Secretion of intracellular IL-1 receptor antagonist (type 1) is dependent on P2X7 receptor activation

Journal of Immunology

Volumn 173, Issue 2, 2004, Pages 1202-1208

  Wilson, Heather L ^a   Francis, Sheila E ^b   Dower, Steven K ^a   Crossman, David C ^b  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; LACTATE DEHYDROGENASE; LIPOCORTIN 5; PHOSPHATIDYLSERINE; PURINE P2X7 RECEPTOR; SIGNAL PEPTIDE;

ANIMAL CELL; ARTERY WALL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOTHELIUM CELL; ENZYME ASSAY; EXTRACELLULAR CALCIUM; IMMUNOBLOTTING; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION;

EID: 3142757912     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.2.1202     Document Type: Article

References (42)

1. Arend, W. P. 2002, The balance between IL-1 and IL-1ra in disease. Cytokine Growth Factor Rev. 13:323.
2. Bevilacqua, M. P., J. S. Pober, G. R. Majeau, R. S. Cotran, and M. A. Gimbrone, Jr. 1984. Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells. J. Exp. Med. 160:618.
3. Galea, J., J. Armstrong, P. Gadsdon, H. Holden, S. E. Francis, and C. M. Holt. 1996. Interleukin-1β in coronary arteries of patients with ischemic heart disease. Arterioscler. Thromb. Vasc. Biol. 16:1000.
4. Dewberry, R., H. Holden, D. Crossman, and S. Francis. 2000. Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 20:2394.
5. Raines, E. W., S. K. Dower, and R. Ross. 1989. Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA. Science 243:393.
6. Elhage, R., A. Maret, M. T. Pieraggi, J. C. Thiers, J. F. Arnal, and F. Bayard. 1998. Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice. Circulation 97:242.
7. Kirii, H., T. Niwa, Y. Yamada, H. Wada, K. Saito, Y. Iwakura, M. Asano, H. Moriwaki, and M. Seishima. 2003. Lack of interleukin-1β decreases the severity of atherosclerosis in ApoE-deficient mice. Arterioscler. Thromb. Vasc. Biol. 23:656.
8. Haskill, S., G. Martin, L. Van Le, J. Morris, A. Peace, C. F. Bigler, G. J. Jaffe, C. Hammerberg, S. A. Sporn, S. Fong, et al. 1991. cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. Proc. Natl. Acad. Sci. USA 88:3681.
9. Muzio, M., N. Polentarutti, M. Sironi, G. Poli, L. De Gioia, M. Introna, A. Mantovani, and F. Colotta. 1995. Cloning and characterization of a new isoform of the interleukin 1 receptor antagonist. J. Exp. Med. 182:623.
10. Malyak, M., J. M. Guthridge, K. R. Hance, S. K. Dower, J. H. Freed, and W. P. Arend. 1998. Characterization of a low molecular weight isoform of IL-1 receptor antagonist. J. Immunol. 161:1997.
11. Malyak, M., M. F. Smith, Jr., A. A. Abel, K. R. Hance, and W. P. Arend. 1998. The differential production of three forms of IL-1 receptor antagonist by human neutrophils and monocytes. J. Immunol. 161:2004.
12. Perregaux, D., and C. A. Gabel. 1994. Interleukin-1β maturation and release in response to ATP and nigericin: evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J. Biol. Chem. 269:15195.
13. Griffiths, R. J., E. J. Stam, J. T. Downs, and I. G. Otterness. 1995. ATP induces the release of IL-1 from LPS-primed cells in vivo. J. Immunol. 154:2821.
14. Ferrari, D., P. Chiozzi, S. Falzoni, M. Dal Susino, L. Melchiorri, O. R. Baricordi, and F. Di Virgilio. 1997. Extracellular ATP triggers IL-1β release by activating the purinergic P2Z receptor of human macrophages. J. Immunol. 159:1451.
15. Laliberte, R. E., D. G. Perregaux, P. McNiff, and C. A. Gabel. 1997. Human monocyte ATP-induced IL-1β posttranslational processing is a dynamic process dependent on in vitro growth conditions. J. Leukocyte Biol. 62:227.
16. Di Virgilio, F., P. Chiozzi, S. Falzoni, D. Ferrari, J. M. Sanz, V. Venketaraman, and O. R. Baricordi. 1998. Cytolytic P2X purinoceptors. Cell Death Diffe. 5:191.
