The uniqueness of the trypanosoma cruzi mitochondrion: Opportunities to target new drugs against chagaś disease

Current Pharmaceutical Design

Volumn 17, Issue 20, 2011, Pages 2074-2099

  Paes, Lisvane Silva ^a   Mantilla, Brian Suárez ^a   Barisón, María Julia ^a   Wrenger, Carsten ^a   Silber, Ariel Mariano ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Bioenergetics; Chemotherapy; Metabolism; Mitochondria; Oxidative stress; Trypanosoma cruzi

Indexed keywords

3 (3,5 DIBROMO 4 HYDROXYBENZYLIDENE) 1,3 DIHYDRO 5 IODO 2 INDOLONE; ACETYL COENZYME A; ALLOPURINOL; ANTIPROTOZOAL AGENT; BENZNIDAZOLE; CAMPTOTHECIN; COUMAMYCIN A1; CYSTEINE PROTEINASE; DIMINAZENE ACETURATE; DNA TOPOISOMERASE; GLUCOSE; HYDROXYSTILBAMIDINE; ISOPRENOID; METAL COMPLEX; MITOXANTRONE; NAPHTHALENE; NF 023; NIFURTIMOX; PHENYLALANINE; POLYAMINE; POLYISOPRENOID DERIVATIVE; PROLINE; PROPYLPYPERAZINIL DERIVATIVE; PROTOPORPHYRIN; PYRROLE DERIVATIVE; REBECCAMYCIN; SPHINGOSINE; SUCCINIC ACID; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINYL SULPHONE DERIVATIZED DIPEPTIDE;

ADULT; AMINO ACID METABOLISM; ARTICLE; BIOENERGY; CASE REPORT; CHAGAS DISEASE; CITRIC ACID CYCLE; DNA REPLICATION; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG TARGETING; ELECTRON TRANSPORT; GENE EXPRESSION; GENE STRUCTURE; GENETIC TRANSCRIPTION; GLYCOSOME; HUMAN; KINETOPLASTIDA; MITOCHONDRIAL GENOME; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; NUCLEOTIDE METABOLISM; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA EDITING; STEROL SYNTHESIS; TRYPANOSOMA CRUZI;

ANTIPARASITIC AGENTS; CHAGAS DISEASE; HUMANS; MITOCHONDRIA; MOLECULAR TARGETED THERAPY; TRYPANOSOMA CRUZI;

EID: 80052190548     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161211796904786     Document Type: Article

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