메뉴 건너뛰기




Volumn 77, Issue 3, 1999, Pages 332-338

Chemotherapy of Chagas' disease: The how and the why

Author keywords

Chagas' disease; Chemotherapy; Nitrofurans; Nitroimidazoles autoimmunity; Sterol biosynthesis inhibitors; Trypanosoma cruzi

Indexed keywords

2 (2,4 DIFLUOROPHENYL) 1 [3 [2 [4 (2,2,3,3 TETRAFLUOROPROPOXY)PHENYL]VINYL] 1,2,4 TRIAZOL 1 YL] 3 (1,2,4 TRIAZOL 1 YL) 2 PROPANOL;

EID: 0033003357     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090050359     Document Type: Review
Times cited : (99)

References (63)
  • 2
    • 0030973773 scopus 로고    scopus 로고
    • Sterol biosynthesis inhibitors: Potential chemotherapeutics against Chagas disease
    • Docampo R, Schmuñis GA (1997) Sterol biosynthesis inhibitors: potential chemotherapeutics against Chagas disease. Parasitol Today 13:129-130
    • (1997) Parasitol Today , vol.13 , pp. 129-130
    • Docampo, R.1    Schmuñis, G.A.2
  • 4
    • 0027196445 scopus 로고
    • The challenge of Chagas disease chemotherapy: An update of drugs assayed against Trypansoma cruzi
    • de Castro Solange L (1993) The challenge of Chagas disease chemotherapy: an update of drugs assayed against Trypansoma cruzi. Acta Trop 53:83-98
    • (1993) Acta Trop , vol.53 , pp. 83-98
    • De Castro Solange, L.1
  • 6
    • 0002360092 scopus 로고    scopus 로고
    • Chemotherapy of human leishmaniasis and trypanosomiasis
    • Hide G, Mottram JC, Coombs GH, Holmes PH (eds) CAB International, London
    • Croft SL, Urbina JA, Brun R (1997) Chemotherapy of human leishmaniasis and trypanosomiasis. In: Hide G, Mottram JC, Coombs GH, Holmes PH (eds) Trypanomiasis and leishmaniasis. CAB International, London, pp 245-257
    • (1997) Trypanomiasis and Leishmaniasis , pp. 245-257
    • Croft, S.L.1    Urbina, J.A.2    Brun, R.3
  • 7
    • 0343467904 scopus 로고    scopus 로고
    • Inmunologia
    • Siqueira-Batista R, Corrêa AD, Huggins DW (eds) Cultura Medica, Rio de Janeiro
    • Quintas LEM, Siqueira-Batista R (1996) Inmunologia. In: Siqueira-Batista R, Corrêa AD, Huggins DW (eds) Molestia de Chagas. Cultura Medica, Rio de Janeiro, pp 53-74
    • (1996) Molestia de Chagas , pp. 53-74
    • Quintas, L.E.M.1    Siqueira-Batista, R.2
  • 8
    • 0030870893 scopus 로고    scopus 로고
    • Immunological control of Trypanosoma cruzi infection and pathogenesis of Chagas' disease
    • Brener Z, Gazzinelli RT (1997) Immunological control of Trypanosoma cruzi infection and pathogenesis of Chagas' disease. Int Arch Allergy Immunol 114:103-110
    • (1997) Int Arch Allergy Immunol , vol.114 , pp. 103-110
    • Brener, Z.1    Gazzinelli, R.T.2
  • 12
    • 0021150439 scopus 로고
    • Ketoconazole inhibition of intracellular multiplication of Trypanosoma cruzi and protection against a lethal infection with the organism
    • McCabe RE, Remington JS, Araujo FG (1984) Ketoconazole inhibition of intracellular multiplication of Trypanosoma cruzi and protection against a lethal infection with the organism. J Infect Dis 150:594-601
    • (1984) J Infect Dis , vol.150 , pp. 594-601
    • McCabe, R.E.1    Remington, J.S.2    Araujo, F.G.3
  • 13
    • 0022541328 scopus 로고
    • In vitro and in vivo effects of itraconazole against Trypanosoma cruzi
    • McCabe RE, Remington JS, Araujo FG (1986) In vitro and in vivo effects of itraconazole against Trypanosoma cruzi. Am J Trop Med Hyg 35:280-284
