-
1
-
-
0242585476
-
Asymmetric inheritance of oxidatively damaged proteins during cytokinesis
-
Aguilaniu H., Gustafsson L., Rigoulet M., and Nystrom T. Asymmetric inheritance of oxidatively damaged proteins during cytokinesis. Science 299 (2003) 1751-1753
-
(2003)
Science
, vol.299
, pp. 1751-1753
-
-
Aguilaniu, H.1
Gustafsson, L.2
Rigoulet, M.3
Nystrom, T.4
-
2
-
-
0345731468
-
Yeast life-span extension by calorie restriction is independent of NAD fluctuation
-
Anderson R.M., Latorre-Esteves M., Neves A.R., Lavu S., Medvedik O., Taylor C., Howitz K.T., Santos H., and Sinclair D.A. Yeast life-span extension by calorie restriction is independent of NAD fluctuation. Science 302 (2003) 2124-2126
-
(2003)
Science
, vol.302
, pp. 2124-2126
-
-
Anderson, R.M.1
Latorre-Esteves, M.2
Neves, A.R.3
Lavu, S.4
Medvedik, O.5
Taylor, C.6
Howitz, K.T.7
Santos, H.8
Sinclair, D.A.9
-
3
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
Araki T., Sasaki Y., and Milbrandt J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305 (2004) 1010-1013
-
(2004)
Science
, vol.305
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
4
-
-
33744976074
-
C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend lifespan
-
Berdichevsky A., Viswanathan M., Horvitz H.R., and Guarente L. C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend lifespan. Cell 125 (2006) 1165-1177
-
(2006)
Cell
, vol.125
, pp. 1165-1177
-
-
Berdichevsky, A.1
Viswanathan, M.2
Horvitz, H.R.3
Guarente, L.4
-
5
-
-
0037160097
-
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1
-
Bitterman K.J., Anderson R.M., Cohen H.Y., Latorre-Esteves M., and Sinclair D.A. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J. Biol. Chem. 277 (2002) 45099-45107
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45099-45107
-
-
Bitterman, K.J.1
Anderson, R.M.2
Cohen, H.Y.3
Latorre-Esteves, M.4
Sinclair, D.A.5
-
6
-
-
0141677687
-
Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatin
-
Bitterman K.J., Medvedik O., and Sinclair D.A. Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatin. Microbiol. Mol. Biol. Rev. 67 (2003) 376-399
-
(2003)
Microbiol. Mol. Biol. Rev.
, vol.67
, pp. 376-399
-
-
Bitterman, K.J.1
Medvedik, O.2
Sinclair, D.A.3
-
7
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
Blander G., and Guarente L. The Sir2 family of protein deacetylases. Annu. Rev. Biochem. 73 (2004) 417-435
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
8
-
-
0037942739
-
Extended longevity in mice lacking the insulin receptor in adipose tissue
-
Bluher M., Kahn B.B., and Kahn R.C. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299 (2003) 572-574
-
(2003)
Science
, vol.299
, pp. 572-574
-
-
Bluher, M.1
Kahn, B.B.2
Kahn, R.C.3
-
9
-
-
33244486764
-
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells
-
10.1371/journal.pbio.0040031
-
Bordone L., Motta M.C., Picard F., Robinson A., Jhala U.S., Apfeld J., McDonagh T., Lemieux M., McBurney M., Szilvasi A., et al. Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells. PLoS Biol. 4 (2006) e31 10.1371/journal.pbio.0040031
-
(2006)
PLoS Biol.
