메뉴 건너뛰기




Volumn 241, Issue 1, 2012, Pages 3-15

Hippo signaling in Drosophila: Recent advances and insights

Author keywords

Drosophila; Growth; Hippo; Imaginal disc; Signaling; Tumor

Indexed keywords

EXPANDED PROTEIN; F ACTIN; FAT; HIPPO PROTEIN; JUB PROTEIN; LIM PROTEIN; MERLIN; MOB AS TUMOR SUPPRESSOR PROTEIN; PHOSPHOTRANSFERASE; PP2A PHOSPHATASE; PROTEIN SERINE THREONINE KINASE; REGULATOR PROTEIN; SALVADOR PROTEIN; STRIATIN INTERACTING PHOSPHATASE AND KINASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; WARTS PROTEIN; ZYX PROTEIN;

EID: 80755162531     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22723     Document Type: Review
Times cited : (208)

References (136)
  • 2
    • 58049218983 scopus 로고    scopus 로고
    • Tissue damage-induced intestinal stem cell division in Drosophila
    • Amcheslavsky A, Jiang J, Ip YT. 2009. Tissue damage-induced intestinal stem cell division in Drosophila. Cell Stem Cell 4: 49-61.
    • (2009) Cell Stem Cell , vol.4 , pp. 49-61
    • Amcheslavsky, A.1    Jiang, J.2    Ip, Y.T.3
  • 3
    • 61749089153 scopus 로고    scopus 로고
    • The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie
    • Badouel C, Gardano L, Amin N, Garg A, Rosenfeld R, Le Bihan T, McNeill H. 2009. The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie. Dev Cell 16: 411-420.
    • (2009) Dev Cell , vol.16 , pp. 411-420
    • Badouel, C.1    Gardano, L.2    Amin, N.3    Garg, A.4    Rosenfeld, R.5    Le Bihan, T.6    McNeill, H.7
  • 4
    • 47749136645 scopus 로고    scopus 로고
    • The tumor suppressor genes dachsous and fat modulate different signalling pathways by regulating dally and dally-like
    • Baena-Lopez LA, Rodriguez I, Baonza A. 2008. The tumor suppressor genes dachsous and fat modulate different signalling pathways by regulating dally and dally-like. Proc Natl Acad Sci U S A 105: 9645-9650.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 9645-9650
    • Baena-Lopez, L.A.1    Rodriguez, I.2    Baonza, A.3
  • 5
    • 69549096490 scopus 로고    scopus 로고
    • Regulation of leg size and shape by the Dachsous/Fat signalling pathway during regeneration
    • Bando T, Mito T, Maeda Y, Nakamura T, Ito F, Watanabe T, Ohuchi H, Noji S. 2009. Regulation of leg size and shape by the Dachsous/Fat signalling pathway during regeneration. Development 136: 2235-2245.
    • (2009) Development , vol.136 , pp. 2235-2245
    • Bando, T.1    Mito, T.2    Maeda, Y.3    Nakamura, T.4    Ito, F.5    Watanabe, T.6    Ohuchi, H.7    Noji, S.8
  • 7
    • 73549097743 scopus 로고    scopus 로고
    • JAK/STAT signaling coordinates stem cell proliferation and multilineage differentiation in the Drosophila intestinal stem cell lineage
    • Beebe K, Lee W, Micchelli CA. 2009. JAK/STAT signaling coordinates stem cell proliferation and multilineage differentiation in the Drosophila intestinal stem cell lineage. Dev Biol 338: 28-37.
    • (2009) Dev Biol , vol.338 , pp. 28-37
    • Beebe, K.1    Lee, W.2    Micchelli, C.A.3
  • 8
    • 33750611115 scopus 로고    scopus 로고
    • Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway
    • Bennett FC, Harvey KF. 2006. Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway. Curr Biol 16: 2101-2110.
    • (2006) Curr Biol , vol.16 , pp. 2101-2110
    • Bennett, F.C.1    Harvey, K.F.2
  • 9
    • 77649176432 scopus 로고    scopus 로고
    • Imaginal discs: renaissance of a model for regenerative biology
    • Bergantinos C, Vilana X, Corominas M, Serras F. 2010. Imaginal discs: renaissance of a model for regenerative biology. Bioessays 32: 207-217.
    • (2010) Bioessays , vol.32 , pp. 207-217
    • Bergantinos, C.1    Vilana, X.2    Corominas, M.3    Serras, F.4
  • 10
    • 60749112337 scopus 로고    scopus 로고
    • YAP: at the crossroad between transformation and tumor suppression
    • Bertini E, Oka T, Sudol M, Strano S, Blandino G. 2009. YAP: at the crossroad between transformation and tumor suppression. Cell Cycle 8: 49-57.
    • (2009) Cell Cycle , vol.8 , pp. 49-57
    • Bertini, E.1    Oka, T.2    Sudol, M.3    Strano, S.4    Blandino, G.5
  • 11
    • 0034617129 scopus 로고    scopus 로고
    • Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors
    • Bilder D, Li M, Perrimon N. 2000. Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science 289: 113-116.
    • (2000) Science , vol.289 , pp. 113-116
    • Bilder, D.1    Li, M.2    Perrimon, N.3
  • 12
    • 0027291288 scopus 로고
    • Expanded: a gene involved in the control of cell proliferation in imaginal discs
    • Boedigheimer M, Laughon A. 1993. Expanded: a gene involved in the control of cell proliferation in imaginal discs. Development 118: 1291-1301.
    • (1993) Development , vol.118 , pp. 1291-1301
    • Boedigheimer, M.1    Laughon, A.2
  • 13
    • 77953127131 scopus 로고    scopus 로고
    • Four-jointed modulates growth and planar polarity by reducing the affinity of dachsous for fat
    • Brittle AL, Repiso A, Casal J, Lawrence PA, Strutt D. 2010. Four-jointed modulates growth and planar polarity by reducing the affinity of dachsous for fat. Curr Biol 20: 803-810.
    • (2010) Curr Biol , vol.20 , pp. 803-810
    • Brittle, A.L.1    Repiso, A.2    Casal, J.3    Lawrence, P.A.4    Strutt, D.5
  • 14
    • 70349617469 scopus 로고    scopus 로고
    • Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila
    • Buchon N, Broderick NA, Chakrabarti S, Lemaitre B. 2009. Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila. Genes Dev 23: 2333-2344.