    • (1986) Am J Trop Med Hyg , vol.35 , pp. 280-284
    • McCabe, R.E.1    Remington, J.S.2    Araujo, F.G.3
  • 14
    • 0023177855 scopus 로고
    • Ketoconazole promotes parasitological cure of mice infected with Trypanosoma cruzi
    • McCabe RE, Remington JS, Araujo FJ (1987) Ketoconazole promotes parasitological cure of mice infected with Trypanosoma cruzi. Trans R Soc Trop Med Hyg 81:613-615
    • (1987) Trans R Soc Trop Med Hyg , vol.81 , pp. 613-615
    • McCabe, R.E.1    Remington, J.S.2    Araujo, F.J.3
  • 15
    • 0021299006 scopus 로고
    • Ketoconazole and other potent antimycotic azoles exhibit pronounced activity against Trypanosoma cruzi, Plasmodium berghei and Entamoeba histolytica in vivo
    • Raether W, Seidenath H (1984) Ketoconazole and other potent antimycotic azoles exhibit pronounced activity against Trypanosoma cruzi, Plasmodium berghei and Entamoeba histolytica in vivo. Z Parasitenkd 70:135-138
    • (1984) Z Parasitenkd , vol.70 , pp. 135-138
    • Raether, W.1    Seidenath, H.2
  • 16
    • 0022497077 scopus 로고
    • Effects of ketoconazole on sterol biosynthesis by Trypanosoma cruzi
    • Beach DH, Goad LJ, Holz GG Jr (1986) Effects of ketoconazole on sterol biosynthesis by Trypanosoma cruzi. Biochem Biophys Res Commun 135:851-856
    • (1986) Biochem Biophys Res Commun , vol.135 , pp. 851-856
    • Beach, D.H.1    Goad, L.J.2    Holz Jr., G.G.3
  • 17
    • 0024202590 scopus 로고
    • The activity of ketoconazole and other azoles against Trypanosoma cruzi: Biochemistry and chemotherapeutic action in vitro
    • Goad LJ, Berens RL, Marr JJ, Beach DH, Holz GG Jr (1989) The activity of ketoconazole and other azoles against Trypanosoma cruzi: biochemistry and chemotherapeutic action in vitro. Mol Biochem Parasitol 32:179-190
    • (1989) Mol Biochem Parasitol , vol.32 , pp. 179-190
    • Goad, L.J.1    Berens, R.L.2    Marr, J.J.3    Beach, D.H.4    Holz Jr., G.G.5
  • 18
    • 0024236768 scopus 로고
    • Concentration and time dependence of the effects of ketoconazole on growth and sterol biosynthesis in Trypanosoma (Schizotrypanum) cruzi epimastigotes
    • Larralde G, Vivas J, Urbina JA (1988) Concentration and time dependence of the effects of ketoconazole on growth and sterol biosynthesis in Trypanosoma (Schizotrypanum) cruzi epimastigotes. Acta Cient Venez 39:140-146
    • (1988) Acta Cient Venez , vol.39 , pp. 140-146
    • Larralde, G.1    Vivas, J.2    Urbina, J.A.3
  • 19
    • 0023681312 scopus 로고
    • Antiproliferative synergism of the allylamine SF-86327 and ketoconazole on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi
    • Urbina JA, Lazardi K, Aguirre T, Piras MM, Piras R (1988) Antiproliferative synergism of the allylamine SF-86327 and ketoconazole on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi. Antimicrob Agents Chemother 32:1237-1242
    • (1988) Antimicrob Agents Chemother , vol.32 , pp. 1237-1242
    • Urbina, J.A.1    Lazardi, K.2    Aguirre, T.3    Piras, M.M.4    Piras, R.5
  • 20
    • 0025726299 scopus 로고
    • Antiproliferative effects and mechanism of action of ICI 195,739, a novel bis-triazole derivative, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi
