-
1
-
-
0036745064
-
Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis
-
Aganna E., Martinon F., Hawkins P.N., Ross J.B., Swan D.C., Booth D.R., Lachmann H.J., Bybee A., Gaudet R., Woo P., et al. Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum. 46 (2002) 2445-2452
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 2445-2452
-
-
Aganna, E.1
Martinon, F.2
Hawkins, P.N.3
Ross, J.B.4
Swan, D.C.5
Booth, D.R.6
Lachmann, H.J.7
Bybee, A.8
Gaudet, R.9
Woo, P.10
-
2
-
-
0033952638
-
The role of IL-18 in innate immunity
-
Akira S. The role of IL-18 in innate immunity. Curr. Opin. Immunol. 12 (2000) 59-63
-
(2000)
Curr. Opin. Immunol.
, vol.12
, pp. 59-63
-
-
Akira, S.1
-
3
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S., and Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 4 (2004) 499-511
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
4
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
Alexopoulou L., Holt A.C., Medzhitov R., and Flavell A. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413 (2001) 732-738
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, A.4
-
5
-
-
0022189558
-
Establishment of dorsal-ventral polarity in the Drosophila embryo: The induction of polarity by the Toll gene product
-
Anderson K.V., Bokla L., and Nusslein-Volhard C. Establishment of dorsal-ventral polarity in the Drosophila embryo: The induction of polarity by the Toll gene product. Cell 42 (1985) 791-798
-
(1985)
Cell
, vol.42
, pp. 791-798
-
-
Anderson, K.V.1
Bokla, L.2
Nusslein-Volhard, C.3
-
6
-
-
0022230197
-
Establishment of dorsal-ventral polarity in the Drosophila embryo: Genetic studies on the role of the Toll gene product
-
Anderson K.V., Jurgens G., and Nusslein-Volhard C. Establishment of dorsal-ventral polarity in the Drosophila embryo: Genetic studies on the role of the Toll gene product. Cell 42 (1985) 779-789
-
(1985)
Cell
, vol.42
, pp. 779-789
-
-
Anderson, K.V.1
Jurgens, G.2
Nusslein-Volhard, C.3
-
7
-
-
0344872725
-
Identification of a truncated IL-18Rβ mRNA: A putative regulator of IL-18 expressed in rat brain
-
Andre R., Wheeler R.D., Collins P.D., Luheshi G.N., Pickering-Brown S., Kimber I., Rothwell N.J., and Pinteaux E. Identification of a truncated IL-18Rβ mRNA: A putative regulator of IL-18 expressed in rat brain. J. Neuroimmunol. 145 (2003) 40-45
-
(2003)
J. Neuroimmunol.
, vol.145
, pp. 40-45
-
-
Andre, R.1
Wheeler, R.D.2
Collins, P.D.3
Luheshi, G.N.4
Pickering-Brown, S.5
Kimber, I.6
Rothwell, N.J.7
Pinteaux, E.8
-
8
-
-
27144540463
-
Are innate immune signaling pathways in plants and animals conserved?
-
Ausubel F.M. Are innate immune signaling pathways in plants and animals conserved?. Nat. Immunol. 6 (2005) 973-979
-
(2005)
Nat. Immunol.
, vol.6
, pp. 973-979
-
-
Ausubel, F.M.1
-
10
-
-
0034631775
-
Characterization of an IL-1 receptor from Asterias forbesi coelomocytes
-
Beck G., Ellis T.W., and Truong N. Characterization of an IL-1 receptor from Asterias forbesi coelomocytes. Cell. Immunol. 203 (2000) 66-73
-
(2000)
Cell. Immunol.
, vol.203
, pp. 66-73
-
-
Beck, G.1
Ellis, T.W.2
Truong, N.3
-
11
-
-
1442275001
-
Crohn's disease, mycobacteria, and NOD2
-
Behr M.A., Semret M., Poon A., and Schurr E. Crohn's disease, mycobacteria, and NOD2. Lancet Infect. Dis. 4 (2004) 136-137
-
(2004)
Lancet Infect. Dis.
, vol.4
, pp. 136-137
-
-
Behr, M.A.1
Semret, M.2
Poon, A.3
Schurr, E.4
-
12
-
-
0036533635
-
The first cytokine sequence within cartilaginous fish: IL-1β in the small spotted catshark (Scyliorhinus canicula)
-
Bird S., Wang T., Zou J., Cunningham C., and Secombes C.J. The first cytokine sequence within cartilaginous fish: IL-1β in the small spotted catshark (Scyliorhinus canicula). J. Immunol. 168 (2002) 3329-3340
-
(2002)
J. Immunol.
, vol.168
, pp. 3329-3340
-
-
Bird, S.1
Wang, T.2
Zou, J.3
Cunningham, C.4
Secombes, C.J.5
-
14
-
-
0028788688
-
Mapping of receptor binding sites on IL-1β by reconstruction of IL-1ra-like domains
-
Boraschi D., Bossù P., Ruggiero P., Tagliabue A., Bertini R., Macchia G., Gasbarro C., Pellegrini L., Melillo G., Ulisse E., Visconti U., Bizzarri C., et al. Mapping of receptor binding sites on IL-1β by reconstruction of IL-1ra-like domains. J. Immunol. 155 (1995) 4719-4725
-
(1995)
J. Immunol.
, vol.155
, pp. 4719-4725
-
-
Boraschi, D.1
Bossù, P.2
Ruggiero, P.3
Tagliabue, A.4
Bertini, R.5
Macchia, G.6
Gasbarro, C.7
Pellegrini, L.8
Melillo, G.9
Ulisse, E.10
Visconti, U.11
Bizzarri, C.12
-
15
-
-
0032491599
-
Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling
-
Born T.L., Thomassen E., Bird T.A., and Sims J.E. Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling. J. Biol. Chem. 273 (1998) 29445-29450
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29445-29450
-
-
Born, T.L.1
Thomassen, E.2
Bird, T.A.3
Sims, J.E.4
-
16
-
-
0034730618
-
Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on signaling
-
Born T.L., Smith D.E., Garka K.E., Renshaw B.R., Bertles J.S., and Sims J.E. Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on signaling. J. Biol. Chem. 275 (2000) 29946-29954
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29946-29954
-
-
Born, T.L.1
Smith, D.E.2
Garka, K.E.3
Renshaw, B.R.4
Bertles, J.S.5
Sims, J.E.6
-
17
-
-
0028789085
-
II impairs responsiveness of human keratinocytes to IL-1
-
II impairs responsiveness of human keratinocytes to IL-1. Am. J. Pathol. 147 (1995) 1852-1861
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 1852-1861
-
-
Bossù, P.1
Visconti, U.2
Ruggiero, P.3
Macchia, G.4
Muda, M.5
Bertini, R.6
Bizzarri, C.7
Colagrande, A.8
Sabbatini, V.9
Maurizi, G.10
Del Grosso, E.11
Tagliabue, A.12
-
18
-
-
10744222448
-
IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease
-
Bossù P., Neumann D., Del Giudice E., Ciaramella A., Gloaguen I., Fantuzzi G., Dinarello C.A., Di Carlo E., Musiani P., Meroni P.L., Caselli G., Ruggiero P., et al. IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease. Proc. Natl. Acad. Sci. USA 100 (2003) 14181-14186
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14181-14186
-
-
Bossù, P.1
Neumann, D.2
Del Giudice, E.3
Ciaramella, A.4
Gloaguen, I.5
Fantuzzi, G.6
Dinarello, C.A.7
Di Carlo, E.8
Musiani, P.9
Meroni, P.L.10
Caselli, G.11
Ruggiero, P.12
-
19
-
-
0033861419
-
The interleukin-1 receptor/Toll-like receptor superfamily: Signal generators for pro-inflammatory interleukins and microbial products
-
Bowie A., and O'Neill L.A. The interleukin-1 receptor/Toll-like receptor superfamily: Signal generators for pro-inflammatory interleukins and microbial products. J. Leukoc. Biol. 67 (2000) 508-514
-
(2000)
J. Leukoc. Biol.
, vol.67
, pp. 508-514
-
-
Bowie, A.1
O'Neill, L.A.2
-
20
-
-
0035997488
-
Serum interleukin 18 and interleukin 18 binding protein in rheumatoid arthritis
-
Bresnihan B., Roux-Lombard P., Murphy E., Kane D., FitzGerald O., and Dayer J.M. Serum interleukin 18 and interleukin 18 binding protein in rheumatoid arthritis. Ann. Rheum. Dis. 61 (2002) 726-729
-
(2002)
Ann. Rheum. Dis.
, vol.61
, pp. 726-729
-
-
Bresnihan, B.1
Roux-Lombard, P.2
Murphy, E.3
Kane, D.4
FitzGerald, O.5
Dayer, J.M.6
-
21
-
-
2942721674
-
ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance
-
Brint E.K., Xu D., Liu H., Dunne A., McKenzie A.N., O'Neill L.A., and Liew F.Y. ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat. Immunol. 5 (2004) 373-379
-
(2004)
Nat. Immunol.