    • (2009) Genes Dev , vol.23 , pp. 2333-2344
    • Buchon, N.1    Broderick, N.A.2    Chakrabarti, S.3    Lemaitre, B.4
  • 15
    • 78049451932 scopus 로고    scopus 로고
    • The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program
    • Cai J, Zhang N, Zheng Y, de Wilde RF, Maitra A, Pan D. 2010. The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. Genes Dev 24: 2383-2388.
    • (2010) Genes Dev , vol.24 , pp. 2383-2388
    • Cai, J.1    Zhang, N.2    Zheng, Y.3    de Wilde, R.F.4    Maitra, A.5    Pan, D.6
  • 16
    • 0026573992 scopus 로고
    • The scalloped gene encodes a novel, evolutionarily conserved transcription factor required for sensory organ differentiation in Drosophila
    • Campbell S, Inamdar M, Rodrigues V, Raghavan V, Palazzolo M, Chovnick A. 1992. The scalloped gene encodes a novel, evolutionarily conserved transcription factor required for sensory organ differentiation in Drosophila. Genes Dev 6: 367-379.
    • (1992) Genes Dev , vol.6 , pp. 367-379
    • Campbell, S.1    Inamdar, M.2    Rodrigues, V.3    Raghavan, V.4    Palazzolo, M.5    Chovnick, A.6
  • 18
    • 67650388208 scopus 로고    scopus 로고
    • Pathogenic stimulation of intestinal stem cell response in Drosophila
    • Chatterjee M, Ip YT. 2009. Pathogenic stimulation of intestinal stem cell response in Drosophila. J Cell Physiol 220: 664-671.
    • (2009) J Cell Physiol , vol.220 , pp. 664-671
    • Chatterjee, M.1    Ip, Y.T.2
  • 19
    • 0030858496 scopus 로고    scopus 로고
    • Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands
    • Chen HI, Einbond A, Kwak SJ, Linn H, Koepf E, Peterson S, Kelly JW, Sudol M. 1997. Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands. J Biol Chem 272: 17070-17077.
    • (1997) J Biol Chem , vol.272 , pp. 17070-17077
    • Chen, H.I.1    Einbond, A.2    Kwak, S.J.3    Linn, H.4    Koepf, E.5    Peterson, S.6    Kelly, J.W.7    Sudol, M.8
  • 21
    • 6944253410 scopus 로고    scopus 로고
    • Action of fat, four-jointed, dachsous and dachs in distal-to-proximal wing signaling
    • Cho E, Irvine KD. 2004. Action of fat, four-jointed, dachsous and dachs in distal-to-proximal wing signaling. Development 131: 4489-4500.
    • (2004) Development , vol.131 , pp. 4489-4500
    • Cho, E.1    Irvine, K.D.2
  • 24
    • 33749341786 scopus 로고    scopus 로고
    • WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors
    • Dhananjayan SC, Ramamoorthy S, Khan OY, Ismail A, Sun J, Slingerland J, O'Malley BW, Nawaz Z. 2006. WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors. Mol Endocrinol 20: 2343-2354.
    • (2006) Mol Endocrinol , vol.20 , pp. 2343-2354
    • Dhananjayan, S.C.1    Ramamoorthy, S.2    Khan, O.Y.3    Ismail, A.4    Sun, J.5    Slingerland, J.6    O'Malley, B.W.7    Nawaz, Z.8
  • 26
    • 52949102178 scopus 로고    scopus 로고
    • Apoptosis-induced compensatory proliferation. The cell is dead. Long live the cell!
    • Fan Y, Bergmann A. 2008. Apoptosis-induced compensatory proliferation. The cell is dead. Long live the cell! Trends Cell Biol 18: 467-473.
    • (2008) Trends Cell Biol , vol.18 , pp. 467-473
    • Fan, Y.1    Bergmann, A.2
  • 27
    • 38049103263 scopus 로고    scopus 로고
    • Fat and expanded act in parallel to regulate growth through warts
    • Feng Y, Irvine KD. 2007. Fat and expanded act in parallel to regulate growth through warts. Proc Natl Acad Sci U S A 104: 20362-20367.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 20362-20367
    • Feng, Y.1    Irvine, K.D.2
  • 28
    • 67749093511 scopus 로고    scopus 로고
    • Processing and phosphorylation of the Fat receptor
    • Feng Y, Irvine KD. 2009. Processing and phosphorylation of the Fat receptor. Proc Natl Acad Sci U S A 106: 11989-11994.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 11989-11994
    • Feng, Y.1    Irvine, K.D.2
  • 29
    • 79956327002 scopus 로고    scopus 로고
    • Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
    • Fernandez BG, Gaspar P, Bras-Pereira C, Jezowska B, Rebelo SR, Janody F. 2011. Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila. Development 138: 2337-2346.
    • (2011) Development , vol.138 , pp. 2337-2346
    • Fernandez, B.G.1    Gaspar, P.2    Bras-Pereira, C.3    Jezowska, B.4    Rebelo, S.R.5    Janody, F.6
  • 31
    • 76249093838 scopus 로고    scopus 로고
    • Kibra is a regulator of the Salvador/Warts/Hippo signaling network
    • Genevet A, Wehr MC, Brain R, Thompson BJ, Tapon N. 2010. Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev Cell 18: 300-308.
    • (2010) Dev Cell , vol.18 , pp. 300-308
    • Genevet, A.1    Wehr, M.C.2    Brain, R.3    Thompson, B.J.4    Tapon, N.5
  • 32
    • 79955881075 scopus 로고    scopus 로고
    • A screen for conditional growth suppressor genes identifies the drosophila homolog of HD-PTP as a regulator of the Oncoprotein Yorkie
    • Gilbert MM, Tipping M, Veraksa A, Moberg KH. 2011. A screen for conditional growth suppressor genes identifies the drosophila homolog of HD-PTP as a regulator of the Oncoprotein Yorkie. Dev Cell 20: 700-712.