    • Urbina JA, Lazardi K, Aguirre T, Piras MM, Piras R (1991) Antiproliferative effects and mechanism of action of ICI 195,739, a novel bis-triazole derivative, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi. Antimicrob Agents Chemother 35:730-735
    • (1991) Antimicrob Agents Chemother , vol.35 , pp. 730-735
    • Urbina, J.A.1    Lazardi, K.2    Aguirre, T.3    Piras, M.M.4    Piras, R.5
  • 21
    • 0025872450 scopus 로고
    • Ultrastructural alterations induced by ICI 195,739, a bis triazole with strong antiproliferative action against Trypanosma (Schizotrypanum) cruzi
    • Lazardi K, Urbina JA, DeSouza W (1991) Ultrastructural alterations induced by ICI 195,739, a bis triazole with strong antiproliferative action against Trypanosma (Schizotrypanum) cruzi. Antimicrob Agents Chemother 35:736-740
    • (1991) Antimicrob Agents Chemother , vol.35 , pp. 736-740
    • Lazardi, K.1    Urbina, J.A.2    DeSouza, W.3
  • 25
    • 0024235435 scopus 로고
    • Failure of ketoconazole to cure chronic murine Chagas disease
    • McCabe RE (1988) Failure of ketoconazole to cure chronic murine Chagas disease. J Infect Dis 158:1408-1409
    • (1988) J Infect Dis , vol.158 , pp. 1408-1409
    • McCabe, R.E.1
  • 28
    • 0024157536 scopus 로고
    • Synthesis and structure-activity relationships of a novel antifungal agent ICI 195,739
    • St. Georgiev V (ed) Annals of the New York Academy of Sciences, New York
    • Boyle FT, Gilman DJ, Gravestock MB, Wardleworth JM (1988) Synthesis and structure-activity relationships of a novel antifungal agent ICI 195,739. In: St. Georgiev V (ed) Antifungal drugs. Annals of the New York Academy of Sciences, New York, Vol. 544 :86-100
    • (1988) Antifungal Drugs , vol.544 , pp. 86-100
    • Boyle, F.T.1    Gilman, D.J.2    Gravestock, M.B.3    Wardleworth, J.M.4
  • 29
    • 0024158269 scopus 로고
    • Activity of ICI 195,739 -a novel orally active bistriazole - In rodent models of fungal and protozoal infections
    • St. Georgiev V (ed) Annals of the New York Academy of Sciences, New York
    • Ryley JF, McGregor S, Wilson RG (1988) Activity of ICI 195,739 -a novel orally active bistriazole - in rodent models of fungal and protozoal infections. In: St. Georgiev V (ed) Antifungal drugs. Annals of the New York Academy of Sciences, New York, Vol. 544:310-328
    • (1988) Antifungal Drugs , vol.544 , pp. 310-328
    • Ryley, J.F.1    McGregor, S.2    Wilson, R.G.3
  • 30
    • 0027274006 scopus 로고
    • Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas disease
    • Maldonado RA, Molina J, Payares G, Urbina JA (1993) Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas disease. Antimicrob Agents Chemother 37:1353-1359
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 1353-1359
    • Maldonado, R.A.1    Molina, J.2    Payares, G.3    Urbina, J.A.4
  • 32
    • 0031941787 scopus 로고    scopus 로고
    • Antiproliferative effects of D0870 on Trypanosoma (Schizotrypanum) cruzi
    • Liendo A, Lazardi K, Urbina JA (1998) Antiproliferative effects of D0870 on Trypanosoma (Schizotrypanum) cruzi. J Antimicrob Chemother 41:197-205
    • (1998) J Antimicrob Chemother , vol.41 , pp. 197-205
    • Liendo, A.1    Lazardi, K.2    Urbina, J.A.3
  • 33
    • 0030921232 scopus 로고    scopus 로고
    • Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites
    • Urbina JA (1997) Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites. Parasitology 117:S91-S99
