-
1
-
-
78651141386
-
The autonomous behaviour of normal thymus grafts
-
D. Metcalf The autonomous behaviour of normal thymus grafts Aust. J. Exp. Biol. Med. Sci. 41 Suppl 1963 437 447
-
(1963)
Aust. J. Exp. Biol. Med. Sci.
, vol.41
, Issue.SUPPL.
, pp. 437-447
-
-
Metcalf, D.1
-
2
-
-
0021918375
-
Intrinsic growth control in the imaginal primordia of Drosophila, and the autonomous action of a lethal mutation causing overgrowth
-
DOI 10.1016/0012-1606(85)90317-3
-
P.J. Bryant, and P. Levinson Intrinsic growth control in the imaginal primordia of Drosophila, and the autonomous action of a lethal mutation causing overgrowth Dev. Biol. 107 1985 355 363 (Pubitemid 15110939)
-
(1985)
Developmental Biology
, vol.107
, Issue.2
, pp. 355-363
-
-
Bryant, P.J.1
Levinson, P.2
-
3
-
-
0000130078
-
Restricted growth capacity of multiple spleen grafts
-
D. Metcalf Restricted growth capacity of multiple spleen grafts Transplantation 2 1964 387 392
-
(1964)
Transplantation
, vol.2
, pp. 387-392
-
-
Metcalf, D.1
-
4
-
-
0033672580
-
Role of retinoic acid in lens regeneration
-
P.A. Tsonis, M.T. Trombley, T. Rowland, R.A. Chandraratna, and K. del Rio-Tsonis Role of retinoic acid in lens regeneration Dev. Dyn. 219 2000 588 593
-
(2000)
Dev. Dyn.
, vol.219
, pp. 588-593
-
-
Tsonis, P.A.1
Trombley, M.T.2
Rowland, T.3
Chandraratna, R.A.4
Del Rio-Tsonis, K.5
-
5
-
-
0021661051
-
Intrinsic and extrinsic control of growth in developing organs
-
P.J. Bryant, and P. Simpson Intrinsic and extrinsic control of growth in developing organs Quart. Rev. Biol. 59 1984 387 415
-
(1984)
Quart. Rev. Biol.
, vol.59
, pp. 387-415
-
-
Bryant, P.J.1
Simpson, P.2
-
6
-
-
15244353607
-
Intestinal adaptation after massive intestinal resection
-
DOI 10.1136/pgmj.2004.023846
-
A.R. Weale, A.G. Edwards, M. Bailey, and P.A. Lear Intestinal adaptation after massive intestinal resection Postgrad. Med. J. 81 2005 178 184 (Pubitemid 40387967)
-
(2005)
Postgraduate Medical Journal
, vol.81
, Issue.953
, pp. 178-184
-
-
Weale, A.R.1
Edwards, A.G.2
Bailey, M.3
Lear, P.A.4
-
7
-
-
33847210675
-
Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver
-
B.Z. Stanger, A.J. Tanaka, and D.A. Melton Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver Nature 445 2007 886 891
-
(2007)
Nature
, vol.445
, pp. 886-891
-
-
Stanger, B.Z.1
Tanaka, A.J.2
Melton, D.A.3
-
8
-
-
0028171292
-
G1 phase progression: Cycling on cue
-
DOI 10.1016/0092-8674(94)90540-1
-
C.J. Sherr G1 phase progression: cycling on cue Cell 79 1994 551 555 (Pubitemid 24363798)
-
(1994)
Cell
, vol.79
, Issue.4
, pp. 551-555
-
-
Sherr, C.J.1
-
9
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
C.J. Sherr, and J.M. Roberts Inhibitors of mammalian G1 cyclin-dependent kinases Genes Dev. 9 1995 1149 1163
-
(1995)
Genes Dev.
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
10
-
-
0029808466
-
Cell cycle checkpoints: Preventing an identity crisis
-
DOI 10.1126/science.274.5293.1664
-
S.J. Elledge Cell cycle checkpoints: preventing an identity crisis Science 274 1996 1664 1672 (Pubitemid 26414889)
-
(1996)
Science
, vol.274
, Issue.5293
, pp. 1664-1672
-
-
Elledge, S.J.1
-
11
-
-
0028179669
-
P27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
-
K. Polyak, J.Y. Kato, M.J. Solomon, C.J. Sherr, J. Massague, J.M. Roberts, and A. Koff p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest Genes Dev. 8 1994 9 22
-
(1994)
Genes Dev.
, vol.8
, pp. 9-22
-
-
Polyak, K.1
Kato, J.Y.2
Solomon, M.J.3
Sherr, C.J.4
Massague, J.5
Roberts, J.M.6
Koff, A.7
-
12
-
-
15844415946
-
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1)
-
H. Kiyokawa, R.D. Kineman, K.O. Manova-Todorova, V.C. Soares, E.S. Hoffman, M. Ono, D. Khanam, A.C. Hayday, L.A. Frohman, and A. Koff Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1) Cell 85 1996 721 732
-
(1996)
Cell
, vol.85
, pp. 721-732
-
-
Kiyokawa, H.1
Kineman, R.D.2
Manova-Todorova, K.O.3
Soares, V.C.4
Hoffman, E.S.5
Ono, M.6
Khanam, D.7
Hayday, A.C.8
Frohman, L.A.9
Koff, A.10
-
13
-
-
0030010591
-
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
K. Nakayama, N. Ishida, M. Shirane, A. Inomata, T. Inoue, N. Shishido, I. Horii, D.Y. Loh, and K. Nakayama Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors Cell 85 1996 707 720
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
Inomata, A.4
Inoue, T.5
Shishido, N.6
Horii, I.7
Loh, D.Y.8
Nakayama, K.9
-
14
-
-
15844384256
-
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice
-
M.L. Fero, M. Rivkin, M. Tasch, P. Porter, C.E. Carow, E. Firpo, K. Polyak, L.H. Tsai, V. Broudy, and R.M. Perlmutter A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice Cell 85 1996 733 744
-
(1996)
Cell
, vol.85
, pp. 733-744
-
-
Fero, M.L.1
Rivkin, M.2
Tasch, M.3
Porter, P.4
Carow, C.E.5
Firpo, E.6
Polyak, K.7
Tsai, L.H.8
Broudy, V.9
Perlmutter, R.M.10
-
15
-
-
0037135177
-
Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
-
DOI 10.1126/science.1074192
-
A. Chenn, and C.A. Walsh Regulation of cerebral cortical size by control of cell cycle exit in neural precursors Science 297 2002 365 369 (Pubitemid 34790759)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 365-369
-
-
Chenn, A.1
Walsh, C.A.2
-
16
-
-
1842816486
-
Drosophila myc regulates organ size by inducing cell competition
-
DOI 10.1016/S0092-8674(04)00214-4, PII S0092867404002144
-
C. de la Cova, M. Abril, P. Bellosta, P. Gallant, and L.A. Johnston Drosophila myc regulates organ size by inducing cell competition Cell 117 2004 107 116 (Pubitemid 38469902)
-
(2004)
Cell
, vol.117
, Issue.1
, pp. 107-116
-
-
De La Cova, C.1
Abril, M.2
Bellosta, P.3
Gallant, P.4
Johnston, L.A.5
-
17
-
-
0034013279
-
Primary renal hypoplasia in humans and mice with PAX2 mutations: Evidence of increased apoptosis in fetal kidneys of Pax2(1Neu) +/- mutant mice
-
S. Porteous, E. Torban, N.P. Cho, H. Cunliffe, L. Chua, L. McNoe, T. Ward, C. Souza, P. Gus, and R. Giugliani Primary renal hypoplasia in humans and mice with PAX2 mutations: evidence of increased apoptosis in fetal kidneys of Pax2(1Neu) +/- mutant mice Hum. Mol. Genet. 9 2000 1 11 (Pubitemid 30145283)
-
(2000)
Human Molecular Genetics
, vol.9
, Issue.1
, pp. 1-11
-
-
Porteous, S.1
Torban, E.2
Nam-Pyo, C.3
Cunliffe, H.4
Chua, L.5
McNoe, L.6
Ward, T.7
Souza, C.8
Patricia, G.9
Giugliani, R.10
Sato, T.11
Kankatsu, Y.12
Favor, J.13
Sicotte, M.14
Goodyer, P.15
Eccles, M.16
-
18
-
-
0031819408
-
Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development
-
G. Halder, P. Callaerts, S. Flister, U. Walldorf, U. Kloter, and W.J. Gehring Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development Development 125 1998 2181 2191 (Pubitemid 28336380)
-
(1998)
Development
, vol.125
, Issue.12
, pp. 2181-2191
-
-
Halder, G.1
Callaerts, P.2
Flister, S.3
Walldorf, U.4
Kloter, U.5
Gehring, W.J.6
-
19
-
-
0037094096
-
Kip1 and Bim in response to IL-2
-
M. Stahl, P.F. Dijkers, G.J. Kops, S.M. Lens, P.J. Coffer, B.M. Burgering, and R.H. Medema The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2 J. Immunol. 168 2002 5024 5031 (Pubitemid 34495965)
-
(2002)
Journal of Immunology
, vol.168
, Issue.10
, pp. 5024-5031
-
-
Stahl, M.1
Dijkers, P.F.2
Kops, G.J.P.L.3
Lens, S.M.A.4
Coffer, P.J.5
Burgering, B.M.T.6
Medema, R.H.7
-
20
-
-
0027944004
-
Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia
-
DOI 10.1016/0896-6273(94)90266-6
-
J.C. Martinou, M. Dubois-Dauphin, J.K. Staple, I. Rodriguez, H. Frankowski, M. Missotten, P. Albertini, D. Talabot, S. Catsicas, and C. Pietra Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia Neuron 13 1994 1017 1030 (Pubitemid 24347313)
-
(1994)
Neuron
, vol.13
, Issue.4
, pp. 1017-1030
-
-
Martinou, J.-C.1
Dubois-Dauphin, M.2
Staple, J.K.3
Rodriguez, I.4
Frankowski, H.5
Missotten, M.6
Albertini, P.7
Talabot, D.8
Catsicas, S.9
Pietra, C.10
Huarte, J.11
-
21
-
-
0032493910
-
Reduced apoptosis and cytochrome C-mediated caspase activation in mice lacking Caspase 9
-
DOI 10.1016/S0092-8674(00)81476-2
-
K. Kuida, T.F. Haydar, C.Y. Kuan, Y. Gu, C. Taya, H. Karasuyama, M.S. Su, P. Rakic, and R.A. Flavell Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9 Cell 94 1998 325 337 (Pubitemid 28376077)
-
(1998)
Cell
, vol.94
, Issue.3
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.-Y.3
Gu, Y.4
Taya, C.5
Karasuyama, H.6
Su, M.S.-S.7
Rakic, P.8
Flavell, R.A.9
-
22
-
-
0029925957
-
Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys
-
L.A. Godley, J.B. Kopp, M. Eckhaus, J.J. Paglino, J. Owens, and H.E. Varmus Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys Genes Dev. 10 1996 836 850
-
(1996)
Genes Dev.