    • (2011) Dev Cell , vol.20 , pp. 700-712
    • Gilbert, M.M.1    Tipping, M.2    Veraksa, A.3    Moberg, K.H.4
  • 33
    • 78149476036 scopus 로고    scopus 로고
    • The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex
    • Gladden AB, Hebert AM, Schneeberger EE, McClatchey AI. 2010. The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell 19: 727-739.
    • (2010) Dev Cell , vol.19 , pp. 727-739
    • Gladden, A.B.1    Hebert, A.M.2    Schneeberger, E.E.3    McClatchey, A.I.4
  • 34
    • 0037044808 scopus 로고    scopus 로고
    • Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation
    • Glantschnig H, Rodan GA, Reszka AA. 2002. Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation. J Biol Chem 277: 42987-42996.
    • (2002) J Biol Chem , vol.277 , pp. 42987-42996
    • Glantschnig, H.1    Rodan, G.A.2    Reszka, A.A.3
  • 35
    • 40849086201 scopus 로고    scopus 로고
    • SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila
    • Goulev Y, Fauny JD, Gonzalez-Marti B, Flagiello D, Silber J, Zider A. 2008. SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila. Curr Biol 18: 435-441.
    • (2008) Curr Biol , vol.18 , pp. 435-441
    • Goulev, Y.1    Fauny, J.D.2    Gonzalez-Marti, B.3    Flagiello, D.4    Silber, J.5    Zider, A.6
  • 36
    • 77349083312 scopus 로고    scopus 로고
    • Cell Adhesion and Transcriptional Activity - Defining the Role of the Novel Protooncogene LPP
    • Grunewald TG, Pasedag SM, Butt E. 2009. Cell Adhesion and Transcriptional Activity - Defining the Role of the Novel Protooncogene LPP. Transl Oncol 2: 107-116.
    • (2009) Transl Oncol , vol.2 , pp. 107-116
    • Grunewald, T.G.1    Pasedag, S.M.2    Butt, E.3
  • 37
    • 79151476076 scopus 로고    scopus 로고
    • The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster
    • Grusche FA, Degoutin JL, Richardson HE, Harvey KF. 2011. The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster. Dev Biol 350: 255-266.
    • (2011) Dev Biol , vol.350 , pp. 255-266
    • Grusche, F.A.1    Degoutin, J.L.2    Richardson, H.E.3    Harvey, K.F.4
  • 38
    • 35348895013 scopus 로고    scopus 로고
    • Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye
    • Grzeschik NA, Amin N, Secombe J, Brumby AM, Richardson HE. 2007. Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye. Dev Biol 311: 106-123.
    • (2007) Dev Biol , vol.311 , pp. 106-123
    • Grzeschik, N.A.1    Amin, N.2    Secombe, J.3    Brumby, A.M.4    Richardson, H.E.5
  • 39
    • 77950485564 scopus 로고    scopus 로고
    • Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms
    • Grzeschik NA, Parsons LM, Allott ML, Harvey KF, Richardson HE. 2010. Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr Biol 20: 573-581.
    • (2010) Curr Biol , vol.20 , pp. 573-581
    • Grzeschik, N.A.1    Parsons, L.M.2    Allott, M.L.3    Harvey, K.F.4    Richardson, H.E.5
  • 41
    • 78650724753 scopus 로고    scopus 로고
    • Hippo signaling: growth control and beyond
    • Halder G, Johnson RL. 2011. Hippo signaling: growth control and beyond. Development 138: 9-22.
    • (2011) Development , vol.138 , pp. 9-22
    • Halder, G.1    Johnson, R.L.2
  • 42
    • 30344445706 scopus 로고    scopus 로고
    • The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
    • Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C, Jafar-Nejad H, Halder G. 2006. The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat Cell Biol 8: 27-36.
    • (2006) Nat Cell Biol , vol.8 , pp. 27-36
    • Hamaratoglu, F.1    Willecke, M.2    Kango-Singh, M.3    Nolo, R.4    Hyun, E.5    Tao, C.6    Jafar-Nejad, H.7    Halder, G.8
  • 43
    • 0042733354 scopus 로고    scopus 로고
    • The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
    • Harvey KF, Pfleger CM, Hariharan IK. 2003. The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell 114: 457-467.
    • (2003) Cell , vol.114 , pp. 457-467
    • Harvey, K.F.1    Pfleger, C.M.2    Hariharan, I.K.3
  • 44
    • 79953293637 scopus 로고    scopus 로고
    • Zyxin emerges as a key player in the mechanotransduction at cell adhesive structures
    • Hirata H, Tatsumi H, Sokabe M. 2008. Zyxin emerges as a key player in the mechanotransduction at cell adhesive structures. Commun Integr Biol 1: 192-195.
    • (2008) Commun Integr Biol , vol.1 , pp. 192-195
    • Hirata, H.1    Tatsumi, H.2    Sokabe, M.3
  • 46
    • 72649099866 scopus 로고    scopus 로고
    • Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila
    • Ho LL, Wei X, Shimizu T, Lai ZC. 2010. Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila. Dev Biol 337: 274-283.
    • (2010) Dev Biol , vol.337 , pp. 274-283
    • Ho, L.L.1    Wei, X.2    Shimizu, T.3    Lai, Z.C.4
  • 47
    • 23744458034 scopus 로고    scopus 로고
    • The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
    • Huang J, Wu S, Barrera J, Matthews K, Pan D. 2005. The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 122: 421-434.
    • (2005) Cell , vol.122 , pp. 421-434
    • Huang, J.1    Wu, S.2    Barrera, J.3    Matthews, K.4    Pan, D.5
  • 49
    • 68149108277 scopus 로고    scopus 로고
    • Correcting developmental errors by apoptosis: lessons from Drosophila JNK signaling
    • Igaki T. 2009. Correcting developmental errors by apoptosis: lessons from Drosophila JNK signaling. Apoptosis: an international journal on programmed cell death 14: 1021-1028.
    • (2009) Apoptosis: an international journal on programmed cell death , vol.14 , pp. 1021-1028
    • Igaki, T.1
  • 50
    • 47749093500 scopus 로고    scopus 로고
    • Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains
    • Ishikawa HO, Takeuchi H, Haltiwanger RS, Irvine KD. 2008. Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains. Science 321: 401-404.