    • (1997) Parasitology , vol.117
    • Urbina, J.A.1
  • 34
    • 0028582022 scopus 로고
    • Use of a simplified polymerase chain reaction procedure to detect Trypanosoma cruzi in blood samples from chronic chagasic patients in a rural endemic area
    • Wincker P, Britto C, Borges-Pereira J, Cardoso MA, Oelemann W, Morel CM (1994) Use of a simplified polymerase chain reaction procedure to detect Trypanosoma cruzi in blood samples from chronic chagasic patients in a rural endemic area. Am J Trop Med Hyg 51:771-777
    • (1994) Am J Trop Med Hyg , vol.51 , pp. 771-777
    • Wincker, P.1    Britto, C.2    Borges-Pereira, J.3    Cardoso, M.A.4    Oelemann, W.5    Morel, C.M.6
  • 35
    • 0027428255 scopus 로고
    • A simple protocol for the physical cleavage of Trypanosoma cruzi kinetoplast DNA present in blood samples and its use in polymerase chain reaction (PCR)-based diagnosis of chronic Chagas disease
    • Britto C, Cardoso MA, Wincker P, Morel CM (1993) A simple protocol for the physical cleavage of Trypanosoma cruzi kinetoplast DNA present in blood samples and its use in polymerase chain reaction (PCR)-based diagnosis of chronic Chagas disease. Mem Inst Oswaldo Cruz 88:171-172
    • (1993) Mem Inst Oswaldo Cruz , vol.88 , pp. 171-172
    • Britto, C.1    Cardoso, M.A.2    Wincker, P.3    Morel, C.M.4
  • 37
    • 26444601421 scopus 로고    scopus 로고
    • Therapeutic effects of the triazole D0870 inhibitor of sterol biosynthesis on different Trypanosoma cruzi strains
    • Molina J, Araújo MSS, Pereira MES, Urbina JA, Brener Z (1996) Therapeutic effects of the triazole D0870 inhibitor of sterol biosynthesis on different Trypanosoma cruzi strains. Mem Inst Oswaldo Cruz 91 [Suppl] 1:515
    • (1996) Mem Inst Oswaldo Cruz , vol.91 , Issue.1 SUPPL. , pp. 515
    • Molina, J.1    Araújo, M.S.S.2    Pereira, M.E.S.3    Urbina, J.A.4    Brener, Z.5
  • 38
    • 0027281091 scopus 로고
    • Activities of the triazole D0870 in vitro and against murine blastomycosis
    • Clemons KV, Hanson LH, Stevens DA (1993) Activities of the triazole D0870 in vitro and against murine blastomycosis. Antimicrob Agents Chemother 37:1177-1179
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 1177-1179
    • Clemons, K.V.1    Hanson, L.H.2    Stevens, D.A.3
  • 39
    • 0008894125 scopus 로고
    • Pharmacokinetics of two multiple dosing regimens of D0870 in HIV positive patients: A phase I study
    • De Wit S, O'Doherty E, Smith RP, Yates R, Clumeck N (1995) Pharmacokinetics of two multiple dosing regimens of D0870 in HIV positive patients: a phase I study. ICAAC Abstr 35:F97
    • (1995) ICAAC Abstr , vol.35
    • De Wit, S.1    O'Doherty, E.2    Smith, R.P.3    Yates, R.4    Clumeck, N.5
  • 40
    • 0030001767 scopus 로고    scopus 로고
    • In vitro and in vivo activities of SCH 56592 against Blastomyces dermatitidis
    • Sugar AM, Liu X-P (1996) In vitro and in vivo activities of SCH 56592 against Blastomyces dermatitidis. Antimicrob Agents Chemother 40:1314-1316
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1314-1316
    • Sugar, A.M.1    Liu, X.-P.2
  • 41
    • 0029817614 scopus 로고    scopus 로고
    • In vitro and in vivo efficacies of the azole SCH56592 against Cryptococcus neoformans
