Pancreatic β-cell damage mediated by β-cell production of interleukin-1: A novel mechanism for virus-induced diabetes

Journal of Biological Chemistry

Volumn 276, Issue 14, 2001, Pages 11151-11158

  Heitmeier, Monique R ^b   Arnush, Marc ^b   Scarim, Anna L ^b   Corbett, John A ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; IMMUNOLOGY; ORGANIC ACIDS; RNA; VIRUSES;

ISLET DEGENERATION; PANCREATIC CELL DAMAGE;

BIOCHEMISTRY;

DOUBLE STRANDED RNA; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA CONVERTING ENZYME; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; POLYINOSINIC POLYCYTIDYLIC ACID;

ANIMAL CELL; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVATION; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VIRUS INFECTION; VIRUS REPLICATION; ANIMAL; CELL CULTURE; CELL DEATH; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; METABOLISM; PANCREAS ISLET; PATHOLOGY; SPRAGUE DAWLEY RAT; VIROLOGY;

ANIMALIA; RNA VIRUSES;

ANIMALS; AUTOIMMUNITY; CELL DEATH; CELLS, CULTURED; DIABETES MELLITUS, TYPE 1; INTERLEUKIN-1; ISLETS OF LANGERHANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; VIRUS DISEASES;

EID: 0035815640     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009159200     Document Type: Article

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