, vol.10
, pp. 836-850
-
-
Godley, L.A.1
Kopp, J.B.2
Eckhaus, M.3
Paglino, J.J.4
Owens, J.5
Varmus, H.E.6
-
23
-
-
0019735708
-
Differential mitotic rates and patterns of growth in compartments in the Drosophila wing
-
P. Simpson, and G. Morata Differential mitotic rates and patterns of growth in compartments in the Drosophila wing Dev. Biol. 85 1981 299 308 (Pubitemid 13142508)
-
(1981)
Developmental Biology
, vol.85
, Issue.2
, pp. 299-308
-
-
Simpson, P.1
Morata, G.2
-
24
-
-
78049433049
-
DMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells
-
pii: e1001140
-
M. Ziosi, L.A. Baena-Lopez, D. Grifoni, F. Froldi, A. Pession, F. Garoia, V. Trotta, P. Bellosta, S. Cavicchi, and A. Pession dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells PLoS Genet. 6 2010 pii: e1001140
-
(2010)
PLoS Genet.
, vol.6
-
-
Ziosi, M.1
Baena-Lopez, L.A.2
Grifoni, D.3
Froldi, F.4
Pession, A.5
Garoia, F.6
Trotta, V.7
Bellosta, P.8
Cavicchi, S.9
Pession, A.10
-
25
-
-
77957881882
-
Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap
-
R.M. Neto-Silva, S. de Beco, and L.A. Johnston Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap Dev. Cell 19 2010 507 520
-
(2010)
Dev. Cell
, vol.19
, pp. 507-520
-
-
Neto-Silva, R.M.1
De Beco, S.2
Johnston, L.A.3
-
26
-
-
0032843917
-
Drosophila S6 kinase: A regulator of cell size
-
DOI 10.1126/science.285.5436.2126
-
J. Montagne, M.J. Stewart, H. Stocker, E. Hafen, S.C. Kozma, and G. Thomas Drosophila S6 kinase: a regulator of cell size Science 285 1999 2126 2129 (Pubitemid 29451430)
-
(1999)
Science
, vol.285
, Issue.5436
, pp. 2126-2129
-
-
Montagne, J.1
Stewart, M.J.2
Stocker, H.3
Hafen, E.4
Kozma, S.C.5
Thomas, G.6
-
27
-
-
0034312315
-
Regulation of cellular growth by the Drosophila target of rapamycin dTOR
-
DOI 10.1101/gad.835000
-
H. Zhang, J.P. Stallock, J.C. Ng, C. Reinhard, and T.P. Neufeld Regulation of cellular growth by the Drosophila target of rapamycin dTOR Genes Dev. 14 2000 2712 2724 (Pubitemid 32531198)
-
(2000)
Genes and Development
, vol.14
, Issue.21
, pp. 2712-2724
-
-
Zhang, H.1
Stallock, J.P.2
Ng, J.C.3
Reinhard, C.4
Neufeld, T.P.5
-
28
-
-
0033578793
-
Drosophila myc regulates cellular growth during development
-
DOI 10.1016/S0092-8674(00)81512-3
-
L.A. Johnston, D.A. Prober, B.A. Edgar, R.N. Eisenman, and P. Gallant Drosophila myc regulates cellular growth during development Cell 98 1999 779 790 (Pubitemid 29446895)
-
(1999)
Cell
, vol.98
, Issue.6
, pp. 779-790
-
-
Johnston, L.A.1
Prober, D.A.2
Edgar, B.A.3
Eisenman, R.N.4
Gallant, P.5
-
29
-
-
0033551378
-
The role of c-myc in cellular growth control
-
DOI 10.1038/sj.onc.1202751
-
E.V. Schmidt The role of c-myc in cellular growth control Oncogene 18 1999 2988 2996 (Pubitemid 29276538)
-
(1999)
Oncogene
, vol.18
, Issue.19
, pp. 2988-2996
-
-
Schmidt, E.V.1
-
30
-
-
17744400301
-
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis
-
DOI 10.1093/emboj/20.6.1383
-
K. Boon, H.N. Caron, R. van Asperen, L. Valentijn, M.C. Hermus, P. van Sluis, I. Roobeek, I. Weis, P.A. Voute, and M. Schwab N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis EMBO J. 20 2001 1383 1393 (Pubitemid 32233978)
-
(2001)
EMBO Journal
, vol.20
, Issue.6
, pp. 1383-1393
-
-
Boon, K.1
Caron, H.N.2
Van Asperen, R.3
Valentijn, L.4
Hermus, M.-C.5
Van Sluis, P.6
Roobeek, I.7
Weis, I.8
Voute, P.A.9
Schwab, M.10
Versteeg, R.11
-
31
-
-
0034633761
-
Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo
-
S. Kim, Q. Li, C.V. Dang, and L.A. Lee Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo Proc. Natl. Acad. Sci. USA 97 2000 11198 11202
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11198-11202
-
-
Kim, S.1
Li, Q.2
Dang, C.V.3
Lee, L.A.4
-
32
-
-
0033593316
-
Size control in animal development
-
DOI 10.1016/S0092-8674(00)80563-2
-
I. Conlon, and M. Raff Size control in animal development Cell 96 1999 235 244 (Pubitemid 29059353)
-
(1999)
Cell
, vol.96
, Issue.2
, pp. 235-244
-
-
Conlon, I.1
Raff, M.2
-
33
-
-
0033603208
-
Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4
-
DOI 10.1016/S0092-8674(00)80799-0
-
R. Bohni, J. Riesgo-Escovar, S. Oldham, W. Brogiolo, H. Stocker, B.F. Andruss, K. Beckingham, and E. Hafen Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4 Cell 97 1999 865 875 (Pubitemid 29375046)
-
(1999)
Cell
, vol.97
, Issue.7
, pp. 865-875
-
-
Bohni, R.1
Riesgo-Escovar, J.2
Oldham, S.3
Brogiolo, W.4
Stocker, H.5
Andruss, B.F.6
Beckingham, K.7
Hafen, E.8
-
34
-
-
0033598201
-
Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor
-
DOI 10.1016/S0960-9822(99)80450-3
-
D. Weinkove, T.P. Neufeld, T. Twardzik, M.D. Waterfield, and S.J. Leevers Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor Curr. Biol. 9 1999 1019 1029 (Pubitemid 29456170)
-
(1999)
Current Biology
, vol.9
, Issue.18
, pp. 1019-1029
-
-
Weinkove, D.1
Neufeld, T.P.2
Twardzik, T.3
Waterfield, M.D.4
Leevers, S.J.5
-
35
-
-
0031010050
-
Regulation of skeletal muscle mass in mice by a new TGF-β superfamily member
-
A.C. McPherron, A.M. Lawler, and S.J. Lee Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member Nature 387 1997 83 90 (Pubitemid 27202654)
-
(1997)
Nature
, vol.387
, Issue.6628
, pp. 83-90
-
-
McPherron, A.C.1
Lawler, A.M.2
Lee, S.-J.3
-
36
-
-
0028902594
-
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
-
R.W. Justice, O. Zilian, D.F. Woods, M. Noll, and P.J. Bryant The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation Genes Dev. 9 1995 534 546
-
(1995)
Genes Dev.
, vol.9
, pp. 534-546
-
-
Justice, R.W.1
Zilian, O.2
Woods, D.F.3
Noll, M.4
Bryant, P.J.5
-
37
-
-
0028929414
-
Identifying tumor suppressors in genetic mosaics: The Drosophila lats gene encodes a putative protein kinase
-
T. Xu, W. Wang, S. Zhang, R.A. Stewart, and W. Yu Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase Development 121 1995 1053 1063
-
(1995)
Development
, vol.121
, pp. 1053-1063
-
-
Xu, T.1
Wang, W.2
Zhang, S.3
Stewart, R.A.4
Yu, W.5
-
38
-
-
0036926950
-
Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila
-
DOI 10.1242/dev.00168
-
M. Kango-Singh, R. Nolo, C. Tao, P. Verstreken, P.R. Hiesinger, H.J. Bellen, and G. Halder Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila Development 129 2002 5719 5730 (Pubitemid 36054615)
-
(2002)
Development
, vol.129
, Issue.24
, pp. 5719-5730
-
-
Kango-Singh, M.1
Nolo, R.2
Tao, C.3
Verstreken, P.4
Hiesinger, P.R.5
Bellen, H.J.6
Halder, G.7
-
39
-
-
0037162714
-
Salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
-
DOI 10.1016/S0092-8674(02)00824-3
-
N. Tapon, K.F. Harvey, D.W. Bell, D.C. Wahrer, T.A. Schiripo, D.A. Haber, and I.K. Hariharan salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines Cell 110 2002 467 478 (Pubitemid 35232290)
-
(2002)
Cell
, vol.110
, Issue.4
, pp. 467-478
-
-
Tapon, N.1
Harvey, K.F.2
Bell, D.W.3
Wahrer, D.C.R.4
Schiripo, T.A.5
Haber, D.A.6
Hariharan, I.K.7
-
40
-
-
0042232429
-
Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
-
DOI 10.1016/S0092-8674(03)00549-X
-
S. Wu, J. Huang, J. Dong, and D. Pan hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts Cell 114 2003 445 456 (Pubitemid 37100993)
-
(2003)
Cell
, vol.114
, Issue.4
, pp. 445-456
-
-
Wu, S.1
Huang, J.2
Dong, J.3
Pan, D.4
-
41
-
-
14844297327
-
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats
-
DOI 10.1016/j.cell.2004.12.036
-
Z.C. Lai, X. Wei, T. Shimizu, E. Ramos, M. Rohrbaugh, N. Nikolaidis, L.L. Ho, and Y. Li Control of cell proliferation and apoptosis by mob as tumor suppressor, mats Cell 120 2005 675 685 (Pubitemid 40343079)
-
(2005)
Cell
, vol.120
, Issue.5
, pp. 675-685
-
-
Lai, Z.-C.1
Wei, X.2
Shimizu, T.3
Ramos, E.4
Rohrbaugh, M.5
Nikolaidis, N.6
Ho, L.-L.7
Li, Y.8
-
42
-
-
34247182696
-
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
-
DOI 10.1038/sj.emboj.7601630, PII 7601630
-
X. Wei, T. Shimizu, and Z.C. Lai Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila EMBO J. 26 2007 1772 1781 (Pubitemid 46624045)
-
(2007)
EMBO Journal
, vol.26
, Issue.7
, pp. 1772-1781
-
-
Wei, X.1
Shimizu, T.2
Lai, Z.-C.3
-
43
-
-
23744458034
-
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP
-
DOI 10.1016/j.cell.2005.06.007, PII S0092867405005520
-
J. Huang, S. Wu, J. Barrera, K. Matthews, and D. Pan The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP Cell 122 2005 421 434 (Pubitemid 41127143)
-
(2005)
Cell
, vol.122
, Issue.3
, pp. 421-434
-
-
Huang, J.1
Wu, S.2
Barrera, J.3
Matthews, K.4
Pan, D.5
-
44
-
-
34548636132
-
Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals
-
DOI 10.1016/j.cell.2007.07.019, PII S0092867407009567
-
J. Dong, G. Feldmann, J. Huang, S. Wu, N. Zhang, S.A. Comerford, M.F. Gayyed, R.A. Anders, A. Maitra, and D. Pan Elucidation of a universal size-control mechanism in Drosophila and mammals Cell 130 2007 1120 1133 (Pubitemid 47410268)
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1120-1133
-
-
Dong, J.1
Feldmann, G.2
Huang, J.3
Wu, S.4
Zhang, N.5
Comerford, S.A.6
Gayyed, MarianaF.7
Anders, R.A.8
Maitra, A.9
Pan, D.10
-
45
-
-
77951837150
-
The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version
-
B. Zhao, L. Li, Q. Lei, and K.L. Guan The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version Genes Dev. 24 2010 862 874
-
(2010)
Genes Dev.
