The metabolism of proline, a stress substrate, modulates carcinogenic pathways

Amino Acids

Volumn 35, Issue 4, 2008, Pages 681-690

  Phang, James M ^a   Donald, Steven P ^a   Pandhare, Jui ^a   Liu, Yongmin ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

Apoptosis; Bioenergetics; mTOR; PPAR ; Proline dehydrogenase; Proline oxidase

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADENOSINE TRIPHOSPHATE; COLLAGEN; DEATH RECEPTOR; HYDROXYPROLINE; MAMMALIAN TARGET OF RAPAMYCIN; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; PROLINE; PROLINE DEHYDROGENASE; PROLINE DIPEPTIDASE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TROGLITAZONE;

AMINO ACID METABOLISM; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AUTOPHAGY; BIOENERGY; CARCINOGENESIS; CATALYSIS; COLLAGEN DEGRADATION; DRUG TARGETING; ENZYME SUBSTRATE; EXTRACELLULAR MATRIX; GENOTOXICITY; HUMAN; MICROENVIRONMENT; MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REVIEW;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; AUTOPHAGY; CATALYSIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIGANDS; MODELS, BIOLOGICAL; NEOPLASMS; PPAR DELTA; PROLINE; PROLINE OXIDASE; PROTEIN KINASES; THIAZOLIDINEDIONES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 53849096017     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-008-0063-4     Document Type: Review

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