-
1
-
-
0021777067
-
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited
-
Kloppel G, Lohr M, Habich K, Oberholzer M, Heitz PU: Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited. Surv Synth Pathol Res 4:110-125, 1985
-
(1985)
Surv Synth Pathol Res
, vol.4
, pp. 110-125
-
-
Kloppel, G.1
Lohr, M.2
Habich, K.3
Oberholzer, M.4
Heitz, P.U.5
-
2
-
-
0029056128
-
Insulin deficiency and insulin resistance in the pathogenesis of NIDDM: Is a divorce possible?
-
Cerasi E: Insulin deficiency and insulin resistance in the pathogenesis of NIDDM: is a divorce possible? Diabetologia 38:992-997, 1995
-
(1995)
Diabetologia
, vol.38
, pp. 992-997
-
-
Cerasi, E.1
-
3
-
-
0028229508
-
Insulin resistance or insulin deficiency: Which is the primary cause of NIDDM?
-
Taylor SI, Accili D, Imai Y: Insulin resistance or insulin deficiency: which is the primary cause of NIDDM? Diabetes 43:735-740, 1994
-
(1994)
Diabetes
, vol.43
, pp. 735-740
-
-
Taylor, S.I.1
Accili, D.2
Imai, Y.3
-
4
-
-
0034457378
-
Insulin resistance is not necessarily an essential component of type 2 diabetes
-
Gerich JE: Insulin resistance is not necessarily an essential component of type 2 diabetes. J Clin Endocrinol Metab 85:2113-2115, 2000
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2113-2115
-
-
Gerich, J.E.1
-
5
-
-
0034042959
-
Islet growth and development in the adult
-
Bonner-Weir S: Islet growth and development in the adult. J Mol Endocrinol 24:297-302, 2000
-
(2000)
J Mol Endocrinol
, vol.24
, pp. 297-302
-
-
Bonner-Weir, S.1
-
6
-
-
0030596338
-
Seminars in Medicine of the Beth Israel Hospital, Boston: Non-insulin-dependent diabetes mellitus: a genetically programmed failure of the beta cell to compensate for insulin resistance
-
Polonsky KS, Sturis J, Bell GI: Seminars in Medicine of the Beth Israel Hospital, Boston: non-insulin-dependent diabetes mellitus: a genetically programmed failure of the beta cell to compensate for insulin resistance. N Engl J Med 334:777-783, 1998
-
(1998)
N Engl J Med
, vol.334
, pp. 777-783
-
-
Polonsky, K.S.1
Sturis, J.2
Bell, G.I.3
-
7
-
-
0031913829
-
Role of apoptosis in failure of β-cell mass compensation for insulin resistance and β-cell defects in the male Zucker diabetic fatty rat
-
Pick A, Clark J, Kubstrup C, Levisetti M, Pugh W, Bonner-Weir S, Polonsky KS: Role of apoptosis in failure of β-cell mass compensation for insulin resistance and β-cell defects in the male Zucker diabetic fatty rat. Diabetes 47:358-364, 1998
-
(1998)
Diabetes
, vol.47
, pp. 358-364
-
-
Pick, A.1
Clark, J.2
Kubstrup, C.3
Levisetti, M.4
Pugh, W.5
Bonner-Weir, S.6
Polonsky, K.S.7
-
8
-
-
0033034807
-
Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes
-
Donath MY, Gross DJ, Cerasi E, Kaiser N: Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. Diabetes 48:738-744, 1999
-
(1999)
Diabetes
, vol.48
, pp. 738-744
-
-
Donath, M.Y.1
Gross, D.J.2
Cerasi, E.3
Kaiser, N.4
-
9
-
-
0029797603
-
Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program
-
Hoorens A, Van, DC, Kloppel G, Pipeleers D: Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program. J Clin Invest 98:1568-1574, 1996
-
(1996)
J Clin Invest
, vol.98
, pp. 1568-1574
-
-
Hoorens, A.1
Van, D.C.2
Kloppel, G.3
Pipeleers, D.4
-
10
-
-
0024508097
-
Compensatory growth of pancreatic β-cells in adult rats after short-term glucose infusion
-
Bonner-Weir S, Deery D, Leahy JL, Weir GC: Compensatory growth of pancreatic β-cells in adult rats after short-term glucose infusion. Diabetes 38:49-53, 1989
-
(1989)
Diabetes
, vol.38
, pp. 49-53
-
-
Bonner-Weir, S.1
Deery, D.2
