Microbiology: The Trypanosoma cruzi proteome

Science

Volumn 309, Issue 5733, 2005, Pages 473-476

  Atwood III, J A ^a   Weatherly, D B ^a   Minning, T A ^a   Bundy, B ^a   Cavola, C ^a   Opperdoes, F R ^b   Orlando, R ^a   Tarleton, R L ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b DE DUVE INSTITUTE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACIDS; GENES; MICROBIOLOGY;

HISTIDINE; KINETOPLASTID GENOMES; SURFACE PROTEINS;

PROTEINS;

PROTEOME; ENZYME; GLYCOPROTEIN; HISTIDINE; MEMBRANE PROTEIN; MUCIN; PARASITE ANTIGEN; PEPTIDE; PROTOZOAL PROTEIN; SIALIDASE; TRANS SIALIDASE; TRANS-SIALIDASE;

GENOME;

AMASTIGOTE; ARTICLE; EPIMASTIGOTE; FLAGELLATE; GENE SEQUENCE; GENOME ANALYSIS; LIFE CYCLE; MULTIGENE FAMILY; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEOMICS; TRYPANOSOMA CRUZI; ADAPTATION; ANIMAL; BIOLOGY; CHEMISTRY; ENERGY METABOLISM; GENE; GENETIC DATABASE; GENETICS; GENOME; GROWTH, DEVELOPMENT AND AGING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; PROTEIN TRANSPORT;

INSECTA; KINETOPLASTIDA; TRYPANOSOMA CRUZI;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANTIGENS, PROTOZOAN; CHROMATOGRAPHY, LIQUID; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; ENERGY METABOLISM; ENZYMES; GENES, PROTOZOAN; GENOME, PROTOZOAN; GLYCOPROTEINS; HISTIDINE; LIFE CYCLE STAGES; MASS SPECTROMETRY; MEMBRANE PROTEINS; MUCINS; MULTIGENE FAMILY; NEURAMINIDASE; PEPTIDES; PROTEIN TRANSPORT; PROTEOME; PROTOZOAN PROTEINS; TRYPANOSOMA CRUZI;

EID: 22244440786     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1110289     Document Type: Article

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26. The authors thank the TSK-TSC for providing access to genome sequence data before and after assembly and public release of an annotated genome, K. Tyler and D. Hoft for assistance in the production of metacyclic stages, L. Cheng for technical assistance, C. Reese for artwork, B. Striepen for comments on the manuscript, and S. Kring Sullivan for early work on mass spectrometric analysis of T, cruzi. This work is supported by NIH grant POI AI044979 to R.L.T. Data on all peptides mapping to annotated genes is available on TcruziDB (http://tcruzidb.org). Raw data in either the original peak-list (.PKL) format or in mzData XML format (Minimum Information About a Proteomics Experiment standard) can be downloaded from http://kiwi.rcr.uga.edu/tcprot/downloads.html Complete lists of all peptides identified, prerun queries identifying proteins expressed in specific life-cycle stages, and tools to query and view these data are also available on http://tcruzidb.org and/or http://kiwi.rcr.uga.edu/ tcprot.