17. Perregaux, D. G., and C. A. Gabel. 1998. Post-translational processing of murine IL-1: evidence that ATP-induced release of IL-1α and IL-1β occurs via a similar mechanism. J. Immunol. 160:2469.
18. Perregaux, D. G., P. McNiff, R. Laliberte, M. Conklyn, and C. A. Gabel. 2000. ATP acts as an agonist to promote stimulus-induced secretion of IL-1β and IL-18 in human blood. J. Immunol. 165:615.
19. Sanz, J. M., and F. Di Virgilio. 2000. Kinetics and mechanism of ATP-dependent IL-1β release from microglial cells. J. Immunol. 164:4893.
20. Mehta, V. B., J. Hart, and M. D. Wewers. 2001. ATP-stimulated release of interleukin (IL)-1β and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage. J. Biol. Chem. 276:3820.
21. Le Feuvre, R., D. Brough, and N. Rothwell. 2002. Extracellular ATP and P2X7 receptors in neurodegeneration. Eur. J. Pharmacol. 447:261.
22. 7 receptors. J. Biol. Chem. 276:125.
23. 7 receptor alters leukocyte function and attenuates an inflammatory response. J. Immunol. 168:6436.
24. MacKenzie, A., H. L. Wilson, E. Kiss-Toth, S. K. Dower, R. A. North, and A. Surprenant. 2001. Rapid secretion of interleukin-1β by microvesicle shedding. Immunity 15:825.
25. Jaffe, E. A., R. L. Nachman, C. G. Becker, and C. R. Minick. 1973. Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria. J. Clin. Invest. 52:2745.
26. 7 receptors. Neurochem. Int. 33:209.
27. Hu, Y., P. L. Fisette, L. C. Denlinger, A. G. Guadarrama, J. A. Sommer, R. A. Proctor, and P. J. Bertics. 1998. Purinergic receptor modulation of lipopolysaccharide signaling and inducible nitric-oxide synthase expression in RAW 264.7 macrophages. J. Biol. Chem. 273:27170.
28. Ramirez, A. N., and D. L. Kunze. 2002. P2X purinergic receptor channel expression and function in bovine aortic endothelium. Am. J. Physiol. 282:H2106.
29. Schwiebert, L. M., W. C. Rice, B. A. Kudlow, A. L. Taylor, and E. M. Schwiebert. 2002. Extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells. Am. J. Physiol. 282:C289.
30. 7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1β release. J. Immunol. 170:5728.
31. 7-transfected HEK293 cells. Mol. Biol. Cell 14:2655.
32. 7 receptor. J. Physiol. 519(Pt. 2):335.
33. 2+ entry differentially contribute to the release of IL-1β and IL-1α from murine macrophages. J. Immunol. 170:3029.
34. Corradi, A., A. T. Franzi, and A. Rubartelli. 1995. Synthesis and secretion of interleukin-1α and interleukin-1 receptor antagonist during differentiation of cultured keratinocytes. Exp. Cell Res. 217:355.
35. Pastore, S., S. Corinti, M. La Placa, B. Didona, and G. Girolomoni. 1998. Interferon-γ promotes exaggerated cytokine production in keratinocytes cultured from patients with atopic dermatitis. J. Allergy Clin. Immunol. 101:538.
36. Levine, S. J., T. Wu, and J. H. Shelhamer. 1997. Extracellular release of the type I intracellular IL-1 receptor antagonist from human airway epithelial cells: differential effects of IL-4, IL-13, IFN-γ, and corticosteroids. J. Immunol. 158:5949.
37. Greig, A. V., C. Linge, A. Cambrey, and G. Burnstock. 2003. Purinergic receptors are part of a signaling system for keratinocyte proliferation, differentiation, and apoptosis in human fetal epidermis. J. Invest. Dermatol. 121:1145.
38. 7 receptor. Neuropharmacology 36:1277.
39. Bodin, P., and G. Burnstock. 1998. Increased release of ATP from endothelial cells during acute inflammation. Inflamm. Res. 47:351.
40. Bodin, P., and G. Burnstock. 1996. ATP-stimulated release of ATP by human endothelial cells. J. Cardiovasc. Pharmacol. 27:872.
41. Burnstock, G. 2002. Purinergic signaling and vascular cell proliferation and death. Arterioscler. Thromb. Vasc. Biol. 22:364.
42. Nicklin, M. J., D. E. Hughes, J. L. Barton, J. M. Ure, and G. W. Duff. 2000. Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene. J. Exp. Med 191:303.