, vol.24
, pp. 862-874
-
-
Zhao, B.1
Li, L.2
Lei, Q.3
Guan, K.L.4
-
46
-
-
36549074631
-
YAP1 Increases Organ Size and Expands Undifferentiated Progenitor Cells
-
DOI 10.1016/j.cub.2007.10.039, PII S0960982207021367
-
F.D. Camargo, S. Gokhale, J.B. Johnnidis, D. Fu, G.W. Bell, R. Jaenisch, and T.R. Brummelkamp YAP1 increases organ size and expands undifferentiated progenitor cells Curr. Biol. 17 2007 2054 2060 (Pubitemid 350180465)
-
(2007)
Current Biology
, vol.17
, Issue.23
, pp. 2054-2060
-
-
Camargo, F.D.1
Gokhale, S.2
Johnnidis, J.B.3
Fu, D.4
Bell, G.W.5
Jaenisch, R.6
Brummelkamp, T.R.7
-
47
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
DOI 10.1101/gad.1602907
-
B. Zhao, X. Wei, W. Li, R.S. Udan, Q. Yang, J. Kim, J. Xie, T. Ikenoue, J. Yu, and L. Li Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control Genes Dev. 21 2007 2747 2761 (Pubitemid 350070721)
-
(2007)
Genes and Development
, vol.21
, Issue.21
, pp. 2747-2761
-
-
Zhao, B.1
Wei, X.2
Li, W.3
Udan, R.S.4
Yang, Q.5
Kim, J.6
Xie, J.7
Ikenoue, T.8
Yu, J.9
Li, L.10
Zheng, P.11
Ye, K.12
Chinnaiyan, A.13
Halder, G.14
Lai, Z.-C.15
Guan, K.-L.16
-
48
-
-
70350502865
-
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
-
D. Zhou, C. Conrad, F. Xia, J.S. Park, B. Payer, Y. Yin, G.Y. Lauwers, W. Thasler, J.T. Lee, and J. Avruch Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene Cancer Cell 16 2009 425 438
-
(2009)
Cancer Cell
, vol.16
, pp. 425-438
-
-
Zhou, D.1
Conrad, C.2
Xia, F.3
Park, J.S.4
Payer, B.5
Yin, Y.6
Lauwers, G.Y.7
Thasler, W.8
Lee, J.T.9
Avruch, J.10
-
49
-
-
76249109900
-
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
-
J. Yu, Y. Zheng, J. Dong, S. Klusza, W.M. Deng, and D. Pan Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded Dev. Cell 18 2010 288 299
-
(2010)
Dev. Cell
, vol.18
, pp. 288-299
-
-
Yu, J.1
Zheng, Y.2
Dong, J.3
Klusza, S.4
Deng, W.M.5
Pan, D.6
-
50
-
-
30344445706
-
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
-
DOI 10.1038/ncb1339, PII N1339
-
F. Hamaratoglu, M. Willecke, M. Kango-Singh, R. Nolo, E. Hyun, C. Tao, H. Jafar-Nejad, and G. Halder The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis Nat. Cell Biol. 8 2006 27 36 (Pubitemid 43064794)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.1
, pp. 27-36
-
-
Hamaratoglu, F.1
Willecke, M.2
Kango-Singh, M.3
Nolo, R.4
Hyun, E.5
Tao, C.6
Jafar-Nejad, H.7
Halder, G.8
-
51
-
-
33947105009
-
The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling
-
DOI 10.1016/j.ydbio.2006.12.021, PII S0012160606014564
-
B.J. Pellock, E. Buff, K. White, and I.K. Hariharan The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling Dev. Biol. 304 2007 102 115 (Pubitemid 46399676)
-
(2007)
Developmental Biology
, vol.304
, Issue.1
, pp. 102-115
-
-
Pellock, B.J.1
Buff, E.2
White, K.3
Hariharan, I.K.4
-
52
-
-
25844447107
-
Membrane organization and tumorigenesis - The NF2 tumor suppressor, Merlin
-
DOI 10.1101/gad.1335605
-
A.I. McClatchey, and M. Giovannini Membrane organization and tumorigenesis-the NF2 tumor suppressor, Merlin Genes Dev. 19 2005 2265 2277 (Pubitemid 41396902)
-
(2005)
Genes and Development
, vol.19
, Issue.19
, pp. 2265-2277
-
-
McClatchey, A.I.1
Giovannini, M.2
-
53
-
-
34247609343
-
Shedding light on Merlin's wizardry
-
DOI 10.1016/j.tcb.2007.03.006, PII S0962892407000839
-
T. Okada, L. You, and F.G. Giancotti Shedding light on Merlin's wizardry Trends Cell Biol. 17 2007 222 229 (Pubitemid 46679247)
-
(2007)
Trends in Cell Biology
, vol.17
, Issue.5
, pp. 222-229
-
-
Okada, T.1
You, L.2
Giancotti, F.G.3
-
54
-
-
77954945373
-
The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals
-
N. Zhang, H. Bai, K.K. David, J. Dong, Y. Zheng, J. Cai, M. Giovannini, P. Liu, R.A. Anders, and D. Pan The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals Dev. Cell 19 2010 27 38
-
(2010)
Dev. Cell
, vol.19
, pp. 27-38
-
-
Zhang, N.1
Bai, H.2
David, K.K.3
Dong, J.4
Zheng, Y.5
Cai, J.6
Giovannini, M.7
Liu, P.8
Anders, R.A.9
Pan, D.10
-
55
-
-
76249125346
-
The WW domain protein Kibra acts upstream of Hippo in Drosophila
-
R. Baumgartner, I. Poernbacher, N. Buser, E. Hafen, and H. Stocker The WW domain protein Kibra acts upstream of Hippo in Drosophila Dev. Cell 18 2010 309 316
-
(2010)
Dev. Cell
, vol.18
, pp. 309-316
-
-
Baumgartner, R.1
Poernbacher, I.2
Buser, N.3
Hafen, E.4
Stocker, H.5
-
56
-
-
76249093838
-
Kibra is a regulator of the Salvador/Warts/Hippo signaling network
-
A. Genevet, M.C. Wehr, R. Brain, B.J. Thompson, and N. Tapon Kibra is a regulator of the Salvador/Warts/Hippo signaling network Dev. Cell 18 2010 300 308
-
(2010)
Dev. Cell
, vol.18
, pp. 300-308
-
-
Genevet, A.1
Wehr, M.C.2
Brain, R.3
Thompson, B.J.4
Tapon, N.5
-
57
-
-
61749089153
-
The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie
-
C. Badouel, L. Gardano, N. Amin, A. Garg, R. Rosenfeld, T. Le Bihan, and H. McNeill The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie Dev. Cell 16 2009 411 420
-
(2009)
Dev. Cell
, vol.16
, pp. 411-420
-
-
Badouel, C.1
Gardano, L.2
Amin, N.3
Garg, A.4
Rosenfeld, R.5
Le Bihan, T.6
McNeill, H.7
-
58
-
-
33750611115
-
Fat Cadherin Modulates Organ Size in Drosophila via the Salvador/Warts/Hippo Signaling Pathway
-
DOI 10.1016/j.cub.2006.09.045, PII S0960982206022779
-
F.C. Bennett, and K.F. Harvey Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway Curr. Biol. 16 2006 2101 2110 (Pubitemid 44692100)
-
(2006)
Current Biology
, vol.16
, Issue.21
, pp. 2101-2110
-
-
Bennett, F.C.1
Harvey, K.F.2
-
59
-
-
33749125438
-
Delineation of a Fat tumor suppressor pathway
-
DOI 10.1038/ng1887, PII NG1887
-
E. Cho, Y. Feng, C. Rauskolb, S. Maitra, R. Fehon, and K.D. Irvine Delineation of a Fat tumor suppressor pathway Nat. Genet. 38 2006 1142 1150 (Pubitemid 44470359)
-
(2006)
Nature Genetics
, vol.38
, Issue.10
, pp. 1142-1150
-
-
Cho, E.1
Feng, Y.2
Rauskolb, C.3
Maitra, S.4
Fehon, R.5
Irvine, K.D.6
-
60
-
-
33750624298
-
The Tumor-Suppressor Gene fat Controls Tissue Growth Upstream of Expandedin the Hippo Signaling Pathway
-
DOI 10.1016/j.cub.2006.09.004, PII S0960982206021609
-
E. Silva, Y. Tsatskis, L. Gardano, N. Tapon, and H. McNeill The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway Curr. Biol. 16 2006 2081 2089 (Pubitemid 44692094)
-
(2006)
Current Biology
, vol.16
, Issue.21
, pp. 2081-2089
-
-
Silva, E.1
Tsatskis, Y.2
Gardano, L.3
Tapon, N.4
McNeill, H.5
-
61
-
-
33750614445
-
The Fat Cadherin Acts through the Hippo Tumor-Suppressor Pathway to Regulate Tissue Size
-
DOI 10.1016/j.cub.2006.09.005, PII S0960982206021920
-
M. Willecke, F. Hamaratoglu, M. Kango-Singh, R. Udan, C.L. Chen, C. Tao, X. Zhang, and G. Halder The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size Curr. Biol. 16 2006 2090 2100 (Pubitemid 44692095)
-
(2006)
Current Biology
, vol.16
, Issue.21
, pp. 2090-2100
-
-
Willecke, M.1
Hamaratoglu, F.2
Kango-Singh, M.3
Udan, R.4
Chen, C.-l.5
Tao, C.6
Zhang, X.7
Halder, G.8
-
62
-
-
34247134640
-
Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways
-
DOI 10.1016/j.ydbio.2007.02.004, PII S0012160607001005
-
D.M. Tyler, and N.E. Baker Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways Dev. Biol. 305 2007 187 201 (Pubitemid 46589414)
-
(2007)
Developmental Biology
, vol.305
, Issue.1
, pp. 187-201
-
-
Tyler, D.M.1
Baker, N.E.2
-
63
-
-
33745899356
-
Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins
-
DOI 10.1242/dev.02401
-
H. Matakatsu, and S.S. Blair Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins Development 133 2006 2315 2324 (Pubitemid 44044553)
-
(2006)
Development
, vol.133
, Issue.12
, pp. 2315-2324
-
-
Matakatsu, H.1
Blair, S.S.2
-
64
-
-
77957676987
-
The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila
-
C.L. Chen, K.M. Gajewski, F. Hamaratoglu, W. Bossuyt, L. Sansores-Garcia, C. Tao, and G. Halder The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila Proc. Natl. Acad. Sci. USA 107 2010 15810 15815
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 15810-15815
-
-
Chen, C.L.1
Gajewski, K.M.2
Hamaratoglu, F.3
Bossuyt, W.4
Sansores-Garcia, L.5
Tao, C.6
Halder, G.7
-
65
-
-
77950485564
-
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms
-
N.A. Grzeschik, L.M. Parsons, M.L. Allott, K.F. Harvey, and H.E. Richardson Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms Curr. Biol. 20 2010 573 581
-
(2010)
Curr. Biol.
