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Volumn 19, Issue 8, 2012, Pages 955-962

Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; LYSOPHOSPHATIDIC ACID; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SERINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; TRANSCRIPTION FACTOR YAP1;

EID: 84865455267     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2012.07.005     Document Type: Article
Times cited : (213)

References (54)
  • 1
    • 35848935411 scopus 로고    scopus 로고
    • HDL serves as a S1P signaling platform mediating a multitude of cardiovascular effects
    • DOI 10.1194/jlr.R700011-JLR200
    • K.M. Argraves, and W.S. Argraves HDL serves as a S1P signaling platform mediating a multitude of cardiovascular effects J. Lipid Res. 48 2007 2325 2333 (Pubitemid 350058744)
    • (2007) Journal of Lipid Research , vol.48 , Issue.11 , pp. 2325-2333
    • Argraves, K.M.1    Argraves, W.S.2
  • 2
    • 57449095848 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate mediates transcriptional regulation of key targets associated with survival, proliferation, and pluripotency in human embryonic stem cells
    • K. Avery, S. Avery, J. Shepherd, P.R. Heath, and H. Moore Sphingosine-1-phosphate mediates transcriptional regulation of key targets associated with survival, proliferation, and pluripotency in human embryonic stem cells Stem Cells Dev. 17 2008 1195 1205
    • (2008) Stem Cells Dev. , vol.17 , pp. 1195-1205
    • Avery, K.1    Avery, S.2    Shepherd, J.3    Heath, P.R.4    Moore, H.5
  • 3
    • 79961063553 scopus 로고    scopus 로고
    • A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription
    • Y. Bao, K. Nakagawa, Z. Yang, M. Ikeda, K. Withanage, M. Ishigami-Yuasa, Y. Okuno, S. Hata, H. Nishina, and Y. Hata A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription J. Biochem. 150 2011 199 208
    • (2011) J. Biochem. , vol.150 , pp. 199-208
    • Bao, Y.1    Nakagawa, K.2    Yang, Z.3    Ikeda, M.4    Withanage, K.5    Ishigami-Yuasa, M.6    Okuno, Y.7    Hata, S.8    Nishina, H.9    Hata, Y.10
  • 5
    • 33750611115 scopus 로고    scopus 로고
    • Fat Cadherin Modulates Organ Size in Drosophila via the Salvador/Warts/Hippo Signaling Pathway
    • DOI 10.1016/j.cub.2006.09.045, PII S0960982206022779
    • F.C. Bennett, and K.F. Harvey Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway Curr. Biol. 16 2006 2101 2110 (Pubitemid 44692100)
    • (2006) Current Biology , vol.16 , Issue.21 , pp. 2101-2110
    • Bennett, F.C.1    Harvey, K.F.2
  • 6
    • 67649770134 scopus 로고    scopus 로고
    • TEADs mediate nuclear retention of TAZ to promote oncogenic transformation
    • S.W. Chan, C.J. Lim, L.S. Loo, Y.F. Chong, C. Huang, and W. Hong TEADs mediate nuclear retention of TAZ to promote oncogenic transformation J. Biol. Chem. 284 2009 14347 14358
    • (2009) J. Biol. Chem. , vol.284 , pp. 14347-14358
    • Chan, S.W.1    Lim, C.J.2    Loo, L.S.3    Chong, Y.F.4    Huang, C.5    Hong, W.6
  • 8
    • 33749125438 scopus 로고    scopus 로고
    • Delineation of a Fat tumor suppressor pathway
    • DOI 10.1038/ng1887, PII NG1887
    • E. Cho, Y. Feng, C. Rauskolb, S. Maitra, R. Fehon, and K.D. Irvine Delineation of a fat tumor suppressor pathway Nat. Genet. 38 2006 1142 1150 (Pubitemid 44470359)
    • (2006) Nature Genetics , vol.38 , Issue.10 , pp. 1142-1150
    • Cho, E.1    Feng, Y.2    Rauskolb, C.3    Maitra, S.4    Fehon, R.5    Irvine, K.D.6
  • 10
    • 9644255879 scopus 로고    scopus 로고
    • Regulation of connective tissue growth factor (CTGF/CCN2) gene transcription and mRNA stability in smooth muscle cells: Involvement of RhoA GTPase and p38 MAP kinase and sensitivity to actin dynamics
    • DOI 10.1111/j.1432-1033.2004.04382.x
