Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: A potential route to chemotherapy

Journal of Medicinal Chemistry

Volumn 44, Issue 6, 2001, Pages 909-916

  Martin, M B ^a   Grimley, J S ^a   Lewis, J C ^a   Heath III, H T ^a   Bailey, B N ^a   Kendrick, H ^c   Yardley, V ^c   Caldera, A ^b   Lira, R ^b   Urbina, J A ^b   Moreno, S N J ^a   Docampo, R ^a   Croft, S L ^c   Oldfield, E ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; GERANYLTRANSFERASE; KETOCONAZOLE; NERIDRONIC ACID; OLPADRONIC ACID; PAMIDRONIC ACID; RISEDRONIC ACID;

ARTICLE; DRUG EFFECT; DRUG SCREENING; ENZYME INHIBITION; LEISHMANIA DONOVANI; NONHUMAN; PLASMODIUM FALCIPARUM; TOXOPLASMA GONDII; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

ANIMALS; ANTIPROTOZOAL AGENTS; CERCOPITHECUS AETHIOPS; DIPHOSPHONATES; LEISHMANIA DONOVANI; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP; TOXOPLASMA; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA CRUZI; VERO CELLS;

EID: 0035866666     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0002578     Document Type: Article

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