, vol.4
-
-
Bordone, L.1
Motta, M.C.2
Picard, F.3
Robinson, A.4
Jhala, U.S.5
Apfeld, J.6
McDonagh, T.7
Lemieux, M.8
McBurney, M.9
Szilvasi, A.10
-
10
-
-
20444444649
-
Mechanism of human SIRT1 activation by resveratrol
-
Borra M.T., Smith B.C., and Denu J.M. Mechanism of human SIRT1 activation by resveratrol. J. Biol. Chem. 280 (2005) 17187-17195
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17187-17195
-
-
Borra, M.T.1
Smith, B.C.2
Denu, J.M.3
-
11
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A., Bonni A., Zigmond M.J., Lin M.Z., Juo P., Hu L.S., Anderson M.J., Arden K.C., Blenis J., and Greenberg M.E. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96 (1999) 857-868
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
12
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A., Sweeney L.B., Sturgill J.F., Chua K.F., Greer P.L., Lin Y., Tran H., Ross S.E., Mostoslavsky R., Cohen H.Y., et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303 (2004) 2011-2015
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
-
13
-
-
28844469898
-
Increase in activity during calorie restriction requires Sirt1
-
Chen D., Steele A.D., Lindquist S., and Guarente L. Increase in activity during calorie restriction requires Sirt1. Science 310 (2005) 1641
-
(2005)
Science
, vol.310
, pp. 1641
-
-
Chen, D.1
Steele, A.D.2
Lindquist, S.3
Guarente, L.4
-
14
-
-
28844474597
-
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling
-
Chen J., Zhou Y., Mueller-Steiner S., Chen L.F., Kwon H., Yi S., Mucke L., and Gan L. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. J. Biol. Chem. 280 (2005) 40364-40374
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40364-40374
-
-
Chen, J.1
Zhou, Y.2
Mueller-Steiner, S.3
Chen, L.F.4
Kwon, H.5
Yi, S.6
Mucke, L.7
Gan, L.8
-
15
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
Cheng H.L., Mostoslavsky R., Saito S., Manis J.P., Gu Y., Patel P., Bronson R., Appella E., Alt F.W., and Chua K.F. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc. Natl. Acad. Sci. USA 100 (2003) 10794-10799
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10794-10799
-
-
Cheng, H.L.1
Mostoslavsky, R.2
Saito, S.3
Manis, J.P.4
Gu, Y.5
Patel, P.6
Bronson, R.7
Appella, E.8
Alt, F.W.9
Chua, K.F.10
-
16
-
-
27244435939
-
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress
-
Chua K.F., Mostoslavsky R., Lombard D.B., Pang W.W., Saito S., Franco S., Kaushal D., Cheng H.L., Fischer M.R., Stokes N., et al. Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress. Cell Metab. 2 (2005) 67-76
-
(2005)
Cell Metab.
, vol.2
, pp. 67-76
-
-
Chua, K.F.1
Mostoslavsky, R.2
Lombard, D.B.3
Pang, W.W.4
Saito, S.5
Franco, S.6
Kaushal, D.7
Cheng, H.L.8
Fischer, M.R.9
Stokes, N.10
-
17
-
-
0037066518
-
Dietary restriction in long-lived dwarf flies
-
Clancy D.J., Gems D., Hafen E., Leevers S.J., and Partridge L. Dietary restriction in long-lived dwarf flies. Science 296 (2002) 319
-
(2002)
Science
, vol.296
, pp. 319
-
-
Clancy, D.J.1
Gems, D.2
Hafen, E.3
Leevers, S.J.4
Partridge, L.5
-
18
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen H.Y., Miller C., Bitterman K.J., Wall N.R., Hekking B., Kessler B., Howitz K.T., Gorospe M., de Cabo R., and Sinclair D.A. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305 (2004) 390-392
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
de Cabo, R.9
Sinclair, D.A.10
-
19
-
-
0033120871
-
Elimination of replication block protein Fob1 extends the life span of yeast mother cells
-
Defossez P.A., Prusty R., Kaeberlein M., Lin S.J., Ferrigno P., Silver P.A., Keil R.L., and Guarente L. Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol. Cell 3 (1999) 447-455
-
(1999)
Mol. Cell
, vol.3
, pp. 447-455
-
-
Defossez, P.A.1
Prusty, R.2
Kaeberlein, M.3
Lin, S.J.4
Ferrigno, P.5
Silver, P.A.6
Keil, R.L.7
Guarente, L.8
-
20
-
-
0037221445
-
Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases
-
Denu J.M. Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases. Trends Biochem. Sci. 28 (2003) 41-48
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 41-48
-
-
Denu, J.M.1
-
21
-
-
0035853552
-
Regulation of longevity and stress resistance by Sch9 in yeast
-
Fabrizio P., Pozza F., Pletcher S.D., Gendron C.M., and Longo V.D. Regulation of longevity and stress resistance by Sch9 in yeast. Science 292 (2001) 288-290
-
(2001)
Science
, vol.292
, pp. 288-290
-
-
Fabrizio, P.1
Pozza, F.2
Pletcher, S.D.3
Gendron, C.M.4
Longo, V.D.5
-
22
-
-
0037280096
-
SOD2 functions downstream of Sch9 to extend longevity in yeast
-
Fabrizio P., Liou L.L., Moy V.N., Diaspro A., SelverstoneValentine J., Gralla E.B., and Longo V.D. SOD2 functions downstream of Sch9 to extend longevity in yeast. Genetics 163 (2003) 35-46
-
(2003)
Genetics
, vol.163
, pp. 35-46
-
-
Fabrizio, P.1
Liou, L.L.2
Moy, V.N.3
Diaspro, A.4
SelverstoneValentine, J.5
Gralla, E.B.6
Longo, V.D.7
-
23
-
-
4644342867
-
Superoxide is a mediator of an altruistic aging program in Saccharomyces cerevisiae
-
Fabrizio P., Battistella L., Vardavas R., Gattazzo C., Liou L.L., Diaspro A., Dossen J.W., Gralla E.B., and Longo V.D. Superoxide is a mediator of an altruistic aging program in Saccharomyces cerevisiae. J. Cell Biol. 166 (2004) 1055-1067
-
(2004)
J. Cell Biol.
, vol.166
, pp. 1055-1067
-
-
Fabrizio, P.1
Battistella, L.2
Vardavas, R.3
Gattazzo, C.4
Liou, L.L.5
Diaspro, A.6
Dossen, J.W.7
Gralla, E.B.8
Longo, V.D.9
-
24
-
-
1642491749
-
Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae
-
Fabrizio P., Pletcher S.D., Minois N., Vaupel J.W., and Longo V.D. Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae. FEBS Lett. 557 (2004) 136-142
-
(2004)
FEBS Lett.