, vol.20
, pp. 573-581
-
-
Grzeschik, N.A.1
Parsons, L.M.2
Allott, M.L.3
Harvey, K.F.4
Richardson, H.E.5
-
66
-
-
77953738883
-
The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
-
C. Ling, Y. Zheng, F. Yin, J. Yu, J. Huang, Y. Hong, S. Wu, and D. Pan The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded Proc. Natl. Acad. Sci. USA 107 2010 10532 10537
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 10532-10537
-
-
Ling, C.1
Zheng, Y.2
Yin, F.3
Yu, J.4
Huang, J.5
Hong, Y.6
Wu, S.7
Pan, D.8
-
67
-
-
77950478873
-
Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded
-
B.S. Robinson, J. Huang, Y. Hong, and K.H. Moberg Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded Curr. Biol. 20 2010 582 590
-
(2010)
Curr. Biol.
, vol.20
, pp. 582-590
-
-
Robinson, B.S.1
Huang, J.2
Hong, Y.3
Moberg, K.H.4
-
68
-
-
80755129129
-
The sterile 20-like kinase Tao-1 controls tissue growth by regulating the Salvador-Warts-Hippo pathway
-
C.L. Poon, J.I. Lin, X. Zhang, and K.F. Harvey The sterile 20-like kinase Tao-1 controls tissue growth by regulating the Salvador-Warts-Hippo pathway Dev. Cell 21 2011 896 906
-
(2011)
Dev. Cell
, vol.21
, pp. 896-906
-
-
Poon, C.L.1
Lin, J.I.2
Zhang, X.3
Harvey, K.F.4
-
69
-
-
80755136770
-
Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway
-
J.C. Boggiano, P.J. Vanderzalm, and R.G. Fehon Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway Dev. Cell 21 2011 888 895
-
(2011)
Dev. Cell
, vol.21
, pp. 888-895
-
-
Boggiano, J.C.1
Vanderzalm, P.J.2
Fehon, R.G.3
-
70
-
-
79957462240
-
Alpha-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1
-
M.R. Silvis, B.T. Kreger, W.H. Lien, O. Klezovitch, G.M. Rudakova, F.D. Camargo, D.M. Lantz, J.T. Seykora, and V. Vasioukhin alpha-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1 Sci. Signal. 4 2011 ra33
-
(2011)
Sci. Signal.
, vol.4
-
-
Silvis, M.R.1
Kreger, B.T.2
Lien, W.H.3
Klezovitch, O.4
Rudakova, G.M.5
Camargo, F.D.6
Lantz, D.M.7
Seykora, J.T.8
Vasioukhin, V.9
-
71
-
-
79952298459
-
Yap1 acts downstream of alpha-catenin to control epidermal proliferation
-
K. Schlegelmilch, M. Mohseni, O. Kirak, J. Pruszak, J.R. Rodriguez, D. Zhou, B.T. Kreger, V. Vasioukhin, J. Avruch, and T.R. Brummelkamp Yap1 acts downstream of alpha-catenin to control epidermal proliferation Cell 144 2011 782 795
-
(2011)
Cell
, vol.144
, pp. 782-795
-
-
Schlegelmilch, K.1
Mohseni, M.2
Kirak, O.3
Pruszak, J.4
Rodriguez, J.R.5
Zhou, D.6
Kreger, B.T.7
Vasioukhin, V.8
Avruch, J.9
Brummelkamp, T.R.10
-
72
-
-
79961087833
-
E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components
-
N.G. Kim, E. Koh, X. Chen, and B.M. Gumbiner E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components Proc. Natl. Acad. Sci. USA 108 2011 11930 11935
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11930-11935
-
-
Kim, N.G.1
Koh, E.2
Chen, X.3
Gumbiner, B.M.4
-
73
-
-
78650895035
-
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
-
B. Zhao, L. Li, Q. Lu, L.H. Wang, C.Y. Liu, Q. Lei, and K.L. Guan Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein Genes Dev. 25 2011 51 63
-
(2011)
Genes Dev.
, vol.25
, pp. 51-63
-
-
Zhao, B.1
Li, L.2
Lu, Q.3
Wang, L.H.4
Liu, C.Y.5
Lei, Q.6
Guan, K.L.7
-
74
-
-
40849086201
-
SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila
-
Y. Goulev, J.D. Fauny, B. Gonzalez-Marti, D. Flagiello, J. Silber, and A. Zider SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila Curr. Biol. 18 2008 435 441
-
(2008)
Curr. Biol.
, vol.18
, pp. 435-441
-
-
Goulev, Y.1
Fauny, J.D.2
Gonzalez-Marti, B.3
Flagiello, D.4
Silber, J.5
Zider, A.6
-
75
-
-
70349624119
-
Transcription factor choice in the Hippo signaling pathway: Homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc
-
H.W. Peng, M. Slattery, and R.S. Mann Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc Genes Dev. 23 2009 2307 2319
-
(2009)
Genes Dev.
, vol.23
, pp. 2307-2319
-
-
Peng, H.W.1
Slattery, M.2
Mann, R.S.3
-
76
-
-
78651421847
-
Cooperative regulation of growth by Yorkie and Mad through bantam
-
H. Oh, and K.D. Irvine Cooperative regulation of growth by Yorkie and Mad through bantam Dev. Cell 20 2011 109 122
-
(2011)
Dev. Cell
, vol.20
, pp. 109-122
-
-
Oh, H.1
Irvine, K.D.2
-
77
-
-
0032568795
-
Coordination of growth and cell division in the Drosophila wing
-
DOI 10.1016/S0092-8674(00)81462-2
-
T.P. Neufeld, A.F. de la Cruz, L.A. Johnston, and B.A. Edgar Coordination of growth and cell division in the Drosophila wing Cell 93 1998 1183 1193 (Pubitemid 28307423)
-
(1998)
Cell
, vol.93
, Issue.7
, pp. 1183-1193
-
-
Neufeld, T.P.1
De La Cruz, A.F.A.2
Johnston, L.A.3
Edgar, B.A.4
-
78
-
-
33749242966
-
The bantam MicroRNA Is a Target of the Hippo Tumor-Suppressor Pathway
-
DOI 10.1016/j.cub.2006.08.057, PII S0960982206021166
-
R. Nolo, C.M. Morrison, C. Tao, X. Zhang, and G. Halder The bantam microRNA is a target of the hippo tumor-suppressor pathway Curr. Biol. 16 2006 1895 1904 (Pubitemid 44486764)
-
(2006)
Current Biology
, vol.16
, Issue.19
, pp. 1895-1904
-
-
Nolo, R.1
Morrison, C.M.2
Tao, C.3
Zhang, X.4
Halder, G.5
-
79
-
-
33747159113
-
The Hippo Pathway Regulates the bantam microRNA to Control Cell Proliferation and Apoptosis in Drosophila
-
DOI 10.1016/j.cell.2006.07.013, PII S0092867406009536
-
B.J. Thompson, and S.M. Cohen The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila Cell 126 2006 767 774 (Pubitemid 44233623)
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 767-774
-
-
Thompson, B.J.1
Cohen, S.M.2
-
80
-
-
47549095853
-
TEAD mediates YAP-dependent gene induction and growth control
-
DOI 10.1101/gad.1664408
-
B. Zhao, X. Ye, J. Yu, L. Li, W. Li, S. Li, J. Yu, J.D. Lin, C.Y. Wang, and A.M. Chinnaiyan TEAD mediates YAP-dependent gene induction and growth control Genes Dev. 22 2008 1962 1971 (Pubitemid 352008643)
-
(2008)
Genes and Development
, vol.22
, Issue.14
, pp. 1962-1971
-
-
Zhao, B.1
Ye, X.2
Yu, J.3
Li, L.4
Li, W.5
Li, S.6
Yu, J.7
Lin, J.D.8
Wang, C.-Y.9
Chinnaiyan, A.M.10
Lai, Z.-C.11
Guan, K.-L.12
-
81
-
-
73349128777
-
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
-
J. Zhang, J.Y. Ji, M. Yu, M. Overholtzer, G.A. Smolen, R. Wang, J.S. Brugge, N.J. Dyson, and D.A. Haber YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway Nat. Cell Biol. 11 2009 1444 1450
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1444-1450
-
-
Zhang, J.1
Ji, J.Y.2
Yu, M.3
Overholtzer, M.4
Smolen, G.A.5
Wang, R.6
Brugge, J.S.7
Dyson, N.J.8
Haber, D.A.9
-
82
-
-
31044440368
-
From cell structure to transcription: Hippo Forges a new path
-
DOI 10.1016/j.cell.2006.01.005, PII S0092867406000535
-
B.A. Edgar From cell structure to transcription: Hippo forges a new path Cell 124 2006 267 273 (Pubitemid 43121976)
-
(2006)
Cell
, vol.124
, Issue.2
, pp. 267-273
-
-
Edgar, B.A.1
-
83
-
-
34247191134
-
Hippo signaling in organ size control
-
DOI 10.1101/gad.1536007
-
D. Pan Hippo signaling in organ size control Genes Dev 21 2007 886 897 (Pubitemid 46625638)
-
(2007)
Genes and Development
, vol.21
, Issue.8
, pp. 886-897
-
-
Pan, D.1
-
85
-
-
0042733354
-
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
-
DOI 10.1016/S0092-8674(03)00557-9
-
K.F. Harvey, C.M. Pfleger, and I.K. Hariharan The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis Cell 114 2003 457 467 (Pubitemid 37100994)
-
(2003)
Cell
, vol.114
, Issue.4
, pp. 457-467
-
-
Harvey, K.F.1
Pfleger, C.M.2
Hariharan, I.K.3
-
86
-
-
0142123293
-
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
-
DOI 10.1101/gad.1134003
-
J. Jia, W. Zhang, B. Wang, R. Trinko, and J. Jiang The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis Genes Dev. 17 2003 2514 2519 (Pubitemid 37271421)
-
(2003)
Genes and Development
, vol.17
, Issue.20
, pp. 2514-2519
-
-
Jia, J.1
Zhang, W.2
Wang, B.3
Trinko, R.4
Jiang, J.5
-
87
-
-
77955868800
-
Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver
-
S. Benhamouche, M. Curto, I. Saotome, A.B. Gladden, C.H. Liu, M. Giovannini, and A.I. McClatchey Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver Genes Dev. 24 2010 1718 1730
-
(2010)
Genes Dev.