Leahy, J.L.3
Weir, G.C.4
-
11
-
-
0030937468
-
Apoptosis is the mode of β-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse
-
O'Brien BA, Harmon BV, Cameron DP, Allan DJ: Apoptosis is the mode of β-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse. Diabetes 46:750-757, 1997
-
(1997)
Diabetes
, vol.46
, pp. 750-757
-
-
O'Brien, B.A.1
Harmon, B.V.2
Cameron, D.P.3
Allan, D.J.4
-
12
-
-
0031030653
-
Beta cell apoptosis in T cell-mediated autoimmune diabetes
-
Kurrer MO, Pakala SV, Hanson HL, Katz JD: Beta cell apoptosis in T cell-mediated autoimmune diabetes. Proc Natl Acad Sci U S A 94:213-218, 1997
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 213-218
-
-
Kurrer, M.O.1
Pakala, S.V.2
Hanson, H.L.3
Katz, J.D.4
-
13
-
-
0031739726
-
Apoptosis and beta-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes
-
Augstein P, Elefanty AG, Allison J, Harrison LC: Apoptosis and beta-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes. Diabetologia 41:1381-1388, 1998
-
(1998)
Diabetologia
, vol.41
, pp. 1381-1388
-
-
Augstein, P.1
Elefanty, A.G.2
Allison, J.3
Harrison, L.C.4
-
14
-
-
0034641898
-
CD95's deadly mission in the immune system
-
Krammer PH: CD95's deadly mission in the immune system (Review). Nature 407:789-795, 2000
-
(2000)
Nature
, vol.407
, pp. 789-795
-
-
Krammer, P.H.1
-
15
-
-
0029856723
-
Mouse islet cell lysis mediated by interleukin-1-induced Fas
-
Yamada K, Takane-Gyotoku N, Yuan X, Ichikawa F, Inada C, Nonaka K: Mouse islet cell lysis mediated by interleukin-1-induced Fas. Diabetologia 39:1306-1312, 1996
-
(1996)
Diabetologia
, vol.39
, pp. 1306-1312
-
-
Yamada, K.1
Takane-Gyotoku, N.2
Yuan, X.3
Ichikawa, F.4
Inada, C.5
Nonaka, K.6
-
16
-
-
0029560147
-
Expression of apoptosis-inducing CD95 (Fas/Apo-1) on human beta-cells sorted by flow-cytometry and cultured in vitro
-
Stassi G, Todaro M, Richiusa P, Giordano M, Mattina A, Sbriglia MS, Lo MA, Buscemi G, Galluzzo A, Giordano C: Expression of apoptosis-inducing CD95 (Fas/Apo-1) on human beta-cells sorted by flow-cytometry and cultured in vitro. Transplant Proc 27:3271-3275, 1995
-
(1995)
Transplant Proc
, vol.27
, pp. 3271-3275
-
-
Stassi, G.1
Todaro, M.2
Richiusa, P.3
Giordano, M.4
Mattina, A.5
Sbriglia, M.S.6
Ma, L.7
Buscemi, G.8
Galluzzo, A.9
Giordano, C.10
-
17
-
-
0031897507
-
Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1β and Fas ligation
-
Loweth AC, Williams GT, James RF, Scarpello JH, Morgan NG: Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1β and Fas ligation. Diabetes 47:727-732, 1998
-
(1998)
Diabetes
, vol.47
, pp. 727-732
-
-
Loweth, A.C.1
Williams, G.T.2
James, R.F.3
Scarpello, J.H.4
Morgan, N.G.5
-
18
-
-
0030890721
-
The role of Fas in autoimmune diabetes
-
Chervonsky AV, Wang Y, Wong FS, Visintin I, Flavell RA, Janeway CA Jr, Matis LA: The role of Fas in autoimmune diabetes. Cell 89:17-24, 1997
-
(1997)
Cell
, vol.89
, pp. 17-24
-
-
Chervonsky, A.V.1
Wang, Y.2
Wong, F.S.3
Visintin, I.4
Flavell, R.A.5
Janeway C.A., Jr.6
Matis, L.A.7
-
19
-
-
0030800122
-
Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice
-
Itoh N, Imagawa A, Hanafusa T, Waguri M, Yamamoto K, Iwahashi H, Moriwaki M, Nakajima H, Miyagawa J, Namba M, Makino S, Nagata S, Kono N, Matsuzawa Y: Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice. J Exp Med 186:613-618, 1997
-
(1997)
J Exp Med
, vol.186
, pp. 613-618
-
-
Itoh, N.1
Imagawa, A.2
Hanafusa, T.3
Waguri, M.4
Yamamoto, K.5
Iwahashi, H.6
Moriwaki, M.7
Nakajima, H.8
Miyagawa, J.9
Namba, M.10
Makino, S.11
Nagata, S.12
Kono, N.13
Matsuzawa, Y.14
-
20
-
-
0032506224
-