    • I. Chowdhury, and B. Chaqour Regulation of connective tissue growth factor (CTGF/CCN2) gene transcription and mRNA stability in smooth muscle cells. Involvement of RhoA GTPase and p38 MAP kinase and sensitivity to actin dynamics Eur. J. Biochem. 271 2004 4436 4450 (Pubitemid 39576561)
    • (2004) European Journal of Biochemistry , vol.271 , Issue.22 , pp. 4436-4450
    • Chowdhury, I.1    Chaqour, B.2
  • 13
    • 79956327002 scopus 로고    scopus 로고
    • Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
    • B.G. Fernández, P. Gaspar, C. Brás-Pereira, B. Jezowska, S.R. Rebelo, and F. Janody Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila Development 138 2011 2337 2346
    • (2011) Development , vol.138 , pp. 2337-2346
    • Fernández, B.G.1    Gaspar, P.2    Brás-Pereira, C.3    Jezowska, B.4    Rebelo, S.R.5    Janody, F.6
  • 14
    • 40849086201 scopus 로고    scopus 로고
    • SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila
    • Y. Goulev, J.D. Fauny, B. Gonzalez-Marti, D. Flagiello, J. Silber, and A. Zider SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila Curr. Biol. 18 2008 435 441
    • (2008) Curr. Biol. , vol.18 , pp. 435-441
    • Goulev, Y.1    Fauny, J.D.2    Gonzalez-Marti, B.3    Flagiello, D.4    Silber, J.5    Zider, A.6
  • 15
    • 33847206401 scopus 로고    scopus 로고
    • The Salvador-Warts-Hippo pathway - An emerging tumour-suppressor network
    • K. Harvey, and N. Tapon The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network Nat. Rev. Cancer 7 2007 182 191
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 182-191
    • Harvey, K.1    Tapon, N.2
  • 16
    • 0042733354 scopus 로고    scopus 로고
    • The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
    • DOI 10.1016/S0092-8674(03)00557-9
    • K.F. Harvey, C.M. Pfleger, and I.K. Hariharan The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis Cell 114 2003 457 467 (Pubitemid 37100994)
    • (2003) Cell , vol.114 , Issue.4 , pp. 457-467
    • Harvey, K.F.1    Pfleger, C.M.2    Hariharan, I.K.3
  • 17
    • 0142123293 scopus 로고    scopus 로고
    • The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
    • DOI 10.1101/gad.1134003
    • J. Jia, W. Zhang, B. Wang, R. Trinko, and J. Jiang The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis Genes Dev. 17 2003 2514 2519 (Pubitemid 37271421)
    • (2003) Genes and Development , vol.17 , Issue.20 , pp. 2514-2519
    • Jia, J.1    Zhang, W.2    Wang, B.3    Trinko, R.4    Jiang, J.5
  • 19
    • 0035943594 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate may be a major component of plasma lipoproteins responsible for the cytoprotective actions in human umbilical vein endothelial cells
    • T. Kimura, K. Sato, A. Kuwabara, H. Tomura, M. Ishiwara, I. Kobayashi, M. Ui, and F. Okajima Sphingosine 1-phosphate may be a major component of plasma lipoproteins responsible for the cytoprotective actions in human umbilical vein endothelial cells J. Biol. Chem. 276 2001 31780 31785
    • (2001) J. Biol. Chem. , vol.276 , pp. 31780-31785
    • Kimura, T.1    Sato, K.2    Kuwabara, A.3    Tomura, H.4    Ishiwara, M.5    Kobayashi, I.6    Ui, M.7    Okajima, F.8
  • 20
    • 54249151827 scopus 로고    scopus 로고
    • Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2
    • M.H. Li, T. Sanchez, A. Pappalardo, K.R. Lynch, T. Hla, and F. Ferrer Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2 Mol. Cancer Res. 6 2008 1649 1656
    • (2008) Mol. Cancer Res. , vol.6 , pp. 1649-1656
    • Li, M.H.1    Sanchez, T.2    Pappalardo, A.3    Lynch, K.R.4    Hla, T.5    Ferrer, F.6
  • 22
    • 84862605178 scopus 로고    scopus 로고
    • Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
    • Y. Liu-Chittenden, B. Huang, J.S. Shim, Q. Chen, S.J. Lee, R.A. Anders, J.O. Liu, and D. Pan Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP Genes Dev. 26 2012 1300 1305
    • (2012) Genes Dev. , vol.26 , pp. 1300-1305
    • Liu-Chittenden, Y.1    Huang, B.2    Shim, J.S.3    Chen, Q.4    Lee, S.J.5    Anders, R.A.6    Liu, J.O.7    Pan, D.8
