Mechanism of action of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the causative agent of Chagas' disease

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 6, 2003, Pages 2047-2050

  Urbina, Julio A ^a   Concepcion, Juan Luis ^b   Montalvetti, Andrea ^c   Rodriguez, Juan B ^d   Docampo, Roberto ^c  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^b UNIVERSIDAD DE LOS ANDES   (Venezuela)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

4 PHENOXYPHENOXYETHYL THIOCYANATE; ANTIPROTOZOAL AGENT; SQUALENE SYNTHASE; STEROL; UNCLASSIFIED DRUG; WC 9;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; EPIMASTIGOTE; GROWTH INHIBITION; NONHUMAN; PRIORITY JOURNAL; STEROL SYNTHESIS; TRYPANOSOMA CRUZI;

ALKYL AND ARYL TRANSFERASES; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERGOSTEROL; FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE; GERANYLTRANSTRANSFERASE; HUMANS; MICROBIAL SENSITIVITY TESTS; PHENYL ETHERS; THIOCYANATES; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 0038778632     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.6.2047-2050.2003     Document Type: Article

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