, vol.24
, pp. 1718-1730
-
-
Benhamouche, S.1
Curto, M.2
Saotome, I.3
Gladden, A.B.4
Liu, C.H.5
Giovannini, M.6
McClatchey, A.I.7
-
88
-
-
76549124517
-
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver
-
L. Lu, Y. Li, S.M. Kim, W. Bossuyt, P. Liu, Q. Qiu, Y. Wang, G. Halder, M.J. Finegold, and J.S. Lee Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver Proc. Natl. Acad. Sci. USA 107 2010 1437 1442
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 1437-1442
-
-
Lu, L.1
Li, Y.2
Kim, S.M.3
Bossuyt, W.4
Liu, P.5
Qiu, Q.6
Wang, Y.7
Halder, G.8
Finegold, M.J.9
Lee, J.S.10
-
89
-
-
76549127712
-
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression
-
H. Song, K.K. Mak, L. Topol, K. Yun, J. Hu, L. Garrett, Y. Chen, O. Park, J. Chang, and R.M. Simpson Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression Proc. Natl. Acad. Sci. USA 107 2010 1431 1436
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 1431-1436
-
-
Song, H.1
Mak, K.K.2
Topol, L.3
Yun, K.4
Hu, J.5
Garrett, L.6
Chen, Y.7
Park, O.8
Chang, J.9
Simpson, R.M.10
-
90
-
-
78650187792
-
The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration
-
R.L. Shaw, A. Kohlmaier, C. Polesello, C. Veelken, B.A. Edgar, and N. Tapon The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration Development 137 2010 4147 4158
-
(2010)
Development
, vol.137
, pp. 4147-4158
-
-
Shaw, R.L.1
Kohlmaier, A.2
Polesello, C.3
Veelken, C.4
Edgar, B.A.5
Tapon, N.6
-
91
-
-
77953040994
-
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation
-
I. Lian, J. Kim, H. Okazawa, J. Zhao, B. Zhao, J. Yu, A. Chinnaiyan, M.A. Israel, L.S. Goldstein, and R. Abujarour The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation Genes Dev. 24 2010 1106 1118
-
(2010)
Genes Dev.
, vol.24
, pp. 1106-1118
-
-
Lian, I.1
Kim, J.2
Okazawa, H.3
Zhao, J.4
Zhao, B.5
Yu, J.6
Chinnaiyan, A.7
Israel, M.A.8
Goldstein, L.S.9
Abujarour, R.10
-
92
-
-
77952336576
-
The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
-
K.P. Lee, J.H. Lee, T.S. Kim, T.H. Kim, H.D. Park, J.S. Byun, M.C. Kim, W.I. Jeong, D.F. Calvisi, and J.M. Kim The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis Proc. Natl. Acad. Sci. USA 107 2010 8248 8253
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 8248-8253
-
-
Lee, K.P.1
Lee, J.H.2
Kim, T.S.3
Kim, T.H.4
Park, H.D.5
Byun, J.S.6
Kim, M.C.7
Jeong, W.I.8
Calvisi, D.F.9
Kim, J.M.10
-
93
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
M. Cordenonsi, F. Zanconato, L. Azzolin, M. Forcato, A. Rosato, C. Frasson, M. Inui, M. Montagner, A.R. Parenti, and A. Poletti The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells Cell 147 2011 759 772
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
Forcato, M.4
Rosato, A.5
Frasson, C.6
Inui, M.7
Montagner, M.8
Parenti, A.R.9
Poletti, A.10
-
94
-
-
0025776523
-
Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast
-
J. Heitman, N.R. Movva, and M.N. Hall Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast Science 253 1991 905 909 (Pubitemid 21917235)
-
(1991)
Science
, vol.253
, Issue.5022
, pp. 905-909
-
-
Hietman, J.1
Movva, N.R.2
Hall, M.N.3
-
95
-
-
0027311858
-
1 progression
-
DOI 10.1016/0092-8674(93)90144-F
-
J. Kunz, R. Henriquez, U. Schneider, M. Deuter-Reinhard, N.R. Movva, and M.N. Hall Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression Cell 73 1993 585 596 (Pubitemid 23143356)
-
(1993)
Cell
, vol.73
, Issue.3
, pp. 585-596
-
-
Kunz, J.1
Henriquez, R.2
Schneider, U.3
Deuter-Reinhard, M.4
Movva, N.R.5
Hall, M.N.6
-
96
-
-
0029842109
-
Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP
-
J. Choi, J. Chen, S.L. Schreiber, and J. Clardy Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP Science 273 1996 239 242 (Pubitemid 26285890)
-
(1996)
Science
, vol.273
, Issue.5272
, pp. 239-242
-
-
Choi, J.1
Chen, J.2
Schreiber, S.L.3
Clardy, J.4
-
97
-
-
0030663735
-
Role of the tuberous sclerosis gene-2 product in cell cycle control. Loss of the tuberous sclerosis gene-2 induces quiescent cells to enter S phase
-
DOI 10.1074/jbc.272.46.29301
-
T. Soucek, O. Pusch, R. Wienecke, J.E. DeClue, and M. Hengstschlager Role of the tuberous sclerosis gene-2 product in cell cycle control. Loss of the tuberous sclerosis gene-2 induces quiescent cells to enter S phase J. Biol. Chem. 272 1997 29301 29308 (Pubitemid 27498223)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.46
, pp. 29301-29308
-
-
Soucek, T.1
Pusch, O.2
Wienecke, R.3
DeClue, J.E.4
Hengstschlager, M.5
-
98
-
-
0035833356
-
Tuberous sclerosis causing mutants of the TSC2 gene product affect proliferation and p27 expression
-
DOI 10.1038/sj.onc.1204627
-
T. Soucek, M. Rosner, A. Miloloza, M. Kubista, J.P. Cheadle, J.R. Sampson, and M. Hengstschlager Tuberous sclerosis causing mutants of the TSC2 gene product affect proliferation and p27 expression Oncogene 20 2001 4904 4909 (Pubitemid 32803162)
-
(2001)
Oncogene
, vol.20
, Issue.35
, pp. 4904-4909
-
-
Soucek, T.1
Rosner, M.2
Miloloza, A.3
Kubista, M.4
Cheadle, J.P.5
Sampson, J.R.6
Hengstschlager, M.7
-
99
-
-
0034312279
-
Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin
-
DOI 10.1101/gad.845700
-
S. Oldham, J. Montagne, T. Radimerski, G. Thomas, and E. Hafen Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin Genes Dev. 14 2000 2689 2694 (Pubitemid 32531195)
-
(2000)
Genes and Development
, vol.14
, Issue.21
, pp. 2689-2694
-
-
Oldham, S.1
Montagne, J.2
Radimerski, T.3
Thomas, G.4
Hafen, E.5
-
100
-
-
0036753494
-
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
-
DOI 10.1016/S1097-2765(02)00636-6
-
R. Loewith, E. Jacinto, S. Wullschleger, A. Lorberg, J.L. Crespo, D. Bonenfant, W. Oppliger, P. Jenoe, and M.N. Hall Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control Mol. Cell 10 2002 457 468 (Pubitemid 35284167)
-
(2002)
Molecular Cell
, vol.10
, Issue.3
, pp. 457-468
-
-
Loewith, R.1
Jacinto, E.2
Wullschleger, S.3
Lorberg, A.4
Crespo, J.L.5
Bonenfant, D.6
Oppliger, W.7
Jenoe, P.8
Hall, M.N.9
-
101
-
-
33749406921
-
Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region
-
DOI 10.1074/jbc.M606087200
-
T. Takahara, K. Hara, K. Yonezawa, H. Sorimachi, and T. Maeda Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region J. Biol. Chem. 281 2006 28605 28614 (Pubitemid 44507003)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.39
, pp. 28605-28614
-
-
Takahara, T.1
Hara, K.2
Yonezawa, K.3
Sorimachi, H.4
Maeda, T.5
-
102
-
-
33747690458
-
Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1
-
DOI 10.1074/jbc.M603566200
-
L. Wang, C.J. Rhodes, and J.C. Lawrence Jr. Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1 J. Biol. Chem. 281 2006 24293 24303 (Pubitemid 44274202)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.34
, pp. 24293-24303
-
-
Wang, L.1
Rhodes, C.J.2
Lawrence Jr., J.C.3
-
103
-
-
77953091045
-
Structure of the human mTOR complex i and its implications for rapamycin inhibition
-
C.K. Yip, K. Murata, T. Walz, D.M. Sabatini, and S.A. Kang Structure of the human mTOR complex I and its implications for rapamycin inhibition Mol. Cell 38 2010 768 774
-
(2010)
Mol. Cell
, vol.38
, pp. 768-774
-
-
Yip, C.K.1
Murata, K.2
Walz, T.3
Sabatini, D.M.4
Kang, S.A.5
-
104
-
-
33644781670
-
Drosophila target of rapamycin kinase functions as a multimer
-
DOI 10.1534/genetics.105.051979
-
Y. Zhang, C.J. Billington Jr., D. Pan, and T.P. Neufeld Drosophila target of rapamycin kinase functions as a multimer Genetics 172 2006 355 362 (Pubitemid 43345497)
-
(2006)
Genetics
, vol.172
, Issue.1
, pp. 355-362
-
-
Zhang, Y.1
Billington Jr., C.J.2
Pan, D.3
Neufeld, T.P.4
-
105
-
-
67349241955
-
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival
-
T.R. Peterson, M. Laplante, C.C. Thoreen, Y. Sancak, S.A. Kang, W.M. Kuehl, N.S. Gray, and D.M. Sabatini DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival Cell 137 2009 873 886
-
(2009)
Cell
, vol.137
, pp. 873-886
-
-
Peterson, T.R.1
Laplante, M.2
Thoreen, C.C.3
Sancak, Y.4
Kang, S.A.5
Kuehl, W.M.6
Gray, N.S.7
Sabatini, D.M.8
-
106
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
DOI 10.1016/S0092-8674(02)00833-4
-
K. Hara, Y. Maruki, X. Long, K. Yoshino, N. Oshiro, S. Hidayat, C. Tokunaga, J. Avruch, and K. Yonezawa Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action Cell 110 2002 177 189 (Pubitemid 34876546)
