Comparative studies on the biochemical properties of the malic enzymes from Trypanosoma cruzi and Trypanosoma brucei

FEMS Microbiology Letters

Volumn 314, Issue 1, 2011, Pages 25-33

  Leroux, Alejandro E ^a   Maugeri, Dante A ^b   Opperdoes, Fred R ^c   Cazzulo, Juan J ^b   Nowicki, Cristina ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b INSTITUTO DE INVESTIGACIONES BIOTECNOLÓGICAS   (Argentina)

^c DE DUVE INSTITUTE   (Belgium)

Author keywords

Malic enzyme; Trypanosoma brucei; Trypanosoma cruzi

Indexed keywords

ASPARTIC ACID; GLUCOSE; MALATE DEHYDROGENASE (DECARBOXYLATING); NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PENTOSE PHOSPHATE; PROTOZOAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

AMASTIGOTE; BINDING AFFINITY; CATALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOSOL; ENZYME ANALYSIS; ENZYME KINETICS; LETTER; MITOCHONDRION; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

CYTOSOL; HUMANS; ISOENZYMES; KINETICS; MALATE DEHYDROGENASE; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; NADP; PROTEIN TRANSPORT; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA CRUZI; TRYPANOSOMIASIS;

HEXAPODA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

EID: 78650138914     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2010.02142.x     Document Type: Letter

References (30)

1. Aranda A, Maugeri D, Uttaro AD, Opperdoes F, Cazzulo JJ & Nowicki C (2006) The malate dehydrogenase isoforms from Trypanosoma brucei: subcellular localization and differential expression in bloodstream and procyclic forms. Int J Parasitol 36: 295-307.
2. Barrett MP, Burchmore RJ, Stich A, Lazzari JO, Frasch AC, Cazzulo JJ & Krishna S (2003) The trypanosomiases. Lancet 362: 1469-1480.
3. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
4. Brun R & Schonenberger (1979) Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Acta Trop 36: 289-292.
5. Cannata JJ, Frasch AC, Cataldi de Flombaum MA, Segura EL & Cazzulo JJ (1979) Two forms of 'malic' enzyme with different regulatory properties in Trypanosoma cruzi. Biochem J 184: 409-419.
6. Cazzulo Franke MC, Vernal J, Cazzulo JJ & Nowicki C (1999) The NAD-linked aromatic alpha-hydroxy acid dehydrogenase from Trypanosoma cruzi. A new member of the cytosolic malate dehydrogenases group without malate dehydrogenase activity. Eur J Biochem 266: 903-910.
7. Cazzulo JJ, Valle E, Docampo R & Cannata JJ (1980) Intracellular distribution of carbon dioxide-fixing enzymes in Trypanosoma cruzi and Crithidia fasciculata. J Gen Microbiol 117: 271-274.
8. Cazzulo JJ, Franke de Cazzulo BM, Engel JC & Cannata JJ (1985) End products and enzyme levels of aerobic glucose fermentation in trypanosomatids. Mol Biochem Parasit 16: 329-343.
9. Coustou V, Biran M, Breton M, Guegan F, Riviere L, Plazolles N, Nolan D, Barrett MP, Franconi JM & Bringaud F (2008) Glucose-induced remodeling of intermediary and energy metabolism in procyclic Trypanosoma brucei. J Biol Chem 283: 16342-16354.
10. Chang GG & Tong L (2003) Structure and function of malic enzymes, a new class of oxidative decarboxylases. Biochemistry 42: 12721-12733.
11. Donelson JE (2003) Antigenic variation and the African trypanosome genome. Acta Trop 85: 391-404.
12. Ferguson MA (1997) The surface glycoconjugates of trypanosomatid parasites. Philos T Roy Soc B 352: 1295-1302.
13. Franke de Cazzulo BM, Martinez J, North MJ, Coombs GH & Cazzulo JJ (1994) Effects of proteinase inhibitors on the growth and differentiation of Trypanosoma cruzi. FEMS Microbiol Lett 124: 81-6.
14. Fraser RDB & Suzuki E (1973) The use of least squares in the data analysis. Physical principles and techniques of protein chemistry (Leach S, ed.), pp. 301-355. Academic Press, New York.
15. Hanau S, Rinaldi E, Dallocchio F, Gilbert IH, Dardonville C, Adams MJ, Gover S & Barrett MP (2004) 6-Phosphogluconate dehydrogenase: a target for drugs in African trypanosomes. Curr Med Chem 11: 2639-2650.
16. Igoillo-Esteve M, Maugeri D, Stern AL, Beluardi P & Cazzulo JJ (2007) The pentose phosphate pathway in Trypanosoma cruzi: a potential target for the chemotherapy of chagas disease. An Acad Bras Cienc 79: 649-663.
17. Irigoin F, Cibils L, Comini MA, Wilkinson SR, Flohe L & Radi R (2008) Insights into the redox biology of Trypanosoma cruzi: trypanothione metabolism and oxidant detoxification. Free Radical Bio Med 45: 733-742.
18. Krauth-Siegel RL & Comini MA (2008) Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism. Biochim Biophys Acta 1780: 1236-1248.
19. Lanham SM & Godfrey DG (1970) Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose. Exp Parasitol 28: 521-534.
20. Lee SH, Stephens JL & Englund PT (2007) A fatty-acid synthesis mechanism specialized for parasitism. Nat Rev Microbiol 5: 287-297.
21. Marciano D, Llorente C, Maugeri DA, De La Fuente C, Opperdoes F, Cazzulo JJ & Nowicki C (2008) Biochemical characterization of stage-specific isoforms of aspartate aminotransferases from Trypanosoma cruzi and Trypanosoma brucei. Mol Biochem Parasit 161: 12-20.
22. Medina-Acosta E & Cross GA (1993) Rapid isolation of DNA from trypanosomatid protozoa using a simple 'mini-prep' procedure. Mol Biochem Parasit 59: 327-329.
23. Opperdoes FR & Cottem D (1982) Involvement of the glycosome of Trypanosoma brucei in carbon dioxide fixation. FEBS Lett 143: 49-51.
24. Schägger H & Von Jagow G (1987) Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 166: 368-379.
25. Silber AM, Tonelli RR, Lopes CG, Cunha-e-Silva N, Torrecilhas AC, Schumacher RI, Colli W & Alves MJ (2009) Glucose uptake in the mammalian stages of Trypanosoma cruzi. Mol Biochem Parasit 168: 102-108.
26. Tielens AG & Van Hellemond JJ (1998) Differences in energy metabolism between Trypanosomatidae. Parasitol Today 14: 265-272.
27. Tielens AG & Van Hellemond JJ (2009) Surprising variety in energy metabolism within Trypanosomatidae. Trends Parasitol 25: 482-490.
28. Urbina JA & Docampo R (2003) Specific chemotherapy of chagas disease: controversies and advances. Trends Parasitol 19: 495-501.
29. Vassella E, Straesser K & Boshart M (1997) A mitochondrion-specific dye for multicolour fluorescent imaging of Trypanosoma brucei. Mol Biochem Parasit 90: 381-385.
30. Wheeler MC, Arias CL, Tronconi MA, Maurino VG, Andreo CS & Drincovitch MF (2008) Arabidopsis thaliana NADP-malic enzyme isoforms: high degree of identity but clearly distinct properties. Plant Mol Biol 67: 231-242.