YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 7, 2012, Pages 2394-2399

  Von Gise, Alexander ^a,b   Lin, Zhiqiang ^a   Schlegelmilch, Karin ^a,c,d,e   Honor, Leah B ^a   Pan, Gina M ^a   Buck, Jessica N ^a   Ma, Qing ^a   Ishiwata, Takahiro ^f   Zhou, Bin ^a,g   Camargo, Fernando D ^a,d,e   Pu, William T ^a,f  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d HARVARD UNIVERSITY   (United States)

^e HARVARD STEM CELL INSTITUTE   (United States)

^f UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^g Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Heart development; Physiological hypertrophy

Indexed keywords

HIPPO KINASE; PHOSPHOTRANSFERASE; TRANSCRIPTION FACTOR YAP1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL CYCLE; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; HEART DEVELOPMENT; HEART HYPERTROPHY; HEART MUSCLE CELL; LOSS OF FUNCTION MUTATION; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE REGENERATION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CARDIOMEGALY; GENES, CDC; HEART; MYOCARDIUM; PROTEIN-SERINE-THREONINE KINASES; RATS; SIGNAL TRANSDUCTION;

EID: 84857136357     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1116136109     Document Type: Article

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