RE, Maile TM, Ciirdaeva E., Instrell R, Jiang M, Howell M, Rossner MJ, et al. 2012. Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila. Nat Cell Biol (in press). doi: 10.1038/ncb2658.
-
(2012)
Nat Cell Biol
-
-
Wehr, M.C.1
Holder, M.V.2
Gailite, I.3
Saunders, R.E.4
Maile, T.M.5
Ciirdaeva, E.6
Instrell, R.7
Jiang, M.8
Howell, M.9
Rossner, M.J.10
-
183
-
-
33646136870
-
A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells
-
Wells CD., Fawcett JP, Traweger A, Yamanaka Y, Goudreault M, Elder K., Kulkarni S, Gish G, Virag C, Lim C, et al. 2006. A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells. Cell 125: 535-548.
-
(2006)
Cell
, vol.125
, pp. 535-548
-
-
Wells, C.D.1
Fawcett, J.P.2
Traweger, A.3
Yamanaka, Y.4
Goudreault, M.5
Elder, K.6
Kulkarni, S.7
Gish, G.8
Virag, C.9
Lim, C.10
-
184
-
-
33750614445
-
The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size
-
Willecke M., Hamaratoglu F, Kango-Singh M, Udan R, Chen CL, Tao C., Zhang X, Halder G. 2006. The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size. Curr Biol 16: 2090-2100.
-
(2006)
Curr Biol
, vol.16
, pp. 2090-2100
-
-
Willecke, M.1
Hamaratoglu, F.2
Kango-Singh, M.3
Udan, R.4
Chen, C.L.5
Tao, C.6
Zhang, X.7
Halder, G.8
-
185
-
-
54449090287
-
Boundaries of Dachsous cadherin activity modulate the Hippo signaling pathway to induce cell proliferation
-
Willecke M., Hamaratoglu F, Sansores-Garcia L, Tao C, Halder G. 2008. Boundaries of Dachsous cadherin activity modulate the Hippo signaling pathway to induce cell proliferation. Proc Natl Acad Sci 105: 14897-14902.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 14897-14902
-
-
Willecke, M.1
Hamaratoglu, F.2
Sansores-Garcia, L.3
Tao, C.4
Halder, G.5
-
186
-
-
0042232429
-
Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
-
Wu S., Huang J, Dong J, Pan D. 2003. hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell 114: 445-456.
-
(2003)
Cell
, vol.114
, pp. 445-456
-
-
Wu, S.1
Huang, J.2
Dong, J.3
Pan, D.4
-
187
-
-
42049116586
-
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
-
Wu S., Liu Y, Zheng Y, Dong J, Pan D. 2008. The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev Cell 14: 388-398.
-
(2008)
Dev Cell
, vol.14
, pp. 388-398
-
-
Wu, S.1
Liu, Y.2
Zheng, Y.3
Dong, J.4
Pan, D.5
-
188
-
-
0028929414
-
Identifying tumor suppressors in genetic mosaics: The Drosophila lats gene encodes a putative protein kinase
-
Xu T., Wang W, Zhang S, Stewart RA, Yu W. 1995. Identifying tumor suppressors in genetic mosaics: The Drosophila lats gene encodes a putative protein kinase. Development 121: 1053-1063.
-
(1995)
Development
, vol.121
, pp. 1053-1063
-
-
Xu, T.1
Wang, W.2
Zhang, S.3
Stewart, R.A.4
Yu, W.5
-
189
-
-
70349295967
-
Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma
-
Xu MZ., Yao TJ, Lee NP, Ng IO, Chan YT, Zender L, Lowe SW, Poon RT., Luk JM. 2009. Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma. Cancer 115: 4576-4585.
-
(2009)
Cancer
, vol.115
, pp. 4576-4585
-
-
Xu, M.Z.1
Yao, T.J.2
Lee, N.P.3
Ng, I.O.4
Chan, Y.T.5
Zender, L.6
Lowe, S.W.7
Poon, R.T.8
Luk, J.M.9
-
190
-
-
0033522472
-
AWW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
-
Yagi R., Chen LF, Shigesada K, Murakami Y, Ito Y. 1999. AWW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J 18: 2551-2562.
-
(1999)
EMBO J
, vol.18
, pp. 2551-2562
-
-
Yagi, R.1
Chen, L.F.2
Shigesada, K.3
Murakami, Y.4
Ito, Y.5
-
191
-
-
45249122818
-
cAMP/PKA regulates osteogenesis, adipogenesis and ratio of RANKL/OPG mRNA expression in mesenchymal stem cells by suppressing leptin
-
Yang DC., Tsay HJ, Lin SY, Chiou SH, Li MJ, Chang TJ, Hung SC. 2008. cAMP/PKA regulates osteogenesis, adipogenesis and ratio of RANKL/OPG mRNA expression in mesenchymal stem cells by suppressing leptin. PLoS One 3: e1540.