, vol.5
, pp. 373-379
-
-
Brint, E.K.1
Xu, D.2
Liu, H.3
Dunne, A.4
McKenzie, A.N.5
O'Neill, L.A.6
Liew, F.Y.7
-
22
-
-
0037109051
-
A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity
-
Bufler P., Azam T., Gamboni-Robertson F., Reznikov L.L., Kumar S., Dinarello C.A., and Kim S.H. A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity. Proc. Natl. Acad. Sci. USA 99 (2002) 13723-13728
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13723-13728
-
-
Bufler, P.1
Azam, T.2
Gamboni-Robertson, F.3
Reznikov, L.L.4
Kumar, S.5
Dinarello, C.A.6
Kim, S.H.7
-
23
-
-
0032819848
-
A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation
-
Carrié A., Jun L., Bienvenu T., Vinet M.C., McDonell N., Couvert P., Zemni R., Cardona A., Van Buggenhout G., Frints S., Hamel B., Moraine C., et al. A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation. Nat. Genet. 23 (1999) 25-31
-
(1999)
Nat. Genet.
, vol.23
, pp. 25-31
-
-
Carrié, A.1
Jun, L.2
Bienvenu, T.3
Vinet, M.C.4
McDonell, N.5
Couvert, P.6
Zemni, R.7
Cardona, A.8
Van Buggenhout, G.9
Frints, S.10
Hamel, B.11
Moraine, C.12
-
24
-
-
0035876314
-
Model of interaction of the IL-1 receptor accessory protein IL-1RAcP with the IL-1β/IL-1R(I) complex
-
Casadio R., Frigimelica E., Bossù P., Neumann D., Martin M.U., Tagliabue A., and Boraschi D. Model of interaction of the IL-1 receptor accessory protein IL-1RAcP with the IL-1β/IL-1R(I) complex. FEBS Lett. 499 (2001) 65-68
-
(2001)
FEBS Lett.
, vol.499
, pp. 65-68
-
-
Casadio, R.1
Frigimelica, E.2
Bossù, P.3
Neumann, D.4
Martin, M.U.5
Tagliabue, A.6
Boraschi, D.7
-
25
-
-
0041827164
-
Nods, Nalps and Naip: Intracellular regulators of bacterial-induced inflammation
-
Chamaillard M., Girardin S.E., Viala J., and Philpott D.J. Nods, Nalps and Naip: Intracellular regulators of bacterial-induced inflammation. Cell. Microbiol. 5 (2003) 581-592
-
(2003)
Cell. Microbiol.
, vol.5
, pp. 581-592
-
-
Chamaillard, M.1
Girardin, S.E.2
Viala, J.3
Philpott, D.J.4
-
26
-
-
0034457684
-
Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9
-
Chuang T.H., and Ulevitch R.J. Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9. Eur. Cytokine Netw. 11 (2000) 372-378
-
(2000)
Eur. Cytokine Netw.
, vol.11
, pp. 372-378
-
-
Chuang, T.H.1
Ulevitch, R.J.2
-
27
-
-
0027181936
-
Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4
-
Colotta F., Re F., Muzio M., Bertini R., Polentarutti N., Sironi M., Giri J.G., Dower S.K., Sims J.E., and Mantovani A. Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4. Science 261 (1993) 472-475
-
(1993)
Science
, vol.261
, pp. 472-475
-
-
Colotta, F.1
Re, F.2
Muzio, M.3
Bertini, R.4
Polentarutti, N.5
Sironi, M.6
Giri, J.G.7
Dower, S.K.8
Sims, J.E.9
Mantovani, A.10
-
28
-
-
0028004236
-
The type II 'decoy' receptor: A novel regulatory pathway for interleukin 1
-
Colotta F., Dower S.K., Sims J.E., and Mantovani A. The type II 'decoy' receptor: A novel regulatory pathway for interleukin 1. Immunol. Today 15 (1994) 562-566
-
(1994)
Immunol. Today
, vol.15
, pp. 562-566
-
-
Colotta, F.1
Dower, S.K.2
Sims, J.E.3
Mantovani, A.4
-
29
-
-
0033523665
-
Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses
-
Coyle A.J., Lloyd C., Tian J., Nguyen T., Erikkson C., Wang L., Ottoson P., Persson P., Delaney T., Lehar S., Lin S., Poisson L., et al. Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses. J. Exp. Med. 190 (1999) 895-902
-
(1999)
J. Exp. Med.
, vol.190
, pp. 895-902
-
-
Coyle, A.J.1
Lloyd, C.2
Tian, J.3
Nguyen, T.4
Erikkson, C.5
Wang, L.6
Ottoson, P.7
Persson, P.8
Delaney, T.9
Lehar, S.10
Lin, S.11
Poisson, L.12
-
30
-
-
0345735829
-
Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding
-
Cui X., Rouhani F.N., Hawari F., and Levine S.J. Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding. J. Immunol. 171 (2003) 6814-6819
-
(2003)
J. Immunol.
, vol.171
, pp. 6814-6819
-
-
Cui, X.1
Rouhani, F.N.2
Hawari, F.3
Levine, S.J.4
-
31
-
-
0032533814
-
IL-1 receptor accessory protein is an essential component of the IL-1 receptor
-
Cullinan E.B., Kwee L., Nunes P., Shuster D.J., Ju G., McIntyre K.W., Chizzonite R.A., and Labow M.A. IL-1 receptor accessory protein is an essential component of the IL-1 receptor. J. Immunol. 161 (1998) 5614-5620
-
(1998)
J. Immunol.
, vol.161
, pp. 5614-5620
-
-
Cullinan, E.B.1
Kwee, L.2
Nunes, P.3
Shuster, D.J.4
Ju, G.5
McIntyre, K.W.6
Chizzonite, R.A.7
Labow, M.A.8
-
32
-
-
0034326652
-
IL-18 receptors, their role in ligand binding and function: Anti-IL-1RAcPL antibody, a potent antagonist of IL-18
-
Debets R., Timans J.C., Churakowa T., Zurawski S., de Waal Malefyt R., Moore K.W., Abrams J.S., O'Garra A., Bazan J.F., and Kastelein R.A. IL-18 receptors, their role in ligand binding and function: Anti-IL-1RAcPL antibody, a potent antagonist of IL-18. J. Immunol. 165 (2000) 4950-4956
-
(2000)
J. Immunol.
, vol.165
, pp. 4950-4956
-
-
Debets, R.1
Timans, J.C.2
Churakowa, T.3
Zurawski, S.4
de Waal Malefyt, R.5
Moore, K.W.6
Abrams, J.S.7
O'Garra, A.8
Bazan, J.F.9
Kastelein, R.A.10
-
33
-
-
0035422660
-
Two novel IL-1 family members, IL-1δ and IL-1ε, function as an antagonist and agonist of NF-κB activation through the orphan IL-1 receptor-related protein 2
-
Debets R., Timans J.C., Homey B., Zurawski S., Sana T.R., Lo S., Wagner J., Edwards G., Clifford T., Menon S., Bazan J.F., and Kastelein R.A. Two novel IL-1 family members, IL-1δ and IL-1ε, function as an antagonist and agonist of NF-κB activation through the orphan IL-1 receptor-related protein 2. J. Immunol. 167 (2001) 1440-1446
-
(2001)
J. Immunol.
, vol.167
, pp. 1440-1446
-
-
Debets, R.1
Timans, J.C.2
Homey, B.3
Zurawski, S.4
Sana, T.R.5
Lo, S.6
Wagner, J.7
Edwards, G.8
Clifford, T.9
Menon, S.10
Bazan, J.F.11
Kastelein, R.A.12
-
34
-
-
0031412632
-
Functional epitope mapping of human interleukin 1β by surface plasmon resonance
-
D'Ettorre C., De Chiara G., Casadei R., Boraschi D., and Tagliabue A. Functional epitope mapping of human interleukin 1β by surface plasmon resonance. Eur. Cytokine Netw. 8 (1997) 161-171
-
(1997)
Eur. Cytokine Netw.
, vol.8
, pp. 161-171
-
-
D'Ettorre, C.1
De Chiara, G.2
Casadei, R.3
Boraschi, D.4
Tagliabue, A.5
-
35
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold S.S., Kaisho T., Hemmi H., Akira S., and Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303 (2004) 1529-1531
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis e Sousa, C.5
-
36
-
-
0031831906
-
Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist
-
Dinarello C.A. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int. Rev. Immunol. 16 (1998) 457-499
-
(1998)
Int. Rev. Immunol.
, vol.16
, pp. 457-499
-
-
Dinarello, C.A.1
-
37
-
-
20644450101
-
Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105
-
Divanovic S., Trompette A., Atabani S.F., Madan R., Golenbock D.T., Visintin A., Finberg R.W., Tarakhovsky A., Vogel S.N., Belkaid J., Kurt-Jones E.A., and Karp C.L. Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat. Immunol. 6 (2005) 571-578
-
(2005)
Nat. Immunol.