    • (2008) Science , vol.321 , pp. 401-404
    • Ishikawa, H.O.1    Takeuchi, H.2    Haltiwanger, R.S.3    Irvine, K.D.4
  • 51
    • 33749388932 scopus 로고    scopus 로고
    • Actin capping protein alpha maintains vestigial-expressing cells within the Drosophila wing disc epithelium
    • Janody F, Treisman JE. 2006. Actin capping protein alpha maintains vestigial-expressing cells within the Drosophila wing disc epithelium. Development 133: 3349-3357.
    • (2006) Development , vol.133 , pp. 3349-3357
    • Janody, F.1    Treisman, J.E.2
  • 52
    • 0142123293 scopus 로고    scopus 로고
    • The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
    • Jia J, Zhang W, Wang B, Trinko R, Jiang J. 2003. The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis. Genes Dev 17: 2514-2519.
    • (2003) Genes Dev , vol.17 , pp. 2514-2519
    • Jia, J.1    Zhang, W.2    Wang, B.3    Trinko, R.4    Jiang, J.5
  • 53
    • 67549133157 scopus 로고    scopus 로고
    • Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut
    • Jiang H, Patel PH, Kohlmaier A, Grenley MO, McEwen DG, Edgar BA. 2009. Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut. Cell 137: 1343-1355.
    • (2009) Cell , vol.137 , pp. 1343-1355
    • Jiang, H.1    Patel, P.H.2    Kohlmaier, A.3    Grenley, M.O.4    McEwen, D.G.5    Edgar, B.A.6
  • 54
    • 0028902594 scopus 로고
    • The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
    • Justice RW, Zilian O, Woods DF, Noll M, Bryant PJ. 1995. The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev 9: 534-546.
    • (1995) Genes Dev , vol.9 , pp. 534-546
    • Justice, R.W.1    Zilian, O.2    Woods, D.F.3    Noll, M.4    Bryant, P.J.5
  • 55
    • 67649618708 scopus 로고    scopus 로고
    • Regulation of organ size: insights from the Drosophila Hippo signaling pathway
    • Kango-Singh M, Singh A. 2009. Regulation of organ size: insights from the Drosophila Hippo signaling pathway. Dev Dyn 238: 1627-1637.
    • (2009) Dev Dyn , vol.238 , pp. 1627-1637
    • Kango-Singh, M.1    Singh, A.2
  • 57
    • 78650202455 scopus 로고    scopus 로고
    • The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration
    • Karpowicz P, Perez J, Perrimon N. 2010. The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration. Development 137: 4135-4145.
    • (2010) Development , vol.137 , pp. 4135-4145
    • Karpowicz, P.1    Perez, J.2    Perrimon, N.3
  • 59
    • 0032578033 scopus 로고    scopus 로고
    • Structural analysis of Drosophila merlin reveals functional domains important for growth control and subcellular localization
    • LaJeunesse DR, McCartney BM, Fehon RG. 1998. Structural analysis of Drosophila merlin reveals functional domains important for growth control and subcellular localization. J Cell Biol 141: 1589-1599.
    • (1998) J Cell Biol , vol.141 , pp. 1589-1599
    • LaJeunesse, D.R.1    McCartney, B.M.2    Fehon, R.G.3
  • 60
    • 42049123063 scopus 로고    scopus 로고
    • Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus
    • Langer EM, Feng Y, Zhaoyuan H, Rauscher FJ III, Kroll KL, Longmore GD. 2008. Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus. Dev Cell 14: 424-436.
    • (2008) Dev Cell , vol.14 , pp. 424-436
    • Langer, E.M.1    Feng, Y.2    Zhaoyuan, H.3    Rauscher III, F.J.4    Kroll, K.L.5    Longmore, G.D.6
  • 61
    • 0037023722 scopus 로고    scopus 로고
    • Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST)
    • Lee KK, Yonehara S. 2002. Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST). J Biol Chem 277: 12351-12358.
    • (2002) J Biol Chem , vol.277 , pp. 12351-12358
    • Lee, K.K.1    Yonehara, S.2
  • 62
    • 77953738883 scopus 로고    scopus 로고
    • The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
    • Ling C, Zheng Y, Yin F, Yu J, Huang J, Hong Y, Wu S, Pan D. 2010. The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci U S A 107: 10532-10537.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 10532-10537
    • Ling, C.1    Zheng, Y.2    Yin, F.3    Yu, J.4    Huang, J.5    Hong, Y.6    Wu, S.7    Pan, D.8
  • 63
    • 0034671858 scopus 로고    scopus 로고
    • Roles for scalloped and vestigial in regulating cell affinity and interactions between the wing blade and the wing hinge
    • Liu X, Grammont M, Irvine KD. 2000. Roles for scalloped and vestigial in regulating cell affinity and interactions between the wing blade and the wing hinge. Dev Biol 228: 287-303.
    • (2000) Dev Biol , vol.228 , pp. 287-303
    • Liu, X.1    Grammont, M.2    Irvine, K.D.3
  • 64
    • 28544438939 scopus 로고    scopus 로고
    • Endocytic control of epithelial polarity and proliferation in Drosophila
    • Lu H, Bilder D. 2005. Endocytic control of epithelial polarity and proliferation in Drosophila. Nat Cell Biol 7: 1232-1239.
    • (2005) Nat Cell Biol , vol.7 , pp. 1232-1239
    • Lu, H.1    Bilder, D.2
  • 65
    • 0025748166 scopus 로고
    • The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily
    • Mahoney PA, Weber U, Onofrechuk P, Biessmann H, Bryant PJ, Goodman CS. 1991. The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily. Cell 67: 853-868.
    • (1991) Cell , vol.67 , pp. 853-868
    • Mahoney, P.A.1    Weber, U.2    Onofrechuk, P.3    Biessmann, H.4    Bryant, P.J.5    Goodman, C.S.6
  • 66
    • 33645868635 scopus 로고    scopus 로고
    • The tumor suppressors Merlin and expanded function cooperatively to modulate receptor endocytosis and signaling
    • Maitra S, Kulikauskas RM, Gavilan H, Fehon RG. 2006. The tumor suppressors Merlin and expanded function cooperatively to modulate receptor endocytosis and signaling. Curr Biol 16: 702-709.