-
(2008)
PLoS One
, vol.3
-
-
Yang, D.C.1
Tsay, H.J.2
Lin, S.Y.3
Chiou, S.H.4
Li, M.J.5
Chang, T.J.6
Hung, S.C.7
-
192
-
-
84864363253
-
Akt is negatively regulated by Hippo signaling for growth inhibition in Drosophila
-
Ye X., Deng Y, Lai ZC. 2012. Akt is negatively regulated by Hippo signaling for growth inhibition in Drosophila. Dev Biol 369: 115-123.
-
(2012)
Dev Biol
, vol.369
, pp. 115-123
-
-
Ye, X.1
Deng, Y.2
Lai, Z.C.3
-
193
-
-
79953753962
-
A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions
-
Yi C., Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N., Persson NL, Shimono A, Speicher DW, Marmorstein R., et al. 2011. A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell 19: 527-540.
-
(2011)
Cancer Cell
, vol.19
, pp. 527-540
-
-
Yi, C.1
Troutman, S.2
Fera, D.3
Stemmer-Rachamimov, A.4
Avila, J.L.5
Christian, N.6
Persson, N.L.7
Shimono, A.8
Speicher, D.W.9
Marmorstein, R.10
-
194
-
-
76249109900
-
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
-
Yu J., Zheng Y, Dong J, Klusza S, Deng WM, Pan D. 2010. Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev Cell 18: 288-299.
-
(2010)
Dev Cell
, vol.18
, pp. 288-299
-
-
Yu, J.1
Zheng, Y.2
Dong, J.3
Klusza, S.4
Deng, W.M.5
Pan, D.6
-
195
-
-
84869456501
-
Upstream regulators of the Hippo pathway
-
Yu FX., Mo JS, Guan KL. 2012a. Upstream regulators of the Hippo pathway. Cell Cycle 11: 4097-4098.
-
(2012)
Cell Cycle
, vol.11
, pp. 4097-4098
-
-
Yu, F.X.1
Mo, J.S.2
Guan, K.L.3
-
196
-
-
84865260845
-
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
-
Yu FX., Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH, Zhao J, Yuan H, Tumaneng K, Li H, et al. 2012b. Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell 150: 780-791.
-
(2012)
Cell
, vol.150
, pp. 780-791
-
-
Yu, F.X.1
Zhao, B.2
Panupinthu, N.3
Jewell, J.L.4
Lian, I.5
Wang, L.H.6
Zhao, J.7
Yuan, H.8
Tumaneng, K.9
Li, H.10
-
197
-
-
77954740913
-
A feed-forward circuit linking wingless, fat-dachsous signaling, and the warts-hippo pathway to Drosophila wing growth
-
Zecca M., Struhl G. 2010. A feed-forward circuit linking wingless, fat-dachsous signaling, and the warts-hippo pathway to Drosophila wing growth. PLoS Biol 8: e1000386.
-
(2010)
PLoS Biol
, vol.8
-
-
Zecca, M.1
Struhl, G.2
-
198
-
-
0035133266
-
Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice
-
Zhang FP., Poutanen M, Wilbertz J, Huhtaniemi I. 2001. Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice. Mol Endocrinol 15: 172-183.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 172-183
-
-
Zhang, F.P.1
Poutanen, M.2
Wilbertz, J.3
Huhtaniemi, I.4
-
199
-
-
33846405735
-
PTH-induced actin depolymerization increases mechanosensitive channel activity to enhance mechanically stimulated Ca2+ signaling in osteoblasts
-
Zhang J., Ryder KD, Bethel JA, Ramirez R, Duncan RL. 2006. PTH-induced actin depolymerization increases mechanosensitive channel activity to enhance mechanically stimulated Ca2+ signaling in osteoblasts. J Bone Miner Res 21: 1729-1737.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 1729-1737
-
-
Zhang, J.1
Ryder, K.D.2
Bethel, J.A.3
Ramirez, R.4
Duncan, R.L.5
-
200
-
-
42049120338
-
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control
-
Zhang L., Ren F, Zhang Q, Chen Y, Wang B, Jiang J. 2008. The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev Cell 14: 377-387.
-
(2008)
Dev Cell
, vol.14
, pp. 377-387
-
-
Zhang, L.1
Ren, F.2
Zhang, Q.3
Chen, Y.4
Wang, B.5
Jiang, J.6
-
201
-
-
77954945373
-
The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals
-
Zhang N., Bai H, David KK, Dong J, Zheng Y, Cai J, Giovannini M, Liu P, Anders RA, Pan D. 2010. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Dev Cell 19: 27-38.
