Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite

Biochemical Journal

Volumn 410, Issue 2, 2008, Pages 359-368

  Piacenza, Lucía ^a   Peluffo, Gonzalo ^a   Alvarez, María Noel ^a   Kelly, John M ^b   Wilkinson, Shane R ^b   Radi, Rafael ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Cytosolic peroxiredoxin; Macrophages; Mitochondrial peroxiredoxin; Peroxynitrite; Trypanosoma cruzi; Virulence

Indexed keywords

AMINO ACIDS; MACROPHAGES; NITROGEN; OXYGEN; REDOX REACTIONS;

PEROXIREDOXINS; TRYPAREDOXIN PEROXIDASE;

ENZYME ACTIVITY;

3 NITROTYROSINE; 5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; ASCORBIC ACID; HYDROGEN PEROXIDE; MITOCHONDRIAL ENZYME; NITRITE; NITROGEN; PEROXIDASE; PEROXIREDOXIN; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CYTOTOXICITY; DECOMPOSITION; DETOXIFICATION; FLUORESCENCE; GENE OVEREXPRESSION; IN VITRO STUDY; INTRACELLULAR SPACE; MACROPHAGE ACTIVATION; MOLECULAR PROBE; MOUSE; NONHUMAN; PARASITE VIRULENCE; PRIORITY JOURNAL; PROTEIN ISOLATION; REDUCTION KINETICS; TRYPANOSOMA CRUZI;

ANIMALS; CHAGAS DISEASE; HUMANS; KINETICS; LATIN AMERICA; MACROPHAGES; MICE; MUTAGENESIS, SITE-DIRECTED; PEROXIREDOXINS; PEROXYNITROUS ACID; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI; VIRULENCE;

TRYPANOSOMA CRUZI;

EID: 40449096623     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20071138     Document Type: Article

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