, vol.6
, pp. 571-578
-
-
Divanovic, S.1
Trompette, A.2
Atabani, S.F.3
Madan, R.4
Golenbock, D.T.5
Visintin, A.6
Finberg, R.W.7
Tarakhovsky, A.8
Vogel, S.N.9
Belkaid, J.10
Kurt-Jones, E.A.11
Karp, C.L.12
-
38
-
-
0034456693
-
Three novel mammalian toll-like receptors: Gene structure, expression, and evolution
-
Du X., Poltorak A., Wei Y., and Beutler B. Three novel mammalian toll-like receptors: Gene structure, expression, and evolution. Eur. Cytokine Netw. 11 (2000) 362-371
-
(2000)
Eur. Cytokine Netw.
, vol.11
, pp. 362-371
-
-
Du, X.1
Poltorak, A.2
Wei, Y.3
Beutler, B.4
-
39
-
-
0035472206
-
Annotating genes with potential roles in the immune system: Six new members of the IL-1 family
-
Dunn E., Sims J.E., Nicklin M.J., and O'Neill L.A. Annotating genes with potential roles in the immune system: Six new members of the IL-1 family. Trends Immunol. 22 (2001) 533-536
-
(2001)
Trends Immunol.
, vol.22
, pp. 533-536
-
-
Dunn, E.1
Sims, J.E.2
Nicklin, M.J.3
O'Neill, L.A.4
-
40
-
-
0037465251
-
The interleukin-1 receptor/Toll-like receptor superfamily: Signal transduction during inflammation and host defense
-
Dunne A., and O'Neill L.A. The interleukin-1 receptor/Toll-like receptor superfamily: Signal transduction during inflammation and host defense. Sci. STKE 2003 (2003) re3
-
(2003)
Sci. STKE
, vol.2003
-
-
Dunne, A.1
O'Neill, L.A.2
-
41
-
-
0025021471
-
Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist
-
Eisenberg S.P., Evans R.J., Arend W.P., Verderber E., Brewer M.T., Hannum C.H., and Thompson R.C. Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist. Nature 343 (1990) 341-346
-
(1990)
Nature
, vol.343
, pp. 341-346
-
-
Eisenberg, S.P.1
Evans, R.J.2
Arend, W.P.3
Verderber, E.4
Brewer, M.T.5
Hannum, C.H.6
Thompson, R.C.7
-
42
-
-
0034920683
-
Primitive Toll signaling: Bugs, flies, worms and man
-
Fallon P.G., Allen R.L., and Rich T. Primitive Toll signaling: Bugs, flies, worms and man. Trends Immunol. 22 (2001) 63-66
-
(2001)
Trends Immunol.
, vol.22
, pp. 63-66
-
-
Fallon, P.G.1
Allen, R.L.2
Rich, T.3
-
43
-
-
0037218354
-
Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity
-
Gao W., Kumar S., Lotze M.T., Hanning C., Robbins P.D., and Gambotto A. Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity. J. Immunol. 170 (2003) 107-113
-
(2003)
J. Immunol.
, vol.170
, pp. 107-113
-
-
Gao, W.1
Kumar, S.2
Lotze, M.T.3
Hanning, C.4
Robbins, P.D.5
Gambotto, A.6
-
44
-
-
12144287484
-
Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family
-
Garlanda C., Riva F., Polentarutti N., Buracchi C., Sironi M., De Bortoli M., Muzio M., Bergottini R., Scanziani E., Vecchi A., Hirsch E., and Mantovani A. Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. Proc. Natl. Acad. Sci. USA 101 (2004) 3522-3526
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3522-3526
-
-
Garlanda, C.1
Riva, F.2
Polentarutti, N.3
Buracchi, C.4
Sironi, M.5
De Bortoli, M.6
Muzio, M.7
Bergottini, R.8
Scanziani, E.9
Vecchi, A.10
Hirsch, E.11
Mantovani, A.12
-
45
-
-
0025774776
-
Drosophila Toll and IL-1 receptor
-
Gay N.J., and Keith F.J. Drosophila Toll and IL-1 receptor. Nature 351 (1991) 355-356
-
(1991)
Nature
, vol.351
, pp. 355-356
-
-
Gay, N.J.1
Keith, F.J.2
-
46
-
-
0029864182
-
Cloning of a putative ligand for the T1/ST2 receptor
-
Gayle M.A., Slack J.L., Bonnert T.P., Renshaw B.R., Sonoda G., Taguchi T., Testa J.R., Dower S.K., and Sims J.E. Cloning of a putative ligand for the T1/ST2 receptor. J. Biol. Chem. 271 (1996) 5784-5789
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5784-5789
-
-
Gayle, M.A.1
Slack, J.L.2
Bonnert, T.P.3
Renshaw, B.R.4
Sonoda, G.5
Taguchi, T.6
Testa, J.R.7
Dower, S.K.8
Sims, J.E.9
-
47
-
-
0037148510
-
Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for atherogenesis
-
Gerdes N., Sukhova G.K., Libby P., Reynolds R.S., Young J.L., and Schonbeck U. Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for atherogenesis. J. Exp. Med. 195 (2002) 245-257
-
(2002)
J. Exp. Med.
, vol.195
, pp. 245-257
-
-
Gerdes, N.1
Sukhova, G.K.2
Libby, P.3
Reynolds, R.S.4
Young, J.L.5
Schonbeck, U.6
-
48
-
-
0345303939
-
Lessons from Nod2 studies: Towards a link between Crohn's disease and bacterial sensing
-
Girardin S.E., Hugot J.P., and Sansonetti P.J. Lessons from Nod2 studies: Towards a link between Crohn's disease and bacterial sensing. Trends Immunol. 24 (2003) 652-658
-
(2003)
Trends Immunol.
, vol.24
, pp. 652-658
-
-
Girardin, S.E.1
Hugot, J.P.2
Sansonetti, P.J.3
-
49
-
-
0029009910
-
Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex
-
Greenfeder S.A., Nunes P., Kwee L., Labow M., Chizzonite R.A., and Ju G. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270 (1995) 13757-13765
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13757-13765
-
-
Greenfeder, S.A.1
Nunes, P.2
Kwee, L.3
Labow, M.4
Chizzonite, R.A.5
Ju, G.6
-
50
-
-
0026554371
-
The chicken IL-1 receptor: Differential evolution of the cytoplasmic and extracellular domains
-
Guida S., Heguy A., and Melli M. The chicken IL-1 receptor: Differential evolution of the cytoplasmic and extracellular domains. Gene 111 (1992) 239-243
-
(1992)
Gene
, vol.111
, pp. 239-243
-
-
Guida, S.1
Heguy, A.2
Melli, M.3
-
51
-
-
0347627721
-
Human dendritic cells express the IL-18R and are chemoattracted to IL-18
-
Gutzmer R., Langer K., Mommert S., Wittmann M., Kapp A., and Werfel T. Human dendritic cells express the IL-18R and are chemoattracted to IL-18. J. Immunol. 171 (2003) 6363-6371
-
(2003)
J. Immunol.
, vol.171
, pp. 6363-6371
-
-
Gutzmer, R.1
Langer, K.2
Mommert, S.3
Wittmann, M.4
Kapp, A.5
Werfel, T.6
-
52
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi F., Smith K.D., Ozinsky A., Hawn T.R., Yi E.C., Goodlett D.R., Eng J.K., Akira S., Underhill D.M., and Aderem A. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410 (2001) 1099-1103
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
Eng, J.K.7
Akira, S.8
Underhill, D.M.9
Aderem, A.10
-
53
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8
-
Heil F., Hemmi H., Hochrein H., Ampenberger F., Kirschning C., Akira S., Lipford G., Wagner H., and Bauer S. Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8. Science 303 (2004) 1526-1529
-
(2004)
Science
, vol.303
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
54
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H., Takeuchi O., Kawai T., Kaisho T., Sato S., Sanjo H., Matsumoto M., Hoshino K., Wagner H., Takeda K., and Akira S. A Toll-like receptor recognizes bacterial DNA. Nature 408 (2000) 740-745
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
56
-
-
0035474227
-
The NOD: A signaling module that regulates apoptosis and host defense against pathogens
-
Inohara N., and Nunez G. The NOD: A signaling module that regulates apoptosis and host defense against pathogens. Oncogene 20 (2001) 6473-6481
-
(2001)
Oncogene
, vol.20
, pp. 6473-6481
-
-
Inohara, N.1
Nunez, G.2
-
57
-
-
0034657781
-
IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-1 receptor accessory protein
-
Jensen L.E., Muzio M., Mantovani A., and Whitehead A.S. IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-1 receptor accessory protein. J. Immunol. 164 (2000) 5277-5286
-
(2000)
J. Immunol.
, vol.164
, pp. 5277-5286
-
-
Jensen, L.E.1
Muzio, M.2
Mantovani, A.3
Whitehead, A.S.4
-
58
-
-
0034102258
-
Two novel members of the interleukin-1 receptor gene family, one deleted in Xp22. 1-Xp21. 3 mental retardation
-
Jin H., Gardner R.J., Viswesvaraiah R., Muntoni F., and Roberts R.G. Two novel members of the interleukin-1 receptor gene family, one deleted in Xp22. 1-Xp21. 3 mental retardation. Eur. J. Hum. Genet. 8 (2000) 87-94
-
(2000)
Eur. J. Hum. Genet.