Mechanisms of beta cell death in diabetes: A minor role for CD95
-
Allison J, Strasser A: Mechanisms of beta cell death in diabetes: a minor role for CD95. Proc Natl Acad Sci U S A 95:13818-13822, 1998
-
(1998)
Proc Natl Acad Sci u s a
, vol.95
, pp. 13818-13822
-
-
Allison, J.1
Strasser, A.2
-
21
-
-
0033178741
-
Evidence that beta cell death in the nonobese diabetic mouse is Fas independent
-
Thomas HE, Darwiche R, Corbett JA, Kay TW: Evidence that beta cell death in the nonobese diabetic mouse is Fas independent. J Immunol 163:1562-1569, 1999
-
(1999)
J Immunol
, vol.163
, pp. 1562-1569
-
-
Thomas, H.E.1
Darwiche, R.2
Corbett, J.A.3
Kay, T.W.4
-
22
-
-
0030988289
-
Improved human islet isolation using a new enzyme blend, liberase
-
Linetsky E, Bottino R, Lehmann R, Alejandro R, Inverardi L, Ricordi C: Improved human islet isolation using a new enzyme blend, liberase. Diabetes 46:1120-1123, 1997
-
(1997)
Diabetes
, vol.46
, pp. 1120-1123
-
-
Linetsky, E.1
Bottino, R.2
Lehmann, R.3
Alejandro, R.4
Inverardi, L.5
Ricordi, C.6
-
23
-
-
0026091234
-
Monolayer culture of adult rat pancreatic islets on extracellular matrix: Modulation of B-cell function by chronic exposure to high glucose
-
Kaiser N, Corcos AP, Sarel I, Cerasi E: Monolayer culture of adult rat pancreatic islets on extracellular matrix: modulation of B-cell function by chronic exposure to high glucose. Endocrinology 129:2067-2076, 1991
-
(1991)
Endocrinology
, vol.129
, pp. 2067-2076
-
-
Kaiser, N.1
Corcos, A.P.2
Sarel, I.3
Cerasi, E.4
-
24
-
-
0344258475
-
Impaired β-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose
-
Marshak S, Leibowitz G, Bertuzzi F, Socci C, Kaiser N, Gross DJ, Cerasi E, Melloul D: Impaired β-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose. Diabetes 48:1230-1236, 1999
-
(1999)
Diabetes
, vol.48
, pp. 1230-1236
-
-
Marshak, S.1
Leibowitz, G.2
Bertuzzi, F.3
Socci, C.4
Kaiser, N.5
Gross, D.J.6
Cerasi, E.7
Melloul, D.8
-
25
-
-
0030942255
-
Proliferation and differentiation in the human fetal endocrine pancreas
-
Bouwens L, Lu WG, De KR: Proliferation and differentiation in the human fetal endocrine pancreas. Diabetologia 40:398-404, 1997
-
(1997)
Diabetologia
, vol.40
, pp. 398-404
-
-
Bouwens, L.1
Lu, W.G.2
De, K.R.3
-
26
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavrieli Y, Sherman Y, Ben-Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501, 1992
-
(1992)
J Cell Biol
, vol.119
, pp. 493-501
-
-
Gavrieli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
27
-
-
0029073752
-
Fas/APO-1 gene transfer for human malignant glioma
-
Weller M, Malipiero U, Rensing-Ehl A, Barr PJ, Fontana A: Fas/APO-1 gene transfer for human malignant glioma. Cancer Res 55:2936-2944, 1995
-
(1995)
Cancer Res
, vol.55
, pp. 2936-2944
-
-
Weller, M.1
Malipiero, U.2
Rensing-Ehl, A.3
Barr, P.J.4
Fontana, A.5
-
28
-
-
0032550366
-
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
-
Schneider P, Holler N, Bodmer JL, Hahne M, Frei K, Fontana A, Tschopp J: Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med 187:1205-1213, 1998
-
(1998)
J Exp Med
, vol.187
, pp. 1205-1213
-
-
Schneider, P.1
Holler, N.2
Bodmer, J.L.3
Hahne, M.4
Frei, K.5
Fontana, A.6
Tschopp, J.7
-
29
-
-
0035156817
-
Distinct effects of saturated and monounsaturated fatty acids on β-cell turnover and function
-
Maedler K, Spinas GA, Dyntar D, Moritz W, Kaiser N, Donath MY: Distinct effects of saturated and monounsaturated fatty acids on β-cell turnover and function. Diabetes 50:69-76, 2001
-
(2001)
Diabetes
, vol.50
, pp. 69-76
-
-
Maedler, K.1
Spinas, G.A.2
Dyntar, D.3
