-
1
-
-
77958494807
-
LATS tumor suppressor: A new governor of cellular homeostasis
-
Visser S, Yang X (2010) LATS tumor suppressor: A new governor of cellular homeostasis. Cell Cycle 9:3892-3903.
-
(2010)
Cell Cycle
, vol.9
, pp. 3892-3903
-
-
Visser, S.1
Yang, X.2
-
2
-
-
0032829339
-
The role of lats in cell cycle regulation and tumorigenesis
-
DOI 10.1016/S0304-419X(99)00021-9, PII S0304419X99000219
-
Turenchalk GS, St John MA, Tao W, Xu T (1999) The role of lats in cell cycle regulation and tumorigenesis. Biochim Biophys Acta 1424:M9-M16. (Pubitemid 29488711)
-
(1999)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1424
, Issue.2-3
-
-
Turenchalk, G.S.1
St, J.M.A.R.2
Tao, W.3
Xu, T.4
-
3
-
-
0028929414
-
Identifying tumor suppressors in genetic mosaics: The Drosophila lats gene encodes a putative protein kinase
-
Xu T, Wang W, Zhang S, Stewart RA, Yu W (1995) Identifying tumor suppressors in genetic mosaics: The Drosophila lats gene encodes a putative protein kinase. Development 121:1053-1063.
-
(1995)
Development
, vol.121
, pp. 1053-1063
-
-
Xu, T.1
Wang, W.2
Zhang, S.3
Stewart, R.A.4
Yu, W.5
-
4
-
-
0028902594
-
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
-
Justice RW, Zilian O, Woods DF, Noll M, Bryant PJ (1995) The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev 9:534-546.
-
(1995)
Genes Dev
, vol.9
, pp. 534-546
-
-
Justice, R.W.1
Zilian, O.2
Woods, D.F.3
Noll, M.4
Bryant, P.J.5
-
5
-
-
0032907439
-
Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
-
DOI 10.1038/5965
-
St John MA, et al. (1999) Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction. Nat Genet 21:182-186. (Pubitemid 29070363)
-
(1999)
Nature Genetics
, vol.21
, Issue.2
, pp. 182-186
-
-
St, J.M.A.R.1
Tao, W.2
Fei, X.3
Fukumoto, R.4
Carcangiu, M.L.5
Brownstein, D.G.6
Parlow, A.F.7
McGrath, J.8
Xu, T.9
-
6
-
-
85047699404
-
LATS1 tumor suppressor regulates G2/M transition and apoptosis
-
DOI 10.1038/sj/onc/1205174
-
Xia H, et al. (2002) LATS1 tumor suppressor regulates G2/M transition and apoptosis. Oncogene 21:1233-1241. (Pubitemid 34185240)
-
(2002)
Oncogene
, vol.21
, Issue.8
, pp. 1233-1241
-
-
Xia, H.1
Qi, H.2
Li, Y.3
Pei, J.4
Barton, J.5
Blackstad, M.6
Xu, T.7
Tao, W.8
-
7
-
-
0035807242
-
2/M arrest or apoptosis
-
DOI 10.1038/sj.onc.1204817
-
Yang X, Li DM, Chen W, Xu T (2001) Human homologue of Drosophila lats, LATS1, negatively regulate growth by inducing G(2)/M arrest or apoptosis. Oncogene 20:6516-6523. (Pubitemid 32980276)
-
(2001)
Oncogene
, vol.20
, Issue.45
, pp. 6516-6523
-
-
Yang, X.1
Li, D.-M.2
Chen, W.3
Xu, T.4
-
8
-
-
0034702214
-
Molecular cloning of a novel human protein kinase, kpm, that is homologous to warts/lats, a Drosophila tumor suppressor
-
Hori T, Takaori-Kondo A, Kamikubo Y, Uchiyama T (2000) Molecular cloning of a novel human protein kinase, kpm, that is homologous to warts/lats, a Drosophila tumor suppressor. Oncogene 19:3101-3109. (Pubitemid 30438467)
-
(2000)
Oncogene
, vol.19
, Issue.27
, pp. 3101-3109
-
-
Hori, T.1
Takaori-Kondo, A.2
Kamikubo, Y.3
Uchiyama, T.4
-
9
-
-
0036800399
-
Molecular alterations of h-warts/LATS1 tumor suppressor in human soft tissue sarcoma
-
Hisaoka M, Tanaka A, Hashimoto H (2002) Molecular alterations of h-warts/LATS1 tumor suppressor in human soft tissue sarcoma. Lab Invest 82:1427-1435. (Pubitemid 35191546)
-
(2002)
Laboratory Investigation
, vol.82
, Issue.10
, pp. 1427-1435
-
-
Hisaoka, M.1
Tanaka, A.2
Hashimoto, H.3
-
10
-
-
14644420898
-
Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers
-
DOI 10.1158/1078-0432.CCR-04-1773
-