    • (2006) Curr Biol , vol.16 , pp. 702-709
    • Maitra, S.1    Kulikauskas, R.M.2    Gavilan, H.3    Fehon, R.G.4
  • 67
    • 0032940071 scopus 로고    scopus 로고
    • ERM proteins in cell adhesion and membrane dynamics
    • Mangeat P, Roy C, Martin M. 1999. ERM proteins in cell adhesion and membrane dynamics. Trends Cell Biol 9: 187-192.
    • (1999) Trends Cell Biol , vol.9 , pp. 187-192
    • Mangeat, P.1    Roy, C.2    Martin, M.3
  • 68
    • 33746410714 scopus 로고    scopus 로고
    • Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila
    • Mao Y, Rauskolb C, Cho E, Hu WL, Hayter H, Minihan G, Katz FN, Irvine KD. 2006. Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila. Development 133: 2539-2551.
    • (2006) Development , vol.133 , pp. 2539-2551
    • Mao, Y.1    Rauskolb, C.2    Cho, E.3    Hu, W.L.4    Hayter, H.5    Minihan, G.6    Katz, F.N.7    Irvine, K.D.8
  • 69
    • 70349912183 scopus 로고    scopus 로고
    • Drosophila lowfat, a novel modulator of Fat signaling
    • Mao Y, Kucuk B, Irvine KD. 2009. Drosophila lowfat, a novel modulator of Fat signaling. Development 136: 3223-3233.
    • (2009) Development , vol.136 , pp. 3223-3233
    • Mao, Y.1    Kucuk, B.2    Irvine, K.D.3
  • 71
    • 4444240972 scopus 로고    scopus 로고
    • Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing
    • Matakatsu H, Blair SS. 2004. Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing. Development 131: 3785-3794.
    • (2004) Development , vol.131 , pp. 3785-3794
    • Matakatsu, H.1    Blair, S.S.2
  • 72
    • 33745899356 scopus 로고    scopus 로고
    • Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins
    • Matakatsu H, Blair SS. 2006. Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins. Development 133: 2315-2324.
    • (2006) Development , vol.133 , pp. 2315-2324
    • Matakatsu, H.1    Blair, S.S.2
  • 73
    • 52049093202 scopus 로고    scopus 로고
    • The DHHC palmitoyltransferase approximated regulates Fat signaling and Dachs localization and activity
    • Matakatsu H, Blair SS. 2008. The DHHC palmitoyltransferase approximated regulates Fat signaling and Dachs localization and activity. Curr Biol 18: 1390-1395.
    • (2008) Curr Biol , vol.18 , pp. 1390-1395
    • Matakatsu, H.1    Blair, S.S.2
  • 74
    • 0034033896 scopus 로고    scopus 로고
    • The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation
    • McCartney BM, Kulikauskas RM, LaJeunesse DR, Fehon RG. 2000. The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation. Development 127: 1315-1324.
    • (2000) Development , vol.127 , pp. 1315-1324
    • McCartney, B.M.1    Kulikauskas, R.M.2    LaJeunesse, D.R.3    Fehon, R.G.4
  • 75
    • 35548970323 scopus 로고    scopus 로고
    • The salvador-warts-hippo pathway is required for epithelial proliferation and axis specification in Drosophila
    • Meignin C, Alvarez-Garcia I, Davis I, Palacios IM. 2007. The salvador-warts-hippo pathway is required for epithelial proliferation and axis specification in Drosophila. Curr Biol 17: 1871-1878.
    • (2007) Curr Biol , vol.17 , pp. 1871-1878
    • Meignin, C.1    Alvarez-Garcia, I.2    Davis, I.3    Palacios, I.M.4
  • 76
    • 77955971943 scopus 로고    scopus 로고
    • A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway
    • Menendez J, Perez-Garijo A, Calleja M, Morata G. 2010. A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway. Proc Natl Acad Sci U S A 107: 14651-14656.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14651-14656
    • Menendez, J.1    Perez-Garijo, A.2    Calleja, M.3    Morata, G.4
  • 77
    • 31444452338 scopus 로고    scopus 로고
    • Evidence that stem cells reside in the adult Drosophila midgut epithelium
    • Micchelli CA, Perrimon N. 2006. Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature 439: 475-479.
    • (2006) Nature , vol.439 , pp. 475-479
    • Micchelli, C.A.1    Perrimon, N.2
  • 79
    • 76449118721 scopus 로고    scopus 로고
    • Differential requirement of Salvador-Warts-Hippo pathway members for organ size control in Drosophila melanogaster
    • Milton CC, Zhang X, Albanese NO, Harvey KF. 2010. Differential requirement of Salvador-Warts-Hippo pathway members for organ size control in Drosophila melanogaster. Development 137: 735-743.
    • (2010) Development , vol.137 , pp. 735-743
    • Milton, C.C.1    Zhang, X.2    Albanese, N.O.3    Harvey, K.F.4
  • 80
    • 77957881882 scopus 로고    scopus 로고
    • Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap
    • Neto-Silva RM, de Beco S, Johnston LA. 2010. Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap. Dev Cell 19: 507-520.
    • (2010) Dev Cell , vol.19 , pp. 507-520
    • Neto-Silva, R.M.1    de Beco, S.2    Johnston, L.A.3
  • 81
    • 79951692812 scopus 로고    scopus 로고
    • Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit
    • Nicolay BN, Bayarmagnai B, Islam AB, Lopez-Bigas N, Frolov MV. 2011. Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit. Genes Dev 25: 323-335.
    • (2011) Genes Dev , vol.25 , pp. 323-335
    • Nicolay, B.N.1    Bayarmagnai, B.2    Islam, A.B.3    Lopez-Bigas, N.4    Frolov, M.V.5
  • 82
    • 33749242966 scopus 로고    scopus 로고
    • The bantam microRNA is a target of the hippo tumor-suppressor pathway
    • Nolo R, Morrison CM, Tao C, Zhang X, Halder G. 2006. The bantam microRNA is a target of the hippo tumor-suppressor pathway. Curr Biol 16: 1895-1904.
