메뉴 건너뛰기




Volumn 61, Issue 12, 2001, Pages 1561-1569

Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis

Author keywords

Apoptosis; Interleukin 1; MSK1; Nitric oxide; p38 MAPK; Pancreatic islet

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BINDING PROTEIN; GAMMA INTERFERON; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR AP 2;

EID: 0035877087     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00605-0     Document Type: Article
Times cited : (89)

References (40)
  • 1
    • 0030005411 scopus 로고    scopus 로고
    • The harmony of the spheres: Inducible nitric oxide synthase and related genes in pancreatic β cells
    • Eizirik D.L., Flodström M., Karlsen E.A., Welsh N. The harmony of the spheres inducible nitric oxide synthase and related genes in pancreatic β cells . Diabetologia. 39:1996;875-890.
    • (1996) Diabetologia , vol.39 , pp. 875-890
    • Eizirik, D.L.1    Flodström, M.2    Karlsen, E.A.3    Welsh, N.4
  • 3
    • 0034456628 scopus 로고    scopus 로고
    • Cytokines induce both necrosis and apoptosis via a common Bcl-2-inhabitable pathway in rat insulin-producing cells
    • Saldeen J. Cytokines induce both necrosis and apoptosis via a common Bcl-2-inhabitable pathway in rat insulin-producing cells. Endocrinology. 141:2000;2003-2010.
    • (2000) Endocrinology , vol.141 , pp. 2003-2010
    • Saldeen, J.1
  • 5
    • 0025685395 scopus 로고
    • Inhibition of insulin secretion by interleukin-1β and tumour necrosis factor-α via an L-arginine-dependent nitric oxide generating mechanism
    • Southern C., Schulster D., Green I.C. Inhibition of insulin secretion by interleukin-1β and tumour necrosis factor-α via an L-arginine-dependent nitric oxide generating mechanism. FEBS Lett. 276:1990;42-44.
    • (1990) FEBS Lett , vol.276 , pp. 42-44
    • Southern, C.1    Schulster, D.2    Green, I.C.3
  • 6
    • 0025833992 scopus 로고
    • Interleukin-1β-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase
    • Welsh N., Eizirik D.L., Bendtzen K., Sandler S. Interleukin-1β-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase. Endocrinology. 129:1991;3167-3173.
    • (1991) Endocrinology , vol.129 , pp. 3167-3173
    • Welsh, N.1    Eizirik, D.L.2    Bendtzen, K.3    Sandler, S.4
  • 7
    • 0026793534 scopus 로고
    • Nitric oxide and cyclic GMP formation induced by interleukin 1β in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction
    • Corbett J.A., Wang J.L., Hughes J.H., Wolf B.A., Sweetland M.A., Lancaster J.R. Jr, McDaniel M.L. Nitric oxide and cyclic GMP formation induced by interleukin 1β in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction. Biochem J. 287:1992;229-235.
    • (1992) Biochem J , vol.287 , pp. 229-235
    • Corbett, J.A.1    Wang, J.L.2    Hughes, J.H.3    Wolf, B.A.4    Sweetland, M.A.5    Lancaster J.R., Jr.6    McDaniel, M.L.7
  • 8
    • 0032579373 scopus 로고    scopus 로고
    • Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic β cells develop insulin-dependent diabetes without insulitis
    • Takamura T., Kato I., Kimura N., Nakazawa T., Yonekura H., Takasawa S., Okamoto H. Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic β cells develop insulin-dependent diabetes without insulitis. J Biol Chem. 273:1998;2493-2496.
    • (1998) J Biol Chem , vol.273 , pp. 2493-2496
    • Takamura, T.1    Kato, I.2    Kimura, N.3    Nakazawa, T.4    Yonekura, H.5    Takasawa, S.6    Okamoto, H.7
  • 9
    • 0030997703 scopus 로고    scopus 로고
    • Interferon-γ increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1
    • Heitmeier M.R., Scarim A.L., Corbett J.A. Interferon-γ increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1. J Biol Chem. 272:1997;13697-13704.
    • (1997) J Biol Chem , vol.272 , pp. 13697-13704