, vol.8
, pp. 87-94
-
-
Jin, H.1
Gardner, R.J.2
Viswesvaraiah, R.3
Muntoni, F.4
Roberts, R.G.5
-
59
-
-
0037213692
-
Evolutionary clues to the functions of the Toll-like family as surveillance receptors
-
Johnson G.B., Brunn G.J., Tang A.H., and Platt J.L. Evolutionary clues to the functions of the Toll-like family as surveillance receptors. Trends Immunol. 24 (2003) 19-24
-
(2003)
Trends Immunol.
, vol.24
, pp. 19-24
-
-
Johnson, G.B.1
Brunn, G.J.2
Tang, A.H.3
Platt, J.L.4
-
60
-
-
0035080102
-
Levels of interleukin-18 and its binding inhibitors in the blood circulation of patients with adult-onset Still's disease
-
Kawashima M., Yamamura M., Taniai M., Yamauchi H., Tanimoto T., Kurimoto M., Miyawaki S., Amano T., Takeuchi T., and Makino H. Levels of interleukin-18 and its binding inhibitors in the blood circulation of patients with adult-onset Still's disease. Arthritis Rheum. 44 (2001) 550-560
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 550-560
-
-
Kawashima, M.1
Yamamura, M.2
Taniai, M.3
Yamauchi, H.4
Tanimoto, T.5
Kurimoto, M.6
Miyawaki, S.7
Amano, T.8
Takeuchi, T.9
Makino, H.10
-
61
-
-
0036899791
-
RP105-lacking B cells from lupus patients are responsible for the production of immunoglobulins and autoantibodies
-
Kikuchi Y., Koarada S., Tada Y., Ushiyama O., Morito F., Suzuki N., Ohta A., Miyake K., Kimoto M., Horiuchi T., and Nagasawa K. RP105-lacking B cells from lupus patients are responsible for the production of immunoglobulins and autoantibodies. Arthritis Rheum. 46 (2002) 3259-3265
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 3259-3265
-
-
Kikuchi, Y.1
Koarada, S.2
Tada, Y.3
Ushiyama, O.4
Morito, F.5
Suzuki, N.6
Ohta, A.7
Miyake, K.8
Kimoto, M.9
Horiuchi, T.10
Nagasawa, K.11
-
62
-
-
0035321067
-
The evolution and genetics of innate immunity
-
Kimbrell D.A., and Beutler B. The evolution and genetics of innate immunity. Nat. Rev. Genet. 2 (2001) 256-267
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 256-267
-
-
Kimbrell, D.A.1
Beutler, B.2
-
63
-
-
0033974776
-
Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18
-
Kim S.H., Eisenstein M., Reznikov L., Fantuzzi G., Novick D., Rubinstein M., and Dinarello C.A. Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18. Proc. Natl. Acad. Sci. USA 97 (2000) 1190-1195
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1190-1195
-
-
Kim, S.H.1
Eisenstein, M.2
Reznikov, L.3
Fantuzzi, G.4
Novick, D.5
Rubinstein, M.6
Dinarello, C.A.7
-
64
-
-
0035168657
-
Functional reconstitution and regulation of IL-18 activity by the IL-18Rβ chain
-
Kim S.H., Reznikov L.L., Stuyt R.J., Selzman C.H., Fantuzzi G., Hoshino T., Young H.A., and Dinarello C.A. Functional reconstitution and regulation of IL-18 activity by the IL-18Rβ chain. J. Immunol. 166 (2001) 148-154
-
(2001)
J. Immunol.
, vol.166
, pp. 148-154
-
-
Kim, S.H.1
Reznikov, L.L.2
Stuyt, R.J.3
Selzman, C.H.4
Fantuzzi, G.5
Hoshino, T.6
Young, H.A.7
Dinarello, C.A.8
-
65
-
-
0037192869
-
Identification of amino acid residues critical for biological activity in human interleukin-18
-
Kim S.H., Azam T., Novick D., Yoon D.Y., Reznikov L.L., Bufler P., Rubinstein M., and Dinarello C.A. Identification of amino acid residues critical for biological activity in human interleukin-18. J. Biol. Chem. 277 (2002) 10998-11003
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10998-11003
-
-
Kim, S.H.1
Azam, T.2
Novick, D.3
Yoon, D.Y.4
Reznikov, L.L.5
Bufler, P.6
Rubinstein, M.7
Dinarello, C.A.8
-
66
-
-
0035182535
-
CD180 (RP105) in rheumatic diseases
-
Koarada S., Tada Y., Kikuchi Y., Ushiyama O., Suzuki N., Ohta A., and Nagasawa K. CD180 (RP105) in rheumatic diseases. Rheumatology 40 (2001) 1315-1316
-
(2001)
Rheumatology
, vol.40
, pp. 1315-1316
-
-
Koarada, S.1
Tada, Y.2
Kikuchi, Y.3
Ushiyama, O.4
Suzuki, N.5
Ohta, A.6
Nagasawa, K.7
-
67
-
-
0034731378
-
The first two N-terminal immunoglobulin-like domains of soluble human IL-1 receptor type II are sufficient to bind and neutralize IL-1β
-
Kollewe C., Neumann D., and Martin M.U. The first two N-terminal immunoglobulin-like domains of soluble human IL-1 receptor type II are sufficient to bind and neutralize IL-1β. FEBS Lett. 29 (2000) 189-193
-
(2000)
FEBS Lett.
, vol.29
, pp. 189-193
-
-
Kollewe, C.1
Neumann, D.2
Martin, M.U.3
-
68
-
-
0031013038
-
A critical role for interleukin-1 receptor accessory protein in interleukin-1 signaling
-
Korherr C., Hofmeister R., Wesche H., and Falk W. A critical role for interleukin-1 receptor accessory protein in interleukin-1 signaling. Eur. J. Immunol. 27 (1997) 262-267
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 262-267
-
-
Korherr, C.1
Hofmeister, R.2
Wesche, H.3
Falk, W.4
-
69
-
-
0036020218
-
Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-γ production
-
Kumar S., Hanning C.R., Brigham-Burke M.R., Rieman D.J., Lehr R., Khandekar S., Kirkpatrick R.B., Scott G.F., Lee J.C., Lynch F.J., Gao W., Gambotto A., et al. Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-γ production. Cytokine 18 (2002) 61-71
-
(2002)
Cytokine
, vol.18
, pp. 61-71
-
-
Kumar, S.1
Hanning, C.R.2
Brigham-Burke, M.R.3
Rieman, D.J.4
Lehr, R.5
Khandekar, S.6
Kirkpatrick, R.B.7
Scott, G.F.8
Lee, J.C.9
Lynch, F.J.10
Gao, W.11
Gambotto, A.12
-
70
-
-
0034816240
-
Identification of human ST2 protein in the sera of patients with autoimmune diseases
-
Kuroiwa K., Arai T., Okazaki H., Minota S., and Tominaga S. Identification of human ST2 protein in the sera of patients with autoimmune diseases. Biochem. Biophys. Res. Commun. 284 (2001) 1104-1108
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.284
, pp. 1104-1108
-
-
Kuroiwa, K.1
Arai, T.2
Okazaki, H.3
Minota, S.4
Tominaga, S.5
-
71
-
-
0032534729
-
The type II interleukin-1 receptor interacts with the interleukin-1 receptor accessory protein: A novel mechanism of regulation of the interleukin-1 responsiveness
-
Lang D., Knop J., Wesche H., Raffetseder U., Kurrle R., Boraschi D., and Martin M.U. The type II interleukin-1 receptor interacts with the interleukin-1 receptor accessory protein: A novel mechanism of regulation of the interleukin-1 responsiveness. J. Immunol. 161 (1998) 6871-6877
-
(1998)
J. Immunol.
, vol.161
, pp. 6871-6877
-
-
Lang, D.1
Knop, J.2
Wesche, H.3
Raffetseder, U.4
Kurrle, R.5
Boraschi, D.6
Martin, M.U.7
-
72
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B., Nicolas E., Michaut L., Reichhart J.M., and Hoffmann J.A. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86 (1996) 973-983
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
73
-
-
2942702125
-
A novel therapy of murine collagen-induced arthritis with soluble T1/ST2
-
Leung B.P., Xy D., Culshaw S., McInnes I.B., and Liew F.Y. A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. J. Immunol. 173 (2004) 145-150
-
(2004)