, vol.557
, pp. 136-142
-
-
Fabrizio, P.1
Pletcher, S.D.2
Minois, N.3
Vaupel, J.W.4
Longo, V.D.5
-
25
-
-
27744596999
-
Sir2 blocks extreme life-span extension
-
Fabrizio P., Gattazzo C., Battistella L., Wei M., Cheng C., McGrew K., and Longo V.D. Sir2 blocks extreme life-span extension. Cell 123 (2005) 655-667
-
(2005)
Cell
, vol.123
, pp. 655-667
-
-
Fabrizio, P.1
Gattazzo, C.2
Battistella, L.3
Wei, M.4
Cheng, C.5
McGrew, K.6
Longo, V.D.7
-
26
-
-
28544444366
-
Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival
-
Ford J., Jiang M., and Milner J. Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival. Cancer Res. 65 (2005) 10457-10463
-
(2005)
Cancer Res.
, vol.65
, pp. 10457-10463
-
-
Ford, J.1
Jiang, M.2
Milner, J.3
-
27
-
-
0037067696
-
Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family
-
Gao L., Cueto M.A., Asselbergs F., and Atadja P. Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family. J. Biol. Chem. 277 (2002) 25748-25755
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25748-25755
-
-
Gao, L.1
Cueto, M.A.2
Asselbergs, F.3
Atadja, P.4
-
28
-
-
0036021375
-
Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation
-
Garigan D., Hsu A.L., Fraser A.G., Kamath R.S., Ahringer J., and Kenyon C. Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics 161 (2002) 1101-1112
-
(2002)
Genetics
, vol.161
, pp. 1101-1112
-
-
Garigan, D.1
Hsu, A.L.2
Fraser, A.G.3
Kamath, R.S.4
Ahringer, J.5
Kenyon, C.6
-
29
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
Greer E.L., and Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24 (2005) 7410-7425
-
(2005)
Oncogene
, vol.24
, pp. 7410-7425
-
-
Greer, E.L.1
Brunet, A.2
-
30
-
-
2942731801
-
Dynamics of the p53 acetylation pathway
-
discussion 205-197, 223-195
-
Gu W., Luo J., Brooks C.L., Nikolaev A.Y., and Li M. Dynamics of the p53 acetylation pathway. Novartis Found. Symp. 259 (2004) 197-205 discussion 205-197, 223-195
-
(2004)
Novartis Found. Symp.
, vol.259
, pp. 197-205
-
-
Gu, W.1
Luo, J.2
Brooks, C.L.3
Nikolaev, A.Y.4
Li, M.5
-
31
-
-
22744444561
-
Calorie restriction and SIR2 genes-Towards a mechanism
-
Guarente L. Calorie restriction and SIR2 genes-Towards a mechanism. Mech. Ageing Dev. 126 (2005) 923-928
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 923-928
-
-
Guarente, L.1
-
32
-
-
13944253348
-
Calorie restriction-the SIR2 connection
-
Guarente L., and Picard F. Calorie restriction-the SIR2 connection. Cell 120 (2005) 473-482
-
(2005)
Cell
, vol.120
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
33
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz K.T., Bitterman K.J., Cohen H.Y., Lamming D.W., Lavu S., Wood J.G., Zipkin R.E., Chung P., Kisielewski A., Zhang L.L., et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425 (2003) 191-196
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
-
34
-
-
0037965571
-
Telomeric position effect variegation in Saccharomyces cerevisiae by Caenorhabditis elegans linker histones suggests a mechanistic connection between germ line and telomeric silencing
-
Jedrusik M.A., and Schulze E. Telomeric position effect variegation in Saccharomyces cerevisiae by Caenorhabditis elegans linker histones suggests a mechanistic connection between germ line and telomeric silencing. Mol. Cell. Biol. 23 (2003) 3681-3691
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3681-3691
-
-
Jedrusik, M.A.1
Schulze, E.2
-
35
-
-
0036696982
-
Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast
-
Jiang J.C., Wawryn J., Shantha Kumara H.M., and Jazwinski S.M. Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast. Exp. Gerontol. 37 (2002) 1023-1030
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 1023-1030
-
-
Jiang, J.C.1
Wawryn, J.2
Shantha Kumara, H.M.3
Jazwinski, S.M.4
-
36
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
Kaeberlein M., McVey M., and Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13 (1999) 2570-2580
-
(1999)
Genes Dev.