    • Perfect JR, Cox GM, Dodge RK, Schell WA (1996) In vitro and in vivo efficacies of the azole SCH56592 against Cryptococcus neoformans. Antimicrob Agents Chemother 40:1910-1913
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1910-1913
    • Perfect, J.R.1    Cox, G.M.2    Dodge, R.K.3    Schell, W.A.4
  • 42
    • 0031054149 scopus 로고    scopus 로고
    • Activity of a new triazole, SCH 56592, compared with those of four other antifungal agets tested against clinical isolates of Candida spp and Saccharomyces cerevisiae
    • Pfaller MA, Messer S, Jones RN (1997) Activity of a new triazole, SCH 56592, compared with those of four other antifungal agets tested against clinical isolates of Candida spp and Saccharomyces cerevisiae. Antimicrob Agents Chemother 41:233-235
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 233-235
    • Pfaller, M.A.1    Messer, S.2    Jones, R.N.3
  • 43
    • 3042558445 scopus 로고    scopus 로고
    • In vitro and in vivo antiproliferative effects of SCH 56592 against Trypanosoma cruzi, the causative agent of Chagas disease
    • Urbina JA, Payares G, Sanoja C, Contreras LM, Liendo A, Piras MM, Piras R (1996) In vitro and in vivo antiproliferative effects of SCH 56592 against Trypanosoma cruzi, the causative agent of Chagas disease. ICAAC Abstr 36:F102
    • (1996) ICAAC Abstr , vol.36
    • Urbina, J.A.1    Payares, G.2    Sanoja, C.3    Contreras, L.M.4    Liendo, A.5    Piras, M.M.6    Piras, R.7
  • 47
    • 0008940515 scopus 로고    scopus 로고
    • SCH 56592: Rising multiple-dose safety, tolerance, and pharmacokinetic evaluation in healthy volunteers
    • Laughlin M, Pai S, Menon S, Nomeir A, Colucci R, Affrime M, Kosoglou T (1997) SCH 56592: rising multiple-dose safety, tolerance, and pharmacokinetic evaluation in healthy volunteers. ICAAC Abstr 37:A87
    • (1997) ICAAC Abstr , vol.37
    • Laughlin, M.1    Pai, S.2    Menon, S.3    Nomeir, A.4    Colucci, R.5    Affrime, M.6    Kosoglou, T.7
  • 48
    • 0028939403 scopus 로고
    • Autoinmunity in Chagas disease cardiopathy: Biological relevance of a cardiac myosin-specific epitope crossreactive to an inmunodominant Trypanosoma cruzi antigen
    • Cunha-Neto E, Duranti M, Gruber A, Zingales B, De Messias I, Stolf N, Bellotti G, Patarroyo ME, Kalil J (1995) Autoinmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an inmunodominant Trypanosoma cruzi antigen. Proc Natl Acad Sci USA 92:3541-3545
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3541-3545
    • Cunha-Neto, E.1    Duranti, M.2    Gruber, A.3    Zingales, B.4    De Messias, I.5    Stolf, N.6    Bellotti, G.7    Patarroyo, M.E.8    Kalil, J.9
  • 49
    • 0030271981 scopus 로고    scopus 로고
    • Autoimmunity in Chagas disease cardiomyopathy: Fulfilling the criteria at last?
    • Kalil J, Cunha-Neto E (1996) Autoimmunity in Chagas disease cardiomyopathy: fulfilling the criteria at last? Parasitol Today 12:396-399
    • (1996) Parasitol Today , vol.12 , pp. 396-399
    • Kalil, J.1    Cunha-Neto, E.2
  • 50
    • 0029924487 scopus 로고    scopus 로고
    • Role of parasites in the pathogenesis of Chagas' cardiomyopathy
    • Bestetti RB (1996) Role of parasites in the pathogenesis of Chagas' cardiomyopathy. Lancet 347:913-914
    • (1996) Lancet , vol.347 , pp. 913-914
    • Bestetti, R.B.1
  • 51
    • 0041340096 scopus 로고    scopus 로고
    • Should benznidazole be used in chronic Chagas' disease?
