-
1
-
-
56249134213
-
Discovery of drug-like inhibitors of an essential RNA-editing ligase in Trypanosoma brucei
-
Amaro RE, Schnaufer A, Interthal H, Hol W, Stuart KD, McCammon JA. 2008. Discovery of drug-like inhibitors of an essential RNA-editing ligase in Trypanosoma brucei. Proc Natl Acad Sci 105: 17278-17283.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 17278-17283
-
-
Amaro, R.E.1
Schnaufer, A.2
Interthal, H.3
Hol, W.4
Stuart, K.D.5
McCammon, J.A.6
-
2
-
-
0037450771
-
Isolation of a U-insertion/deletion editing complex from Leishmania tarentolae mitochondria
-
Aphasizhev R, Aphasizheva I, Nelson RE, Gao G, Simpson AM, Kang X, Falick AM, Sbicego S, Simpson L. 2003. Isolation of a U-insertion/deletion editing complex from Leishmania tarentolae mitochondria. EMBO J 22: 913-924.
-
(2003)
EMBO J
, vol.22
, pp. 913-924
-
-
Aphasizhev, R.1
Aphasizheva, I.2
Nelson, R.E.3
Gao, G.4
Simpson, A.M.5
Kang, X.6
Falick, A.M.7
Sbicego, S.8
Simpson, L.9
-
3
-
-
0025189769
-
A model for RNA editing in kinetoplastid mitochondria: "Guide" RNA molecules transcribed from maxicircle DNA provide the edited information
-
Blum B, Bakalara N, Simpson L. 1990. A model for RNA editing in kinetoplastid mitochondria: "Guide" RNA molecules transcribed from maxicircle DNA provide the edited information. Cell 60: 189-198.
-
(1990)
Cell
, vol.60
, pp. 189-198
-
-
Blum, B.1
Bakalara, N.2
Simpson, L.3
-
4
-
-
0033525864
-
A cis-acting A-U sequence element induces kinetoplastid U-insertions
-
Brown LM, Burbach BJ, McKenzie BA, Connell GJ. 1999. A cis-acting A-U sequence element induces kinetoplastid U-insertions. J Biol Chem 274: 6295-6304.
-
(1999)
J Biol Chem
, vol.274
, pp. 6295-6304
-
-
Brown, L.M.1
Burbach, B.J.2
McKenzie, B.A.3
Connell, G.J.4
-
5
-
-
0036173906
-
RNA sequence and base pairing effects on insertion editing in Trypanosoma brucei
-
Igo RP Jr, Lawson SD, Stuart K. 2002. RNA sequence and base pairing effects on insertion editing in Trypanosoma brucei. Mol Cell Biol 22: 1567-1576.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1567-1576
-
-
Igo Jr., R.P.1
Lawson, S.D.2
Stuart, K.3
-
6
-
-
0029788229
-
RNA editing: A mechanism for gRNA-specified uridylate insertion into precursor mRNA
-
Kable ML, Seiwert SD, Heidmann S, Stuart K. 1996. RNA editing: A mechanism for gRNA-specified uridylate insertion into precursor mRNA. Science 273: 1189-1195. (Pubitemid 26293201)
-
(1996)
Science
, vol.273
, Issue.5279
, pp. 1189-1195
-
-
Kable, M.L.1
Seiwert, S.D.2
Heidmann, S.3
Stuart, K.4
-
7
-
-
0032827799
-
A simple and efficient method to reduce nontemplated nucleotide addition at the 3' terminus of RNAs transcribed by T7 RNA polymerase
-
DOI 10.1017/S1355838299991033
-
Kao C, Zheng M, Rudisser S. 1999. A simple and efficient method to reduce nontemplated nucleotide addition at the 3 terminus of RNAs transcribed by T7 RNA polymerase. RNA 5: 1268-1272. (Pubitemid 29422768)
-
(1999)
RNA
, vol.5
, Issue.9
, pp. 1268-1272
-
-
Kao, C.1
Zheng, M.2
Rudisser, S.3
-
8
-
-
17144460676
-
The discovery of potent cRaf1 kinase inhibitors
-
Lackey K, Cory M, Davis R, Frye SV, Harris PA, Hunter RN, Jung DK, McDonald OB, McNutt RW, Peel MR, et al. 2000. The discovery of potent cRaf1 kinase inhibitors. Bioorg Med Chem Lett 10: 223-226.