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
37
-
-
19344374925
-
Sir2-independent life span extension by calorie restriction in yeast
-
10.1371/journal.pbio.0020296
-
Kaeberlein M., Kirkland K.T., Fields S., and Kennedy B.K. Sir2-independent life span extension by calorie restriction in yeast. PLoS Biol. 2 (2004) e296 10.1371/journal.pbio.0020296
-
(2004)
PLoS Biol.
, vol.2
-
-
Kaeberlein, M.1
Kirkland, K.T.2
Fields, S.3
Kennedy, B.K.4
-
38
-
-
29244489494
-
Increased life span due to calorie restriction in respiratory deficient yeast
-
10.1371/journal.pgen.0010069
-
Kaeberlein M., Hu D., Kerr E.O., Tsuchiya M., Westman E.A., Dang N., Fields S., and Kennedy B.K. Increased life span due to calorie restriction in respiratory deficient yeast. PLoS Genet 1 (2005) e69 10.1371/journal.pgen.0010069
-
(2005)
PLoS Genet
, vol.1
-
-
Kaeberlein, M.1
Hu, D.2
Kerr, E.O.3
Tsuchiya, M.4
Westman, E.A.5
Dang, N.6
Fields, S.7
Kennedy, B.K.8
-
39
-
-
13944255453
-
Genes determining yeast replicative life span in a long-lived genetic background
-
Kaeberlein M., Kirkland K.T., Fields S., and Kennedy B.K. Genes determining yeast replicative life span in a long-lived genetic background. Mech. Ageing Dev. 126 (2005) 491-504
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 491-504
-
-
Kaeberlein, M.1
Kirkland, K.T.2
Fields, S.3
Kennedy, B.K.4
-
40
-
-
20444431507
-
Substrate specific activation of sirtuins by resveratrol
-
Kaeberlein M., McDonagh T., Heltweg B., Hixon J., Westman E.A., Caldwell S., Napper A., Curtis R., Distefano P.S., Fields S., et al. Substrate specific activation of sirtuins by resveratrol. J. Biol. Chem. 280 (2005) 17038-17045
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17038-17045
-
-
Kaeberlein, M.1
McDonagh, T.2
Heltweg, B.3
Hixon, J.4
Westman, E.A.5
Caldwell, S.6
Napper, A.7
Curtis, R.8
Distefano, P.S.9
Fields, S.10
-
41
-
-
27744511769
-
Regulation of yeast replicative life-span by TOR and Sch9 in response to nutrients
-
Kaeberlein M., Powers III R.W., Steffen K.K., Westman E.A., Hu D., Dang N., Kerr E.O., Kirkland K.T., Fields S., and Kennedy B.K. Regulation of yeast replicative life-span by TOR and Sch9 in response to nutrients. Science 310 (2005) 1193-1196
-
(2005)
Science
, vol.310
, pp. 1193-1196
-
-
Kaeberlein, M.1
Powers III, R.W.2
Steffen, K.K.3
Westman, E.A.4
Hu, D.5
Dang, N.6
Kerr, E.O.7
Kirkland, K.T.8
Fields, S.9
Kennedy, B.K.10
-
42
-
-
33645753014
-
Author's reply
-
10.1371/journal.pgen.0020034
-
Kaeberlein M., Hu D., Kerr E.O., Tsuchiya M., Westman E.A., Dang N., Fields S., and Kennedy B.K. Author's reply. PLoS Genet. 2 (2006) e34 10.1371/journal.pgen.0020034
-
(2006)
PLoS Genet.