Takahashi Y, et al. (2005) Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers. Clin Cancer Res 11:1380-1385. (Pubitemid 40315216)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.4
, pp. 1380-1385
-
-
Takahashi, Y.1
Miyoshi, Y.2
Takahata, C.3
Irahara, N.4
Taguchi, T.5
Tamaki, Y.6
Noguchi, S.7
-
11
-
-
33751019980
-
Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma
-
DOI 10.1016/j.neures.2006.09.006, PII S0168010206002240
-
Jiang Z, et al. (2006) Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma. Neurosci Res 56:450-458. (Pubitemid 44750270)
-
(2006)
Neuroscience Research
, vol.56
, Issue.4
, pp. 450-458
-
-
Jiang, Z.1
Li, X.2
Hu, J.3
Zhou, W.4
Jiang, Y.5
Li, G.6
Lu, D.7
-
13
-
-
33847206401
-
The Salvador-Warts-Hippo pathway - An emerging tumour-suppressor network
-
Harvey K, Tapon N (2007) The Salvador-Warts-Hippo pathway - An emerging tumour-suppressor network. Nat Rev Cancer 7:182-191.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 182-191
-
-
Harvey, K.1
Tapon, N.2
-
14
-
-
39849097306
-
The Emerging Role of the Hippo Pathway in Cell Contact Inhibition, Organ Size Control, and Cancer Development in Mammals
-
DOI 10.1016/j.ccr.2008.02.011, PII S1535610808000470
-
Zeng Q, Hong W (2008) The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals. Cancer Cell 13:188-192. (Pubitemid 351318373)
-
(2008)
Cancer Cell
, vol.13
, Issue.3
, pp. 188-192
-
-
Zeng, Q.1
Hong, W.2
-
15
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
DOI 10.1101/gad.1602907
-
Zhao B, et al. (2007) Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev 21:2747-2761. (Pubitemid 350070721)
-
(2007)
Genes and Development
, vol.21
, Issue.21
, pp. 2747-2761
-
-
Zhao, B.1
Wei, X.2
Li, W.3
Udan, R.S.4
Yang, Q.5
Kim, J.6
Xie, J.7
Ikenoue, T.8
Yu, J.9
Li, L.10
Zheng, P.11
Ye, K.12
Chinnaiyan, A.13
Halder, G.14
Lai, Z.-C.15
Guan, K.-L.16
-
17
-
-
34547101487
-
Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-array
-
DOI 10.1038/sj.onc.1210330, PII 1210330
-
Nakaya K, et al. (2007) Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-array. Oncogene 26:5300-5308. (Pubitemid 47237625)
-
(2007)
Oncogene
, vol.26
, Issue.36
, pp. 5300-5308
-
-
Nakaya, K.1
Yamagata, H.D.2
Arita, N.3
Nakashiro, K.-I.4
Nose, M.5
Miki, T.6
Hamakawa, H.7
-
18
-
-
42349088170
-
A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells
-
Chan SW, et al. (2008) A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. Cancer Res 68:2592-2598.
-
(2008)
Cancer Res
, vol.68
, pp. 2592-2598
-
-
Chan, S.W.1
-
19
-
-
41949138130
-
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
-
Hao Y, Chun A, Cheung K, Rashidi B, Yang X (2008) Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J Biol Chem 283:5496-5509.
-
(2008)
J Biol Chem
, vol.283
, pp. 5496-5509
-
-
Hao, Y.1
Chun, A.2
Cheung, K.3
Rashidi, B.4
Yang, X.5
-
20
-
-
55549098921
-
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
-
Oka T, Mazack V, Sudol M (2008) Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). J Biol Chem 283:27534-27546.
-
(2008)
J Biol Chem
, vol.283
, pp. 27534-27546
-
-
Oka, T.1
Mazack, V.2
Sudol, M.3
-
21
-
-
33646422520
-
The human tumour suppressor LATS1 is activated by human MOB1 at the membrane
-
Hergovich A, Schmitz D, Hemmings BA (2006) The human tumour suppressor LATS1 is activated by human MOB1 at the membrane. Biochem Biophys Res Commun 345:50-58.
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 50-58
-
-
Hergovich, A.1
Schmitz, D.2
Hemmings, B.A.3
-
22
-
-
77949896337
-
Molecular characterization of human homologs of yeast MOB1
-
Chow A, Hao Y, Yang X (2010) Molecular characterization of human homologs of yeast MOB1. Int J Cancer 126:2079-2089.
