Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling

Biochemical Journal

Volumn 432, Issue 3, 2010, Pages 461-472

  Oka, Tsutomu ^a   Remue, Eline ^b   Meerschaert, Kris ^b   Vanloo, Berlinda ^b   Boucherie, Ciska ^b   Gfeller, David ^c   Bader, Gary D ^c   Sidhu, Sachdev S ^c   Vandekerckhove, Jöel ^b   Gettemans, Jan ^b   Sudol, Marius ^a,d  

^a WEIS CENTER FOR RESEARCH   (United States)

^b GHENT UNIVERSITY   (Belgium)

^c UNIVERSITY OF TORONTO   (Canada)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Hippo pathway; Nuclear translocation; PDZ domain; Yes kinase associated protein 2 (YAP2); Zona occludens protein

Indexed keywords

HIPPO PATHWAY; NUCLEAR TRANSLOCATIONS; PDZ DOMAINS; YES KINASE-ASSOCIATED PROTEIN 2 (YAP2); ZONA OCCLUDENS;

CELL DEATH; MAMMALS;

PROTEINS;

PROTEIN KINASE YES; PROTEIN ZO2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER THERAPY; CELL NUCLEUS; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PDZ DOMAIN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TUMOR SUPPRESSOR GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL ADHESION; CELL LINE; CELL NUCLEUS; CELL PROLIFERATION; DOGS; GENES, REPORTER; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; MEMBRANE PROTEINS; MUTANT PROTEINS; PDZ DOMAINS; PHOSPHOPROTEINS; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFECTION;

MAMMALIA;

EID: 78649892579     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20100870     Document Type: Article

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