, vol.2
-
-
Kaeberlein, M.1
Hu, D.2
Kerr, E.O.3
Tsuchiya, M.4
Westman, E.A.5
Dang, N.6
Fields, S.7
Kennedy, B.K.8
-
43
-
-
33745131114
-
Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction"
-
Kaeberlein M., Steffen K.K., Hu D., Dang N., Kerr E.O., Tsuchiya M., Fields S., and Kennedy B.K. Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". Science 312 (2006) 1312b
-
(2006)
Science
, vol.312
-
-
Kaeberlein, M.1
Steffen, K.K.2
Hu, D.3
Dang, N.4
Kerr, E.O.5
Tsuchiya, M.6
Fields, S.7
Kennedy, B.K.8
-
44
-
-
33644812461
-
SirT1 fails to affect p53-mediated biological functions
-
Kamel C., Abrol M., Jardine K., He X., and McBurney M.W. SirT1 fails to affect p53-mediated biological functions. Aging Cell 5 (2006) 81-88
-
(2006)
Aging Cell
, vol.5
, pp. 81-88
-
-
Kamel, C.1
Abrol, M.2
Jardine, K.3
He, X.4
McBurney, M.W.5
-
45
-
-
0028897013
-
Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae
-
Kennedy B.K., Austriaco N.R., Zhang J., and Guarente L. Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell 80 (1995) 485-496
-
(1995)
Cell
, vol.80
, pp. 485-496
-
-
Kennedy, B.K.1
Austriaco, N.R.2
Zhang, J.3
Guarente, L.4
-
46
-
-
0030916153
-
Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae
-
Kennedy B.K., Gotta M., Sinclair D.A., Mills K., McNabb D.S., Murthy M., Pak S.M., Laroche T., Gasser S.M., and Guarente L. Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. Cell 89 (1997) 381-391
-
(1997)
Cell
, vol.89
, pp. 381-391
-
-
Kennedy, B.K.1
Gotta, M.2
Sinclair, D.A.3
Mills, K.4
McNabb, D.S.5
Murthy, M.6
Pak, S.M.7
Laroche, T.8
Gasser, S.M.9
Guarente, L.10
-
47
-
-
27744554550
-
The enigmatic role of Sir2 in aging
-
Kennedy B.K., Smith E.D., and Kaeberlein M. The enigmatic role of Sir2 in aging. Cell 123 (2005) 548-550
-
(2005)
Cell
, vol.123
, pp. 548-550
-
-
Kennedy, B.K.1
Smith, E.D.2
Kaeberlein, M.3
-
48
-
-
13944269223
-
The plasticity of aging: insights from long-lived mutants
-
Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell 120 (2005) 449-460
-
(2005)
Cell
, vol.120
, pp. 449-460
-
-
Kenyon, C.1
-
49
-
-
0030133624
-
A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities
-
Kobayashi T., and Horiuchi T. A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities. Genes Cells 1 (1996) 465-474
-
(1996)
Genes Cells
, vol.1
, pp. 465-474
-
-
Kobayashi, T.1
Horiuchi, T.2
-
50
-
-
0032573178
-
The genetics of caloric restriction in Caenorhabditis elegans
-
Lakowski B., and Hekimi S. The genetics of caloric restriction in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 95 (1998) 13091-13096
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13091-13096
-
-
Lakowski, B.1
Hekimi, S.2
-
51
-
-
24944559665
-
HST2 mediates SIR2-independent life-span extension by calorie restriction
-
Lamming D.W., Latorre-Esteves M., Medvedik O., Wong S.N., Tsang F.A., Wang C., Lin S.J., and Sinclair D.A. HST2 mediates SIR2-independent life-span extension by calorie restriction. Science 309 (2005) 1861-1864
-
(2005)
Science
, vol.309
, pp. 1861-1864
-
-
Lamming, D.W.1
Latorre-Esteves, M.2
Medvedik, O.3
Wong, S.N.4
Tsang, F.A.5
Wang, C.6
Lin, S.J.7
Sinclair, D.A.8
-
52
-
-
33745131114
-
Response to comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction"
-
Lamming D.W., Latorre-Esteves M., Medvedik O., Wong S.N., Tsang F.A., Wang C., Lin S.-J., and Sinclair D.A. Response to comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". Science 312 (2006) 1312c
-
(2006)
Science
, vol.312
-
-
Lamming, D.W.1
Latorre-Esteves, M.2
Medvedik, O.3
Wong, S.N.4
Tsang, F.A.5
Wang, C.6
Lin, S.-J.7
Sinclair, D.A.8
-
53
-
-
0037093346
-
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
-
Langley E., Pearson M., Faretta M., Bauer U.M., Frye R.A., Minucci S., Pelicci P.G., and Kouzarides T. Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J. 21 (2002) 2383-2396
-
(2002)
EMBO J.
, vol.21
, pp. 2383-2396
-
-
Langley, E.1
Pearson, M.2
Faretta, M.3
Bauer, U.M.4
Frye, R.A.5
Minucci, S.6
Pelicci, P.G.7
Kouzarides, T.8
-
54
-
-
0033565609
-
Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths
-
Lee S.E., Paques F., Sylvan J., and Haber J.E. Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths. Curr. Biol. 9 (1999) 767-770
-
(1999)
Curr. Biol.