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 177-189
-
-
Hara, K.1
Maruki, Y.2
Long, X.3
Yoshino, K.-I.4
Oshiro, N.5
Hidayat, S.6
Tokunaga, C.7
Avruch, J.8
Yonezawa, K.9
-
107
-
-
0037178786
-
MTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
DOI 10.1016/S0092-8674(02)00808-5
-
D.H. Kim, D.D. Sarbassov, S.M. Ali, J.E. King, R.R. Latek, H. Erdjument-Bromage, P. Tempst, and D.M. Sabatini mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery Cell 110 2002 163 175 (Pubitemid 34876545)
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 163-175
-
-
Kim, D.-H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
108
-
-
33646566510
-
Functional Genomics Identifies TOR-Regulated Genes that Control Growth and Division
-
DOI 10.1016/j.cub.2006.03.084, PII S0960982206014175
-
D.A. Guertin, K.V. Guntur, G.W. Bell, C.C. Thoreen, and D.M. Sabatini Functional genomics identifies TOR-regulated genes that control growth and division Curr. Biol. 16 2006 958 970 (Pubitemid 43728212)
-
(2006)
Current Biology
, vol.16
, Issue.10
, pp. 958-970
-
-
Guertin, D.A.1
Guntur, K.V.P.2
Bell, G.W.3
Thoreen, C.C.4
Sabatini, D.M.5
-
109
-
-
33847397874
-
Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40
-
DOI 10.1038/ncb1547, PII NCB1547
-
E. Vander Haar, S.I. Lee, S. Bandhakavi, T.J. Griffin, and D.H. Kim Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40 Nat. Cell Biol. 9 2007 316 323 (Pubitemid 46344611)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.3
, pp. 316-323
-
-
Haar, E.V.1
Lee, S.2
Bandhakavi, S.3
Griffin, T.J.4
Kim, D.-H.5
-
110
-
-
33947264077
-
PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase
-
DOI 10.1016/j.molcel.2007.03.003, PII S1097276507001487
-
Y. Sancak, C.C. Thoreen, T.R. Peterson, R.A. Lindquist, S.A. Kang, E. Spooner, S.A. Carr, and D.M. Sabatini PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase Mol. Cell 25 2007 903 915 (Pubitemid 46436534)
-
(2007)
Molecular Cell
, vol.25
, Issue.6
, pp. 903-915
-
-
Sancak, Y.1
Thoreen, C.C.2
Peterson, T.R.3
Lindquist, R.A.4
Kang, S.A.5
Spooner, E.6
Carr, S.A.7
Sabatini, D.M.8
-
111
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
DOI 10.1016/j.cub.2004.06.054, PII S0960982204004713
-
D.D. Sarbassov, S.M. Ali, D.H. Kim, D.A. Guertin, R.R. Latek, H. Erdjument-Bromage, P. Tempst, and D.M. Sabatini Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton Curr. Biol. 14 2004 1296 1302 (Pubitemid 38991819)
-
(2004)
Current Biology
, vol.14
, Issue.14
, pp. 1296-1302
-
-
Dos D. Sarbassov1
Ali, S.M.2
Kim, D.-H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
112
-
-
33751079895
-
Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity
-
DOI 10.1101/gad.1461206
-
Q. Yang, K. Inoki, T. Ikenoue, and K.L. Guan Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity Genes Dev. 20 2006 2820 2832 (Pubitemid 44771744)
-
(2006)
Genes and Development
, vol.20
, Issue.20
, pp. 2820-2832
-
-
Yang, Q.1
Inoki, K.2
Ikenoue, T.3
Guan, K.-L.4
-
113
-
-
34347210090
-
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
-
DOI 10.1042/BJ20070540
-
L.R. Pearce, X. Huang, J. Boudeau, R. Pawlowski, S. Wullschleger, M. Deak, A.F. Ibrahim, R. Gourlay, M.A. Magnuson, and D.R. Alessi Identification of Protor as a novel Rictor-binding component of mTOR complex-2 Biochem. J. 405 2007 513 522 (Pubitemid 47172049)
-
(2007)
Biochemical Journal
, vol.405
, Issue.3
, pp. 513-522
-
-
Pearce, L.R.1
Huang, X.2
Boudeau, J.3
Pawlowski, R.4
Wullschleger, S.5
Deak, M.6
Ibrahim, A.F.M.7
Gourlay, R.8
Magnuson, M.A.9
Alessi, D.R.10
-
114
-
-
7944235758
-
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
-
DOI 10.1038/ncb1183
-
E. Jacinto, R. Loewith, A. Schmidt, S. Lin, M.A. Ruegg, A. Hall, and M.N. Hall Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive Nat. Cell Biol. 6 2004 1122 1128 (Pubitemid 39468014)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.11
, pp. 1122-1128
-
-
Jacinto, E.1
Loewith, R.2
Schmidt, A.3
Lin, S.4
Ruegg, M.A.5
Hall, A.6
Hall, M.N.7
-
115
-
-
33749076673
-
SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity
-
DOI 10.1016/j.cell.2006.08.033, PII S0092867406011470
-
E. Jacinto, V. Facchinetti, D. Liu, N. Soto, S. Wei, S.Y. Jung, Q. Huang, J. Qin, and B. Su SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity Cell 127 2006 125 137 (Pubitemid 44466632)
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
Soto, N.4
Wei, S.5
Jung, S.Y.6
Huang, Q.7
Qin, J.8
Su, B.9
-
116
-
-
65249155441
-
An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation
-
Y.Y. Chang, and T.P. Neufeld An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation Mol. Biol. Cell 20 2009 2004 2014
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 2004-2014
-
-
Chang, Y.Y.1
Neufeld, T.P.2
-
117
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
C.H. Jung, C.B. Jun, S.H. Ro, Y.M. Kim, N.M. Otto, J. Cao, M. Kundu, and D.H. Kim ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery Mol. Biol. Cell 20 2009 1992 2003
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
Kim, Y.M.4
Otto, N.M.5
Cao, J.6
Kundu, M.7
Kim, D.H.8
-
118
-
-
75749090429
-
Tor directly controls the Atg1 kinase complex to regulate autophagy
-
Y. Kamada, K. Yoshino, C. Kondo, T. Kawamata, N. Oshiro, K. Yonezawa, and Y. Ohsumi Tor directly controls the Atg1 kinase complex to regulate autophagy Mol. Cell Biol. 30 2010 1049 1058
-
(2010)
Mol. Cell Biol.
, vol.30
, pp. 1049-1058
-
-
Kamada, Y.1
Yoshino, K.2
Kondo, C.3
Kawamata, T.4
Oshiro, N.5
Yonezawa, K.6
Ohsumi, Y.7
-
119
-
-
0036712905
-
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
-
DOI 10.1038/ncb847
-
X. Gao, Y. Zhang, P. Arrazola, O. Hino, T. Kobayashi, R.S. Yeung, B. Ru, and D. Pan Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling Nat. Cell Biol. 4 2002 699 704 (Pubitemid 34993706)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.9
, pp. 699-704
-
-
Gao, X.1
Zhang, Y.2
Arrazola, P.3
Hino, O.4
Kobayashi, T.5
Yeung, R.S.6
Ru, B.7
Pan, D.8
-
120
-
-
0037163033
-
Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation: A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)
-
DOI 10.1074/jbc.M202678200
-
E.A. Goncharova, D.A. Goncharov, A. Eszterhas, D.S. Hunter, M.K. Glassberg, R.S. Yeung, C.L. Walker, D. Noonan, D.J. Kwiatkowski, and M.M. Chou Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM) J. Biol. Chem. 277 2002 30958 30967 (Pubitemid 34970798)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.34
, pp. 30958-30967
-
-
Goncharova, E.A.1
Goncharov, D.A.2
Eszterhas, A.3
Hunter, D.S.4
Glassberg, M.K.5
Yeung, R.S.6
Walker, C.L.7
Noonan, D.8
Kwiatkowski, D.J.9
Chou, M.M.10
Panettieri Jr., R.A.11
Krymskaya, V.P.12
-
121
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
DOI 10.1038/ncb839
-
K. Inoki, Y. Li, T. Zhu, J. Wu, and K.L. Guan TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling Nat. Cell Biol. 4 2002 648 657 (Pubitemid 34993700)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.9
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.-L.5
-
122
-
-
0042701991
-
Tuberous Sclerosis Complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
-
DOI 10.1016/S0960-9822(03)00506-2
-
A.R. Tee, B.D. Manning, P.P. Roux, L.C. Cantley, and J. Blenis Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb Curr. Biol. 13 2003 1259 1268 (Pubitemid 36953298)
-
(2003)
Current Biology
, vol.13
, Issue.15
, pp. 1259-1268
-
-
Tee, A.R.1
Manning, B.D.2
Roux, P.P.3
Cantley, L.C.4
Blenis, J.5
-
123
-
-
0038433304
-
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
-
DOI 10.1016/S1097-2765(03)00220-X
-
A. Garami, F.J. Zwartkruis, T. Nobukuni, M. Joaquin, M. Roccio, H. Stocker, S.C. Kozma, E. Hafen, J.L. Bos, and G. Thomas Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2 Mol. Cell 11 2003 1457 1466 (Pubitemid 36776533)
-
(2003)
Molecular Cell
, vol.11
, Issue.6
, pp. 1457-1466
-
-
Garami, A.1
Zwartkruis, F.J.T.2
Nobukuni, T.3
Joaquin, M.4
Roccio, M.5
Stocker, H.6
Kozma, S.C.7
Hafen, E.8
Bos, J.L.9
Thomas, G.10
-
124
-
-
0043127125
-
Rheb GTpase is a direct target of TSC2 GAP activity and regulates mTOR signaling
-
DOI 10.1101/gad.1110003
-