    • Heitmeier, M.R.1    Scarim, A.L.2    Corbett, J.A.3
  • 10
    • 0029932759 scopus 로고    scopus 로고
    • Interleukin-1 β-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F
    • Welsh N. Interleukin-1 β-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F. J Biol Chem. 271:1996;8307-8312.
    • (1996) J Biol Chem , vol.271 , pp. 8307-8312
    • Welsh, N.1
  • 11
    • 0032510838 scopus 로고    scopus 로고
    • Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases
    • Larsen C.M., Wadt K.A., Juhl L.F., Andersen H.U., Karlsen A.E., Su M.S., Seedorf K., Shapiro L., Dinarello C.A., Mandrup-Poulsen T. Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases. J Biol Chem. 273:1998;15294-15300.
    • (1998) J Biol Chem , vol.273 , pp. 15294-15300
    • Larsen, C.M.1    Wadt, K.A.2    Juhl, L.F.3    Andersen, H.U.4    Karlsen, A.E.5    Su, M.S.6    Seedorf, K.7    Shapiro, L.8    Dinarello, C.A.9    Mandrup-Poulsen, T.10
  • 12
    • 0032832969 scopus 로고    scopus 로고
    • Prolonged STAT1 activation is associated with interferon-γ priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans
    • Heitmeier M.R., Scarim A.L., Corbett J.A. Prolonged STAT1 activation is associated with interferon-γ priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans. J Biol Chem. 274:1999;29266-29273.
    • (1999) J Biol Chem , vol.274 , pp. 29266-29273
    • Heitmeier, M.R.1    Scarim, A.L.2    Corbett, J.A.3
  • 13
    • 0030891270 scopus 로고    scopus 로고
    • The interleukin-1 receptor complex and interleukin-1 signal transduction
    • Martin M.U., Falk W. The interleukin-1 receptor complex and interleukin-1 signal transduction. Eur Cytokine Netw. 8:1997;5-17.
    • (1997) Eur Cytokine Netw , vol.8 , pp. 5-17
    • Martin, M.U.1    Falk, W.2
  • 14
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1
    • Malinin N.L., Boldin M.P., Kovalenko A.V., Wallach D. MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1. Nature. 385:1997;540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 16
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso O.A., Chiariello M., Yu J.C., Teramoto H., Crespo P., Xu N., Miki T., Gutkind J.S. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell. 81:1995;1137-1146.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 17
    • 0031437885 scopus 로고    scopus 로고
    • Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-κB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2- And germinal center kinase related-dependent pathway
    • Shi C.S., Kehrl J.H. Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-κB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2- and germinal center kinase related-dependent pathway. J Biol Chem. 272:1997;32102-32107.
    • (1997) J Biol Chem , vol.272 , pp. 32102-32107
    • Shi, C.S.1    Kehrl, J.H.2
  • 18
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z., Dickens M., Raingeaud J., Davis R.J., Greenberg M.E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 270:1995;1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 19
    • 0023882424 scopus 로고
    • Inhibitor of interleukin 1 in normal human urine. Different effects on mouse thymocytes and on a murine T-cell line
    • Svenson M., Bendtzen K. Inhibitor of interleukin 1 in normal human urine. Different effects on mouse thymocytes and on a murine T-cell line. Scand J Immunol. 27:1988;593-599.
    • (1988) Scand J Immunol , vol.27 , pp. 593-599
    • Svenson, M.1    Bendtzen, K.2
  • 20
    • 0018189864 scopus 로고
    • Isolated mouse pancreatic islets in culture: Effects of serum and different culture media on the insulin production of the islets
    • Andersson A. Isolated mouse pancreatic islets in culture effects of serum and different culture media on the insulin production of the islets . Diabetologia. 14:1978;397-404.