Moritz, W.4
Kaiser, N.5
Donath, M.Y.6
-
30
-
-
0032750928
-
Fas and Fas ligand expression in inflamed islets in pancreas sections of patients with recent-onset type I diabetes mellitus
-
Moriwaki M, Itoh N, Miyagawa J, Yamamoto K, Imagawa A, Yamagata K, Iwahashi H, Nakajima H, Namba M, Nagata S, Hanafusa T, Matsuzawa Y: Fas and Fas ligand expression in inflamed islets in pancreas sections of patients with recent-onset type I diabetes mellitus. Diabetologia 42:1332-1340, 1999
-
(1999)
Diabetologia
, vol.42
, pp. 1332-1340
-
-
Moriwaki, M.1
Itoh, N.2
Miyagawa, J.3
Yamamoto, K.4
Imagawa, A.5
Yamagata, K.6
Iwahashi, H.7
Nakajima, H.8
Namba, M.9
Nagata, S.10
Hanafusa, T.11
Matsuzawa, Y.12
-
31
-
-
0030731917
-
Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus
-
Stassi G, De Maria R, Trucco G, Rudert W, Testi R, Galluzzo A, Giordano C, Trucco M: Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus. J Exp Med 186:1193-1200, 1997
-
(1997)
J Exp Med
, vol.186
, pp. 1193-1200
-
-
Stassi, G.1
De Maria, R.2
Trucco, G.3
Rudert, W.4
Testi, R.5
Galluzzo, A.6
Giordano, C.7
Trucco, M.8
-
32
-
-
0032080637
-
Technical note: Aberrant detection of cell surface Fas ligand with anti-peptide antibodies
-
Smith D, Sieg S, Kaplan D: Technical note: aberrant detection of cell surface Fas ligand with anti-peptide antibodies. J Immunol 160:4159-4160, 1998
-
(1998)
J Immunol
, vol.160
, pp. 4159-4160
-
-
Smith, D.1
Sieg, S.2
Kaplan, D.3
-
33
-
-
0034615555
-
Caspases-controlling intracellular signals by protease zymogen activation
-
Stennicke HR, Salvesen GS: Caspases-controlling intracellular signals by protease zymogen activation. Biochim Biophys Acta 1477:299-306, 2000
-
(2000)
Biochim Biophys Acta
, vol.1477
, pp. 299-306
-
-
Stennicke, H.R.1
Salvesen, G.S.2
-
34
-
-
0032509446
-
Glucose and tolbutamide induce apoptosis in pancreatic beta-cells: A process dependent on intracellular Ca2+ concentration
-
Efanova IB, Zaitsev SV, Zhivotovsky B, Kohler M, Efendic S, Orrenius S, Berggren PO: Glucose and tolbutamide induce apoptosis in pancreatic beta-cells: a process dependent on intracellular Ca2+ concentration. J Biol Chem 273:33501-33507, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 33501-33507
-
-
Efanova, I.B.1
Zaitsev, S.V.2
Zhivotovsky, B.3
Kohler, M.4
Efendic, S.5
Orrenius, S.6
Berggren, P.O.7
-
35
-
-
0033781823
-
Apoptosis and occurrence of Bcl-2, Bak, Bax, Fas and FasL in the developing and adult rat endocrine pancreas
-
Berl
-
Hanke J: Apoptosis and occurrence of Bcl-2, Bak, Bax, Fas and FasL in the developing and adult rat endocrine pancreas. Anat Embryol (Berl) 202: 303-312, 2000
-
(2000)
Anat Embryol
, vol.202
, pp. 303-312
-
-
Hanke, J.1
-
36
-
-
0024213009
-
Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: Quantitative changes in the pancreas in type 2 diabetes
-
Clark A, Wells CA, Buley ID, Cruickshank JK, Vanhegan RI, Matthews DR, Cooper GJ, Holman RR, Turner RC: Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes. Diabetes Res 9:151-159, 1988
-
(1988)
Diabetes Res
, vol.9
, pp. 151-159
-
-
Clark, A.1
Wells, C.A.2
Buley, I.D.3
Cruickshank, J.K.4
Vanhegan, R.I.5
Matthews, D.R.6
Cooper, G.J.7
Holman, R.R.8
Turner, R.C.9
-
37
-
-
0018641183
-
Differential volumetry of A, B and D cells in the pancreatic islets of diabetic and nondiabetic subjects
-
Saito K, Yaginuma N, Takahashi T: Differential volumetry of A, B and D cells in the pancreatic islets of diabetic and nondiabetic subjects. Tohoku J Exp Med 129:273-283, 1979
-
(1979)
Tohoku J Exp Med
, vol.129
, pp. 273-283
-
-
Saito, K.1
Yaginuma, N.2
Takahashi, T.3
|