K. Inoki, Y. Li, T. Xu, and K.L. Guan Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling Genes Dev. 17 2003 1829 1834 (Pubitemid 36944560)
-
(2003)
Genes and Development
, vol.17
, Issue.15
, pp. 1829-1834
-
-
Inoki, K.1
Li, Y.2
Xu, T.3
Guan, K.-L.4
-
125
-
-
0036714127
-
Akt regulates growth by directly phosphorylating Tsc2
-
DOI 10.1038/ncb840
-
C.J. Potter, L.G. Pedraza, and T. Xu Akt regulates growth by directly phosphorylating Tsc2 Nat. Cell Biol. 4 2002 658 665 (Pubitemid 34993701)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.9
, pp. 658-665
-
-
Potter, C.J.1
Pedraza, L.G.2
Xu, T.3
-
126
-
-
0344629443
-
Signaling from Akt to FRAP/TOR Targets both 4E-BP and S6K in Drosophila melanogaster
-
DOI 10.1128/MCB.23.24.9117-9126.2003
-
M. Miron, P. Lasko, and N. Sonenberg Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster Mol. Cell Biol. 23 2003 9117 9126 (Pubitemid 37499801)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.24
, pp. 9117-9126
-
-
Miron, M.1
Lasko, P.2
Sonenberg, N.3
-
127
-
-
48649085816
-
Regulation of TORC1 by Rag GTPases in nutrient response
-
E. Kim, P. Goraksha-Hicks, L. Li, T.P. Neufeld, and K.L. Guan Regulation of TORC1 by Rag GTPases in nutrient response Nat. Cell Biol. 10 2008 935 945
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 935-945
-
-
Kim, E.1
Goraksha-Hicks, P.2
Li, L.3
Neufeld, T.P.4
Guan, K.L.5
-
128
-
-
77951768486
-
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
-
Y. Sancak, L. Bar-Peled, R. Zoncu, A.L. Markhard, S. Nada, and D.M. Sabatini Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids Cell 141 2010 290 303
-
(2010)
Cell
, vol.141
, pp. 290-303
-
-
Sancak, Y.1
Bar-Peled, L.2
Zoncu, R.3
Markhard, A.L.4
Nada, S.5
Sabatini, D.M.6
-
129
-
-
34147141941
-
A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling
-
DOI 10.1042/BJ20061881
-
G.M. Findlay, L. Yan, J. Procter, V. Mieulet, and R.F. Lamb A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling Biochem. J. 403 2007 13 20 (Pubitemid 46569862)
-
(2007)
Biochemical Journal
, vol.403
, Issue.1
, pp. 13-20
-
-
Findlay, G.M.1
Yan, L.2
Procter, J.3
Mieulet, V.4
Lamb, R.F.5
-
130
-
-
77649269312
-
PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR
-
L. Yan, V. Mieulet, D. Burgess, G.M. Findlay, K. Sully, J. Procter, J. Goris, V. Janssens, N.A. Morrice, and R.F. Lamb PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR Mol. Cell 37 2010 633 642
-
(2010)
Mol. Cell
, vol.37
, pp. 633-642
-
-
Yan, L.1
Mieulet, V.2
Burgess, D.3
Findlay, G.M.4
Sully, K.5
Procter, J.6
Goris, J.7
Janssens, V.8
Morrice, N.A.9
Lamb, R.F.10
-
131
-
-
25444457577
-
HVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase
-
DOI 10.1074/jbc.M507201200
-
M.P. Byfield, J.T. Murray, and J.M. Backer hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase J. Biol. Chem. 280 2005 33076 33082 (Pubitemid 41368357)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.38
, pp. 33076-33082
-
-
Byfield, M.P.1
Murray, J.T.2
Backer, J.M.3
-
132
-
-
26444575415
-
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase
-
DOI 10.1073/pnas.0506925102
-
T. Nobukuni, M. Joaquin, M. Roccio, S.G. Dann, S.Y. Kim, P. Gulati, M.P. Byfield, J.M. Backer, F. Natt, and J.L. Bos Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase Proc. Natl. Acad. Sci. USA 102 2005 14238 14243 (Pubitemid 41429682)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.40
, pp. 14238-14243
-
-
Nobukuni, T.1
Joaquin, M.2
Roccio, M.3
Dann, S.G.4
Kim, S.Y.5
Gulati, P.6
Byfield, M.P.7
Backer, J.M.8
Natt, F.9
Bos, J.L.10
Zwartkruis, F.J.T.11
Thomas, G.12
-
133
-
-
44149127993
-
The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila
-
DOI 10.1083/jcb.200712051
-
G. Juhasz, J.H. Hill, Y. Yan, M. Sass, E.H. Baehrecke, J.M. Backer, and T.P. Neufeld The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila J. Cell Biol. 181 2008 655 666 (Pubitemid 351717512)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.4
, pp. 655-666
-
-
Juhasz, G.1
Hill, J.H.2
Yan, Y.3
Sass, M.4
Baehrecke, E.H.5
Backer, J.M.6
Neufeld, T.P.7
-
134
-
-
34648828532
-
AMP-activated/SNF1 protein kinases: Conserved guardians of cellular energy
-
DOI 10.1038/nrm2249, PII NRM2249
-
D.G. Hardie AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy Nat. Rev. Mol. Cell Biol. 8 2007 774 785 (Pubitemid 47462132)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.10
, pp. 774-785
-
-
Hardie, D.G.1
-
135
-
-
0345167800
-
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
-
DOI 10.1016/S0092-8674(03)00929-2
-
K. Inoki, T. Zhu, and K.L. Guan TSC2 mediates cellular energy response to control cell growth and survival Cell 115 2003 577 590 (Pubitemid 37506046)
-
(2003)
Cell
, vol.115
, Issue.5
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
Guan, K.-L.3
-
136
-
-
42949139481
-
AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
-
DOI 10.1016/j.molcel.2008.03.003, PII S109727650800169X
-
D.M. Gwinn, D.B. Shackelford, D.F. Egan, M.M. Mihaylova, A. Mery, D.S. Vasquez, B.E. Turk, and R.J. Shaw AMPK phosphorylation of raptor mediates a metabolic checkpoint Mol. Cell 30 2008 214 226 (Pubitemid 351626684)
-
(2008)
Molecular Cell
, vol.30
, Issue.2
, pp. 214-226
-
-
Gwinn, D.M.1
Shackelford, D.B.2
Egan, D.F.3
Mihaylova, M.M.4
Mery, A.5
Vasquez, D.S.6
Turk, B.E.7
Shaw, R.J.8
-
137
-
-
33748153690
-
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
-
DOI 10.1016/j.cell.2006.06.055, PII S0092867406010166
-
K. Inoki, H. Ouyang, T. Zhu, C. Lindvall, Y. Wang, X. Zhang, Q. Yang, C. Bennett, Y. Harada, and K. Stankunas TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth Cell 126 2006 955 968 (Pubitemid 44310775)
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 955-968
-
-
Inoki, K.1
Ouyang, H.2
Zhu, T.3
Lindvall, C.4
Wang, Y.5
Zhang, X.6
Yang, Q.7
Bennett, C.8
Harada, Y.9
Stankunas, K.10
Wang, C.-y.11
He, X.12
MacDougald, O.A.13
You, M.14
Williams, B.O.15
Guan, K.-L.16
-
138
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated translational control
-
X.M. Ma, and J. Blenis Molecular mechanisms of mTOR-mediated translational control Nat. Rev. Mol. Cell Biol. 10 2009 307 318
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
139
-
-
27744569843
-
MTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
-
DOI 10.1016/j.cell.2005.10.024, PII S0092867405011578
-
M.K. Holz, B.A. Ballif, S.P. Gygi, and J. Blenis mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events Cell 123 2005 569 580 (Pubitemid 41608461)
-
(2005)
Cell
, vol.123
, Issue.4
, pp. 569-580
-
-
Holz, M.K.1
Ballif, B.A.2
Gygi, S.P.3
Blenis, J.4
-
140
-
-
0037097863
-
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
-
DOI 10.1101/gad.995802
-
D.C. Fingar, S. Salama, C. Tsou, E. Harlow, and J. Blenis Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E Genes Dev. 16 2002 1472 1487 (Pubitemid 34686329)
-
(2002)
Genes and Development
, vol.16
, Issue.12
, pp. 1472-1487
-
-
Fingar, D.C.1
Salama, S.2
Tsou, C.3
Harlow, E.4
Blenis, J.5
-
141
-
-
77955287244
-
MTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1
-
T. Kantidakis, B.A. Ramsbottom, J.L. Birch, S.N. Dowding, and R.J. White mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1 Proc. Natl. Acad. Sci. USA 107 2010 11823 11828
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 11823-11828
-
-
Kantidakis, T.1
Ramsbottom, B.A.2
Birch, J.L.3
Dowding, S.N.4
White, R.J.5
-
142
-
-
1542343973
-
MTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability
-
DOI 10.1101/gad.285504
-
C. Mayer, J. Zhao, X. Yuan, and I. Grummt mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability Genes Dev. 18 2004 423 434 (Pubitemid 38316349)
-
(2004)
Genes and Development
, vol.18
, Issue.4
, pp. 423-434
-
-
Mayer, C.1
Zhao, J.2
Yuan, X.3
Grummt, I.4
-
143
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
J. Kim, M. Kundu, B. Viollet, and K.L. Guan AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 Nat. Cell Biol. 13 2011 132 141
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
144
-
-
0037108151
-
Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling
-
T. Radimerski, J. Montagne, M. Hemmings-Mieszczak, and G. Thomas Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling Genes Dev. 16 2002 2627 2632
-
(2002)
Genes Dev.