  • 23
    • 0034672133 scopus 로고    scopus 로고
    • Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions
    • DOI 10.1042/0264-6021:3520809
    • N. Murata, K. Sato, J. Kon, H. Tomura, M. Yanagita, A. Kuwabara, M. Ui, and F. Okajima Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions Biochem. J. 352 2000 809 815 (Pubitemid 32015038)
    • (2000) Biochemical Journal , vol.352 , Issue.3 , pp. 809-815
    • Murata, N.1    Sato, K.2    Kon, J.3    Tomura, H.4    Yanagita, M.5    Kuwabara, A.6    Ul, M.7    Okajima, F.8
  • 24
    • 60849138138 scopus 로고    scopus 로고
    • Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling
    • M. Ota, and H. Sasaki Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling Development 135 2008 4059 4069
    • (2008) Development , vol.135 , pp. 4059-4069
    • Ota, M.1    Sasaki, H.2
  • 25
    • 77957883342 scopus 로고    scopus 로고
    • The hippo signaling pathway in development and cancer
    • D. Pan The hippo signaling pathway in development and cancer Dev. Cell 19 2010 491 505
    • (2010) Dev. Cell , vol.19 , pp. 491-505
    • Pan, D.1
  • 26
    • 0141505119 scopus 로고    scopus 로고
    • The salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
    • DOI 10.1038/ncb1051
    • S. Pantalacci, N. Tapon, and P. Léopold The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila Nat. Cell Biol. 5 2003 921 927 (Pubitemid 37220699)
    • (2003) Nature Cell Biology , vol.5 , Issue.10 , pp. 921-927
    • Pantalacci, S.1    Tapon, N.2    Leopold, P.3
  • 27
    • 80054037863 scopus 로고    scopus 로고
    • Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer
    • D. Pchejetski, T. Böhler, J. Stebbing, and J. Waxman Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer Nat. Rev. Urol. 8 2011 569 678
    • (2011) Nat. Rev. Urol. , vol.8 , pp. 569-678
    • Pchejetski, D.1    Böhler, T.2    Stebbing, J.3    Waxman, J.4
  • 28
    • 77953966511 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and cancer
    • N.J. Pyne, and S. Pyne Sphingosine 1-phosphate and cancer Nat. Rev. Cancer 10 2010 489 503
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 489-503
    • Pyne, N.J.1    Pyne, S.2
  • 29
    • 48749101754 scopus 로고    scopus 로고
    • Morphogen control of wing growth through the Fat signaling pathway
    • D. Rogulja, C. Rauskolb, and K.D. Irvine Morphogen control of wing growth through the Fat signaling pathway Dev. Cell 15 2008 309 321
    • (2008) Dev. Cell , vol.15 , pp. 309-321
    • Rogulja, D.1    Rauskolb, C.2    Irvine, K.D.3
  • 30
    • 21844457949 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and its receptors: An autocrine and paracrine network
    • DOI 10.1038/nri1650
    • H. Rosen, and E.J. Goetzl Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network Nat. Rev. Immunol. 5 2005 560 570 (Pubitemid 40961333)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.7 , pp. 560-570
    • Rosen, H.1    Goetzl, E.J.2
  • 33
    • 0018257847 scopus 로고
    • Plasma, apolipoprotein A-I and A-II levels in hyperlipidemia
    • G. Schonfeld, A. Bailey, and R. Steelman Plasma, apolipoprotein, A-I and A-II levels in hyperlipidemia Lipids 13 1978 951 959 (Pubitemid 9085241)
    • (1978) Lipids , vol.13 , Issue.12 , pp. 951-959
    • Schonfeld, G.1    Bailey, A.2    Steelman, R.3
  • 34
    • 33750624298 scopus 로고    scopus 로고
    • The Tumor-Suppressor Gene fat Controls Tissue Growth Upstream of Expanded in the Hippo Signaling Pathway
    • DOI 10.1016/j.cub.2006.09.004, PII S0960982206021609
    • E. Silva, Y. Tsatskis, L. Gardano, N. Tapon, and H. McNeill The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway Curr. Biol. 16 2006 2081 2089 (Pubitemid 44692094)
    • (2006) Current Biology , vol.16 , Issue.21 , pp. 2081-2089
    • Silva, E.1    Tsatskis, Y.2    Gardano, L.3    Tapon, N.4    McNeill, H.5