    • (2006) Curr Biol , vol.16 , pp. 1895-1904
    • Nolo, R.1    Morrison, C.M.2    Tao, C.3    Zhang, X.4    Halder, G.5
  • 83
    • 42549092233 scopus 로고    scopus 로고
    • In vivo regulation of Yorkie phosphorylation and localization
    • Oh H, Irvine KD. 2008. In vivo regulation of Yorkie phosphorylation and localization. Development 135: 1081-1088.
    • (2008) Development , vol.135 , pp. 1081-1088
    • Oh, H.1    Irvine, K.D.2
  • 84
    • 67349136817 scopus 로고    scopus 로고
    • In vivo analysis of Yorkie phosphorylation sites
    • Oh H, Irvine KD. 2009. In vivo analysis of Yorkie phosphorylation sites. Oncogene 28: 1916-1927.
    • (2009) Oncogene , vol.28 , pp. 1916-1927
    • Oh, H.1    Irvine, K.D.2
  • 85
    • 77954313699 scopus 로고    scopus 로고
    • Yorkie: the final destination of Hippo signaling
    • Oh H, Irvine KD. 2010. Yorkie: the final destination of Hippo signaling. Trends Cell Biol 20: 410-417.
    • (2010) Trends Cell Biol , vol.20 , pp. 410-417
    • Oh, H.1    Irvine, K.D.2
  • 86
    • 78651421847 scopus 로고    scopus 로고
    • Cooperative regulation of growth by Yorkie and Mad through bantam
    • Oh H, Irvine KD. 2011. Cooperative regulation of growth by Yorkie and Mad through bantam. Dev Cell 20: 109-122.
    • (2011) Dev Cell , vol.20 , pp. 109-122
    • Oh, H.1    Irvine, K.D.2
  • 87
    • 70349786516 scopus 로고    scopus 로고
    • Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling
    • Oh H, Reddy BV, Irvine KD. 2009. Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling. Dev Biol 335: 188-197.
    • (2009) Dev Biol , vol.335 , pp. 188-197
    • Oh, H.1    Reddy, B.V.2    Irvine, K.D.3
  • 88
    • 31444444485 scopus 로고    scopus 로고
    • The adult Drosophila posterior midgut is maintained by pluripotent stem cells
    • Ohlstein B, Spradling A. 2006. The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature 439: 470-474.
    • (2006) Nature , vol.439 , pp. 470-474
    • Ohlstein, B.1    Spradling, A.2
  • 89
    • 77957883342 scopus 로고    scopus 로고
    • The hippo signaling pathway in development and cancer
    • Pan D. 2010. The hippo signaling pathway in development and cancer. Dev Cell 19: 491-505.
    • (2010) Dev Cell , vol.19 , pp. 491-505
    • Pan, D.1
  • 90
    • 0141505119 scopus 로고    scopus 로고
    • The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
    • Pantalacci S, Tapon N, Leopold P. 2003. The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila. Nat Cell Biol 5: 921-927.
    • (2003) Nat Cell Biol , vol.5 , pp. 921-927
    • Pantalacci, S.1    Tapon, N.2    Leopold, P.3
  • 91
    • 70349624119 scopus 로고    scopus 로고
    • Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc
    • Peng HW, Slattery M, Mann RS. 2009. Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc. Genes Dev 23: 2307-2319.
    • (2009) Genes Dev , vol.23 , pp. 2307-2319
    • Peng, H.W.1    Slattery, M.2    Mann, R.S.3
  • 92
    • 35548957838 scopus 로고    scopus 로고
    • Salvador-warts-hippo signaling promotes Drosophila posterior follicle cell maturation downstream of notch
    • Polesello C, Tapon N. 2007. Salvador-warts-hippo signaling promotes Drosophila posterior follicle cell maturation downstream of notch. Curr Biol 17: 1864-1870.
    • (2007) Curr Biol , vol.17 , pp. 1864-1870
    • Polesello, C.1    Tapon, N.2
  • 93
    • 33845426464 scopus 로고    scopus 로고
    • The Drosophila RASSF homolog antagonizes the hippo pathway
    • Polesello C, Huelsmann S, Brown NH, Tapon N. 2006. The Drosophila RASSF homolog antagonizes the hippo pathway. Curr Biol 16: 2459-2465.
    • (2006) Curr Biol , vol.16 , pp. 2459-2465
    • Polesello, C.1    Huelsmann, S.2    Brown, N.H.3    Tapon, N.4
  • 95
    • 48749118705 scopus 로고    scopus 로고
    • The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation
    • Reddy BV, Irvine KD. 2008. The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation. Development 135: 2827-2838.
    • (2008) Development , vol.135 , pp. 2827-2838
    • Reddy, B.V.1    Irvine, K.D.2
  • 96
    • 77954636475 scopus 로고    scopus 로고
    • Influence of fat-hippo and notch signaling on the proliferation and differentiation of Drosophila optic neuroepithelia
    • Reddy BV, Rauskolb C, Irvine KD. 2010. Influence of fat-hippo and notch signaling on the proliferation and differentiation of Drosophila optic neuroepithelia. Development 137: 2397-2408.
    • (2010) Development , vol.137 , pp. 2397-2408
    • Reddy, B.V.1    Rauskolb, C.2    Irvine, K.D.3
  • 97
    • 78650471357 scopus 로고    scopus 로고
    • Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways
    • Ren F, Wang B, Yue T, Yun EY, Ip YT, Jiang J. 2010a. Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways. Proc Natl Acad Sci U S A 107: 21064-21069.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 21064-21069
    • Ren, F.1    Wang, B.2    Yue, T.3    Yun, E.Y.4    Ip, Y.T.5    Jiang, J.6
  • 98
    • 72649088969 scopus 로고    scopus 로고
    • Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms
    • Ren F, Zhang L, Jiang J. 2010b. Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms. Dev Biol 337: 303-312.
    • (2010) Dev Biol , vol.337 , pp. 303-312
    • Ren, F.1    Zhang, L.2    Jiang, J.3
  • 99
    • 77955988806 scopus 로고    scopus 로고
    • Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling
    • Ribeiro PS, Josue F, Wepf A, Wehr MC, Rinner O, Kelly G, Tapon N, Gstaiger M. 2010. Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling. Mol Cell 39: 521-534.