-
(2010)
Dev Cell
, vol.19
, pp. 27-38
-
-
Zhang, N.1
Bai, H.2
David, K.K.3
Dong, J.4
Zheng, Y.5
Cai, J.6
Giovannini, M.7
Liu, P.8
Anders, R.A.9
Pan, D.10
-
202
-
-
79952297528
-
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin
-
Zhang H., Pasolli HA, Fuchs E. 2011. Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. Proc Natl Acad Sci 108: 2270-2275.
-
(2011)
Proc Natl Acad Sci
, vol.108
, pp. 2270-2275
-
-
Zhang, H.1
Pasolli, H.A.2
Fuchs, E.3
-
203
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
Zhao B., Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J., Li L, et al. 2007. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev 21: 2747-2761.
-
(2007)
Genes Dev
, vol.21
, pp. 2747-2761
-
-
Zhao, B.1
Wei, X.2
Li, W.3
Udan, R.S.4
Yang, Q.5
Kim, J.6
Xie, J.7
Ikenoue, T.8
Yu, J.9
Li, L.10
-
204
-
-
47549095853
-
TEAD mediates YAP-dependent gene induction and growth control
-
Zhao B., Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY, Chinnaiyan AM., et al. 2008. TEAD mediates YAP-dependent gene induction and growth control. Genes Dev 22: 1962-1971.
-
(2008)
Genes Dev
, vol.22
, pp. 1962-1971
-
-
Zhao, B.1
Ye, X.2
Yu, J.3
Li, L.4
Li, W.5
Li, S.6
Yu, J.7
Lin, J.D.8
Wang, C.Y.9
Chinnaiyan, A.M.10
-
205
-
-
77951837150
-
The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version
-
Zhao B., Li L, Lei Q, Guan KL. 2010a. The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version. Genes Dev 24: 862-874.
-
(2010)
Genes Dev
, vol.24
, pp. 862-874
-
-
Zhao, B.1
Li, L.2
Lei, Q.3
Guan, K.L.4
-
206
-
-
73549095761
-
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(b-TRCP)
-
Zhao B., Li L, Tumaneng K, Wang CY, Guan KL. 2010b. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(b-TRCP). Genes Dev 24: 72-85.
-
(2010)
Genes Dev
, vol.24
, pp. 72-85
-
-
Zhao, B.1
Li, L.2
Tumaneng, K.3
Wang, C.Y.4
Guan, K.L.5
-
207
-
-
78650895035
-
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
-
Zhao B., Li L, Lu Q, Wang LH, Liu CY, Lei Q, Guan KL. 2011. Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes Dev 25: 51-63.
-
(2011)
Genes Dev
, vol.25
, pp. 51-63
-
-
Zhao, B.1
Li, L.2
Lu, Q.3
Wang, L.H.4
Liu, C.Y.5
Lei, Q.6
Guan, K.L.7
-
208
-
-
84855326431
-
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
-
Zhao B., Li L, Wang L, Wang CY, Yu J, Guan KL. 2012. Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes Dev 26: 54-68.
-
(2012)
Genes Dev
, vol.26
, pp. 54-68
-
-
Zhao, B.1
Li, L.2
Wang, L.3
Wang, C.Y.4
Yu, J.5
Guan, K.L.6
-
209
-
-
70350502865
-
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
-
Zhou D., Conrad C, Xia F, Park JS, Payer B, Yin Y, Lauwers GY, Thasler W., Lee JT, Avruch J, et al. 2009. Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell 16: 425-438.
-
(2009)
Cancer Cell
, vol.16
, pp. 425-438
-
-
Zhou, D.1
Conrad, C.2
Xia, F.3
Park, J.S.4
Payer, B.5
Yin, Y.6
Lauwers, G.Y.7
Thasler, W.8
Lee, J.T.9
Avruch, J.10
-
210
-
-
83755195660
-
Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance
-
Zhou D., Zhang Y, Wu H, Barry E, Yin Y, Lawrence E, Dawson D, Willis JE., Markowitz SD, Camargo FD, et al. 2011. Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance. Proc Natl Acad Sci 108: E1312-E1320.
-
(2011)
Proc Natl Acad Sci
, vol.108
-
-
Zhou, D.1
Zhang, Y.2
Wu, H.3
Barry, E.4
Yin, Y.5
Lawrence, E.6
Dawson, D.7
Willis, J.E.8
Markowitz, S.D.9
Camargo, F.D.10
|