  • 35
    • 0038218405 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate: An enigmatic signalling lipid
    • DOI 10.1038/nrm1103
    • S. Spiegel, and S. Milstien Sphingosine-1-phosphate: an enigmatic signalling lipid Nat. Rev. Mol. Cell Biol. 4 2003 397 407 (Pubitemid 36565571)
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , Issue.5 , pp. 397-407
    • Spiegel, S.1    Milstien, S.2
  • 36
    • 0037162714 scopus 로고    scopus 로고
    • Salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
    • DOI 10.1016/S0092-8674(02)00824-3
    • N. Tapon, K.F. Harvey, D.W. Bell, D.C. Wahrer, T.A. Schiripo, D.A. Haber, and I.K. Hariharan salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines Cell 110 2002 467 478 (Pubitemid 35232290)
    • (2002) Cell , vol.110 , Issue.4 , pp. 467-478
    • Tapon, N.1    Harvey, K.F.2    Bell, D.W.3    Wahrer, D.C.R.4    Schiripo, T.A.5    Haber, D.A.6    Hariharan, I.K.7
  • 37
    • 34247134640 scopus 로고    scopus 로고
    • Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways
    • DOI 10.1016/j.ydbio.2007.02.004, PII S0012160607001005
    • D.M. Tyler, and N.E. Baker Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways Dev. Biol. 305 2007 187 201 (Pubitemid 46589414)
    • (2007) Developmental Biology , vol.305 , Issue.1 , pp. 187-201
    • Tyler, D.M.1    Baker, N.E.2
  • 38
    • 0141616617 scopus 로고    scopus 로고
    • Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
    • DOI 10.1038/ncb1050
    • R.S. Udan, M. Kango-Singh, R. Nolo, C. Tao, and G. Halder Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway Nat. Cell Biol. 5 2003 914 920 (Pubitemid 37220698)
    • (2003) Nature Cell Biology , vol.5 , Issue.10 , pp. 914-920
    • Udan, R.S.1    Kango-Singh, M.2    Nolo, R.3    Tao, C.4    Halder, G.5
  • 39
    • 80051923057 scopus 로고    scopus 로고
    • Hippo pathway regulation by cell morphology and stress fibers
    • K. Wada, K. Itoga, T. Okano, S. Yonemura, and H. Sasaki Hippo pathway regulation by cell morphology and stress fibers Development 138 2011 3907 3914
    • (2011) Development , vol.138 , pp. 3907-3914
    • Wada, K.1    Itoga, K.2    Okano, T.3    Yonemura, S.4    Sasaki, H.5
  • 40
    • 32444451016 scopus 로고    scopus 로고
    • Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry
    • DOI 10.1021/ac051312t
    • E.J. Want, G. O'Maille, C.A. Smith, T.R. Brandon, W. Uritboonthai, C. Qin, S.A. Trauger, and G. Siuzdak Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry Anal. Chem. 78 2006 743 752 (Pubitemid 43228581)
    • (2006) Analytical Chemistry , vol.78 , Issue.3 , pp. 743-752
    • Want, E.J.1    O'Maille, G.2    Smith, C.A.3    Brandon, T.R.4    Uritboonthai, W.5    Qin, C.6    Trauger, S.A.7    Siuzdak, G.8
  • 41
    • 33750614445 scopus 로고    scopus 로고
    • The Fat Cadherin Acts through the Hippo Tumor-Suppressor Pathway to Regulate Tissue Size
    • DOI 10.1016/j.cub.2006.09.005, PII S0960982206021920
    • M. Willecke, F. Hamaratoglu, M. Kango-Singh, R. Udan, C.L. Chen, C. Tao, X. Zhang, and G. Halder The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size Curr. Biol. 16 2006 2090 2100 (Pubitemid 44692095)
    • (2006) Current Biology , vol.16 , Issue.21 , pp. 2090-2100
    • Willecke, M.1    Hamaratoglu, F.2    Kango-Singh, M.3    Udan, R.4    Chen, C.-l.5    Tao, C.6    Zhang, X.7    Halder, G.8
  • 42
    • 54449090287 scopus 로고    scopus 로고
    • Boundaries of Dachsous Cadherin activity modulate the Hippo signaling pathway to induce cell proliferation
    • M. Willecke, F. Hamaratoglu, L. Sansores-Garcia, C. Tao, and G. Halder Boundaries of Dachsous Cadherin activity modulate the Hippo signaling pathway to induce cell proliferation Proc. Natl. Acad. Sci. USA 105 2008 14897 14902
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 14897-14902
    • Willecke, M.1    Hamaratoglu, F.2    Sansores-Garcia, L.3    Tao, C.4    Halder, G.5