    • (2010) Mol Cell , vol.39 , pp. 521-534
    • Ribeiro, P.S.1    Josue, F.2    Wepf, A.3    Wehr, M.C.4    Rinner, O.5    Kelly, G.6    Tapon, N.7    Gstaiger, M.8
  • 100
    • 77950478873 scopus 로고    scopus 로고
    • Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded
    • Robinson BS, Huang J, Hong Y, Moberg KH. 2010. Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr Biol 20: 582-590.
    • (2010) Curr Biol , vol.20 , pp. 582-590
    • Robinson, B.S.1    Huang, J.2    Hong, Y.3    Moberg, K.H.4
  • 101
    • 48749101754 scopus 로고    scopus 로고
    • Morphogen control of wing growth through the Fat signaling pathway
    • Rogulja D, Rauskolb C, Irvine KD. 2008. Morphogen control of wing growth through the Fat signaling pathway. Dev Cell 15: 309-321.
    • (2008) Dev Cell , vol.15 , pp. 309-321
    • Rogulja, D.1    Rauskolb, C.2    Irvine, K.D.3
  • 104
    • 78650187792 scopus 로고    scopus 로고
    • The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration
    • Shaw RL, Kohlmaier A, Polesello C, Veelken C, Edgar BA, Tapon N. 2010. The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration. Development 137: 4147-4158.
    • (2010) Development , vol.137 , pp. 4147-4158
    • Shaw, R.L.1    Kohlmaier, A.2    Polesello, C.3    Veelken, C.4    Edgar, B.A.5    Tapon, N.6
  • 105
    • 33750624298 scopus 로고    scopus 로고
    • The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway
    • Silva E, Tsatskis Y, Gardano L, Tapon N, McNeill H. 2006. The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway. Curr Biol 16: 2081-2089.
    • (2006) Curr Biol , vol.16 , pp. 2081-2089
    • Silva, E.1    Tsatskis, Y.2    Gardano, L.3    Tapon, N.4    McNeill, H.5
  • 106
    • 77953324959 scopus 로고    scopus 로고
    • Modulation of Fat:Dachsous binding by the cadherin domain kinase four-jointed
    • Simon MA, Xu A, Ishikawa HO, Irvine KD. 2010. Modulation of Fat:Dachsous binding by the cadherin domain kinase four-jointed. Curr Biol 20: 811-817.
    • (2010) Curr Biol , vol.20 , pp. 811-817
    • Simon, M.A.1    Xu, A.2    Ishikawa, H.O.3    Irvine, K.D.4
  • 108
    • 77956507262 scopus 로고    scopus 로고
    • Warts and Yorkie mediate intestinal regeneration by influencing stem cell proliferation
    • Staley BK, Irvine KD. 2010. Warts and Yorkie mediate intestinal regeneration by influencing stem cell proliferation. Curr Biol 20: 1580-1587.
    • (2010) Curr Biol , vol.20 , pp. 1580-1587
    • Staley, B.K.1    Irvine, K.D.2
  • 109
    • 78651261751 scopus 로고    scopus 로고
    • Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors
    • Sun G, Irvine KD. 2011. Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors. Dev Biol 350: 139-151.
    • (2011) Dev Biol , vol.350 , pp. 139-151
    • Sun, G.1    Irvine, K.D.2
  • 110
    • 0037162714 scopus 로고    scopus 로고
    • salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
    • Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber DA, Hariharan IK. 2002. salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110: 467-478.
    • (2002) Cell , vol.110 , pp. 467-478
    • Tapon, N.1    Harvey, K.F.2    Bell, D.W.3    Wahrer, D.C.4    Schiripo, T.A.5    Haber, D.A.6    Hariharan, I.K.7
  • 111
    • 0025285657 scopus 로고
    • crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia
    • Tepass U, Theres C, Knust E. 1990. crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia. Cell 61: 787-799.
    • (1990) Cell , vol.61 , pp. 787-799
    • Tepass, U.1    Theres, C.2    Knust, E.3
  • 112
    • 33747159113 scopus 로고    scopus 로고
    • The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila
    • Thompson BJ, Cohen SM. 2006. The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell 126: 767-774.
    • (2006) Cell , vol.126 , pp. 767-774
    • Thompson, B.J.1    Cohen, S.M.2
  • 113
    • 34247134640 scopus 로고    scopus 로고
    • Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways
    • Tyler DM, Baker NE. 2007. Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways. Dev Biol 305: 187-201.
    • (2007) Dev Biol , vol.305 , pp. 187-201
    • Tyler, D.M.1    Baker, N.E.2
  • 114
    • 0141616617 scopus 로고    scopus 로고
    • Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
    • Udan RS, Kango-Singh M, Nolo R, Tao C, Halder G. 2003. Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway. Nat Cell Biol 5: 914-920.
    • (2003) Nat Cell Biol , vol.5 , pp. 914-920
    • Udan, R.S.1    Kango-Singh, M.2    Nolo, R.3    Tao, C.4    Halder, G.5
  • 116
    • 0037441865 scopus 로고    scopus 로고
    • Zyxin and paxillin proteins: focal adhesion plaque LIM domain proteins go nuclear
    • Wang Y, Gilmore TD. 2003. Zyxin and paxillin proteins: focal adhesion plaque LIM domain proteins go nuclear. Biochim Biophys Acta 1593: 115-120.
    • (2003) Biochim Biophys Acta , vol.1593 , pp. 115-120
    • Wang, Y.1    Gilmore, T.D.2
  • 117
    • 65249102236 scopus 로고    scopus 로고
    • YAP, TAZ, and Yorkie: a conserved family of signal-responsive transcriptional coregulators in animal development and human disease
    • Wang K, Degerny C, Xu M, Yang XJ. 2009. YAP, TAZ, and Yorkie: a conserved family of signal-responsive transcriptional coregulators in animal development and human disease. Biochem Cell Biol 87: 77-91.
    • (2009) Biochem Cell Biol , vol.87 , pp. 77-91
    • Wang, K.1    Degerny, C.2    Xu, M.3    Yang, X.J.4
  • 118
    • 0028707914 scopus 로고
    • Drosophila in cancer research: the first fifty tumor suppressor genes
    • Watson KL, Justice RW, Bryant PJ. 1994. Drosophila in cancer research: the first fifty tumor suppressor genes. J Cell Sci Suppl 18: 19-33.