, vol.9
, pp. 767-770
-
-
Lee, S.E.1
Paques, F.2
Sylvan, J.3
Haber, J.E.4
-
55
-
-
33646133889
-
Nicotinamide extends the replicative life span of primary human cells
-
Lim C.S., Potts M., and Helm R.F. Nicotinamide extends the replicative life span of primary human cells. Mech. Ageing Dev. 127 (2006) 511-514
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 511-514
-
-
Lim, C.S.1
Potts, M.2
Helm, R.F.3
-
56
-
-
33645774382
-
Increased life span due to calorie restriction in respiratory-deficient yeast
-
10.1371/journal.pgen.0020033
-
Lin S.J., and Guarente L. Increased life span due to calorie restriction in respiratory-deficient yeast. PLoS Genet 2 (2006) e33 10.1371/journal.pgen.0020033
-
(2006)
PLoS Genet
, vol.2
-
-
Lin, S.J.1
Guarente, L.2
-
57
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin S.J., Defossez P.A., and Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289 (2000) 2126-2128
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
58
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
-
Lin S.J., Kaeberlein M., Andalis A.A., Sturtz L.A., Defossez P.A., Culotta V.C., Fink G.R., and Guarente L. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418 (2002) 344-348
-
(2002)
Nature
, vol.418
, pp. 344-348
-
-
Lin, S.J.1
Kaeberlein, M.2
Andalis, A.A.3
Sturtz, L.A.4
Defossez, P.A.5
Culotta, V.C.6
Fink, G.R.7
Guarente, L.8
-
59
-
-
0347128279
-
Calorie restriction extends yeast life span by lowering the level of NADH
-
Lin S.J., Ford E., Haigis M., Liszt G., and Guarente L. Calorie restriction extends yeast life span by lowering the level of NADH. Genes Dev. 18 (2004) 12-16
-
(2004)
Genes Dev.
, vol.18
, pp. 12-16
-
-
Lin, S.J.1
Ford, E.2
Haigis, M.3
Liszt, G.4
Guarente, L.5
-
60
-
-
20444409132
-
Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase
-
Liszt G., Ford E., Kurtev M., and Guarente L. Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase. J. Biol. Chem. 280 (2005) 21313-21320
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 21313-21320
-
-
Liszt, G.1
Ford, E.2
Kurtev, M.3
Guarente, L.4
-
61
-
-
0037470488
-
Evolutionary medicine: from dwarf model systems to healthy centenarians?
-
Longo V.D., and Finch C.E. Evolutionary medicine: from dwarf model systems to healthy centenarians?. Science 299 (2003) 1342-1346
-
(2003)
Science
, vol.299
, pp. 1342-1346
-
-
Longo, V.D.1
Finch, C.E.2
-
62
-
-
0031009829
-
Human Bcl-2 reverses survival defects in yeast lacking superoxide dismutase and delays death of wild-type yeast
-
Longo V.D., Ellerby L.M., Bredesen D.E., Valentine J.S., and Gralla E.B. Human Bcl-2 reverses survival defects in yeast lacking superoxide dismutase and delays death of wild-type yeast. J. Cell Biol. 137 (1997) 1581-1588
-
(1997)
J. Cell Biol.
, vol.137
, pp. 1581-1588
-
-
Longo, V.D.1
Ellerby, L.M.2
Bredesen, D.E.3
Valentine, J.S.4
Gralla, E.B.5
-
63
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo J., Nikolaev A.Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., and Gu W. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107 (2001) 137-148
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
64
-
-
0037207475
-
The mammalian SIR2α protein has a role in embryogenesis and gametogenesis
-
McBurney M.W., Yang X., Jardine K., Hixon M., Boekelheide K., Webb J.R., Lansdorp P.M., and Lemieux M. The mammalian SIR2α protein has a role in embryogenesis and gametogenesis. Mol. Cell. Biol. 23 (2003) 38-54
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 38-54
-
-
McBurney, M.W.1
Yang, X.2
Jardine, K.3
Hixon, M.4
Boekelheide, K.5
Webb, J.R.6
Lansdorp, P.M.7
Lemieux, M.8
-
65
-
-
0004760134
-
Life span of individual yeast cells
-
Mortimer R.K., and Johnston J.R. Life span of individual yeast cells. Nature 183 (1959) 1751-1752
-
(1959)
Nature
, vol.183
, pp. 1751-1752
-
-
Mortimer, R.K.1
Johnston, J.R.2
-
66
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
Mostoslavsky R., Chua K.F., Lombard D.B., Pang W.W., Fischer M.R., Gellon L., Liu P., Mostoslavsky G., Franco S., Murphy M.M., et al. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 124 (2006) 315-329
-
(2006)
Cell
, vol.124
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
-
67
-
-
25144454432
-
Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice
-
Moynihan K.A., Grimm A.A., Plueger M.M., Bernal-Mizrachi E., Ford E., Cras-Meneur C., Permutt M.A., and Imai S. Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice. Cell Metab. 2 (2005) 105-117
-
(2005)
Cell Metab.