J. Immunol.
, vol.173
, pp. 145-150
-
-
Leung, B.P.1
Xy, D.2
Culshaw, S.3
McInnes, I.B.4
Liew, F.Y.5
-
74
-
-
0034253797
-
The cloning and nucleotide sequence of human ST2L cDNA
-
Li H., Tago K., Io K., Kuroiwa K., Arai T., Iwahana H., Tominaga S., and Yanagisawa K. The cloning and nucleotide sequence of human ST2L cDNA. Genomics 67 (2000) 284-290
-
(2000)
Genomics
, vol.67
, pp. 284-290
-
-
Li, H.1
Tago, K.2
Io, K.3
Kuroiwa, K.4
Arai, T.5
Iwahana, H.6
Tominaga, S.7
Yanagisawa, K.8
-
75
-
-
18744388579
-
Modulation of Toll-interleukin 1 receptor mediated signaling
-
Li X., and Qin J. Modulation of Toll-interleukin 1 receptor mediated signaling. J. Mol. Med. 83 (2005) 258-266
-
(2005)
J. Mol. Med.
, vol.83
, pp. 258-266
-
-
Li, X.1
Qin, J.2
-
76
-
-
20644450804
-
Negative regulation of Toll-like receptor-mediated immune responses
-
Liew F.Y., Xu D., Brint E.K., and O'Neill L.A.J. Negative regulation of Toll-like receptor-mediated immune responses. Nat. Rev. Immunol. 5 (2005) 446-458
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 446-458
-
-
Liew, F.Y.1
Xu, D.2
Brint, E.K.3
O'Neill, L.A.J.4
-
77
-
-
0032499678
-
T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function
-
Lohning M., Stroehmann A., Coyle A.J., Grogan J.L., Lin S., Gutierrez-Ramos J.C., Levinson D., Radbruch A., and Kamradt T. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc. Natl. Acad. Sci. USA 95 (1998) 6930-6935
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6930-6935
-
-
Lohning, M.1
Stroehmann, A.2
Coyle, A.J.3
Grogan, J.L.4
Lin, S.5
Gutierrez-Ramos, J.C.6
Levinson, D.7
Radbruch, A.8
Kamradt, T.9
-
78
-
-
1842631428
-
Recognition of single-stranded RNA viruses by Toll-like receptor 7
-
Lund J., Alexopoulou M.L., Sato A., Karow M., Adams N.C., Gale N.W., Iwasaki A., and Flavell R.A. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc. Natl. Acad. Sci. USA 101 (2004) 5598-5603
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5598-5603
-
-
Lund, J.1
Alexopoulou, M.L.2
Sato, A.3
Karow, M.4
Adams, N.C.5
Gale, N.W.6
Iwasaki, A.7
Flavell, R.A.8
-
79
-
-
0034098633
-
Independent evolution of Toll and related genes in insects and mammals
-
Luo C., and Zheng L. Independent evolution of Toll and related genes in insects and mammals. Immunogenetics 51 (2000) 92-98
-
(2000)
Immunogenetics
, vol.51
, pp. 92-98
-
-
Luo, C.1
Zheng, L.2
-
80
-
-
0032537506
-
Interleukin-1 receptor accessory protein interacts with the type II interleukin-1 receptor
-
Malinowsky D., Lundkvist J., Laye S., and Bartfai T. Interleukin-1 receptor accessory protein interacts with the type II interleukin-1 receptor. FEBS Lett. 429 (1998) 299-302
-
(1998)
FEBS Lett.
, vol.429
, pp. 299-302
-
-
Malinowsky, D.1
Lundkvist, J.2
Laye, S.3
Bartfai, T.4
-
81
-
-
2542457495
-
Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
-
Martinon F., and Tschopp J. Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases. Cell 117 (2004) 561-574
-
(2004)
Cell
, vol.117
, pp. 561-574
-
-
Martinon, F.1
Tschopp, J.2
-
82
-
-
0025899561
-
A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types
-
McMahan C.J., Slack J.L., Mosley B., Cosman D., Lupton S.D., Brunton L.L., Grubin C.E., Wignall J.M., Jenkins N.A., Brannan C.I., Copeland N.G., Huebner K., et al. A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. EMBO J. 10 (1991) 2821-2832
-
(1991)
EMBO J.
, vol.10
, pp. 2821-2832
-
-
McMahan, C.J.1
Slack, J.L.2
Mosley, B.3
Cosman, D.4
Lupton, S.D.5
Brunton, L.L.6
Grubin, C.E.7
Wignall, J.M.8
Jenkins, N.A.9
Brannan, C.I.10
Copeland, N.G.11
Huebner, K.12
-
83
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R., Preston-Hurlburt P., and Janeway Jr. C.A. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388 (1997) 394-397
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
84
-
-
0029863950
-
T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family
-
Mitcham J.L., Parnet P., Bonnert T.P., Garka K.E., Gerhart M.J., Slack J.L., Gayle M.A., Dower S.K., and Sims J.E. T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family. J. Biol. Chem. 271 (1996) 5777-5783
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5777-5783
-
-
Mitcham, J.L.1
Parnet, P.2
Bonnert, T.P.3
Garka, K.E.4
Gerhart, M.J.5
Slack, J.L.6
Gayle, M.A.7
Dower, S.K.8
Sims, J.E.9
-
85
-
-
0032532315
-
RP105 is associated with MD-1 and transmits an activation signal in human B cells
-
Miura Y., Shimazu R., Miyake K., Akashi S., Ogata H., Yamashita Y., Narisawa Y., and Kimoto M. RP105 is associated with MD-1 and transmits an activation signal in human B cells. Blood 92 (1998) 2815-2822
-
(1998)
Blood
, vol.92
, pp. 2815-2822
-
-
Miura, Y.1
Shimazu, R.2
Miyake, K.3
Akashi, S.4
Ogata, H.5
Yamashita, Y.6
Narisawa, Y.7
Kimoto, M.8
-
86
-
-
0028949390
-
RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family
-
Miyake K., Yamashita Y., Ogata M., Sudo T., and Kimoto M. RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. J. Immunol. 154 (1995) 3333-3340
-
(1995)
J. Immunol.
, vol.154
, pp. 3333-3340
-
-
Miyake, K.1
Yamashita, Y.2
Ogata, M.3
Sudo, T.4
Kimoto, M.5
-
87
-
-
0035059650
-
Expression of interleukin-18 and its monokine-directed function in rheumatoid arthritis
-
Moller B., Kukoc-Zivojnov N., Kessler U., Rehart S., Kaltwasser J.P., Hoelzer D., Kalina U., and Ottmann O.G. Expression of interleukin-18 and its monokine-directed function in rheumatoid arthritis. Rheumatology (Oxford) 40 (2001) 302-309
-
(2001)
Rheumatology (Oxford)
, vol.40
, pp. 302-309
-
-
Moller, B.1
Kukoc-Zivojnov, N.2
Kessler, U.3
Rehart, S.4
Kaltwasser, J.P.5
Hoelzer, D.6
Kalina, U.7
Ottmann, O.G.8
-
88
-
-
0035956425
-
Evolutionary perspective on innate immune recognition
-
Mushegian A., and Medzhitov R. Evolutionary perspective on innate immune recognition. J. Cell Biol. 155 (2001) 705-710
-
(2001)
J. Cell Biol.
, vol.155
, pp. 705-710
-
-
Mushegian, A.1
Medzhitov, R.2
-
89
-
-
0034817193
-
Interleukin-12 upregulates the IL-18Rβ chain in BALB/c thymocytes
-
Neumann D., and Martin M.U. Interleukin-12 upregulates the IL-18Rβ chain in BALB/c thymocytes. J. Interferon Cytokine Res. 21 (2001) 635-642
-
(2001)
J. Interferon Cytokine Res.
, vol.21
, pp. 635-642
-
-
Neumann, D.1
Martin, M.U.2
-
90
-
-
0034665374
-
The membrane form of the type II IL-1 receptor accounts for inhibitory function
-
Neumann D., Kollewe C., Martin M.U., and Boraschi D. The membrane form of the type II IL-1 receptor accounts for inhibitory function. J. Immunol. 165 (2000) 3350-3357
-
(2000)