-
(2000)
Bioorg Med Chem Lett
, vol.10
, pp. 223-226
-
-
Lackey, K.1
Cory, M.2
Davis, R.3
Frye, S.V.4
Harris, P.A.5
Hunter, R.N.6
Jung, D.K.7
McDonald, O.B.8
McNutt, R.W.9
Peel, M.R.10
-
9
-
-
70349102542
-
An electrochemiluminescent aptamer switch for a high-throughput assay of an RNA editing reaction
-
Liang S, Connell GJ. 2009. An electrochemiluminescent aptamer switch for a high-throughput assay of an RNA editing reaction. RNA 15: 1929-1938.
-
(2009)
RNA
, vol.15
, pp. 1929-1938
-
-
Liang, S.1
Connell, G.J.2
-
10
-
-
0037061628
-
A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening
-
McGovern SL, Caselli E, Grigorieff N, Shoichet BK. 2002. A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening. J Med Chem 45: 1712-1722.
-
(2002)
J Med Chem
, vol.45
, pp. 1712-1722
-
-
McGovern, S.L.1
Caselli, E.2
Grigorieff, N.3
Shoichet, B.K.4
-
11
-
-
0024819449
-
Synthesis of small RNAs using T7 RNA polymerase
-
Milligan JF, Uhlenbeck OC. 1989. Synthesis of small RNAs using T7 RNA polymerase. Methods Enzymol 180: 51-62.
-
(1989)
Methods Enzymol
, vol.180
, pp. 51-62
-
-
Milligan, J.F.1
Uhlenbeck, O.C.2
-
12
-
-
0036275535
-
Direct visualization of RNA editing within a Leishmania mitochondrial extract
-
Oppegard LM, Connell GJ. 2002. Direct visualization of RNA editing within a Leishmania mitochondrial extract. Int J Parasitol 32: 859-866.
-
(2002)
Int J Parasitol
, vol.32
, pp. 859-866
-
-
Oppegard, L.M.1
Connell, G.J.2
-
13
-
-
0034721817
-
Activation of guide RNA-directed editing of a cytochrome b mRNA
-
Oppegard LM, Kabb AL, Connell GJ. 2000. Activation of guide RNA-directed editing of a cytochrome b mRNA. J Biol Chem 275: 33911-33919.
-
(2000)
J Biol Chem
, vol.275
, pp. 33911-33919
-
-
Oppegard, L.M.1
Kabb, A.L.2
Connell, G.J.3
-
14
-
-
0346435100
-
Cis-acting elements stimulating kinetoplastid guide RNA-directed editing
-
Oppegard LM, Hillestad M, McCarthy RT, Pai RD, Connell GJ. 2003. Cis-acting elements stimulating kinetoplastid guide RNA-directed editing. J Biol Chem 278: 51167-51175.
-
(2003)
J Biol Chem
, vol.278
, pp. 51167-51175
-
-
Oppegard, L.M.1
Hillestad, M.2
McCarthy, R.T.3
Pai, R.D.4
Connell, G.J.5
-
15
-
-
0037377351
-
Sequence and structural requirements for optimal guide RNA-directed insertional editing within Leishmania tarentolae
-
Pai RD, Oppegard LM, Connell GJ. 2003. Sequence and structural requirements for optimal guide RNA-directed insertional editing within Leishmania tarentolae. RNA 9: 469-483.
-
(2003)
RNA
, vol.9
, pp. 469-483
-
-
Pai, R.D.1
Oppegard, L.M.2
Connell, G.J.3
-
16
-
-
0035164020
-
Association of two novel proteins, TbMP52 and TbMP48, with the Trypanosoma brucei RNA editing complex
-
DOI 10.1128/MCB.21.2.380-389.2001
-
Panigrahi AK, Gygi SP, Ernst NL, Igo RP, Palazzo SS, Schnaufer A, Weston DS, Carmean N, Salavati R, Aebersold R, et al. 2001. Association of two novel proteins, TbMP52 and TbMP48, with the Trypanosoma brucei RNA editing complex. Mol Cell Biol 21: 380-389. (Pubitemid 32037359)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.2
, pp. 380-389
-
-
Panigrahi, A.K.1
Gygi, S.P.2
Ernst, N.L.3
Igo Jr., R.P.4
Palazzo, S.S.5
Schnaufer, A.6
Weston, D.S.7
Carmean, N.8
Salavati, R.9
Aebersold, R.10
Stuart, K.D.11
-
17
-
-
0037379043
-
Identification of novel components of Trypanosoma brucei editosomes
-
DOI 10.1261/rna.2194603
-
Panigrahi AK, Schnaufer A, Ernst NL, Wang B, Carmean N, Salavati R, Stuart K. 2003. Identification of novel components of Trypanosoma brucei editosomes. RNA 9: 484-492. (Pubitemid 36356734)
-
(2003)
RNA
, vol.9
, Issue.4
, pp. 484-492
-
-
Panigrahi, A.K.1
Schnaufer, A.2
Ernst, N.L.3
Wang, B.4
Carmean, N.5
Salavati, R.6
Stuart, K.7
-
18
-
-
0030928201
-
Purification of a functional enzymatic editing complex from Trypanosoma brucei mitochondria
-
Rusche LN, Cruzreyes J, Piller KJ, Sollnerwebb B. 1997. Purification of a functional enzymatic editing complex from Trypanosoma brucei mitochondria. EMBO J 16: 4069-4081.