, vol.2
, pp. 105-117
-
-
Moynihan, K.A.1
Grimm, A.A.2
Plueger, M.M.3
Bernal-Mizrachi, E.4
Ford, E.5
Cras-Meneur, C.6
Permutt, M.A.7
Imai, S.8
-
68
-
-
0036959009
-
A Drosophila homologue of Sir2 modifies position-effect variegation but does not affect life span
-
Newman B.L., Lundblad J.R., Chen Y., and Smolik S.M. A Drosophila homologue of Sir2 modifies position-effect variegation but does not affect life span. Genetics 162 (2002) 1675-1685
-
(2002)
Genetics
, vol.162
, pp. 1675-1685
-
-
Newman, B.L.1
Lundblad, J.R.2
Chen, Y.3
Smolik, S.M.4
-
69
-
-
30544445468
-
Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells
-
Ota H., Tokunaga E., Chang K., Hikasa M., Iijima K., Eto M., Kozaki K., Akishita M., Ouchi Y., and Kaneki M. Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells. Oncogene 25 (2006) 176-185
-
(2006)
Oncogene
, vol.25
, pp. 176-185
-
-
Ota, H.1
Tokunaga, E.2
Chang, K.3
Hikasa, M.4
Iijima, K.5
Eto, M.6
Kozaki, K.7
Akishita, M.8
Ouchi, Y.9
Kaneki, M.10
-
70
-
-
16844375290
-
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
-
Parker J.A., Arango M., Abderrahmane S., Lambert E., Tourette C., Catoire H., and Neri C. Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. Nat. Genet. 37 (2005) 349-350
-
(2005)
Nat. Genet.
, vol.37
, pp. 349-350
-
-
Parker, J.A.1
Arango, M.2
Abderrahmane, S.3
Lambert, E.4
Tourette, C.5
Catoire, H.6
Neri, C.7
-
71
-
-
0035863153
-
A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast
-
Perrod S., Cockell M.M., Laroche T., Renauld H., Ducrest A.L., Bonnard C., and Gasser S.M. A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. EMBO J. 20 (2001) 197-209
-
(2001)
EMBO J.
, vol.20
, pp. 197-209
-
-
Perrod, S.1
Cockell, M.M.2
Laroche, T.3
Renauld, H.4
Ducrest, A.L.5
Bonnard, C.6
Gasser, S.M.7
-
72
-
-
3042681042
-
SirT1 promotes fat mobilization in white adipocytes by repressing PPARγ
-
Picard F., Kurtev M., Chung N., Topark-Ngarm A., Senawong T., Machado De Oliveira R., Leid M., McBurney M.W., and Guarente L. SirT1 promotes fat mobilization in white adipocytes by repressing PPARγ. Nature 429 (2004) 771-776
-
(2004)
Nature
, vol.429
, pp. 771-776
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
Machado De Oliveira, R.6
Leid, M.7
McBurney, M.W.8
Guarente, L.9
-
73
-
-
30944458446
-
Extension of chronological life span in yeast by decreased TOR pathway signaling
-
Powers III R.W., Kaeberlein M., Caldwell S.D., Kennedy B.K., and Fields S. Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes Dev. 20 (2006) 174-184
-
(2006)
Genes Dev.
, vol.20
, pp. 174-184
-
-
Powers III, R.W.1
Kaeberlein, M.2
Caldwell, S.D.3
Kennedy, B.K.4
Fields, S.5
-
74
-
-
33645768490
-
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation
-
10.1371/journal.pgen.0020040
-
Pruitt K., Zinn R.L., Ohm J.E., McGarvey K.M., Kang S.H., Watkins D.N., Herman J.G., and Baylin S.B. Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet 2 (2006) e40 10.1371/journal.pgen.0020040
-
(2006)
PLoS Genet
, vol.2
-
-
Pruitt, K.1
Zinn, R.L.2
Ohm, J.E.3
McGarvey, K.M.4
Kang, S.H.5
Watkins, D.N.6
Herman, J.G.7
Baylin, S.B.8
-
75
-
-
8544285097
-
SCH9, a putative protein kinase from Saccharomyces cerevisiae, affects HOT1-stimulated recombination
-
Prusty R., and Keil R.L. SCH9, a putative protein kinase from Saccharomyces cerevisiae, affects HOT1-stimulated recombination. Mol. Genet. Genomics 272 (2004) 264-274
-
(2004)
Mol. Genet. Genomics
, vol.272
, pp. 264-274
-
-
Prusty, R.1
Keil, R.L.2
-
76
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers J.T., Lerin C., Haas W., Gygi S.P., Spiegelman B.M., and Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434 (2005) 113-118
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
77
-
-
8644224064
-
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
-
Rogina B., and Helfand S.L. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl. Acad. Sci. USA 101 (2004) 15998-16003
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15998-16003
-
-
Rogina, B.1
Helfand, S.L.2
-
78
-
-
18744416824
-
Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction
-
Rogina B., Helfand S.L., and Frankel S. Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction. Science 298 (2002) 1745
-
(2002)
Science
, vol.298
, pp. 1745
-
-
Rogina, B.1
Helfand, S.L.2
Frankel, S.3
-
79
-
-
0037123765
-
Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(Spl) bHLH repressors in segmentation and sex determination
-
Rosenberg M.I., and Parkhurst S.M. Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(Spl) bHLH repressors in segmentation and sex determination. Cell 109 (2002) 447-458
-
(2002)
Cell
, vol.109
, pp. 447-458
-
-
Rosenberg, M.I.1
Parkhurst, S.M.2
-
81
-
-
0037636027
-
The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae
-
Rusche L.N., Kirchmaier A.L., and Rine J. The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae. Annu. Rev. Biochem. 72 (2003) 481-516
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 481-516
-
-
Rusche, L.N.1
Kirchmaier, A.L.2
Rine, J.3
-
82
-
-
13844252820
-
Regulation of histone deacetylase activities
-
Sengupta N., and Seto E. Regulation of histone deacetylase activities. J. Cell. Biochem. 93 (2004) 57-67
-
(2004)