J. Immunol.
, vol.165
, pp. 3350-3357
-
-
Neumann, D.1
Kollewe, C.2
Martin, M.U.3
Boraschi, D.4
-
91
-
-
0028085306
-
A physical map of the region encompassing the human interleukin-1α, interleukin-1β, and interleukin-1 receptor antagonist genes
-
Nicklin M.J., Weith A., and Duff G.W. A physical map of the region encompassing the human interleukin-1α, interleukin-1β, and interleukin-1 receptor antagonist genes. Genomics 19 (1994) 382-384
-
(1994)
Genomics
, vol.19
, pp. 382-384
-
-
Nicklin, M.J.1
Weith, A.2
Duff, G.W.3
-
92
-
-
0032983336
-
Interleukin-18 binding protein: A novel modulator of the Th1 cytokine response
-
Novick D., Kim S.H., Fantuzzi G., Reznikov L.L., Dinarello C.A., and Rubinstein M. Interleukin-18 binding protein: A novel modulator of the Th1 cytokine response. Immunity 10 (1999) 127-136
-
(1999)
Immunity
, vol.10
, pp. 127-136
-
-
Novick, D.1
Kim, S.H.2
Fantuzzi, G.3
Reznikov, L.L.4
Dinarello, C.A.5
Rubinstein, M.6
-
93
-
-
0034601022
-
The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells
-
Ogata H., Su I., Miyake K., Nagai Y., Akashi S., Mecklenbrauker I., Rajewsky K., Kimoto M., and Tarakhovsky A. The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells. J. Exp. Med. 192 (2000) 23-29
-
(2000)
J. Exp. Med.
, vol.192
, pp. 23-29
-
-
Ogata, H.1
Su, I.2
Miyake, K.3
Nagai, Y.4
Akashi, S.5
Mecklenbrauker, I.6
Rajewsky, K.7
Kimoto, M.8
Tarakhovsky, A.9
-
94
-
-
0028845730
-
Cloning of a new cytokine that induces IFN-γ production by T cells
-
Okamura H., Tsutsui H., Komatsu T., Yutsudo M., Hakura A., Tanimoto T., Torigoe K., Okura T., Nukada Y., Hattori K., Akita K., Namba M., et al. Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 378 (1995) 88-91
-
(1995)
Nature
, vol.378
, pp. 88-91
-
-
Okamura, H.1
Tsutsui, H.2
Komatsu, T.3
Yutsudo, M.4
Hakura, A.5
Tanimoto, T.6
Torigoe, K.7
Okura, T.8
Nukada, Y.9
Hattori, K.10
Akita, K.11
Namba, M.12
-
95
-
-
0034304668
-
The Toll/interleukin-1 receptor domain: A molecular switch for inflammation and host defence
-
O'Neill L.A. The Toll/interleukin-1 receptor domain: A molecular switch for inflammation and host defence. Biochem. Soc. Trans. 28 (2000) 557-563
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 557-563
-
-
O'Neill, L.A.1
-
96
-
-
0031801957
-
Signal transduction pathways activated by the IL-1 receptor family: Ancient signaling machinery in mammals, insects, and plants
-
O'Neill L.A., and Greene C. Signal transduction pathways activated by the IL-1 receptor family: Ancient signaling machinery in mammals, insects, and plants. J. Leukoc. Biol. 63 (1998) 650-657
-
(1998)
J. Leukoc. Biol.
, vol.63
, pp. 650-657
-
-
O'Neill, L.A.1
Greene, C.2
-
97
-
-
0031454425
-
Role of metalloproteases in the release of the IL-1 type II decoy receptor
-
Orlando S., Sironi M., Bianchi G., Drummond A.H., Boraschi D., Yabes D., and Mantovani A. Role of metalloproteases in the release of the IL-1 type II decoy receptor. J. Biol. Chem. 272 (1997) 31764-31769
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 31764-31769
-
-
Orlando, S.1
Sironi, M.2
Bianchi, G.3
Drummond, A.H.4
Boraschi, D.5
Yabes, D.6
Mantovani, A.7
-
99
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
-
Ozinsky A., Underhill D.M., Fontenot J.D., Hajjar A.M., Smith K.D., Wilson C.B., Schroeder L., and Aderem A. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc. Natl. Acad. Sci. USA 97 (2000) 13766-13771
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
Hajjar, A.M.4
Smith, K.D.5
Wilson, C.B.6
Schroeder, L.7
Aderem, A.8
-
100
-
-
0029989325
-
IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP
-
Parnet P., Garka K.E., Bonnert T.P., Dower S.K., and Sims J.E. IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP. J. Biol. Chem. 271 (1996) 3967-3970
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3967-3970
-
-
Parnet, P.1
Garka, K.E.2
Bonnert, T.P.3
Dower, S.K.4
Sims, J.E.5
-
101
-
-
0035892991
-
Expression and release of IL-18 binding protein in response to IFN-γ
-
Paulukat J., Bosmann M., Nold M., Garkisch S., Kampfer H., Frank S., Raedle J., Zeuzem S., Pfeilschifter J., and Muhl H. Expression and release of IL-18 binding protein in response to IFN-γ. J. Immunol. 167 (2001) 7038-7043
-
(2001)
J. Immunol.
, vol.167
, pp. 7038-7043
-
-
Paulukat, J.1
Bosmann, M.2
Nold, M.3
Garkisch, S.4
Kampfer, H.5
Frank, S.6
Raedle, J.7
Zeuzem, S.8
Pfeilschifter, J.9
Muhl, H.10
-
102
-
-
1642498347
-
Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR
-
Polentarutti N., Penton Rol G., Muzio M., Bosisio D., Camnasio M., Riva F., Zoja C., Benigni A., Tomasoni S., Vecchi A., Garlanda C., and Mantovani A. Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR. Eur. Cytokine Netw. 14 (2003) 211-218
-
(2003)
Eur. Cytokine Netw.
, vol.14
, pp. 211-218
-
-
Polentarutti, N.1
Penton Rol, G.2
Muzio, M.3
Bosisio, D.4
Camnasio, M.5
Riva, F.6
Zoja, C.7
Benigni, A.8
Tomasoni, S.9
Vecchi, A.10
Garlanda, C.11
Mantovani, A.12
-
103
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A., He X., Smirnova I., Liu M.Y., Huffel C.V., Du X., Birdwell C., Alejos E., Silva M., Galanos C., Freudenberg M., Ricciardi-Castagnoli P., et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 282 (1998) 2085-2088
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Huffel, C.V.5
Du, X.6
Birdwell, C.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
Ricciardi-Castagnoli, P.12
-
104
-
-
0034745671
-
Clinical relevance of T1-S, an oncogene-inducible, secreted glycoprotein of the immunoglobulin superfamily, in node-negative breast cancer
-
Prechtel D., Harbeck N., Berger U., Hofler H., and Werenskiold A.K. Clinical relevance of T1-S, an oncogene-inducible, secreted glycoprotein of the immunoglobulin superfamily, in node-negative breast cancer. Lab. Invest. 81 (2001) 159-165
-
(2001)
Lab. Invest.
, vol.81
, pp. 159-165
-
-
Prechtel, D.1
Harbeck, N.2
Berger, U.3
Hofler, H.4
Werenskiold, A.K.5
-
105
-
-
0035811018
-
A reverse genetic analysis of components of the Toll signaling pathway in Caenorhabditis elegans
-
Pujol N., Link E.M., Liu L.X., Kurz C.L., Alloing G., Tan M.-W., Ray K.P., Solari R., Johnson C.D., and Ewbank J.J. A reverse genetic analysis of components of the Toll signaling pathway in Caenorhabditis elegans. Curr. Biol. 11 (2001) 809-821
-
(2001)
Curr. Biol.
