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Volumn 13, Issue 7, 2005, Pages 2637-2649

Design, synthesis and evaluation of 2,4-diaminoquinazolines as inhibitors of trypanosomal and leishmanial dihydrofolate reductase

(7) Khabnadideh, Soghra a,b Pez, Didier a Musso, Alexander c Brun, Reto d Ruiz Pérez, Luis M c González Pacanowska, Dolores c Gilbert, Ian H a

a CARDIFF UNIVERSITY (United Kingdom)

b SHIRAZ UNIVERSITY (Iran)

c INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA (Spain)

d SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINOQUINAZOLINE DERIVATIVE; 4 [2 (2,4 DIAMINO 6 QUINAZOLINYL)ETHYL]PHENOL; 6 [2 [4 (BENZYLOXY)PHENYL] 1 ETHENYL] 2,4 QUINAZOLINEDIAMINE; 6 [2 [4 (BENZYLOXY)PHENYL] 1 ETHYNYL] 2,4 QUINAZOLINEDIAMINE; 6 [4 (BENZYLOXY)PHENETHYL] 2,4 QUINAZOLINEDIAMINE; 6 [4 (BUTYLOXY)PHENETHYL] 2,4 QUINAZOLINEDIAMINE; 6 [4 (DECYLOXY)PHENETHYL] 2,4 QUINAZOLINEDIAMINE; 6 [4 (ETHOXY)PHENETHYL] 2,4 QUINAZOLINEDIAMINE; 6 [4 (HEXYLOXY)PHENETHYL] 2,4 QUINAZOLINEDIAMINE; 6 [4 (OCTYLOXY)PHENETHYL] 2,4 QUINAZOLINEDIAMINE; DIHYDROFOLATE REDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; LEISHMANIA DONOVANI; LEISHMANIASIS; NONHUMAN; TRYPANOSOMA CRUZI; TRYPANOSOMA RHODESIENSE; TRYPANOSOMIASIS;

EID: 14844291472 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2005.01.025 Document Type: Article

Times cited : (61)

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