Role of TAZ as mediator of wnt signaling

Cell

Volumn 151, Issue 7, 2012, Pages 1443-1456

  Azzolin, Luca ^a   Zanconato, Francesca ^a   Bresolin, Silvia ^b   Forcato, Mattia ^c   Basso, Giuseppe ^b   Bicciato, Silvio ^c   Cordenonsi, Michelangelo ^a   Piccolo, Stefano ^a  

^a UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; AXIN; BETA CATENIN; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3; MESSENGER RNA; PLAKOGLOBIN; SMALL INTERFERING RNA; TAZ PROTEIN; TRANSCRIPTION FACTOR; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; WNT PROTEIN; WNT3A PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HEK293; COLON CANCER; CONTROLLED STUDY; CYTOPLASM; EMBRYONIC STEM CELL; ENZYME INACTIVATION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 84886943235     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2012.11.027     Document Type: Article

References (40)

1. S. Barolo Transgenic Wnt/TCF pathway reporters: all you need is Lef? Oncogene 25 2006 7505 7511
2. A. Ben-Ze'ev The dual role of cytoskeletal anchor proteins in cell adhesion and signal transduction Ann. N Y Acad. Sci. 886 1999 37 47
3. K.P. Bhat, K.L. Salazar, V. Balasubramaniyan, K. Wani, L. Heathcock, F. Hollingsworth, J.D. James, J. Gumin, K.L. Diefes, and S.H. Kim The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma Genes Dev. 25 2011 2594 2609
4. H. Clevers Wnt/β-catenin signaling in development and disease Cell 127 2006 469 480
5. M. Cordenonsi, F. Zanconato, L. Azzolin, M. Forcato, A. Rosato, C. Frasson, M. Inui, M. Montagner, A.R. Parenti, and A. Poletti The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells Cell 147 2011 759 772
6. S. Dupont, L. Morsut, M. Aragona, E. Enzo, S. Giulitti, M. Cordenonsi, F. Zanconato, J. Le Digabel, M. Forcato, and S. Bicciato Role of YAP/TAZ in mechanotransduction Nature 474 2011 179 183
7. M.C. Faux, J.L. Ross, C. Meeker, T. Johns, H. Ji, R.J. Simpson, M.J. Layton, and A.W. Burgess Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion J. Cell Sci. 117 2004 427 439
8. G. Halder, S. Dupont, and S. Piccolo Transduction of mechanical and cytoskeletal cues by YAP and TAZ Nat. Rev. Mol. Cell Biol. 13 2012 591 600
9. J.H. Hong, E.S. Hwang, M.T. McManus, A. Amsterdam, Y. Tian, R. Kalmukova, E. Mueller, T. Benjamin, B.M. Spiegelman, and P.A. Sharp TAZ, a transcriptional modulator of mesenchymal stem cell differentiation Science 309 2005 1074 1078
10. S.M. Huang, Y.M. Mishina, S. Liu, A. Cheung, F. Stegmeier, G.A. Michaud, O. Charlat, E. Wiellette, Y. Zhang, and S. Wiessner Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling Nature 461 2009 614 620
11. W. Huang, X. Lv, C. Liu, Z. Zha, H. Zhang, Y. Jiang, Y. Xiong, Q.Y. Lei, and K.L. Guan The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFβ-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition J. Biol. Chem. 287 2012 26245 26253
12. M. Imajo, K. Miyatake, A. Iimura, A. Miyamoto, and E. Nishida A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling EMBO J. 31 2012 1109 1122
13. N.G. Kim, C. Xu, and B.M. Gumbiner Identification of targets of the Wnt pathway destruction complex in addition to β-catenin Proc. Natl. Acad. Sci. USA 106 2009 5165 5170
14. P. Leucht, S. Minear, D. Ten Berge, R. Nusse, and J.A. Helms Translating insights from development into regenerative medicine: the function of Wnts in bone biology Semin. Cell Dev. Biol. 19 2008 434 443
15. V.S. Li, S.S. Ng, P.J. Boersema, T.Y. Low, W.R. Karthaus, J.P. Gerlach, S. Mohammed, A.J. Heck, M.M. Maurice, T. Mahmoudi, and H. Clevers Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex Cell 149 2012 1245 1256
16. C. Liu, Y. Li, M. Semenov, C. Han, G.H. Baeg, Y. Tan, Z. Zhang, X. Lin, and X. He Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism Cell 108 2002 837 847
17. C.Y. Liu, Z.Y. Zha, X. Zhou, H. Zhang, W. Huang, D. Zhao, T. Li, S.W. Chan, C.J. Lim, and W. Hong The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCFβ-TrCP E3 ligase J. Biol. Chem. 285 2010 37159 37169