J. Cell. Biochem.
, vol.93
, pp. 57-67
-
-
Sengupta, N.1
Seto, E.2
-
83
-
-
17144424946
-
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
-
Shi T., Wang F., Stieren E., and Tong Q. SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J. Biol. Chem. 280 (2005) 13560-13567
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 13560-13567
-
-
Shi, T.1
Wang, F.2
Stieren, E.3
Tong, Q.4
-
84
-
-
0031459980
-
Extrachromosomal rDNA circles-a cause of aging in yeast
-
Sinclair D.A., and Guarente L. Extrachromosomal rDNA circles-a cause of aging in yeast. Cell 91 (1997) 1033-1042
-
(1997)
Cell
, vol.91
, pp. 1033-1042
-
-
Sinclair, D.A.1
Guarente, L.2
-
85
-
-
33645221885
-
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage
-
Solomon J.M., Pasupuleti R., Xu L., McDonagh T., Curtis R., DiStefano P.S., and Huber L.J. Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Mol. Cell. Biol. 26 (2006) 28-38
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 28-38
-
-
Solomon, J.M.1
Pasupuleti, R.2
Xu, L.3
McDonagh, T.4
Curtis, R.5
DiStefano, P.S.6
Huber, L.J.7
-
86
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum H.A., and Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410 (2001) 227-230
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
87
-
-
0035913903
-
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H., Dessain S.K., Eaton E.N., Imai S.I., Frye R.A., Pandita T.K., Guarente L., and Weinberg R.A. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107 (2001) 149-159
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
88
-
-
27644585190
-
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span
-
Viswanathan M., Kim S.K., Berdichevsky A., and Guarente L. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Dev. Cell 9 (2005) 605-615
-
(2005)
Dev. Cell
, vol.9
, pp. 605-615
-
-
Viswanathan, M.1
Kim, S.K.2
Berdichevsky, A.3
Guarente, L.4
-
89
-
-
13944269026
-
Dietary restriction in C. elegans: from rate-of-living effects to nutrient sensing pathways
-
Walker G., Houthoofd K., Vanfleteren J.R., and Gems D. Dietary restriction in C. elegans: from rate-of-living effects to nutrient sensing pathways. Mech. Ageing Dev. 126 (2005) 929-937
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 929-937
-
-
Walker, G.1
Houthoofd, K.2
Vanfleteren, J.R.3
Gems, D.4
-
90
-
-
28244475950
-
Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO
-
Wang Y., and Tissenbaum H.A. Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO. Mech. Ageing Dev. 127 (2006) 48-56
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 48-56
-
-
Wang, Y.1
Tissenbaum, H.A.2
-
91
-
-
23744474976
-
A local mechanism mediates NAD-dependent protection of axon degeneration
-
Wang J., Zhai Q., Chen Y., Lin E., Gu W., McBurney M.W., and He Z. A local mechanism mediates NAD-dependent protection of axon degeneration. J. Cell Biol. 170 (2005) 349-355
-
(2005)
J. Cell Biol.
, vol.170
, pp. 349-355
-
-
Wang, J.1
Zhai, Q.2
Chen, Y.3
Lin, E.4
Gu, W.5
McBurney, M.W.6
He, Z.7
-
92
-
-
33746245679
-
C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO
-
10.1016/j.mad.2006.05.005
-
Wang Y., Oh S.W., Deplancke B., Luo J., Walhout A.J.M., and Tissenbaum H.A. C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO. Mech. Ageing Dev. (2006) 10.1016/j.mad.2006.05.005
-
(2006)
Mech. Ageing Dev.
-
-
Wang, Y.1
Oh, S.W.2
Deplancke, B.3
Luo, J.4
Walhout, A.J.M.5
Tissenbaum, H.A.6
-
93
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood J.G., Rogina B., Lavu S., Howitz K., Helfand S.L., Tatar M., and Sinclair D. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430 (2004) 686-689
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.L.5
Tatar, M.6
Sinclair, D.7
-
94
-
-
3242719545
-
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F., Hoberg J.E., Ramsey C.S., Keller M.D., Jones D.R., Frye R.A., and Mayo M.W. Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23 (2004) 2369-2380
-
(2004)
EMBO J.
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
|