    • (1978) Diabetologia , vol.14 , pp. 397-404
    • Andersson, A.1
  • 21
    • 0344766073 scopus 로고    scopus 로고
    • Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages
    • Hortelano S., López-Collazo E., Boscá L. Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages. Br J Pharmacol. 126:1999;1139-1146.
    • (1999) Br J Pharmacol , vol.126 , pp. 1139-1146
    • Hortelano, S.1    López-Collazo, E.2    Boscá, L.3
  • 23
    • 0034523567 scopus 로고    scopus 로고
    • The acid sphingomyelinase inhibitor SR33557 counteracts TNF-α-mediated potentiation of IL-1β-induced NF-κB activation in the insulin-producing cell line RINm5F
    • Saldeen J., Jaffrézzou J.-P., Welsh N. The acid sphingomyelinase inhibitor SR33557 counteracts TNF-α-mediated potentiation of IL-1β-induced NF-κB activation in the insulin-producing cell line RINm5F. Autoimmunity. 32:2000;241-254.
    • (2000) Autoimmunity , vol.32 , pp. 241-254
    • Saldeen, J.1    Jaffrézzou, J.-P.2    Welsh, N.3
  • 24
    • 0032479983 scopus 로고    scopus 로고
    • Mitogen-and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
    • Deak M., Clifton A.D., Lucocq L.M., Alessi D.R. Mitogen-and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J. 17:1998;4426-4441.
    • (1998) EMBO J , vol.17 , pp. 4426-4441
    • Deak, M.1    Clifton, A.D.2    Lucocq, L.M.3    Alessi, D.R.4
  • 26
    • 0034654533 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-simulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages
    • Caivano M., Cohen P. Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-simulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages. J Immunol. 164:2000;3018-3025.
    • (2000) J Immunol , vol.164 , pp. 3018-3025
    • Caivano, M.1    Cohen, P.2
  • 27
    • 0033538513 scopus 로고    scopus 로고
    • Stress-induced simulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner
    • Rolli M., Kotlyarov A., Sakamoto K.M., Gaestel M., Neininger A. Stress-induced simulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner. J Biol Chem. 274:1999;19559-19564.
    • (1999) J Biol Chem , vol.274 , pp. 19559-19564
    • Rolli, M.1    Kotlyarov, A.2    Sakamoto, K.M.3    Gaestel, M.4    Neininger, A.5
  • 29
    • 0032870660 scopus 로고    scopus 로고
    • Structural and functional changes resulting from islet isolation lead to islet cell death
    • Rosenberg L., Wang R., Parskevas S., Maysinger D. Structural and functional changes resulting from islet isolation lead to islet cell death. Surgery. 126:1999;393-398.
    • (1999) Surgery , vol.126 , pp. 393-398
    • Rosenberg, L.1    Wang, R.2    Parskevas, S.3    Maysinger, D.4
  • 30
    • 0032762406 scopus 로고    scopus 로고
    • Distinct roles of JNKs/p38 MAP kinase and ERKs in apoptosis and survival of HCD-57 cells induced by withdrawal or addition of erythropoietin
    • Shan R., Price J.O., Gaarde W.A., Monia B.P., Krantz S.B., Zhao Z.J. Distinct roles of JNKs/p38 MAP kinase and ERKs in apoptosis and survival of HCD-57 cells induced by withdrawal or addition of erythropoietin. Blood. 94:1999;4067-4076.
    • (1999) Blood , vol.94 , pp. 4067-4076
    • Shan, R.1    Price, J.O.2    Gaarde, W.A.3    Monia, B.P.4    Krantz, S.B.5    Zhao, Z.J.6
  • 31
    • 0033600821 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neroplastoma SH-SY5Y cells
    • Oh-hashi K., Maruyama W., Yi H., Takahashi T., Naoi M., Isobe K. Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neroplastoma SH-SY5Y cells. Biochem Biophys Res Commun. 263:1999;504-509.
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 504-509
    • Oh-Hashi, K.1    Maruyama, W.2    Yi, H.3    Takahashi, T.4    Naoi, M.5    Isobe, K.6
  • 32
    • 0033198306 scopus 로고    scopus 로고