, vol.16
, pp. 2627-2632
-
-
Radimerski, T.1
Montagne, J.2
Hemmings-Mieszczak, M.3
Thomas, G.4
-
145
-
-
0036119219
-
DS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1
-
DOI 10.1038/ncb763
-
T. Radimerski, J. Montagne, F. Rintelen, H. Stocker, J. van der Kaay, C.P. Downes, E. Hafen, and G. Thomas dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1 Nat. Cell Biol. 4 2002 251 255 (Pubitemid 34218200)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.3
, pp. 251-255
-
-
Radimerski, T.1
Montagne, J.2
Rintelen, F.3
Stocker, H.4
Van Der Kaay, J.5
Downes, C.P.6
Hafen, E.7
Thomas, G.8
-
146
-
-
0141733277
-
A nutrient sensor mechanism controls Drosophila growth
-
DOI 10.1016/S0092-8674(03)00713-X
-
J. Colombani, S. Raisin, S. Pantalacci, T. Radimerski, J. Montagne, and P. Leopold A nutrient sensor mechanism controls Drosophila growth Cell 114 2003 739 749 (Pubitemid 37186768)
-
(2003)
Cell
, vol.114
, Issue.6
, pp. 739-749
-
-
Colombani, J.1
Raisin, S.2
Pantalacci, S.3
Radimerski, T.4
Montagne, J.5
Leopold, P.6
-
147
-
-
0035805180
-
The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation
-
DOI 10.1016/S0092-8674(01)00332-4
-
N. Tapon, N. Ito, B.J. Dickson, J.E. Treisman, and I.K. Hariharan The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation Cell 105 2001 345 355 (Pubitemid 32455341)
-
(2001)
Cell
, vol.105
, Issue.3
, pp. 345-355
-
-
Tapon, N.1
Ito, N.2
Dickson, B.J.3
Treisman, J.E.4
Hariharan, I.K.5
-
148
-
-
0041827366
-
Drosophila Rheb GTPase is required for cell cycle progression and cell growth
-
DOI 10.1242/jcs.00661
-
P.H. Patel, N. Thapar, L. Guo, M. Martinez, J. Maris, C.L. Gau, J.A. Lengyel, and F. Tamanoi Drosophila Rheb GTPase is required for cell cycle progression and cell growth J. Cell Sci. 116 2003 3601 3610 (Pubitemid 37063403)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.17
, pp. 3601-3610
-
-
Patel, P.H.1
Thapar, N.2
Guo, L.3
Martinez, M.4
Maris, J.5
Gau, C.-L.6
Lengyel, J.A.7
Tamanoi, F.8
-
149
-
-
0038304516
-
Rheb is an essential regulator of S6K in controlling cell growth in Drosophila
-
DOI 10.1038/ncb995
-
H. Stocker, T. Radimerski, B. Schindelholz, F. Wittwer, P. Belawat, P. Daram, S. Breuer, G. Thomas, and E. Hafen Rheb is an essential regulator of S6K in controlling cell growth in Drosophila Nat. Cell Biol. 5 2003 559 565 (Pubitemid 36781091)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.6
, pp. 559-565
-
-
Stocker, H.1
Radimerski, T.2
Schindelholz, B.3
Wittwer, F.4
Belawat, P.5
Daram, P.6
Breuer, S.7
Thomas, G.8
Hafen, E.9
-
150
-
-
0032538890
-
Disruption of the p705(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase
-
H. Shima, M. Pende, Y. Chen, S. Fumagalli, G. Thomas, and S.C. Kozma Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase EMBO J. 17 1998 6649 6659 (Pubitemid 28521798)
-
(1998)
EMBO Journal
, vol.17
, Issue.22
, pp. 6649-6659
-
-
Shima, H.1
Pende, M.2
Chen, Y.3
Fumagalli, S.4
Thomas, G.5
Kozma, S.C.6
-
151
-
-
0028032894
-
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
-
DOI 10.1038/372182a0
-
H. Tamemoto, T. Kadowaki, K. Tobe, T. Yagi, H. Sakura, T. Hayakawa, Y. Terauchi, K. Ueki, Y. Kaburagi, and S. Satoh Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1 Nature 372 1994 182 186 (Pubitemid 24347838)
-
(1994)
Nature
, vol.372
, Issue.6502
, pp. 182-186
-
-
Tamemoto, H.1
Kadowaki, T.2
Tobe, K.3
Yagi, T.4
Sakura, H.5
Hayakawa, T.6
Terauchi, Y.7
Ueki, K.8
Kaburagi, Y.9
Satoh, S.10
Sekihara, H.11
Yoshioka, S.12
Horikoshi, H.13
Furuta, Y.14
Ikawa, Y.15
Kasuga, M.16
Yazaki, Y.17
Aizawa, S.18
-
152
-
-
0034982971
-
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
-
DOI 10.1101/gad.901101
-
X. Gao, and D. Pan TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth Genes Dev. 15 2001 1383 1392 (Pubitemid 32524645)
-
(2001)
Genes and Development
, vol.15
, Issue.11
, pp. 1383-1392
-
-
Gao, X.1
Pan, D.2
-
153
-
-
0033258521
-
Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB
-
J. Verdu, M.A. Buratovich, E.L. Wilder, and M.J. Birnbaum Cell-autonomous
-
(1999)
Nature Cell Biology
, vol.1
, Issue.8
, pp. 500-506
-
-
Verdu, J.1
Buratovicht, M.A.2
Wilder, E.L.3
Birnbaum, M.J.4
-
154
-
-
26944461217
-
Transcriptional feedback control of insulin receptor by dFOXO/FOXO1
-
DOI 10.1101/gad.1340505
-
O. Puig, and R. Tjian Transcriptional feedback control of insulin receptor by dFOXO/FOXO1 Genes Dev. 19 2005 2435 2446 (Pubitemid 41483691)
-
(2005)
Genes and Development
, vol.19
, Issue.20
, pp. 2435-2446
-
-
Puig, O.1
Tjian, R.2
-
155
-
-
67651230548
-
NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth
-
M.F. James, S. Han, C. Polizzano, S.R. Plotkin, B.D. Manning, A.O. Stemmer-Rachamimov, J.F. Gusella, and V. Ramesh NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth Mol. Cell Biol. 29 2009 4250 4261
-
(2009)
Mol. Cell Biol.
, vol.29
, pp. 4250-4261
-
-
James, M.F.1
Han, S.2
Polizzano, C.3
Plotkin, S.R.4
Manning, B.D.5
Stemmer-Rachamimov, A.O.6
Gusella, J.F.7
Ramesh, V.8
-
156
-
-
67651230554
-
Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling
-
M.A. Lopez-Lago, T. Okada, M.M. Murillo, N. Socci, and F.G. Giancotti Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling Mol. Cell Biol. 29 2009 4235 4249
-
(2009)
Mol. Cell Biol.
, vol.29
, pp. 4235-4249
-
-
Lopez-Lago, M.A.1
Okada, T.2
Murillo, M.M.3
Socci, N.4
Giancotti, F.G.5
-
157
-
-
80054965145
-
Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size
-
M. Xin, Y. Kim, L.B. Sutherland, X. Qi, J. McAnally, R.J. Schwartz, J.A. Richardson, R. Bassel-Duby, and E.N. Olson Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size Sci Signal. 4 2011 ra70
-
(2011)
Sci Signal.
, vol.4
-
-
Xin, M.1
Kim, Y.2
Sutherland, L.B.3
Qi, X.4
McAnally, J.5
Schwartz, R.J.6
Richardson, J.A.7
Bassel-Duby, R.8
Olson, E.N.9
-
158
-
-
33646934067
-
A Conserved MST-FOXO Signaling Pathway Mediates Oxidative-Stress Responses and Extends Life Span
-
DOI 10.1016/j.cell.2006.03.046, PII S0092867406005599
-
M.K. Lehtinen, Z. Yuan, P.R. Boag, Y. Yang, J. Villen, E.B. Becker, S. DiBacco, N. de la Iglesia, S. Gygi, and T.K. Blackwell A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span Cell 125 2006 987 1001 (Pubitemid 43795191)
-
(2006)
Cell
, vol.125
, Issue.5
, pp. 987-1001
-
-
Lehtinen, M.K.1
Yuan, Z.2
Boag, P.R.3
Yang, Y.4
Villen, J.5
Becker, E.B.E.6
DiBacco, S.7
De La Iglesia, N.8
Gygi, S.9
Blackwell, T.K.10
Bonni, A.11
-
159
-
-
65649149752
-
Regulation of neuronal cell death by MST1-FOXO1 signaling
-
Z. Yuan, M.K. Lehtinen, P. Merlo, J. Villen, S. Gygi, and A. Bonni Regulation of neuronal cell death by MST1-FOXO1 signaling J. Biol. Chem. 284 2009 11285 11292
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 11285-11292
-
-
Yuan, Z.1
Lehtinen, M.K.2
Merlo, P.3
Villen, J.4
Gygi, S.5
Bonni, A.6
-
160
-
-
37049024761
-
C-myc repression of TSC2 contributes to control of translation initiation and myc-induced transformation
-
DOI 10.1158/0008-5472.CAN-06-4351
-
M.J. Ravitz, L. Chen, M. Lynch, and E.V. Schmidt c-myc Repression of TSC2 contributes to control of translation initiation and Myc-induced transformation Cancer Res. 67 2007 11209 11217 (Pubitemid 350248546)
-
(2007)
Cancer Research
, vol.67
, Issue.23
, pp. 11209-11217
-
-
Ravitz, M.J.1
Chen, L.2
Lynch, M.3
Schmidt, E.V.4
-
161
-
-
0034614637
-
The hallmarks of cancer
-
D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70 (Pubitemid 30046295)
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
162
-
-
0035063183
-
The Rb/E2F pathway and cancer
-
J.R. Nevins The Rb/E2F pathway and cancer Hum. Mol. Genet. 10 2001 699 703 (Pubitemid 32331578)
-
(2001)
Human Molecular Genetics
, vol.10
, Issue.7
, pp. 699-703
-
-
Nevins, J.R.1
-
163
-
-
0032146274
-
The regulation of E2F by pRB-family proteins
-
N. Dyson The regulation of E2F by pRB-family proteins Genes Dev. 12 1998 2245 2262 (Pubitemid 28371346)
-
(1998)
Genes and Development
, vol.12
, Issue.15
, pp. 2245-2262
-
-
Dyson, N.1
-
164
-
-
79955416113
-
A kinase shRNA screen links LATS2 and the pRB tumor suppressor
-
K. Tschop, A.R. Conery, L. Litovchick, J.A. Decaprio, J. Settleman, E. Harlow, and N. Dyson A kinase shRNA screen links LATS2 and the pRB tumor suppressor Genes Dev. 25 2011 814 830
-
(2011)
Genes Dev.
, vol.25
, pp. 814-830
-
-
Tschop, K.1
Conery, A.R.2
Litovchick, L.3
Decaprio, J.A.4
Settleman, J.5
Harlow, E.6
Dyson, N.7
-
165
-
-
79951692812
-
Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit
-
B.N. Nicolay, B. Bayarmagnai, A.B. Islam, N. Lopez-Bigas, and M.V. Frolov Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit Genes Dev. 25 2011 323 335
-
(2011)
Genes Dev.
, vol.25
, pp. 323-335
-
-
Nicolay, B.N.1
Bayarmagnai, B.2
Islam, A.B.3
Lopez-Bigas, N.4
Frolov, M.V.5
-
166
-
-
79551514734
-
E2F1 regulates cellular growth by mTORC1 signaling
-
S. Real, N. Meo-Evoli, L. Espada, and A. Tauler E2F1 regulates cellular growth by mTORC1 signaling PLoS One 6 2011 e16163
-
(2011)
PLoS One
, vol.6
, pp. 16163
-
-
Real, S.1
Meo-Evoli, N.2
Espada, L.3
Tauler, A.4
|