Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 4, 2010, Pages 1431-1436

  Song, Hai ^a   Mak, Kinglun Kingston ^a   Topol, Lilia ^a   Yun, Kangsun ^a   Hu, Jianxin ^a   Garrett, Lisa ^a   Chen, Yongbin ^b   Park, Ogyi ^c   Chang, Jia ^d   Simpson, R Mark ^e   Wang, Cun Yu ^d   Gao, Bin ^c   Jiang, Jin ^b   Yang, Yingzi ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^d UCLA SCHOOL OF DENTISTRY   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Hippo signaling; Tumor suppressor; Yap phosphorylation

Indexed keywords

PROTEIN KINASE; PROTEIN MST1; PROTEIN MST2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; IN VITRO STUDY; IN VIVO STUDY; LETHALITY; LIVER; MOUSE; NONHUMAN; ORGAN SIZE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; STEM CELL;

ANIMALS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEPATOCYTE GROWTH FACTOR; LIVER; LIVER NEOPLASMS; MICE; MUTATION; ORGAN SIZE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

MAMMALIA; MUS; VERTEBRATA;

EID: 76549127712     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0911409107     Document Type: Article

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