cAMP/PKA regulates osteogenesis, adipogenesis and ratio of RANKL/OPG mRNA expression in mesenchymal stem cells by suppressing leptin

PLoS ONE

Volumn 3, Issue 2, 2008, Pages

  Yang, Der Chih ^a   Tsay, Huey Jen ^a   Lin, Shan Yang ^a   Chiou, Shih Hwa ^a   Li, Mei Jane ^a   Chang, Tai Jay ^a   Hung, Shih Chieh ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FORSKOLIN; ISOBUTYLMETHYLXANTHINE; LEPTIN; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPONTIN; OSTEOPROTEGERIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; TRANSCRIPTION FACTOR RUNX2;

ADIPOGENESIS; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE METABOLISM; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VIVO STUDY; MESENCHYMAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOCLAST; OSTEOLYSIS; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION; ZEBRA FISH; ANIMAL; BONE; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; FEMALE; GENETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

DANIO RERIO;

ADIPOGENESIS; ANIMALS; BONE AND BONES; CELL DIFFERENTIATION; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FEMALE; HUMANS; LEPTIN; MESENCHYMAL STEM CELLS; MIDDLE AGED; OSTEOGENESIS; OSTEOPROTEGERIN; RANK LIGAND; RNA, MESSENGER; SIGNAL TRANSDUCTION; ZEBRAFISH;

EID: 45249122818     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001540     Document Type: Article

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