    • Bestetti RB (1997) Should benznidazole be used in chronic Chagas' disease? Lancet 349:653
    • (1997) Lancet , vol.349 , pp. 653
    • Bestetti, R.B.1
  • 55
    • 0001697870 scopus 로고    scopus 로고
    • In chronic Chagas heart disease, don't forget the parasite
    • Levin MJ (1996) In chronic Chagas heart disease, don't forget the parasite. Parasitol Today 12:415-416
    • (1996) Parasitol Today , vol.12 , pp. 415-416
    • Levin, M.J.1
  • 56
    • 0030933295 scopus 로고    scopus 로고
    • "Autoinmune rejection" of neonatal heart transplants in experimental Chagas disease is a parasite-specific response to infected host tissue
    • Tarleton RL, Zhang L, Downs MO (1997) "Autoinmune rejection" of neonatal heart transplants in experimental Chagas disease is a parasite-specific response to infected host tissue. Proc Natl Acad Sci USA 94:3932-3937
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3932-3937
    • Tarleton, R.L.1    Zhang, L.2    Downs, M.O.3
  • 57
    • 0028281133 scopus 로고
    • Antibodies to beta-adrenergic receptors disclosing agonist-like properties in idiopathic dilated cardiomyopathy and Chagas' heart disease
    • Rosenbaum MB, Chiale PA, Schejtman D, Levin MJ, Elizari MV (1994) Antibodies to beta-adrenergic receptors disclosing agonist-like properties in idiopathic dilated cardiomyopathy and Chagas' heart disease. J Cardiovasc Electrophysiol 5:367-375
    • (1994) J Cardiovasc Electrophysiol , vol.5 , pp. 367-375
    • Rosenbaum, M.B.1    Chiale, P.A.2    Schejtman, D.3    Levin, M.J.4    Elizari, M.V.5
  • 58
    • 0030885253 scopus 로고    scopus 로고
    • Antibodies to ribosomal P proteins of Trypanosoma cruzi in Chagas disease possess functional autoreactivity with heart tissue and differ from anti-P autoantibodies in lupus
    • Kaplan D, Ferrari I, Lopez-Bergami P, Mahler E, Levitus G, Chiale P, Hoebeke J, Van Regenmortel MHV, Levin MJ (1997) Antibodies to ribosomal P proteins of Trypanosoma cruzi in Chagas disease possess functional autoreactivity with heart tissue and differ from anti-P autoantibodies in lupus. Proc Natl Acad Sci USA 94:10301-10306
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10301-10306
    • Kaplan, D.1    Ferrari, I.2    Lopez-Bergami, P.3    Mahler, E.4    Levitus, G.5    Chiale, P.6    Hoebeke, J.7    Van Regenmortel, M.H.V.8    Levin, M.J.9
  • 59
    • 0026143353 scopus 로고
    • Reversibility of cardiac fibrosis in mice chronically infected with Trypanosoma cruzi, under specific chemotherapy
    • Andrade SG, Stocker-Guerret S, Pimentel AS, Grimaud JA (1991) Reversibility of cardiac fibrosis in mice chronically infected with Trypanosoma cruzi, under specific chemotherapy. Mem Inst Oswaldo Cruz 86:187-200
    • (1991) Mem Inst Oswaldo Cruz , vol.86 , pp. 187-200
    • Andrade, S.G.1    Stocker-Guerret, S.2    Pimentel, A.S.3    Grimaud, J.A.4
  • 60
    • 0027955005 scopus 로고
    • Treatment of chronic Chagas' disease with benznidazole: Clinical and serologic evolution of patients with long-term follow-up
    • Viotti R, Vigliano C, Armenti H, Segura E (1994) Treatment of chronic Chagas' disease with benznidazole: clinical and serologic evolution of patients with long-term follow-up. Am Heart J 127:151-162
    • (1994) Am Heart J , vol.127 , pp. 151-162
    • Viotti, R.1    Vigliano, C.2    Armenti, H.3    Segura, E.4
  • 62
    • 0041340096 scopus 로고    scopus 로고
    • Should benznidazole be used in chronic Chagas' disease?
    • Andrade ALS, Zicker F (1997) Should benznidazole be used in chronic Chagas' disease? Lancet 349:653
    • (1997) Lancet , vol.349 , pp. 653
    • Andrade, A.L.S.1    Zicker, F.2
  • 63
    • 0028866134 scopus 로고
    • The mechanism of Trypanosoma cruzi invasion of mammalian cells
    • Burleigh BA, Andrews NW (1995) The mechanism of Trypanosoma cruzi invasion of mammalian cells. Annu Rev Microbiol 49:175-200
    • (1995) Annu Rev Microbiol , vol.49 , pp. 175-200
    • Burleigh, B.A.1    Andrews, N.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.