Potent anti-Trypanosoma cruzi activities of oxidosqualene cyclase inhibitors

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 4, 2001, Pages 1210-1215

  Buckner, F S ^a   Griffin, J H ^a   Wilson, A J ^a   Van Voorhis, W C ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITRYPANOSOMAL AGENT; AROMATIC COMPOUND; BENZNIDAZOLE; LANOSTEROL; N 5,9,13 TRIMETHYL 4,8,12 TETRADECATRIEN 1 YLPYRIDINIUM; OXIDOSQUALENE CYCLASE INHIBITOR DERIVATIVE; SQUALENE DERIVATIVE; TERBINAFINE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG ACCUMULATION; ENZYME ACTIVITY; ENZYME INHIBITION; GROWTH INHIBITION; NONHUMAN; PRIORITY JOURNAL; SOUTH AND CENTRAL AMERICA; STEROL SYNTHESIS; TRYPANOSOMA CRUZI;

3T3 CELLS; ANIMALS; ANTIFUNGAL AGENTS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; INTRAMOLECULAR TRANSFERASES; KETOCONAZOLE; MICE; PARASITIC SENSITIVITY TESTS; SQUALENE; STEROLS; TRYPANOSOMA CRUZI;

EID: 0035076959     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.4.1210-1215.2001     Document Type: Article

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