PTH-induced actin depolymerization increases mechanosensitive channel activity to enhance mechanically stimulated Ca2+ signaling in osteoblasts

Journal of Bone and Mineral Research

Volumn 21, Issue 11, 2006, Pages 1729-1737

  Zhang, Jinsong ^a,b   Ryder, Kimberly D ^a   Bethel, Jody A ^a   Ramirez, Raymond ^a   Duncan, Randall L ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF DELAWARE   (United States)

Author keywords

Actin cytoskeleton; Fluid shear; Intracellular Ca2+; Mechanotransduction; Osteoblasts; PTH

Indexed keywords

ACTIN; CALCIUM; COLLAGEN TYPE 1; CYTOCHALASIN D; GADOLINIUM; ION CHANNEL; PARATHYROID HORMONE; PHALLOIDIN;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONTROLLED STUDY; CYTOSKELETON; DEPOLYMERIZATION; MECHANICAL STIMULATION; MOUSE; NONHUMAN; OSTEOBLAST; PATCH CLAMP; RAT; SHEAR STRESS;

ACTINS; ANIMALS; CALCIUM; CATTLE; CELL LINE; CYTOCHALASIN D; CYTOSKELETON; IMMUNOHISTOCHEMISTRY; MICE; MICROSCOPY, FLUORESCENCE; MODELS, STATISTICAL; OSTEOBLASTS; PARATHYROID HORMONE; PATCH-CLAMP TECHNIQUES; SIGNAL TRANSDUCTION;

EID: 33846405735     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.060722     Document Type: Article

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