    • Regulation of mitogen-activated protein kinases by sphingolipid products in oligodendrocytes
    • Hida H., Nagano S., Takeda M., Soliven B. Regulation of mitogen-activated protein kinases by sphingolipid products in oligodendrocytes. J Neurosci. 19:1999;7458-7467.
    • (1999) J Neurosci , vol.19 , pp. 7458-7467
    • Hida, H.1    Nagano, S.2    Takeda, M.3    Soliven, B.4
  • 33
    • 0032797212 scopus 로고    scopus 로고
    • A dual function for p38 MAP kinase in hematopoietic cells: Involvement in apoptosis and cell activation
    • Birkenkamp K.U., Kokter W.H., Esselink M.T., Jonk L.J., Kruijer W., Vellenga E. A dual function for p38 MAP kinase in hematopoietic cells involvement in apoptosis and cell activation . Leukemia. 13:1999;1037-1045.
    • (1999) Leukemia , vol.13 , pp. 1037-1045
    • Birkenkamp, K.U.1    Kokter, W.H.2    Esselink, M.T.3    Jonk, L.J.4    Kruijer, W.5    Vellenga, E.6
  • 35
    • 0033949313 scopus 로고    scopus 로고
    • Cytokines induce apoptosis in β-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-)
    • Liu D., Pavlovic D., Chen M.-C., Flodström M., Sandler S., Eizirik D.L. Cytokines induce apoptosis in β-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-). Diabetes. 49:2000;1116-1122.
    • (2000) Diabetes , vol.49 , pp. 1116-1122
    • Liu, D.1    Pavlovic, D.2    Chen, M.-C.3    Flodström, M.4    Sandler, S.5    Eizirik, D.L.6
  • 36
    • 0033602849 scopus 로고    scopus 로고
    • Modulation of nitric oxide-induced apoptotic death of HL-60 cells by protein kinase C and protein kinase A through mitogen-activated protein kinases and CPP32-like protease pathways
    • Jun C.D., Pae H.O., Kwak H.J., Yoo J.C., Choi B.M., Oh C.D., Chun J.S., Paik S.G., Park Y.H., Chung H.T. Modulation of nitric oxide-induced apoptotic death of HL-60 cells by protein kinase C and protein kinase A through mitogen-activated protein kinases and CPP32-like protease pathways. Cell Immunol. 194:1999;36-46.
    • (1999) Cell Immunol , vol.194 , pp. 36-46
    • Jun, C.D.1    Pae, H.O.2    Kwak, H.J.3    Yoo, J.C.4    Choi, B.M.5    Oh, C.D.6    Chun, J.S.7    Paik, S.G.8    Park, Y.H.9    Chung, H.T.10
  • 37
    • 0033559903 scopus 로고    scopus 로고
    • Overexpression of protein kinase C isoforms protects RAW264.7 macrophages from nitric oxide-induced apoptosis: Involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase, and CPP-32 protease pathways
    • Jun C.D., Oh C.D., Kwak H.J., Pae H.O., Yoo J.C., Choi B.M., Chun J.S., Park R.K., Chung H.T. Overexpression of protein kinase C isoforms protects RAW264.7 macrophages from nitric oxide-induced apoptosis involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase, and CPP-32 protease pathways . J Immunol. 162:1999;3395-3401.
    • (1999) J Immunol , vol.162 , pp. 3395-3401
    • Jun, C.D.1    Oh, C.D.2    Kwak, H.J.3    Pae, H.O.4    Yoo, J.C.5    Choi, B.M.6    Chun, J.S.7    Park, R.K.8    Chung, H.T.9
  • 38
    • 0033520376 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase is involved in Fas ligand expression
    • Hsu S.C., Gavrilin M.A., Tsai M.H., Han J., Lai M.Z. p38 mitogen-activated protein kinase is involved in Fas ligand expression. J Biol Chem. 274:1999;25769-25776.
    • (1999) J Biol Chem , vol.274 , pp. 25769-25776
    • Hsu, S.C.1    Gavrilin, M.A.2    Tsai, M.H.3    Han, J.4    Lai, M.Z.5
  • 39
    • 0033617288 scopus 로고    scopus 로고
    • P38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389
    • Huang C., Ma W.Y., Maxiner A., Sun Y., Dong Z. p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389. J Biol Chem. 274:1999;12229-12235.
    • (1999) J Biol Chem , vol.274 , pp. 12229-12235
    • Huang, C.1    Ma, W.Y.2    Maxiner, A.3    Sun, Y.4    Dong, Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.