Transcriptional analysis of pluripotency reveals the hippo pathway as a barrier to reprogramming

Human Molecular Genetics

Volumn 21, Issue 9, 2012, Pages 2054-2067

  Qin, Han ^a,b   Blaschke, Kathryn ^a,b   Wei, Grace ^a   Ohi, Yuki ^a,b   Blouin, Laure ^a,b   Qi, Zhongxia ^a   Yu, Jingwei ^a   Yeh, Ru Fang ^b,c   Hebrok, Matthias ^a   Ramalho santos, Miguel ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HIPPO PROTEIN; LATS2 PROTEIN; PROTEIN P53; TAZ PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; YAP PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE SILENCING; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GERMLINE MICRONUCLEUS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; RNA INTERFERENCE; SOMATIC CELL; TRANSCRIPTION REGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; EMBRYONIC STEM CELLS; GENE EXPRESSION PROFILING; GENE KNOCKDOWN TECHNIQUES; GENES, P53; GERM CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; NEOPLASMS, GERM CELL AND EMBRYONAL; NUCLEAR PROTEINS; NUCLEAR REPROGRAMMING; PHOSPHOPROTEINS; PLURIPOTENT STEM CELLS; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

IPS;

EID: 84859235472     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds023     Document Type: Article

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