    • (1994) J Cell Sci Suppl , vol.18 , pp. 19-33
    • Watson, K.L.1    Justice, R.W.2    Bryant, P.J.3
  • 119
    • 34247182696 scopus 로고    scopus 로고
    • Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
    • Wei X, Shimizu T, Lai ZC. 2007. Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila. EMBO J 26: 1772-1781.
    • (2007) EMBO J , vol.26 , pp. 1772-1781
    • Wei, X.1    Shimizu, T.2    Lai, Z.C.3
  • 121
    • 54449090287 scopus 로고    scopus 로고
    • Boundaries of Dachsous Cadherin activity modulate the Hippo signaling pathway to induce cell proliferation
    • Willecke M, Hamaratoglu F, Sansores-Garcia L, Tao C, Halder G. 2008. Boundaries of Dachsous Cadherin activity modulate the Hippo signaling pathway to induce cell proliferation. Proc Natl Acad Sci U S A 105: 14897-14902.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14897-14902
    • Willecke, M.1    Hamaratoglu, F.2    Sansores-Garcia, L.3    Tao, C.4    Halder, G.5
  • 122
    • 0042232429 scopus 로고    scopus 로고
    • hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
    • Wu S, Huang J, Dong J, Pan D. 2003. hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell 114: 445-456.
    • (2003) Cell , vol.114 , pp. 445-456
    • Wu, S.1    Huang, J.2    Dong, J.3    Pan, D.4
  • 123
    • 42049116586 scopus 로고    scopus 로고
    • The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
    • Wu S, Liu Y, Zheng Y, Dong J, Pan D. 2008. The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev Cell 14: 388-398.
    • (2008) Dev Cell , vol.14 , pp. 388-398
    • Wu, S.1    Liu, Y.2    Zheng, Y.3    Dong, J.4    Pan, D.5
  • 124
    • 0028929414 scopus 로고
    • Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase
    • Xu T, Wang W, Zhang S, Stewart RA, Yu W. 1995. Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development 121: 1053-1063.
    • (1995) Development , vol.121 , pp. 1053-1063
    • Xu, T.1    Wang, W.2    Zhang, S.3    Stewart, R.A.4    Yu, W.5
  • 125
    • 79955427372 scopus 로고    scopus 로고
    • Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling
    • Yan Y, Denef N, Tang C, Schupbach T. 2011. Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling. Development 138: 1697-1703.
    • (2011) Development , vol.138 , pp. 1697-1703
    • Yan, Y.1    Denef, N.2    Tang, C.3    Schupbach, T.4
  • 126
    • 46149099112 scopus 로고    scopus 로고
    • The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity
    • Yu J, Poulton J, Huang YC, Deng WM. 2008. The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity. PLoS One 3: e1761.
    • (2008) PLoS One , vol.3
    • Yu, J.1    Poulton, J.2    Huang, Y.C.3    Deng, W.M.4
  • 127
    • 76249109900 scopus 로고    scopus 로고
    • Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
    • Yu J, Zheng Y, Dong J, Klusza S, Deng WM, Pan D. 2010. Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev Cell 18: 288-299.
    • (2010) Dev Cell , vol.18 , pp. 288-299
    • Yu, J.1    Zheng, Y.2    Dong, J.3    Klusza, S.4    Deng, W.M.5    Pan, D.6
  • 128
    • 77954740913 scopus 로고    scopus 로고
    • A feed-forward circuit linking wingless, fat-dachsous signaling, and the warts-hippo pathway to Drosophila wing growth
    • Zecca M, Struhl G. 2010. A feed-forward circuit linking wingless, fat-dachsous signaling, and the warts-hippo pathway to Drosophila wing growth. PLoS Biol 8: e1000386.
    • (2010) PLoS Biol , vol.8
    • Zecca, M.1    Struhl, G.2
  • 129
    • 42049120338 scopus 로고    scopus 로고
    • The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control
    • Zhang L, Ren F, Zhang Q, Chen Y, Wang B, Jiang J. 2008. The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev Cell 14: 377-387.
    • (2008) Dev Cell , vol.14 , pp. 377-387
    • Zhang, L.1    Ren, F.2    Zhang, Q.3    Chen, Y.4    Wang, B.5    Jiang, J.6
  • 131
    • 68049142436 scopus 로고    scopus 로고
    • Transcriptional output of the Salvador/warts/hippo pathway is controlled in distinct fashions in Drosophila melanogaster and mammalian cell lines
    • Zhang X, Milton CC, Humbert PO, Harvey KF. 2009b. Transcriptional output of the Salvador/warts/hippo pathway is controlled in distinct fashions in Drosophila melanogaster and mammalian cell lines. Cancer Res 69: 6033-6041.
    • (2009) Cancer Res , vol.69 , pp. 6033-6041
    • Zhang, X.1    Milton, C.C.2    Humbert, P.O.3    Harvey, K.F.4
  • 132
    • 79960216886 scopus 로고    scopus 로고
    • Wbp2 cooperates with Yorkie to drive tissue growth downstream of the Salvador-Warts-Hippo pathway
    • Zhang X, Milton CC, Poon CL, Hong W, Harvey KF. 2011. Wbp2 cooperates with Yorkie to drive tissue growth downstream of the Salvador-Warts-Hippo pathway. Cell Death Differ 18: 1346-1355.
    • (2011) Cell Death Differ , vol.18 , pp. 1346-1355
    • Zhang, X.1    Milton, C.C.2    Poon, C.L.3    Hong, W.4    Harvey, K.F.5
  • 134
    • 45849146998 scopus 로고    scopus 로고
    • Basolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cells
    • Zhao M, Szafranski P, Hall CA, Goode S. 2008. Basolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cells. Genetics 178: 1947-1971.
    • (2008) Genetics , vol.178 , pp. 1947-1971
    • Zhao, M.1    Szafranski, P.2    Hall, C.A.3    Goode, S.4
  • 135
    • 77951837150 scopus 로고    scopus 로고
    • The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
    • Zhao B, Li L, Lei Q, Guan KL. 2010. The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev 24: 862-874.
    • (2010) Genes Dev , vol.24 , pp. 862-874
    • Zhao, B.1    Li, L.2    Lei, Q.3    Guan, K.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.