-
(1997)
EMBO J
, vol.16
, pp. 4069-4081
-
-
Rusche, L.N.1
Cruzreyes, J.2
Piller, K.J.3
Sollnerwebb, B.4
-
19
-
-
0037177902
-
Genetic rescue of Leishmania deficiency in porphyrin biosynthesis creates mutants suitable for analysis of cellular events in uroporphyria and for photodynamic therapy
-
Sah JF, Ito H, Kolli BK, Peterson DA, Sassa S, Chang K. 2002. Genetic rescue of Leishmania deficiency in porphyrin biosynthesis creates mutants suitable for analysis of cellular events in uroporphyria and for photodynamic therapy. J Biol Chem 277: 14902-14909.
-
(2002)
J Biol Chem
, vol.277
, pp. 14902-14909
-
-
Sah, J.F.1
Ito, H.2
Kolli, B.K.3
Peterson, D.A.4
Sassa, S.5
Chang, K.6
-
20
-
-
0035896357
-
An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei
-
Schnaufer A, Panigrahi AK, Panicucci B, Igo RP Jr, Wirtz E, Salavati R, Stuart K. 2001. An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei. Science 291: 2159-2162.
-
(2001)
Science
, vol.291
, pp. 2159-2162
-
-
Schnaufer, A.1
Panigrahi, A.K.2
Panicucci, B.3
Igo Jr., R.P.4
Wirtz, E.5
Salavati, R.6
Stuart, K.7
-
21
-
-
0029942430
-
Direct visualization of uridylate deletion in vitro suggests a mechanism for kinetoplastid RNA editing
-
Seiwert SD, Heidmann S, Stuart K. 1996. Direct visualization of uridylate deletion in vitro suggests a mechanism for kinetoplastid RNA editing. Cell 84: 831-841.
-
(1996)
Cell
, vol.84
, pp. 831-841
-
-
Seiwert, S.D.1
Heidmann, S.2
Stuart, K.3
-
22
-
-
41849094126
-
Kinetoplastids: Related protozoan pathogens, different diseases
-
Stuart K, Brun R, Croft S, Fairlamb A, Gurtler RE, McKerrow J, Reed S, Tarleton R. 2008. Kinetoplastids: Related protozoan pathogens, different diseases. J Clin Invest 118: 1301-1310.
-
(2008)
J Clin Invest
, vol.118
, pp. 1301-1310
-
-
Stuart, K.1
Brun, R.2
Croft, S.3
Fairlamb, A.4
Gurtler, R.E.5
McKerrow, J.6
Reed, S.7
Tarleton, R.8
-
24
-
-
0033003760
-
A simple statistical parameter for use in evaluation and validation of high throughput screening assays
-
Zhang JH, Chung TD, Oldenburg K. 1999. A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 4: 67-73.
-
(1999)
J Biomol Screen
, vol.4
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.3
-
25
-
-
33847209549
-
Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania
-
DOI 10.1038/sj.emboj.7601565, PII 7601565
-
Zhang K, Pompey JM, Hsu F, Key P, Padmavathi B, Saba JD, Turk J, Beverley SM. 2007. Redirection of sphingolipid metabolism toward de nova synthesis of ethanolamine in Leishmania. EMBO J 26: 1094-1104. (Pubitemid 46303588)
-
(2007)
EMBO Journal
, vol.26
, Issue.4
, pp. 1094-1104
-
-
Zhang, K.1
Pompey, J.M.2
Hsu, F.-F.3
Key, P.4
Bandhuvula, P.5
Saba, J.D.6
Turk, J.7
Beverley, S.M.8
-
26
-
-
65749105061
-
Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone)
-
Zheng S, Chen Y, Donahue CP, Wolfe MS, Varani G. 2009. Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone). Chem Biol 16: 557-566.
-
(2009)
Chem Biol
, vol.16
, pp. 557-566
-
-
Zheng, S.1
Chen, Y.2
Donahue, C.P.3
Wolfe, M.S.4
Varani, G.5
|