  • 43
    • 0042232429 scopus 로고    scopus 로고
    • Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
    • DOI 10.1016/S0092-8674(03)00549-X
    • S. Wu, J. Huang, J. Dong, and D. Pan hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts Cell 114 2003 445 456 (Pubitemid 37100993)
    • (2003) Cell , vol.114 , Issue.4 , pp. 445-456
    • Wu, S.1    Huang, J.2    Dong, J.3    Pan, D.4
  • 44
    • 42049116586 scopus 로고    scopus 로고
    • The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
    • S. Wu, Y. Liu, Y. Zheng, J. Dong, and D. Pan The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway Dev. Cell 14 2008 388 398
    • (2008) Dev. Cell , vol.14 , pp. 388-398
    • Wu, S.1    Liu, Y.2    Zheng, Y.3    Dong, J.4    Pan, D.5
  • 46
    • 58749094798 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate regulates glioblastoma cell invasiveness through the urokinase plasminogen activator system and CCN1/Cyr61
    • N. Young, D.K. Pearl, and J.R. Van Brocklyn Sphingosine-1-phosphate regulates glioblastoma cell invasiveness through the urokinase plasminogen activator system and CCN1/Cyr61 Mol. Cancer Res. 7 2009 23 32
    • (2009) Mol. Cancer Res. , vol.7 , pp. 23-32
    • Young, N.1    Pearl, D.K.2    Van Brocklyn, J.R.3
  • 47
    • 42049120338 scopus 로고    scopus 로고
    • The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control
    • L. Zhang, F. Ren, Q. Zhang, Y. Chen, B. Wang, and J. Jiang The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control Dev. Cell 14 2008 377 387
    • (2008) Dev. Cell , vol.14 , pp. 377-387
    • Zhang, L.1    Ren, F.2    Zhang, Q.3    Chen, Y.4    Wang, B.5    Jiang, J.6
  • 48
    • 67649412006 scopus 로고    scopus 로고
    • TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition
    • H. Zhang, C.Y. Liu, Z.Y. Zha, B. Zhao, J. Yao, S. Zhao, Y. Xiong, Q.Y. Lei, and K.L. Guan TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition J. Biol. Chem. 284 2009 13355 13362
    • (2009) J. Biol. Chem. , vol.284 , pp. 13355-13362
    • Zhang, H.1    Liu, C.Y.2    Zha, Z.Y.3    Zhao, B.4    Yao, J.5    Zhao, S.6    Xiong, Y.7    Lei, Q.Y.8    Guan, K.L.9
  • 51
    • 73549095761 scopus 로고    scopus 로고
    • A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
    • B. Zhao, L. Li, K. Tumaneng, C.Y. Wang, and K.L. Guan A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP) Genes Dev. 24 2010 72 85
    • (2010) Genes Dev. , vol.24 , pp. 72-85
    • Zhao, B.1    Li, L.2    Tumaneng, K.3    Wang, C.Y.4    Guan, K.L.5
  • 52
    • 79960997489 scopus 로고    scopus 로고
    • The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
    • B. Zhao, K. Tumaneng, and K.L. Guan The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal Nat. Cell Biol. 13 2011 877 883
    • (2011) Nat. Cell Biol. , vol.13 , pp. 877-883
    • Zhao, B.1    Tumaneng, K.2    Guan, K.L.3
  • 53
    • 78650895035 scopus 로고    scopus 로고
    • Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
    • B. Zhao, L. Li, Q. Lu, L.H. Wang, C.Y. Liu, Q. Lei, and K.L. Guan Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein Genes Dev. 25 2011 51 63
    • (2011) Genes Dev. , vol.25 , pp. 51-63
    • Zhao, B.1    Li, L.2    Lu, Q.3    Wang, L.H.4    Liu, C.Y.5    Lei, Q.6    Guan, K.L.7
  • 54
    • 70350502865 scopus 로고    scopus 로고
    • Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
    • D. Zhou, C. Conrad, F. Xia, J.S. Park, B. Payer, Y. Yin, G.Y. Lauwers, W. Thasler, J.T. Lee, J. Avruch, and N. Bardeesy Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene Cancer Cell 16 2009 425 438
    • (2009) Cancer Cell , vol.16 , pp. 425-438
    • Zhou, D.1    Conrad, C.2    Xia, F.3    Park, J.S.4    Payer, B.5    Yin, Y.6    Lauwers, G.Y.7    Thasler, W.8    Lee, J.T.9    Avruch, J.10    Bardeesy, N.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.