, vol.11
, pp. 809-821
-
-
Pujol, N.1
Link, E.M.2
Liu, L.X.3
Kurz, C.L.4
Alloing, G.5
Tan, M.-W.6
Ray, K.P.7
Solari, R.8
Johnson, C.D.9
Ewbank, J.J.10
-
106
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum S., Paglino J., Eslami-Varzaneh F., Edberg S., and Medzhitov S. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118 (2004) 229-241
-
(2004)
Cell
, vol.118
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, S.5
-
107
-
-
0029924136
-
Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: A surface 'receptor' with anti-interleukin-1 function
-
Re F., Sironi M., Muzio M., Matteucci C., Introna M., Orlando S., Penton-Rol G., Dower S.K., Sims J.E., Colotta F., and Mantovani A. Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: A surface 'receptor' with anti-interleukin-1 function. J. Exp. Med. 183 (1996) 1841-1850
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1841-1850
-
-
Re, F.1
Sironi, M.2
Muzio, M.3
Matteucci, C.4
Introna, M.5
Orlando, S.6
Penton-Rol, G.7
Dower, S.K.8
Sims, J.E.9
Colotta, F.10
Mantovani, A.11
-
108
-
-
0031905311
-
A family of human receptors structurally related to Drosophila Toll
-
Rock L., Hardiman G., Timans J.C., Kastelein R.A., and Bazan J.F. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. USA 95 (1998) 588-593
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 588-593
-
-
Rock, L.1
Hardiman, G.2
Timans, J.C.3
Kastelein, R.A.4
Bazan, J.F.5
-
109
-
-
0034667308
-
Computational identification, cloning, and characterization of IL-1R9, a novel interleukin-1 receptor-like gene encoded over an unusually large interval of human chromosome Xq22. 2-q22. 3
-
Sana T.R., Debets R., Timans J.C., Bazan J.F., and Kastelein R.A. Computational identification, cloning, and characterization of IL-1R9, a novel interleukin-1 receptor-like gene encoded over an unusually large interval of human chromosome Xq22. 2-q22. 3. Genomics 69 (2000) 252-262
-
(2000)
Genomics
, vol.69
, pp. 252-262
-
-
Sana, T.R.1
Debets, R.2
Timans, J.C.3
Bazan, J.F.4
Kastelein, R.A.5
-
110
-
-
0034536209
-
Cloning and characterization of the rainbow trout (Oncorhynchus mykiss) type II interleukin-1 receptor cDNA
-
Sangrador-Vegas A., Martin S.A., O'Dea P.G., and Smith T.J. Cloning and characterization of the rainbow trout (Oncorhynchus mykiss) type II interleukin-1 receptor cDNA. Eur. J. Biochem. 267 (2000) 7031-7037
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 7031-7037
-
-
Sangrador-Vegas, A.1
Martin, S.A.2
O'Dea, P.G.3
Smith, T.J.4
-
111
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J., Owyang A., Oldham E., Song Y., Murphy E., McClanahan T.K., Zurawski G., Moshrefi M., Qin J., Li X., Gorman D.M., Bazan J.F., et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23 (2005) 479-490
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
Song, Y.4
Murphy, E.5
McClanahan, T.K.6
Zurawski, G.7
Moshrefi, M.8
Qin, J.9
Li, X.10
Gorman, D.M.11
Bazan, J.F.12
-
112
-
-
0031000052
-
A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist
-
Schreuder H., Tardif C., Trump-Kallmeyer S., Soffientini A., Sarubbi E., Akeson A., Bowlin T., Yanofsky S., and Barrett R.W. A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist. Nature 386 (1997) 194-200
-
(1997)
Nature
, vol.386
, pp. 194-200
-
-
Schreuder, H.1
Tardif, C.2
Trump-Kallmeyer, S.3
Soffientini, A.4
Sarubbi, E.5
Akeson, A.6
Bowlin, T.7
Yanofsky, S.8
Barrett, R.W.9
-
113
-
-
0023683844
-
cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily
-
Sims J.E., March C.J., Cosman D., Widmer M.B., MacDonald H.R., McMahan C.J., Grubin C.E., Wignall J.M., Jackson J.L., Call S.M., Friend D., Alpert A.R., et al. cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. Science 241 (1988) 585-589
-
(1988)
Science
, vol.241
, pp. 585-589
-
-
Sims, J.E.1
March, C.J.2
Cosman, D.3
Widmer, M.B.4
MacDonald, H.R.5
McMahan, C.J.6
Grubin, C.E.7
Wignall, J.M.8
Jackson, J.L.9
Call, S.M.10
Friend, D.11
Alpert, A.R.12
-
114
-
-
0033958252
-
Four new members expand the interleukin-1 superfamily
-
Smith D.E., Renshaw B.R., Ketchem R.R., Kubin M., Garka K.E., and Sims J.E. Four new members expand the interleukin-1 superfamily. J. Biol. Chem. 275 (2000) 1169-1175
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1169-1175
-
-
Smith, D.E.1
Renshaw, B.R.2
Ketchem, R.R.3
Kubin, M.4
Garka, K.E.5
Sims, J.E.6
-
115
-
-
0037237908
-
The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action
-
Smith D.E., Hanna R., Friend D., Moore H., Chen H., Farese A.M., MacVittie T.J., Virca G.D., and Sims J.E. The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action. Immunity 18 (2003) 87-96
-
(2003)
Immunity
, vol.18
, pp. 87-96
-
-
Smith, D.E.1
Hanna, R.2
Friend, D.3
Moore, H.4
Chen, H.5
Farese, A.M.6
MacVittie, T.J.7
Virca, G.D.8
Sims, J.E.9
-
116
-
-
0036784616
-
IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response
-
Strengell M., Sareneva T., Foster D., Julkunen I., and Matikainen S. IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response. J. Immunol. 169 (2002) 3600-3605
-
(2002)
J. Immunol.
, vol.169
, pp. 3600-3605
-
-
Strengell, M.1
Sareneva, T.2
Foster, D.3
Julkunen, I.4
Matikainen, S.5
-
117
-
-
0036195371
-
Cloning of a Salmo salar interleukin-1 receptor-like cDNA
-
Subramaniam S., Stansberg C., Olsen L., Zou J., Secombes C.J., and Cunningham C. Cloning of a Salmo salar interleukin-1 receptor-like cDNA. Dev. Comp. Immunol. 26 (2002) 415-431
-
(2002)
Dev. Comp. Immunol.
, vol.26
, pp. 415-431
-
-
Subramaniam, S.1
Stansberg, C.2
Olsen, L.3
Zou, J.4
Secombes, C.J.5
Cunningham, C.6
-
118
-
-
0035336425
-
A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of Toll-like receptor 4 expression
-
Sweet M.J., Leung B.P., Kang D., Sogaard M., Schulz K., Trajkovic V., Campbell C.C., Xu D., and Liew F.Y. A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of Toll-like receptor 4 expression. J. Immunol. 166 (2001) 6633-6639
-
(2001)
J. Immunol.
, vol.166
, pp. 6633-6639
-
-
Sweet, M.J.1
Leung, B.P.2
Kang, D.3
Sogaard, M.4
Schulz, K.5
Trajkovic, V.6
Campbell, C.C.7
Xu, D.8
Liew, F.Y.9
-
119
-
-
0034807091
-
Tissue distribution and subcellular localization of a variant form of the human ST2 gene product, ST2V
-
Tago K., Noda T., Hayakawa M., Iwahana H., Yanagisawa K., Yashiro T., and Tominaga S. Tissue distribution and subcellular localization of a variant form of the human ST2 gene product, ST2V. Biochem. Biophys. Res. Commun. 285 (2001) 1377-1383
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.285
, pp. 1377-1383
-
-
Tago, K.1
Noda, T.2
Hayakawa, M.3
Iwahana, H.4
Yanagisawa, K.5
Yashiro, T.6
Tominaga, S.7
-
120
-
-
0142010561
-
The increase in serum soluble ST2 protein upon acute exacerbation of idiopathic pulmonary fibrosis
-
Tajima S., Oshikawa K., Tominaga S., and Sugiyama Y. The increase in serum soluble ST2 protein upon acute exacerbation of idiopathic pulmonary fibrosis. Chest 124 (2003) 1206-1214
-
(2003)
Chest
, vol.124
, pp. 1206-1214
-
-
Tajima, S.1
Oshikawa, K.2
Tominaga, S.3
Sugiyama, Y.4
-
121
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
-
Takeuchi O., Hoshino K., Kawai T., Sanjo H., Takada H., Ogawa T., Takeda K., and Akira S. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11 (1999) 443-451
-
(1999)
Immunity
, vol.11
, pp. 443-451
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
122
-
-
0033614428
-
TLR6: A novel member of an expanding toll-like receptor family
-
Takeuchi O., Kawai T., Sanjo H., Copeland N.G., Gilbert D.J., Jenkins N.A., Takeda K., and Akira S. TLR6: A novel member of an expanding toll-like receptor family. Gene 231 (1999) 59-65
-
(1999)
Gene
, vol.231
, pp. 59-65
-
-
Takeuchi, O.1
Kawai, T.2
Sanjo, H.3
Copeland, N.G.4
Gilbert, D.J.5
Jenkins, N.A.6
Takeda, K.7
Akira, S.8
-
123
-
-
0034650420
-
Cutting edge: Preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway
-
Takeuchi O., Kaufmann A., Grote K., Kawai K., Hoshino K., Morr M., Muhlradt P.F., and Akira S. Cutting edge: Preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway. J. Immunol. 164 (2000) 554-557
-
(2000)
