Interleukin-targeted therapy for metabolic syndrome and type 2 diabetes

Handbook of Experimental Pharmacology

Volumn 203, Issue , 2011, Pages 257-278

  Maedler, Kathrin ^a   Dharmadhikari, Gitanjali ^a   Schumann, Desiree M ^b   Størling, Joachim ^c  

^a UNIVERSITY OF BREMEN   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c HAGEDORN RESEARCH INSTITUTE   (Denmark)

Author keywords

Diabetes; IL 1 ; Inflammation; Interleukin 1 receptor antagonist; Obesity; Cell

Indexed keywords

GEVOKIZUMAB; INSULIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA ANTIBODY; PLACEBO; INTERLEUKIN DERIVATIVE;

ADIPOCYTE; BRAIN; CELLULAR DISTRIBUTION; CYTOKINE RELEASE; DISEASE COURSE; DISEASE MODEL; DRUG MECHANISM; DRUG TARGETING; HORMONE ACTION; HUMAN; IN VITRO STUDY; INFLAMMATION; INSULIN RELEASE; INSULIN RESISTANCE; LIVER; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; ANIMAL; DRUG ANTAGONISM; METABOLISM; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADIPOCYTES; ANIMALS; BRAIN; DIABETES MELLITUS, TYPE 2; HUMANS; INSULIN-SECRETING CELLS; INTERLEUKIN-1BETA; INTERLEUKINS; LIVER; METABOLIC SYNDROME X; MICE; OBESITY; SIGNAL TRANSDUCTION;

EID: 79955615961     PISSN: 01712004     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-17214-4_11     Document Type: Review

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