-
(2010)
Int J Cancer
, vol.126
, pp. 2079-2089
-
-
Chow, A.1
Hao, Y.2
Yang, X.3
-
23
-
-
45449094801
-
Itch: A HECT-type E3 ligase regulating immunity, skin and cancer
-
DOI 10.1038/cdd.2008.60, PII CDD200860, Special Issue to celebrate Richard Lockshin's 70th Birthday
-
Melino G, et al. (2008) Itch: A HECT-type E3 ligase regulating immunity, skin and cancer. Cell Death Differ 15:1103-1112. (Pubitemid 351850962)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.7
, pp. 1103-1112
-
-
Melino, G.1
Gallagher, E.2
Aqeilan, R.I.3
Knight, R.4
Peschiaroli, A.5
Rossi, M.6
Scialpi, F.7
Malatesta, M.8
Zocchi, L.9
Browne, G.10
Ciechanover, A.11
Bernassola, F.12
-
24
-
-
0037138411
-
WW and SH3 domains, two different scaffolds to recognize proline-rich ligands
-
DOI 10.1016/S0014-5793(01)03290-2, PII S0014579301032902
-
Macias MJ, Wiesner S, Sudol M (2002) WW and SH3 domains, two different scaffolds to recognize proline-rich ligands. FEBS Lett 513:30-37. (Pubitemid 34242975)
-
(2002)
FEBS Letters
, vol.513
, Issue.1
, pp. 30-37
-
-
Macias, M.J.1
Wiesner, S.2
Sudol, M.3
-
25
-
-
44349122993
-
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: Tipping the scales of cancer
-
DOI 10.1038/nrc2396, PII NRC2396
-
Frescas D, Pagano M (2008) Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer. Nat Rev Cancer 8:438-449. (Pubitemid 351744963)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.6
, pp. 438-449
-
-
Frescas, D.1
Pagano, M.2
-
26
-
-
70350416086
-
Identification of LATS transcriptional targets in HeLa cells using whole human genome oligonucleotide microarray
-
Visser S, Yang X (2010) Identification of LATS transcriptional targets in HeLa cells using whole human genome oligonucleotide microarray. Gene 449:22-29.
-
(2010)
Gene
, vol.449
, pp. 22-29
-
-
Visser, S.1
Yang, X.2
-
27
-
-
47549095853
-
TEAD mediates YAP-dependent gene induction and growth control
-
DOI 10.1101/gad.1664408
-
Zhao B, et al. (2008) TEAD mediates YAP-dependent gene induction and growth control. Genes Dev 22:1962-1971. (Pubitemid 352008643)
-
(2008)
Genes and Development
, vol.22
, Issue.14
, pp. 1962-1971
-
-
Zhao, B.1
Ye, X.2
Yu, J.3
Li, L.4
Li, W.5
Li, S.6
Yu, J.7
Lin, J.D.8
Wang, C.-Y.9
Chinnaiyan, A.M.10
Lai, Z.-C.11
Guan, K.-L.12
-
28
-
-
42349084868
-
Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway
-
DOI 10.1158/0008-5472.CAN-07-6205
-
Zhang J, Smolen GA, Haber DA (2008) Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway. Cancer Res 68:2789-2794. (Pubitemid 351556277)
-
(2008)
Cancer Research
, vol.68
, Issue.8
, pp. 2789-2794
-
-
Zhang, J.1
Smolen, G.A.2
Haber, D.A.3
-
29
-
-
45849153870
-
The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development
-
DOI 10.1016/j.ccr.2008.06.001, PII S1535610808001918
-
Bernassola F, Karin M, Ciechanover A, Melino G (2008) The HECT family of E3 ubiquitin ligases: Multiple players in cancer development. Cancer Cell 14:10-21. (Pubitemid 351885498)
-
(2008)
Cancer Cell
, vol.14
, Issue.1
, pp. 10-21
-
-
Bernassola, F.1
Karin, M.2
Ciechanover, A.3
Melino, G.4
-
30
-
-
55549085229
-
A regulatory circuit controlling Itch-mediated p73 degradation by Runx
-
Levy D, Reuven N, Shaul Y (2008) A regulatory circuit controlling Itch-mediated p73 degradation by Runx. J Biol Chem 283:27462-27468.
-
(2008)
J Biol Chem
, vol.283
, pp. 27462-27468
-
-
Levy, D.1
Reuven, N.2
Shaul, Y.3
-
31
-
-
5044225158
-
Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase itch
-
DOI 10.1126/science.1099414
-
Gao M, et al. (2004) Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch. Science 306:271-275. (Pubitemid 39336871)
-
(2004)
Science
, vol.306
, Issue.5694
, pp. 271-275
-
-
Gao, M.1
Labuda, T.2
Xia, Y.3
Gallagher, E.4
Fang, D.5
Liu, Y.-C.6
Karin, M.7
-
32
-
-
32444437676
-
Activation of the E3 ubiquitin ligase Itch through a phosphorylation- Induced conformational change
-
DOI 10.1073/pnas.0510664103
-
Gallagher E, Gao M, Liu YC, Karin M (2006) Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change. Proc Natl Acad Sci USA 103:1717-1722. (Pubitemid 43228759)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.6
, pp. 1717-1722
-
-
Gallagher, E.1
Gao, M.2
Liu, Y.-C.3
Karin, M.4
-
33
-
-
29544433771
-
Negative regulation of the E3 ubiquitin ligase Itch via Fyn-mediated tyrosine phosphorylation
-
DOI 10.1016/j.molcel.2005.11.014, PII S1097276505018010
-
Yang C, et al. (2006) Negative regulation of the E3 ubiquitin ligase itch via Fyn-mediated tyrosine phosphorylation. Mol Cell 21:135-141. (Pubitemid 43017855)
-
(2006)
Molecular Cell
, vol.21
, Issue.1
, pp. 135-141
-
-
Yang, C.1
Zhou, W.2
Jeon, M.-S.3
Demydenko, D.4
Harada, Y.5
Zhou, H.6
Liu, Y.-C.7
|