J. Immunol.
, vol.164
, pp. 554-557
-
-
Takeuchi, O.1
Kaufmann, A.2
Grote, K.3
Kawai, K.4
Hoshino, K.5
Morr, M.6
Muhlradt, P.F.7
Akira, S.8
-
124
-
-
0036257305
-
Genomic organization of the interleukin-1 locus
-
Taylor S.L., Renshaw B.R., Garka K.E., Smith D.E., and Sims J.E. Genomic organization of the interleukin-1 locus. Genomics 79 (2002) 726-733
-
(2002)
Genomics
, vol.79
, pp. 726-733
-
-
Taylor, S.L.1
Renshaw, B.R.2
Garka, K.E.3
Smith, D.E.4
Sims, J.E.5
-
125
-
-
0033151633
-
Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily
-
Thomassen E., Renshaw B.R., and Sims J.E. Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily. Cytokine 11 (1999) 389-399
-
(1999)
Cytokine
, vol.11
, pp. 389-399
-
-
Thomassen, E.1
Renshaw, B.R.2
Sims, J.E.3
-
126
-
-
0030851728
-
Purification and characterization of the human interleukin-18 receptor
-
Torigoe K., Ushio S., Okura T., Kobayashi S., Taniai M., Kunikata T., Murakami T., Sanou O., Kojima H., Fujii M., Ohta T., Ikeda M., et al. Purification and characterization of the human interleukin-18 receptor. J. Biol. Chem. 272 (1997) 25737-25742
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25737-25742
-
-
Torigoe, K.1
Ushio, S.2
Okura, T.3
Kobayashi, S.4
Taniai, M.5
Kunikata, T.6
Murakami, T.7
Sanou, O.8
Kojima, H.9
Fujii, M.10
Ohta, T.11
Ikeda, M.12
-
127
-
-
1842640230
-
Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-κB and MAPKs
-
Towne J.E., Garka K.E., Renshaw B.R., Virca G.D., and Sims J.E. Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-κB and MAPKs. J. Biol. Chem. 279 (2004) 13677-13688
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 13677-13688
-
-
Towne, J.E.1
Garka, K.E.2
Renshaw, B.R.3
Virca, G.D.4
Sims, J.E.5
-
128
-
-
0034689033
-
T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses
-
Townsend M.J., Fallon P.G., Matthews D.J., Jolin H.E., and McKenzie A.N. T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses. J. Exp. Med. 191 (2000) 1069-1076
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1069-1076
-
-
Townsend, M.J.1
Fallon, P.G.2
Matthews, D.J.3
Jolin, H.E.4
McKenzie, A.N.5
-
129
-
-
1942535018
-
T1/ST2-an IL-1 receptor-like modulator of immune responses
-
Trajkovic V., Sweet M.J., and Xu D. T1/ST2-an IL-1 receptor-like modulator of immune responses. Cytokine Growth Factor Rev. 15 (2004) 87-95
-
(2004)
Cytokine Growth Factor Rev.
, vol.15
, pp. 87-95
-
-
Trajkovic, V.1
Sweet, M.J.2
Xu, D.3
-
131
-
-
0033592748
-
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
-
Underhill D.M., Ozinsky A., Hajjar A.M., Stevens A., Wilson C.B., Bassetti M., and Aderem A. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 401 (1999) 811-815
-
(1999)
Nature
, vol.401
, pp. 811-815
-
-
Underhill, D.M.1
Ozinsky, A.2
Hajjar, A.M.3
Stevens, A.4
Wilson, C.B.5
Bassetti, M.6
Aderem, A.7
-
132
-
-
0033458799
-
Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages
-
Underhill D.M., Ozinsky A., Smith K.D., and Aderem A. Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages. Proc. Natl. Acad. Sci. USA 96 (1999) 14459-14463
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14459-14463
-
-
Underhill, D.M.1
Ozinsky, A.2
Smith, K.D.3
Aderem, A.4
-
133
-
-
0030998098
-
Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1β
-
Vigers G.P., Anderson L.J., Caffes P., and Brandhuber B.J. Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1β. Nature 386 (1997) 190-194
-
(1997)
Nature
, vol.386
, pp. 190-194
-
-
Vigers, G.P.1
Anderson, L.J.2
Caffes, P.3
Brandhuber, B.J.4
-
134
-
-
0042733592
-
SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling
-
Wald D., Qin J., Zhao Z., Qian Y., Naramura M., Tian L., Towne J., Sims J.E., Stark G.R., and Li X. SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 4 (2003) 920-927
-
(2003)
Nat. Immunol.
, vol.4
, pp. 920-927
-
-
Wald, D.1
Qin, J.2
Zhao, Z.3
Qian, Y.4
Naramura, M.5
Tian, L.6
Towne, J.7
Sims, J.E.8
Stark, G.R.9
Li, X.10
-
135
-
-
0037432179
-
Identification of serum soluble ST2 receptor as a novel heart failure biomarker
-
Weinberg E.O., Shimpo M., Hurwitz S., Tominaga S., Rouleau J.L., and Lee R.T. Identification of serum soluble ST2 receptor as a novel heart failure biomarker. Circulation 107 (2003) 721-726
-
(2003)
Circulation
, vol.107
, pp. 721-726
-
-
Weinberg, E.O.1
Shimpo, M.2
Hurwitz, S.3
Tominaga, S.4
Rouleau, J.L.5
Lee, R.T.6
-
136
-
-
0032535214
-
A chicken homolog of mammalian interleukin-1β: cDNA cloning and purification of active recombinant protein
-
Weining K.C., Sick C., Kaspers B., and Staeheli P. A chicken homolog of mammalian interleukin-1β: cDNA cloning and purification of active recombinant protein. Eur. J. Biochem. 258 (1998) 994-1000
-
(1998)
Eur. J. Biochem.
, vol.258
, pp. 994-1000
-
-
Weining, K.C.1
Sick, C.2
Kaspers, B.3
Staeheli, P.4
-
137
-
-
0030938198
-
The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases)
-
Wesche H., Korherr C., Kracht M., Falk W., Resch K., and Martin M.U. The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases). J. Biol. Chem. 272 (1997) 7727-7731
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7727-7731
-
-
Wesche, H.1
Korherr, C.2
Kracht, M.3
Falk, W.4
Resch, K.5
Martin, M.U.6
-
138
-
-
3643120790
-
Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells
-
Xu D., Chan W.L., Leung B.P., Hunter D., Schulz K., Carter R.W., McInnes I.B., Robinson J.H., and Liew F.Y. Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells. J. Exp. Med. 188 (1998) 1485-1492
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1485-1492
-
-
Xu, D.1
Chan, W.L.2
Leung, B.P.3
Hunter, D.4
Schulz, K.5
Carter, R.W.6
McInnes, I.B.7
Robinson, J.H.8
Liew, F.Y.9
-
139
-
-
0027509505
-
Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin 1 receptor type 1
-
Yanagisawa K., Takagi T., Tsukamoto T., Tetsuka T., and Tominaga S. Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin 1 receptor type 1. FEBS Lett. 318 (1993) 83-87
-
(1993)
FEBS Lett.
, vol.318
, pp. 83-87
-
-
Yanagisawa, K.1
Takagi, T.2
Tsukamoto, T.3
Tetsuka, T.4
Tominaga, S.5
-
140
-
-
0032193770
-
IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: Synergism with IL-18 for IFN-γ production
-
Yoshimoto T., Takeda K., Tanaka T., Ohkusu K., Kashiwamura S., Okamura H., Akira S., and Nakanishi K. IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: Synergism with IL-18 for IFN-γ production. J. Immunol. 161 (1998) 3400-3407
-
(1998)
J. Immunol.
, vol.161
, pp. 3400-3407
-
-
Yoshimoto, T.1
Takeda, K.2
Tanaka, T.3
Ohkusu, K.4
Kashiwamura, S.5
Okamura, H.6
Akira, S.7
Nakanishi, K.8
-
141
-
-
0030613551
-
The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
-
Zandi E., Rothwarf D.M., Delhase M., Hayakawa M., and Karin M. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation. Cell 91 (1997) 243-252
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
Hayakawa, M.4
Karin, M.5
-
142
-
-
1542377424
-
A toll-like receptor that prevents infection by uropathogenic bacteria
-
Zhang D., Zhang G., Hayden M.S., Greenblatt M.B., Bussey C., Flavell R.A., and Ghosh S. A toll-like receptor that prevents infection by uropathogenic bacteria. Science 303 (2004) 1522-1526
-
(2004)
Science
, vol.303
, pp. 1522-1526
-
-
Zhang, D.1
Zhang, G.2
Hayden, M.S.3
Greenblatt, M.B.4
Bussey, C.5
Flavell, R.A.6
Ghosh, S.7
-
143
-
-
0033178370
-
Molecular cloning of interleukin 1β from rainbow trout Oncorhynchus mykiss reveals no evidence of an ice cut site
-
Zou J., Grabowski P.S., Cunningham C., and Secombes C.J. Molecular cloning of interleukin 1β from rainbow trout Oncorhynchus mykiss reveals no evidence of an ice cut site. Cytokine 11 (1999) 552-560
-
(1999)
Cytokine
, vol.11
, pp. 552-560
-
-
Zou, J.1
Grabowski, P.S.2
Cunningham, C.3
Secombes, C.J.4
-
144
-
-
0034072375
-
Molecular cloning of the gene for interleukin-1β from Xenopus laevis and analysis of expression in vivo and in vitro
-
Zou J., Bird S., Minter R., Horton J., Cunningham C., and Secombes C.J. Molecular cloning of the gene for interleukin-1β from Xenopus laevis and analysis of expression in vivo and in vitro. Immunogenetics 51 (2000) 332-338
-
(2000)
Immunogenetics
, vol.51
, pp. 332-338
-
-
Zou, J.1
Bird, S.2
Minter, R.3
Horton, J.4
Cunningham, C.5
Secombes, C.J.6
|