Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?

Diabetes

Volumn 54, Issue 11, 2005, Pages 3238-3244

  Welsh, Nils ^a   Cnop, Miriam ^b,c   Kharroubi, Ilham ^b   Bugliani, Marco ^d   Lupi, Roberto ^d   Marchetti, Piero ^d   Eizirik, Décio L ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c ERASME HOSPITAL   (Belgium)

^d UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; GLUCOSE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN;

ADULT; AGED; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL DEATH; CELL ISOLATION; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; FEMALE; GENE ACTIVATION; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MONOCYTE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

AGED; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUCOSE; HUMANS; INTERLEUKIN-1; ISLETS OF LANGERHANS; MALE; MIDDLE AGED; TIME FACTORS;

EID: 33644669584     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/diabetes.54.11.3238     Document Type: Article

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