18. B.T. MacDonald, K. Tamai, and X. He Wnt/β-catenin signaling: components, mechanisms, and diseases Dev. Cell 17 2009 9 26
19. R. Makita, Y. Uchijima, K. Nishiyama, T. Amano, Q. Chen, T. Takeuchi, A. Mitani, T. Nagase, Y. Yatomi, and H. Aburatani Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ Am. J. Physiol. Renal Physiol. 294 2008 F542 F553
20. R.T. Moon, A.D. Kohn, G.V. De Ferrari, and A. Kaykas WNT and β-catenin signalling: diseases and therapies Nat. Rev. Genet. 5 2004 691 701
21. C. Niehrs, and S.P. Acebron Mitotic and mitogenic Wnt signalling EMBO J. 31 2012 2705 2713
22. N. Nishioka, K. Inoue, K. Adachi, H. Kiyonari, M. Ota, A. Ralston, N. Yabuta, S. Hirahara, R.O. Stephenson, and N. Ogonuki The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass Dev. Cell 16 2009 398 410
23. D. Pan The hippo signaling pathway in development and cancer Dev. Cell 19 2010 491 505
24. A. Ramos, and F.D. Camargo The Hippo signaling pathway and stem cell biology Trends Cell Biol. 22 2012 339 346
25. S.E. Ross, N. Hemati, K.A. Longo, C.N. Bennett, P.C. Lucas, R.L. Erickson, and O.A. MacDougald Inhibition of adipogenesis by Wnt signaling Science 289 2000 950 953
26. C. Scheel, E.N. Eaton, S.H. Li, C.L. Chaffer, F. Reinhardt, K.J. Kah, G. Bell, W. Guo, J. Rubin, A.L. Richardson, and R.A. Weinberg Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast Cell 145 2011 926 940
27. V.F. Taelman, R. Dobrowolski, J.L. Plouhinec, L.C. Fuentealba, P.P. Vorwald, I. Gumper, D.D. Sabatini, and E.M. De Robertis Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes Cell 143 2010 1136 1148
28. M. van de Wetering, E. Sancho, C. Verweij, W. de Lau, I. Oving, A. Hurlstone, K. van der Horn, E. Batlle, D. Coudreuse, and A.P. Haramis The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells Cell 111 2002 241 250
29. X. Varelas, B.W. Miller, R. Sopko, S. Song, A. Gregorieff, F.A. Fellouse, R. Sakuma, T. Pawson, W. Hunziker, and H. McNeill The Hippo pathway regulates Wnt/β-catenin signaling Dev. Cell 18 2010 579 591
30. X. Varelas, P. Samavarchi-Tehrani, M. Narimatsu, A. Weiss, K. Cockburn, B.G. Larsen, J. Rossant, and J.L. Wrana The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway Dev. Cell 19 2010 831 844
31. C. Xu, N.G. Kim, and B.M. Gumbiner Regulation of protein stability by GSK3 mediated phosphorylation Cell Cycle 8 2009 4032 4039
32. B. Zhao, L. Li, K. Tumaneng, C.Y. Wang, and K.L. Guan A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(β-TRCP) Genes Dev. 24 2010 72 85
33. Irizarry, R.A.; Hobbs, B.; Collin, F.; Beazer-Barclay, Y.D.; Antonellis, K.J.; Scherf, U.; and Speed, T.P. (2003). Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4, 249-264.
34. Jin, J.; Ang, X.L.; Shirogane, T.; and Wade Harper, J. (2005). Identification of substrates for F-box proteins. Methods Enzymol. 399, 287-309.
35. Maherali, N.; Ahfeldt, T.; Rigamonti, A.; Utikal, J.; Cowan, C.; and Hochedlinger, K. (2008). A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell 3, 340-345.
36. Maretto, S.; Cordenonsi, M.; Dupont, S.; Braghetta, P.; Broccoli, V.; Hassan, A.B.; Volpin, D.; Bressan, G.M.; and Piccolo, S. (2003). Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc. Natl. Acad. Sci. USA 100, 3299-3304.
37. Martello, G.; Rosato, A.; Ferrari, F.; Manfrin, A.; Cordenonsi, M.; Dupont, S.; Enzo, E.; Guzzardo, V.; Rondina, M.; Spruce, T.; et al. (2010). A MicroRNA targeting dicer for metastasis control. Cell 141, 1195-1207.
38. Morsut, L.; Yan, K.P.; Enzo, E.; Aragona, M.; Soligo, S.M.; Wendling, O.; Mark, M.; Khetchoumian, K.; Bressan, G.; Chambon, P.; et al. (2010). Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo. Development 137, 2571-2578.
39. Sansom, O.J.; Reed, K.R.; Hayes, A.J.; Ireland, H.; Brinkmann, H.; Newton, I.P.; Batlle, E.; Simon-Assmann, P.; Clevers, H.; Nathke, I.S.; et al. (2004). Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. Genes Dev. 18, 1385-1390.
40. Tusher, V.G.; Tibshirani, R.; and Chu, G. (2001). Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98, 5116-5121.